Search arXivSearch

arXiv subjects

Lei Zhang

Publications and source records attributed to Lei Zhang.

14 recordsLinked to original sources

Building evidence-based knowledge bases from full-text literature for disease-specific biomedical reasoning

Biomedical knowledge resources often either preserve evidence as unstructured text or compress it into flat triples that omit study design, provenance, and quantitative support. Here we present EvidenceNet, a disease-specific dataset of record-level evidence collections and corresponding graph representations derived from full-text biomedical literature. EvidenceNet uses a large language model (LLM)-assisted pipeline to extract experimentally grounded findings as structured evidence records, normalize biomedical entities, score evidence quality, and connect related records through typed semantic relations. We release EvidenceNet-HCC with 7,872 evidence records and a corresponding graph with 10,328 nodes and 49,756 edges, and EvidenceNet-CRC with 6,622 records and a corresponding graph with 8,795 nodes and 39,361 edges. Technical validation shows high component fidelity, including 98.3% field-level extraction accuracy, 100.0% high-confidence entity-link accuracy, 87.5% fusion integrity, and 90.0% semantic relation-type accuracy. Downstream analyses show that the data support retrieval-augmented question answering and graph-based tasks such as future link prediction and target prioritization. These results establish EvidenceNet as a disease-specific biomedical knowledge base dataset for evidence-aware analysis and reuse.

cs.CE

Hand-Object Interaction in the Age of Large Foundation Models:Reconstruction, Generation, and Embodied Transfer

Hand-object interaction (HOI) modeling remains challenging because it requires joint reasoning about hand articulation, object geometry, contact, semantics, and dynamics under severe visual uncertainty. Foundation models introduce transferable prior knowledge learned from large-scale cross-domain data, offering new ways to address these challenges beyond task-specific data and models. However, the rapidly growing literature remains fragmented, and existing studies typically describe these methods simply as ``using large models'' without systematically characterizing what knowledge is introduced, where it enters the HOI pipeline, or which HOI uncertainty it helps reduce. This survey presents the first systematic review of foundation-model priors for HOI. We organize the literature into six HOI tasks spanning reconstruction and generation. More importantly, we establish a taxonomy of eight foundation-model sub-priors grouped into geometric, semantic, and visual families. Geometric priors encompass shape retrieval, shape reconstruction, and spatial reconstruction; semantic priors include semantic grounding and language reasoning; and visual priors cover visual representation, image generation, and video generation. Based on this taxonomy, we systematically analyze how different priors are represented, injected, and adapted across HOI pipelines and tasks. Beyond how foundation models empower HOI, we further examine how HOI-derived knowledge is used in robot learning, including human-data pretraining, human-to-robot skill transfer, and HOI-to-robot data generation. Finally, we summarize datasets and evaluation protocols, and discuss limitations and future directions toward more generalizable HOI systems. To support long-term progress, we curate a live repository that continuously aggregates emerging methods and benchmarks.

cs.CV

Simulation-free Unbalanced Dynamic Optimal Transport with General Growth Penalty

Inferring cellular dynamics from unpaired single-cell snapshots requires modeling both state transitions and population growth or death. Unbalanced dynamic optimal transport (UDOT) addresses this by penalizing growth along transport paths, making the choice of growth penalty a key way to encode biological priors on proliferation and apoptosis. However, existing UDOT solvers either rely on computationally expensive NeuralODE simulations or depend on analytical solutions of conditional paths, restricting their efficiency solely to quadratic penalties, i.e. Wasserstein-Fisher-Rao (WFR) geodesics. To enable an efficient UDOT solver for general growth penalties, we first show that concave growth penalties lead to degenerate solutions where growth and transport are separated. We then introduce \textbf{S}imulation-free \textbf{U}nbalanced \textbf{D}ynamic \textbf{O}ptimal transport (SUDO), a simulation-free framework for UDOT with general non-quadratic convex growth penalties. SUDO learns the conditional paths and transport costs, solves the induced semi-coupling problem, and subsequently leverages unbalanced flow matching to achieve a simulation-free solution. On WFR benchmarks, SUDO matches the accuracy of efficient, analytical solution-driven algorithms while outperforming simulation-based methods in computational speed. Beyond WFR, SUDO supports asymmetric penalties that encode proliferation-dominant priors and produce more plausible trajectories and growth estimates on synthetic and single-cell datasets.

cs.LG

Computing stable configurations of confined smectic liquid crystals with a deep variational framework

Smectic liquid crystals are layered liquid-crystalline phases characterized by orientational order and periodic density modulation. Although their structures can be modeled using continuum theories, computing stable configurations remains challenging in complex geometries, particularly when the high-frequency density modulations associated with smectic layering should be resolved. We propose a deep variational framework (DVF) for computing these configurations within the modified Landau--de Gennes model, in which the coupled orientational and positional order parameters are represented on a regular reference domain while physical confinement is incorporated through coordinate mappings. A warmup penalty mitigates the spectral bias of neural networks toward smooth, nonlayered fields, enabling robust recovery of oscillatory smectic states. Comparisons with a neural-network baseline and finite-difference relaxation demonstrate the essential role of this penalty and the numerical stability of the resulting layered states. The DVF reproduces experimentally established smectic-A defect structures and layer morphologies across diverse confinement geometries and further predicts a chevron-like smectic-C state in a tangent-anchored sphere. Together, these results demonstrate the applicability of the DVF to computing stable smectic configurations across experimentally relevant confinement geometries and anchoring conditions.

cond-mat.soft

Towards Open-World Referring Expression Comprehension: A Benchmark with Training-free Multi-task Consistency Checker

Referring expression comprehension (REC) aims to localize a target object within an image based on a given expression. Although recent advances in vision-language models have led to substantial improvements in REC tasks, current REC benchmarks often hold simple scenarios and the assumption that each expression maps to a unique object. These limitations hinder the deployment of REC models in open-world environments. To fill this gap, we introduce OpenRef, a new benchmark for REC in complex visual and linguistic scenarios. OpenRef features three key advancements: 1) Diverse visual scenarios: spanning diverse visual domains, including ground views, drone views, dark scenes and adverse weather conditions; 2) Variable target counts: breaking the single-target limitation with multi-target and none-target samples; 3) Rich vocabulary types: incorporating proper nouns, polysemous words and ordinal terms to fit a wider range of expression needs. Furthermore, as traditional metrics are insufficient for open-world setting, we leverage F1 to measure grounding accuracy and propose N3R (Negative Relative Rejection Reliability) to assess relative rejection reliability against negative expressions. Finally, we introduce Multi-task Consistency Checker (MCC), a training-free but plug-and-play strategy that enhances model performance with one click by enforcing consistency self-verification. Extensive experiments demonstrate that this work significantly advances the performance of existing REC models in complex scenarios, paving the way for open-world REC. Project page: https://zongjianwu.github.io/openref

cs.CV

Structure and Implementation of New Practical English Textbooks Driven by Artificial Intelligence

Artificial intelligence is changing the form of applied English materials from fixed paper sequences to adaptive learning systems that can diagnose learners, recommend tasks, and provide formative feedback. This paper studies the structure and application of a new practical English textbook driven by artificial intelligence. A five-layer architecture is proposed: knowledge mapping, learner profiling, task generation, feedback orchestration, and teacher-side governance. A prototype was tested on 186 non-English-major undergraduates for eight weeks of teaching. Compared with a static digital textbook, the proposed system increased the unit completion accuracy from 72.4% to 84.9%, raised the average score for speaking tasks by 10.8 points, and reduced the teacher's correction time by 31.6%. Therefore, an AI-driven textbook can maintain the stability of the curriculum while providing personalised learning paths, rich practice materials and traceable classroom data.

cs.AI

Real-Time Shape Control of Multi-Segment Soft Robotic Arms Using Koopman Operators with Global and Local Observables

Multi-segment soft robotic arms can continuously reconfigure their body shapes for safe interaction, but tip control alone is insufficient for constrained-space tasks. Therefore, shape control is a more important task for multi-segment soft arms than tip control, but remains challenging due to the high dimensionality and nonlinear dynamics of continuum deformation. In existing work, shape control accuracy is defined by the error in the global frame (global shape error). For multi-segment soft arms, using only global shape error as the control objective is insufficient, as segment coupling, gravity-induced loading, and inertial effects become more significant. This difficulty increases with the number of segments. In this paper, we present a Koopman-based model predictive control framework that combines global and local observables, enabling real-time shape control on multi-segment soft robotic arms. The framework is evaluated through numerical and physical experiments. Numerical experiments demonstrate the scalability of the proposed controller by achieving shape control on robots with up to 10 independently actuated segments. The physical experiments demonstrate that the controller is capable of (1) real-time shape control of 3- and 5-segment robotic arms with tip speeds up to 0.6 m/s, (2) robust tracking without retraining, including distal payloads up to 400~g and recovery from a 7~N lateral disturbance, and (3) the potential for future inspection applications through a confined-space demonstration. These results demonstrate that the proposed framework enables dynamic, scalable, and accurate real-time shape control on multi-segment soft robotic arms.

cs.RO

When Irrelevant Text Matters: Affine Margin Shifts in Multimodal Large Language Models

Multimodal large language models (MLLMs) are frequently exposed to auxiliary textual context, the impact of which on visually grounded tasks remains underexplored. In this paper, we investigate the influence of task-irrelevant context by formulating it as a controlled intervention within a binary visual judgment framework. By maintaining an invariant prompt structure while varying auxiliary inputs, we observe that irrelevant text consistently biases model predictions across diverse benchmarks. To move beyond performance metrics, we characterize this sensitivity through a decision margin defined by the log-probability difference between binary candidates. Our analysis reveals a robust geometric regularity: contextconditioned margins follow a consistent affine transformation of their context-free counterparts. This finding demonstrates that irrelevant context does not manifest as unstructured stochastic noise but as a estimable distortion of model preference. We further interpret the fitted affine parameters as metrics for visual commitment preservation and directional answer bias. These findings provide a margin-level diagnostic view of irrelevant-context effects in MLLMs and offer a basis for future studies on noisy-context robustness

cs.CL

ByteX: A Unified AI Search Engine at ByteDance

Since 2016, ByteX has been the foundation of ByteDance's search infrastructure, scaling to more than 7,000 clusters and 300 PB of indexed data. Driven by the demands of AI workloads, ByteX has evolved from a text search engine into a unified AI search system supporting vector retrieval, lexical matching, and predicate filtering. Its largest deployment indexes nearly one trillion high-dimensional vectors. This scale exposes two central bottlenecks in AI-era retrieval: memory-intensive graph-index construction under sustained ingestion, and the prohibitive cost of keeping vector indexes entirely in memory. ByteX addresses these bottlenecks with two techniques. First, it introduces a quantization-aware vector kernel based on SymRaBitQ, a new symmetric quantization scheme with tight theoretical guarantees that allows index construction to run directly in the quantized space accurately and efficiently without retaining a copy of full-precision vectors. Second, it provides a hybrid storage engine that supports memory-resident, hybrid, and SSD-resident deployments, with fine-grained record-level caching to trade memory for latency under operational control. On large-scale benchmarks, ByteX improves throughput by up to 3x, reduces indexing memory by 80%, and lowers operating cost by 86% compared with prior systems, while supporting trillion-vector scale, write-heavy or latency-sensitive workloads in production.

cs.DB

Dyn-3D: Unveiling and Resolving Ego-Motion Ambiguity in Vision-Language Models

As Vision-Language Models (VLMs) tackle dynamic 3D spatial reasoning, ego-motion perception becomes essential to resolve monocular scale ambiguity. However, current models often overfit to smooth trajectory priors rather than genuinely understanding physical motion. Consequently, their spatial reasoning degrades severely under large displacements, a phenomenon we term Kinematic Collapse. This failure stems from spurious visual-motion correlations in natural videos and a lack of explicit physical supervision. To evaluate this, we introduce Dyn-3D, a benchmark using counterfactual 3D rendering to rigorously decouple visual changes from true kinematic properties. Furthermore, we propose the TempoVista framework, featuring the Kinematic-GSPO algorithm. By embedding metric physical ground truth into policy optimization, TempoVista explicitly grounds visual representations in 3D space. Experiments demonstrate that our approach significantly improves both motion estimation and robust spatial reasoning by utilizing camera dynamics as an effective geometric calibration signal.

cs.CV

Seeing the World and the Self from Egocentric Video

Complete 3D perception from egocentric video requires recovering the surrounding scene and the wearer's full-body motion in a shared metric frame. Existing methods typically address scene reconstruction and motion estimation separately: scene reconstruction methods ignore the wearer, whereas motion estimation methods lack explicit scene geometry and often depend on external trajectories. Joint recovery is challenging because the two tasks exhibit asymmetric visibility and require different prediction paradigms. The largely visible scene supports deterministic geometric regression, whereas the severely occluded body requires generative motion inference. We therefore propose RESELF (REconstructing the Scene and the sELF), a unified framework that couples deterministic metric geometry reconstruction with geometry-conditioned motion generation. RESELF adapts a geometry foundation model pre-trained on large-scale exocentric data to egocentric video using frame-wise scale and relative-pose consistency objectives. The resulting camera trajectory and latent geometric features condition a diffusion model that recovers the wearer's motion. A subsequent closed-loop kinematic feedback stage further refines the camera head while preserving the reconstructed scene geometry. To support training and evaluation, we curate EE4D-JSM from EgoExo4D by aligning egocentric video, sparse metric scene geometry, camera trajectories, and full-body motion annotations. Experiments show that RESELF outperforms state-of-the-art methods designed for the individual tasks across depth estimation, camera tracking, and full-body motion estimation. Code, models, and datasets will be available at https://ka1guan.github.io/RESELF/.

cs.CV

Coordinated Motion Planning for Multi-Arm Systems via Iterative LQ Games

Multi-agent motion planning for high-degree-of-freedom robotics manipulators in shared workspaces remains a fundamental yet challenging problem. Centralized planners often suffer from poor scalability, while decentralized approaches face robustness and safety concerns. Game-theoretic formulations offer a promising approach for modeling agent interactions, potentially overcoming these limitations. However, their application to articulated multi-arm systems remains limited. This paper presents an iterative Linear Quadratic (LQ) game framework for multi-manipulator motion planning, where each manipulator is modeled as an independent agent optimizing its own objective while interacting with other agents based on shared global states and collision constraints. The method solves a series of local LQ games by linearizing the dynamics and approximating the cost around a nominal trajectory, with Riccati backward recursions yielding feedback Nash strategies. To address the challenges of articulated systems, we incorporate differentiable penalties for self-collision and inter-arm collision into the optimization pipeline, enabling coordinated, collision-aware trajectory generation. Experiments demonstrate that our framework produces smooth, safe, and efficient trajectories in high-dimensional settings, outperforming traditional methods. This highlights the effectiveness of differential game formulations for multi-robot manipulation.

cs.RO

Can Large Language Models Identify Meaningful Touchpoints in Conversion Attribution?

Touchpoint selection in conversion attribution, namely identifying meaningful touchpoints contributing to conversions, is essential for e-commerce recommendation and online advertising. Current selection methods rely heavily on collaborative-filtering-based heuristics, which fail to align with user-perceived semantic intent. Through human annotation, we reveal a significant semantic gap: many implicitly-related, semantically relevant touchpoints remain undetected by existing rules. Therefore, we systematically evaluate the capability of Large Language Models (LLMs) in identifying these hidden associations. Our evaluation shows that while LLMs effectively uncover a substantial portion of implicitly-related touchpoints, significant room for improvement remains in their selection performance. Furthermore, we analyze the impact of different prompting strategies and foundation model choices on identification performance, providing valuable insights into their reasoning patterns and effectiveness. These insights offer a new roadmap for transitioning conversion attribution from mechanical rule-matching to human-aligned semantic reasoning. Moreover, we leverage the LLM-attributed conversion labels for enhancing industrial CVR model training and achieve significant offline performance gains, showing the potential of LLMs in conversion attribution.

cs.CL

Toward expert-level motivational interviewing for health behavior improvement with LLMs

Background: Motivational interviewing (MI) is an effective counseling approach for promoting health behavior change, but its impact is constrained by the need for highly trained human counselors. Objective: This study aimed to explore a scalable alternative by developing and evaluating Large Language Models for Motivational Interviewing (MI-LLMs). Methods: We first curated five Chinese psychological counseling corpora and, using GPT-4 with an MI-informed prompt, transcribed multi-turn dialogues from the two highest-quality datasets (CPsyCounD and PsyDTCorpus) into 2,040 MI-style counseling conversations, of which 2,000 were used for training and 40 for testing. Three Chinese-capable open-source LLMs (Baichuan2-7B-Chat, ChatGLM-4-9B-Chat and Llama-3-8B-Chinese-Chat-v2) were fine-tuned on this corpus and were named as MI-LLMs. We evaluated MI-LLMs using round-based automatic metrics and expert manual coding with the Motivational Interviewing Treatment Integrity (MITI) Coding Manual 4.2.1. Results: Across all three models, fine-tuning substantially improved BLEU-4 and ROUGE scores compared with the base models, and manual coding showed that MI-LLMs achieved technical and relational global scores, and MI-adherent ratios that approached those of real MI dialogues, although complex reflections and reflection-to-question ratios remained less frequent. Conclusions: These findings provide initial evidence that MI-oriented fine-tuning can endow general-purpose LLMs with core MI-consistent counseling behaviors, suggesting a scalable pathway toward AI-assisted health behavior change support while underscoring the need for further work on data scale, complex MI skills and real-world intervention trials.

cs.CL