Quantitative Rules for Parallel Calibration and Drift-Resilient Maintenance of Large-Scale Superconducting Quantum Processors
As superconducting quantum processors scale toward hundreds of qubits, manual calibration becomes increasingly costly and difficult to sustain. Here we address two system-level factors governing automated calibration, namely, crosstalk induced by parallel operations and temporal drift of control parameters. On a 66-qubit superconducting processor, cross-entropy benchmarking shows that single-qubit calibration tolerates full-chip concurrency with minimal fidelity loss, whereas CZ calibration requires a minimum coupler-graph distance of four to avoid elevated control errors. Continuous monitoring of representative qubit and coupler parameters further yields quantitative refresh rules that assign refresh priority by error-budget consumption. These results turn two conventionally heuristic choices, the concurrency density of calibration tasks and the refresh priority of each control parameter, into measurable operating rules. Implemented within an automated calibration framework, the rules support a six-qubit Greenberger-Horne-Zeilinger state with a zero-noise-extrapolated fidelity of 89.64%, distance-dependent logical-error suppression in a single-cycle repetition-code benchmark, and a reduction of the mean single-qubit error from 0.023 to 0.011 on a 337-qubit processor, providing an experimentally grounded reference for the automated calibration and maintenance of current and future large-scale superconducting quantum systems.