arXiv subjects

Kyohei Yamada

Publications and source records attributed to Kyohei Yamada.

21 records · Page 2Linked to original sources

arXiv2023

Case-based Similar Image Retrieval for Weakly Annotated Large Histopathological Images of Malignant Lymphoma Using Deep Metric Learning

In the present study, we propose a novel case-based similar image retrieval (SIR) method for hematoxylin and eosin (H&E)-stained histopathological images of malignant lymphoma. When a whole slide image (WSI) is used as an input query, it is desirable to be able to retrieve similar cases by focusing on image patches in pathologically important regions such as tumor cells. To address this problem, we employ attention-based multiple instance learning, which enables us to focus on tumor-specific regions when the similarity between cases is computed. Moreover, we employ contrastive distance metric learning to incorporate immunohistochemical (IHC) staining patterns as useful supervised information for defining appropriate similarity between heterogeneous malignant lymphoma cases. In the experiment with 249 malignant lymphoma patients, we confirmed that the proposed method exhibited higher evaluation measures than the baseline case-based SIR methods. Furthermore, the subjective evaluation by pathologists revealed that our similarity measure using IHC staining patterns is appropriate for representing the similarity of H&E-stained tissue images for malignant lymphoma.

cs.CV↗

arXiv2021

Simons Observatory Small Aperture Telescope overview

The Simons Observatory (SO) is a cosmic microwave background (CMB) experiment from the Atacama Desert in Chile comprising three small-aperture telescopes (SATs) and one large-aperture telescope (LAT). In total, SO will field over 60,000 transition-edge sensor (TES) bolometers in six spectral bands centered between 27 and 280 GHz in order to achieve the sensitivity necessary to measure or constrain numerous cosmological quantities. In this work, we focus on the SATs which are optimized to search for primordial gravitational waves that are detected as parity-odd polarization patterns called a B-modes on degree scales in the CMB. Each SAT employs a single optics tube with TES arrays operating at 100 mK. The high throughput optics system has a 42 cm aperture and a 35-degree field of view coupled to a 36 cm diameter focal plane. The optics consist of three metamaterial anti-re ection coated silicon lenses. Cryogenic ring baffles with engineered blackbody absorbers are installed in the optics tube to minimize the stray light. The entire optics tube is cooled to 1 K. A cryogenic continuously rotating half-wave plate near the sky side of the aperture stop helps to minimize the effect of atmospheric uctuations. The telescope warm baffling consists of a forebaffle, an elevation stage mounted co-moving shield, and a fixed ground shield that together control the far side-lobes and mitigates ground-synchronous systematics. We present the status of the SAT development.

astro-ph.IM↗

arXiv2018

First demonstration of gamma-ray imaging using balloon-borne emulsion telescope

We promote the precise gamma-ray observation project Gamma-Ray Astro-Imager with Nuclear Emulsion (GRAINE), which uses balloon-borne emulsion gamma-ray telescopes. The emulsion telescope realizes observations with high angular resolution, polarization sensitivity, and large aperture area in the 0.01--100 GeV energy region. Herein, we report the data analysis of emulsion tracks and the first demonstration of gamma-ray imaging via an emulsion telescope by using the flight data from the balloon experiment performed in 2015 (GRAINE 2015). The emulsion films were scanned by the latest read-out system for a total area of 41 m$^2$ in three months, and then the gamma-ray event selection was automatically processed. Millions of electron-pair events are accumulated in the balloon-borne emulsion telescope. The emulsion telescope detected signals from a calibration source (gamma rays from the interaction of cosmic rays with an aluminum plate) with a high significance during the balloon observation and created a gamma-ray image consistent with the source size and the expected angular resolution in the energy range of 100--300 MeV. The flight performance obtained in the GRAINE 2015 experiment proves that balloon-borne emulsion telescope experiments with larger area are feasible while maintaining expected imaging performance.

astro-ph.IM↗