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Kwanhyung Lee

Publications and source records attributed to Kwanhyung Lee.

10 recordsLinked to original sources

Learning to Select Source-Traceable Evidence for Language-Model Prediction from Irregular Clinical Time Series

Numerical time-series models effectively process irregular electronic health record (EHR) trajectories, but do not expose which temporal patterns support each prediction as readable evidence. Existing text-based interfaces either serialize observations, preserving source traceability but offering limited clinical interpretation, or generate patient-level summaries that improve readability but can obscure links to source measurements. We introduce STEP-CTS (Source-Traceable Evidence for Prediction from Clinical Time-Series), which learns to select source-traceable text evidence for a language-model predictor. Multi-scale window statistics of each trajectory are verbalized as sets of deterministic threshold predicates, each set linked to its source window (e.g., "[5-7 h]: last temperature at least 38C"). An offline LLM, run once per unique predicate set without access to patient records, the prediction task, or outcome labels, attaches clinical concepts such as "fever" to their supporting predicates and abstains when none applies. Each predicate set, together with its concepts, forms an evidence unit. A learned Evidence Selector selects a fixed-size subset of the evidence units, which a pretrained clinical language-model encoder reads to make the prediction, with no patient-level text generation. Across three ICU benchmarks, STEP-CTS outperforms evaluated text-based baselines, improving AUPRC over the strongest by 5.1, 3.7, and 11.7 percentage points on P2012, MIMIC-III, and P2019, respectively, and is competitive with dedicated numerical time-series models. Ablations show that clinical concepts and learned evidence selection each contribute to predictive performance. In a blinded clinician study, the selected evidence is rated as traceable as deterministic serialization, near the ceiling of the scale, and above generated summaries on clinical interpretation.

cs.LG↗

Domain Generalization under Sampling Pattern Shifts in Irregular Time Series

Irregularly sampled multivariate time series (ISMTS) are prevalent in real-world applications, where both observation times and available measurements can vary substantially across domains. While recent models increasingly exploit such sampling information for prediction, its robustness under sampling pattern shifts remains underexplored. We introduce HAR-C, to the best of our knowledge the first controlled benchmark for sampling pattern shifts in ISMTS, and show that sampling shifts alone can substantially degrade performance, induce sampling-specific shortcuts, and remain challenging for existing domain generalization (DG) methods. Motivated by these findings, we propose PRISM, a DG framework that first learns complementary feature-centric and sampling-centric representations without task labels, and subsequently performs robust supervised training across diverse sampling variations to discourage brittle shortcut reliance. Extensive experiments on controlled and real-world ISMTS benchmarks demonstrate that PRISM consistently improves robustness to unseen sampling shifts over existing methods. Our code is available at https://anonymous.4open.science/r/PRISM.

cs.LG↗

ReviewScore: Misinformed Peer Review Detection with Large Language Models

Peer review serves as a backbone of academic research, but in most AI conferences, the review quality is degrading as the number of submissions explodes. To reliably detect low-quality reviews, we define misinformed review points as either "weaknesses" in a review that contain incorrect premises, or "questions" in a review that can be already answered by the paper. We verify that 15.2% of weaknesses and 26.4% of questions are misinformed and introduce ReviewScore indicating if a review point is misinformed. To evaluate the factuality of each premise of weaknesses, we propose an automated engine that reconstructs every explicit and implicit premise from a weakness. We build a human expert-annotated ReviewScore dataset to check the ability of LLMs to automate ReviewScore evaluation. Then, we measure human-model agreements on ReviewScore using eight current state-of-the-art LLMs. The models show F1 scores of 0.4--0.5 and kappa scores of 0.3--0.4, indicating moderate agreement but also suggesting that fully automating the evaluation remains challenging. A thorough disagreement analysis reveals that most errors are due to models' incorrect reasoning. We also prove that evaluating premise-level factuality shows significantly higher agreements than evaluating weakness-level factuality.

cs.CL↗

Structure-Aware Set Transformers: Temporal and Variable-Type Attention Biases for Asynchronous Clinical Time Series

Electronic health records (EHR) are irregular, asynchronous multivariate time series. As time-series foundation models increasingly tokenize events rather than discretizing time, the input layout becomes a key design choice. Grids expose time$\times$variable structure but require imputation or missingness masks, risking error or sampling-policy shortcuts. Point-set tokenization avoids discretization but loses within-variable trajectories and time-local cross-variable context (Fig.1). We restore these priors in STructure-AwaRe (STAR) Set Transformer by adding parameter-efficient soft attention biases: a temporal locality penalty $-|Δt|/τ$ with learnable timescales and a variable-type affinity $B_{s_i,s_j}$ from a learned feature-compatibility matrix. We benchmark 10 depth-wise fusion schedules (Fig.2). On three ICU prediction tasks, STAR-Set achieves AUC/APR of 0.7158/0.0026 (CPR), 0.9164/0.2033 (mortality), and 0.8373/0.1258 (vasopressor use), outperforming regular-grid, event-time grid, and prior set baselines. Learned $τ$ and $B$ provide interpretable summaries of temporal context and variable interactions, offering a practical plug-in for context-informed time-series models.

cs.LG↗

Soft Equivariance Regularization for Invariant Self-Supervised Learning

Self-supervised learning (SSL) typically learns representations invariant to semantic-preserving augmentations. While effective for recognition, enforcing strong invariance can suppress transformation-dependent structure that is useful for robustness to geometric perturbations and spatially sensitive transfer. A growing body of work, therefore, augments invariance-based SSL with equivariance objectives, but these objectives are often imposed on the same final representation. We empirically observe a trade-off in this coupled setting: pushing equivariance regularization toward deeper layers improves equivariance scores but degrades ImageNet-1k linear evaluation, motivating a layer-decoupled design. Motivated by this trade-off, we propose Soft Equivariance Regularization (SER), a plug-in regularizer that decouples where invariance and equivariance are enforced: we keep the base SSL objective unchanged on the final embedding, while softly encouraging equivariance on an intermediate spatial token map via analytically specified group actions $ρ_g$ applied directly in feature space. SER learns/predicts no per-sample transformation codes/labels, requires no auxiliary transformation-prediction head, and adds only 1.008x training FLOPs. On ImageNet-1k ViT-S/16 pretraining, SER improves MoCo-v3 by +0.84 Top-1 in linear evaluation under a strictly matched 2-view setting and consistently improves DINO and Barlow Twins; under matched view counts, SER achieves the best ImageNet-1k linear-eval Top-1 among the compared invariance+equivariance add-ons. SER further improves ImageNet-C/P by +1.11/+1.22 Top-1 and frozen-backbone COCO detection by +1.7 mAP. Finally, applying the same layer-decoupling recipe to existing invariance+equivariance baselinesimproves their accuracy, suggesting layer decoupling as a general design principle for combining invariance and equivariance.

cs.CV↗

EMR-AGENT: Automating Cohort and Feature Extraction from EMR Databases

Machine learning models for clinical prediction rely on structured data extracted from Electronic Medical Records (EMRs), yet this process remains dominated by hardcoded, database-specific pipelines for cohort definition, feature selection, and code mapping. These manual efforts limit scalability, reproducibility, and cross-institutional generalization. To address this, we introduce EMR-AGENT (Automated Generalized Extraction and Navigation Tool), an agent-based framework that replaces manual rule writing with dynamic, language model-driven interaction to extract and standardize structured clinical data. Our framework automates cohort selection, feature extraction, and code mapping through interactive querying of databases. Our modular agents iteratively observe query results and reason over schema and documentation, using SQL not just for data retrieval but also as a tool for database observation and decision making. This eliminates the need for hand-crafted, schema-specific logic. To enable rigorous evaluation, we develop a benchmarking codebase for three EMR databases (MIMIC-III, eICU, SICdb), including both seen and unseen schema settings. Our results demonstrate strong performance and generalization across these databases, highlighting the feasibility of automating a process previously thought to require expert-driven design. The code will be released publicly at https://github.com/AITRICS/EMR-AGENT/tree/main. For a demonstration, please visit our anonymous demo page: https://anonymoususer-max600.github.io/EMR_AGENT/

cs.DB↗

Compact and De-biased Negative Instance Embedding for Multi-Instance Learning on Whole-Slide Image Classification

Whole-slide image (WSI) classification is a challenging task because 1) patches from WSI lack annotation, and 2) WSI possesses unnecessary variability, e.g., stain protocol. Recently, Multiple-Instance Learning (MIL) has made significant progress, allowing for classification based on slide-level, rather than patch-level, annotations. However, existing MIL methods ignore that all patches from normal slides are normal. Using this free annotation, we introduce a semi-supervision signal to de-bias the inter-slide variability and to capture the common factors of variation within normal patches. Because our method is orthogonal to the MIL algorithm, we evaluate our method on top of the recently proposed MIL algorithms and also compare the performance with other semi-supervised approaches. We evaluate our method on two public WSI datasets including Camelyon-16 and TCGA lung cancer and demonstrate that our approach significantly improves the predictive performance of existing MIL algorithms and outperforms other semi-supervised algorithms. We release our code at https://github.com/AITRICS/pathology_mil.

cs.CV↗

Learning Missing Modal Electronic Health Records with Unified Multi-modal Data Embedding and Modality-Aware Attention

Electronic Health Record (EHR) provides abundant information through various modalities. However, learning multi-modal EHR is currently facing two major challenges, namely, 1) data embedding and 2) cases with missing modality. A lack of shared embedding function across modalities can discard the temporal relationship between different EHR modalities. On the other hand, most EHR studies are limited to relying only on EHR Times-series, and therefore, missing modality in EHR has not been well-explored. Therefore, in this study, we introduce a Unified Multi-modal Set Embedding (UMSE) and Modality-Aware Attention (MAA) with Skip Bottleneck (SB). UMSE treats all EHR modalities without a separate imputation module or error-prone carry-forward, whereas MAA with SB learns missing modal EHR with effective modality-aware attention. Our model outperforms other baseline models in mortality, vasopressor need, and intubation need prediction with the MIMIC-IV dataset.

cs.LG↗

Self-Supervised Predictive Coding with Multimodal Fusion for Patient Deterioration Prediction in Fine-grained Time Resolution

Accurate time prediction of patients' critical events is crucial in urgent scenarios where timely decision-making is important. Though many studies have proposed automatic prediction methods using Electronic Health Records (EHR), their coarse-grained time resolutions limit their practical usage in urgent environments such as the emergency department (ED) and intensive care unit (ICU). Therefore, in this study, we propose an hourly prediction method based on self-supervised predictive coding and multi-modal fusion for two critical tasks: mortality and vasopressor need prediction. Through extensive experiments, we prove significant performance gains from both multi-modal fusion and self-supervised predictive regularization, most notably in far-future prediction, which becomes especially important in practice. Our uni-modal/bi-modal/bi-modal self-supervision scored 0.846/0.877/0.897 (0.824/0.855/0.886) and 0.817/0.820/0.858 (0.807/0.81/0.855) with mortality (far-future mortality) and with vasopressor need (far-future vasopressor need) prediction data in AUROC, respectively.

cs.LG↗

Real-Time Seizure Detection using EEG: A Comprehensive Comparison of Recent Approaches under a Realistic Setting

Electroencephalogram (EEG) is an important diagnostic test that physicians use to record brain activity and detect seizures by monitoring the signals. There have been several attempts to detect seizures and abnormalities in EEG signals with modern deep learning models to reduce the clinical burden. However, they cannot be fairly compared against each other as they were tested in distinct experimental settings. Also, some of them are not trained in real-time seizure detection tasks, making it hard for on-device applications. Therefore in this work, for the first time, we extensively compare multiple state-of-the-art models and signal feature extractors in a real-time seizure detection framework suitable for real-world application, using various evaluation metrics including a new one we propose to evaluate more practical aspects of seizure detection models. Our code is available at https://github.com/AITRICS/EEG_real_time_seizure_detection.

cs.LG↗