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Li Sun

Publications and source records attributed to Li Sun.

At least 109 records · Page 6Linked to original sources

Clinically Interpretable Mortality Prediction for ICU Patients with Diabetes and Atrial Fibrillation: A Machine Learning Approach

Background: Patients with both diabetes mellitus (DM) and atrial fibrillation (AF) face elevated mortality in intensive care units (ICUs), yet models targeting this high-risk group remain limited. Objective: To develop an interpretable machine learning (ML) model predicting 28-day mortality in ICU patients with concurrent DM and AF using early-phase clinical data. Methods: A retrospective cohort of 1,535 adult ICU patients with DM and AF was extracted from the MIMIC-IV database. Data preprocessing involved median/mode imputation, z-score normalization, and early temporal feature engineering. A two-step feature selection pipeline-univariate filtering (ANOVA F-test) and Random Forest-based multivariate ranking-yielded 19 interpretable features. Seven ML models were trained with stratified 5-fold cross-validation and SMOTE oversampling. Interpretability was assessed via ablation and Accumulated Local Effects (ALE) analysis. Results: Logistic regression achieved the best performance (AUROC: 0.825; 95% CI: 0.779-0.867), surpassing more complex models. Key predictors included RAS, age, bilirubin, and extubation. ALE plots showed intuitive, non-linear effects such as age-related risk acceleration and bilirubin thresholds. Conclusion: This interpretable ML model offers accurate risk prediction and clinical insights for early ICU triage in patients with DM and AF.

cs.LG↗

LIFEBench: Evaluating Length Instruction Following in Large Language Models

While large language models (LLMs) can solve PhD-level reasoning problems over long context inputs, they still struggle with a seemingly simpler task: following explicit length instructions-e.g., write a 10,000-word novel. Additionally, models often generate far too short outputs, terminate prematurely, or even refuse the request. Existing benchmarks focus primarily on evaluating generations quality, but often overlook whether the generations meet length constraints. To this end, we introduce Length Instruction Following Evaluation Benchmark (LIFEBench) to comprehensively evaluate LLMs' ability to follow length instructions across diverse tasks and a wide range of specified lengths. LIFEBench consists of 10,800 instances across 4 task categories in both English and Chinese, covering length constraints ranging from 16 to 8192 words. We evaluate 26 widely-used LLMs and find that most models reasonably follow short-length instructions but deteriorate sharply beyond a certain threshold. Surprisingly, almost all models fail to reach the vendor-claimed maximum output lengths in practice, as further confirmed by our evaluations extending up to 32K words. Even long-context LLMs, despite their extended input-output windows, counterintuitively fail to improve length-instructions following. Notably, Reasoning LLMs outperform even specialized long-text generation models, achieving state-of-the-art length following. Overall, LIFEBench uncovers fundamental limitations in current LLMs' length instructions following ability, offering critical insights for future progress.

cs.CL↗

Enhancing Biomedical Multi-modal Representation Learning with Multi-scale Pre-training and Perturbed Report Discrimination

Vision-language models pre-trained on large scale of unlabeled biomedical images and associated reports learn generalizable semantic representations. These multi-modal representations can benefit various downstream tasks in the biomedical domain. Contrastive learning is widely used to pre-train vision-language models for general natural images and associated captions. Despite its popularity, we found biomedical texts have complex and domain-specific semantics that are often neglected by common contrastive methods. To address this issue, we propose a novel method, perturbed report discrimination, for pre-train biomedical vision-language models. First, we curate a set of text perturbation methods that keep the same words, but disrupt the semantic structure of the sentence. Next, we apply different types of perturbation to reports, and use the model to distinguish the original report from the perturbed ones given the associated image. Parallel to this, we enhance the sensitivity of our method to higher level of granularity for both modalities by contrasting attention-weighted image sub-regions and sub-words in the image-text pairs. We conduct extensive experiments on multiple downstream tasks, and our method outperforms strong baseline methods. The results demonstrate that our approach learns more semantic meaningful and robust multi-modal representations.

cs.CV↗

Development of Interactive Nomograms for Predicting Short-Term Survival in ICU Patients with Aplastic Anemia

Aplastic anemia is a rare, life-threatening hematologic disorder characterized by pancytopenia and bone marrow failure. ICU admission in these patients often signals critical complications or disease progression, making early risk assessment crucial for clinical decision-making and resource allocation. In this study, we used the MIMIC-IV database to identify ICU patients diagnosed with aplastic anemia and extracted clinical features from five domains: demographics, synthetic indicators, laboratory results, comorbidities, and medications. Over 400 variables were reduced to seven key predictors through machine learning-based feature selection. Logistic regression and Cox regression models were constructed to predict 7-, 14-, and 28-day mortality, and their performance was evaluated using AUROC. External validation was conducted using the eICU Collaborative Research Database to assess model generalizability. Among 1,662 included patients, the logistic regression model demonstrated superior performance, with AUROC values of 0.8227, 0.8311, and 0.8298 for 7-, 14-, and 28-day mortality, respectively, compared to the Cox model. External validation yielded AUROCs of 0.7391, 0.7119, and 0.7093. Interactive nomograms were developed based on the logistic regression model to visually estimate individual patient risk. In conclusion, we identified a concise set of seven predictors, led by APS III, to build validated and generalizable nomograms that accurately estimate short-term mortality in ICU patients with aplastic anemia. These tools may aid clinicians in personalized risk stratification and decision-making at the point of care.

cs.LG↗

DragLoRA: Online Optimization of LoRA Adapters for Drag-based Image Editing in Diffusion Model

Drag-based editing within pretrained diffusion model provides a precise and flexible way to manipulate foreground objects. Traditional methods optimize the input feature obtained from DDIM inversion directly, adjusting them iteratively to guide handle points towards target locations. However, these approaches often suffer from limited accuracy due to the low representation ability of the feature in motion supervision, as well as inefficiencies caused by the large search space required for point tracking. To address these limitations, we present DragLoRA, a novel framework that integrates LoRA (Low-Rank Adaptation) adapters into the drag-based editing pipeline. To enhance the training of LoRA adapters, we introduce an additional denoising score distillation loss which regularizes the online model by aligning its output with that of the original model. Additionally, we improve the consistency of motion supervision by adapting the input features using the updated LoRA, giving a more stable and accurate input feature for subsequent operations. Building on this, we design an adaptive optimization scheme that dynamically toggles between two modes, prioritizing efficiency without compromising precision. Extensive experiments demonstrate that DragLoRA significantly enhances the control precision and computational efficiency for drag-based image editing. The Codes of DragLoRA are available at: https://github.com/Sylvie-X/DragLoRA.

cs.CV↗

Unsupervised Graph Clustering with Deep Structural Entropy

Research on Graph Structure Learning (GSL) provides key insights for graph-based clustering, yet current methods like Graph Neural Networks (GNNs), Graph Attention Networks (GATs), and contrastive learning often rely heavily on the original graph structure. Their performance deteriorates when the original graph's adjacency matrix is too sparse or contains noisy edges unrelated to clustering. Moreover, these methods depend on learning node embeddings and using traditional techniques like k-means to form clusters, which may not fully capture the underlying graph structure between nodes. To address these limitations, this paper introduces DeSE, a novel unsupervised graph clustering framework incorporating Deep Structural Entropy. It enhances the original graph with quantified structural information and deep neural networks to form clusters. Specifically, we first propose a method for calculating structural entropy with soft assignment, which quantifies structure in a differentiable form. Next, we design a Structural Learning layer (SLL) to generate an attributed graph from the original feature data, serving as a target to enhance and optimize the original structural graph, thereby mitigating the issue of sparse connections between graph nodes. Finally, our clustering assignment method (ASS), based on GNNs, learns node embeddings and a soft assignment matrix to cluster on the enhanced graph. The ASS layer can be stacked to meet downstream task requirements, minimizing structural entropy for stable clustering and maximizing node consistency with edge-based cross-entropy loss. Extensive comparative experiments are conducted on four benchmark datasets against eight representative unsupervised graph clustering baselines, demonstrating the superiority of the DeSE in both effectiveness and interpretability.

cs.LG↗

Predicting ICU Readmission in Acute Pancreatitis Patients Using a Machine Learning-Based Model with Enhanced Clinical Interpretability

Acute pancreatitis (AP) is a common and potentially life-threatening gastrointestinal disease that imposes a significant burden on healthcare systems. ICU readmissions among AP patients are common, especially in severe cases, with rates exceeding 40%. Identifying high-risk patients for readmission is crucial for improving outcomes. This study used the MIMIC-III database to identify ICU admissions for AP based on diagnostic codes. We applied a preprocessing pipeline including missing data imputation, correlation analysis, and hybrid feature selection. Recursive Feature Elimination with Cross-Validation (RFECV) and LASSO regression, supported by expert review, reduced over 50 variables to 20 key predictors, covering demographics, comorbidities, lab tests, and interventions. To address class imbalance, we used the Synthetic Minority Over-sampling Technique (SMOTE) in a five-fold cross-validation framework. We developed and optimized six machine learning models-Logistic Regression, k-Nearest Neighbors, Naive Bayes, Random Forest, LightGBM, and XGBoost-using grid search. Model performance was evaluated with AUROC, accuracy, F1 score, sensitivity, specificity, PPV, and NPV. XGBoost performed best, with an AUROC of 0.862 (95% CI: 0.800-0.920) and accuracy of 0.889 (95% CI: 0.858-0.923) on the test set. An ablation study showed that removing any feature decreased performance. SHAP analysis identified platelet count, age, and SpO2 as key predictors of readmission. This study shows that ensemble learning, informed feature selection, and handling class imbalance can improve ICU readmission prediction in AP patients, supporting targeted post-discharge interventions.

stat.AP↗

Machine Learning-Based Prediction of Mortality in Geriatric Traumatic Brain Injury Patients

Traumatic Brain Injury (TBI) is a major contributor to mortality among older adults, with geriatric patients facing disproportionately high risk due to age-related physiological vulnerability and comorbidities. Early and accurate prediction of mortality is essential for guiding clinical decision-making and optimizing ICU resource allocation. In this study, we utilized the MIMIC-III database to identify geriatric TBI patients and applied a machine learning framework to develop a 30-day mortality prediction model. A rigorous preprocessing pipeline-including Random Forest-based imputation, feature engineering, and hybrid selection-was implemented to refine predictors from 69 to 9 clinically meaningful variables. CatBoost emerged as the top-performing model, achieving an AUROC of 0.867 (95% CI: 0.809-0.922), surpassing traditional scoring systems. SHAP analysis confirmed the importance of GCS score, oxygen saturation, and prothrombin time as dominant predictors. These findings highlight the value of interpretable machine learning tools for early mortality risk stratification in elderly TBI patients and provide a foundation for future clinical integration to support high-stakes decision-making in critical care.

q-bio.QM↗

Unfolded Deep Graph Learning for Networked Over-the-Air Computation

Over-the-air computation (AirComp) has emerged as a promising technology that enables simultaneous transmission and computation through wireless channels. In this paper, we investigate the networked AirComp in multiple clusters allowing diversified data computation, which is yet challenged by the transceiver coordination and interference management therein. Particularly, we aim to maximize the multi-cluster weighted-sum AirComp rate, where the transmission scalar as well as receive beamforming are jointly investigated while addressing the interference issue. From an optimization perspective, we decompose the formulated problem and adopt the alternating optimization technique with an iterative process to approximate the solution. Then, we reinterpret the iterations through the principle of algorithm unfolding, where the channel condition and mutual interference in the AirComp network constitute an underlying graph. Accordingly, the proposed unfolding architecture learns the weights parameterized by graph neural networks, which is trained through stochastic gradient descent approach. Simulation results show that our proposals outperform the conventional schemes, and the proposed unfolded graph learning substantially alleviates the interference and achieves superior computation performance, with strong and efficient adaptation to the dynamic and scalable networks.

eess.SP↗

SparseMeXT Unlocking the Potential of Sparse Representations for HD Map Construction

Recent advancements in high-definition \emph{HD} map construction have demonstrated the effectiveness of dense representations, which heavily rely on computationally intensive bird's-eye view \emph{BEV} features. While sparse representations offer a more efficient alternative by avoiding dense BEV processing, existing methods often lag behind due to the lack of tailored designs. These limitations have hindered the competitiveness of sparse representations in online HD map construction. In this work, we systematically revisit and enhance sparse representation techniques, identifying key architectural and algorithmic improvements that bridge the gap with--and ultimately surpass--dense approaches. We introduce a dedicated network architecture optimized for sparse map feature extraction, a sparse-dense segmentation auxiliary task to better leverage geometric and semantic cues, and a denoising module guided by physical priors to refine predictions. Through these enhancements, our method achieves state-of-the-art performance on the nuScenes dataset, significantly advancing HD map construction and centerline detection. Specifically, SparseMeXt-Tiny reaches a mean average precision \emph{mAP} of 55.5% at 32 frames per second \emph{fps}, while SparseMeXt-Base attains 65.2% mAP. Scaling the backbone and decoder further, SparseMeXt-Large achieves an mAP of 68.9% at over 20 fps, establishing a new benchmark for sparse representations in HD map construction. These results underscore the untapped potential of sparse methods, challenging the conventional reliance on dense representations and redefining efficiency-performance trade-offs in the field.

cs.CV↗

Seaweed-7B: Cost-Effective Training of Video Generation Foundation Model

This technical report presents a cost-efficient strategy for training a video generation foundation model. We present a mid-sized research model with approximately 7 billion parameters (7B) called Seaweed-7B trained from scratch using 665,000 H100 GPU hours. Despite being trained with moderate computational resources, Seaweed-7B demonstrates highly competitive performance compared to contemporary video generation models of much larger size. Design choices are especially crucial in a resource-constrained setting. This technical report highlights the key design decisions that enhance the performance of the medium-sized diffusion model. Empirically, we make two observations: (1) Seaweed-7B achieves performance comparable to, or even surpasses, larger models trained on substantially greater GPU resources, and (2) our model, which exhibits strong generalization ability, can be effectively adapted across a wide range of downstream applications either by lightweight fine-tuning or continue training. See the project page at https://seaweed.video/

cs.CV↗

Self-evolving Agents with reflective and memory-augmented abilities

Large language models (LLMs) have made significant advances in the field of natural language processing, but they still face challenges such as continuous decision-making. In this research, we propose a novel framework by integrating iterative feedback, reflective mechanisms, and a memory optimization mechanism based on the Ebbinghaus forgetting curve, it significantly enhances the agents' capabilities in handling multi-tasking and long-span information.

cs.CL↗

RiemannGFM: Learning a Graph Foundation Model from Riemannian Geometry

The foundation model has heralded a new era in artificial intelligence, pretraining a single model to offer cross-domain transferability on different datasets. Graph neural networks excel at learning graph data, the omnipresent non-Euclidean structure, but often lack the generalization capacity. Hence, graph foundation model is drawing increasing attention, and recent efforts have been made to leverage Large Language Models. On the one hand, existing studies primarily focus on text-attributed graphs, while a wider range of real graphs do not contain fruitful textual attributes. On the other hand, the sequential graph description tailored for the Large Language Model neglects the structural complexity, which is a predominant characteristic of the graph. Such limitations motivate an important question: Can we go beyond Large Language Models, and pretrain a universal model to learn the structural knowledge for any graph? The answer in the language or vision domain is a shared vocabulary. We observe the fact that there also exist shared substructures underlying graph domain, and thereby open a new opportunity of graph foundation model with structural vocabulary. The key innovation is the discovery of a simple yet effective structural vocabulary of trees and cycles, and we explore its inherent connection to Riemannian geometry. Herein, we present a universal pretraining model, RiemannGFM. Concretely, we first construct a novel product bundle to incorporate the diverse geometries of the vocabulary. Then, on this constructed space, we stack Riemannian layers where the structural vocabulary, regardless of specific graph, is learned in Riemannian manifold offering cross-domain transferability. Extensive experiments show the effectiveness of RiemannGFM on a diversity of real graphs.

cs.LG↗

EncGPT: A Multi-Agent Workflow for Dynamic Encryption Algorithms

Communication encryption is crucial in computer technology, but existing algorithms struggle with balancing cost and security. We propose EncGPT, a multi-agent framework using large language models (LLM). It includes rule, encryption, and decryption agents that generate encryption rules and apply them dynamically. This approach addresses gaps in LLM-based multi-agent systems for communication security. We tested GPT-4o's rule generation and implemented a substitution encryption workflow with homomorphism preservation, achieving an average execution time of 15.99 seconds.

cs.CR↗

Zero-shot Load Forecasting for Integrated Energy Systems: A Large Language Model-based Framework with Multi-task Learning

The growing penetration of renewable energy sources in power systems has increased the complexity and uncertainty of load forecasting, especially for integrated energy systems with multiple energy carriers. Traditional forecasting methods heavily rely on historical data and exhibit limited transferability across different scenarios, posing significant challenges for emerging applications in smart grids and energy internet. This paper proposes the TSLLM-Load Forecasting Mechanism, a novel zero-shot load forecasting framework based on large language models (LLMs) to address these challenges. The framework consists of three key components: a data preprocessing module that handles multi-source energy load data, a time series prompt generation module that bridges the semantic gap between energy data and LLMs through multi-task learning and similarity alignment, and a prediction module that leverages pre-trained LLMs for accurate forecasting. The framework's effectiveness was validated on a real-world dataset comprising load profiles from 20 Australian solar-powered households, demonstrating superior performance in both conventional and zero-shot scenarios. In conventional testing, our method achieved a Mean Squared Error (MSE) of 0.4163 and a Mean Absolute Error (MAE) of 0.3760, outperforming existing approaches by at least 8\%. In zero-shot prediction experiments across 19 households, the framework maintained consistent accuracy with a total MSE of 11.2712 and MAE of 7.6709, showing at least 12\% improvement over current methods. The results validate the framework's potential for accurate and transferable load forecasting in integrated energy systems, particularly beneficial for renewable energy integration and smart grid applications.

cs.LG↗

Optimizing Urban Mobility Through Complex Network Analysis and Big Data from Smart Cards

This study investigates the network characteristics of high-frequency (HF) and low-frequency (LF) travelers in urban public transport systems by analyzing 20 million smart card records from Beijing's transit network. A novel methodology integrates advanced data preprocessing, clustering techniques, and complex network analysis to differentiate HF and LF passenger behaviors and their impacts on network structure, robustness, and efficiency. The primary challenge is accurately segmenting and modeling the behaviors of diverse passenger groups within a large-scale, noisy dataset while maintaining computational efficiency and scalability. HF networks, representing the top 25% of travelers by usage frequency, exhibit high connectivity with an average clustering coefficient of 0.72 and greater node degree centrality. However, they have lower robustness, with efficiency declining by 35% under targeted disruptions and longer average path lengths of 6.2 during peak hours. In contrast, LF networks, which include 75% of travelers, are more dispersed yet resilient, with efficiency declining by only 10% under similar disruptions and stronger intracommunity connectivity. Temporal analysis reveals that HF passengers significantly contribute to peak-hour congestion, with 57.4% of HF trips occurring between 6:00 and 10:00 AM, while LF passengers show a broader temporal distribution, helping to mitigate congestion hotspots. Understanding these travel patterns is crucial for optimizing public transit systems. The findings suggest targeted strategies such as enhancing robustness in HF networks by diversifying key routes and improving accessibility in LF-dominated areas. This research provides a scalable framework for analyzing smart card data and offers actionable insights for optimizing transit networks, improving congestion management, and advancing sustainable urban mobility planning.

cs.SI↗

CLEAR: Cluster-based Prompt Learning on Heterogeneous Graphs

Prompt learning has attracted increasing attention in the graph domain as a means to bridge the gap between pretext and downstream tasks. Existing studies on heterogeneous graph prompting typically use feature prompts to modify node features for specific downstream tasks, which do not concern the structure of heterogeneous graphs. Such a design also overlooks information from the meta-paths, which are core to learning the high-order semantics of the heterogeneous graphs. To address these issues, we propose CLEAR, a Cluster-based prompt LEARNING model on heterogeneous graphs. We present cluster prompts that reformulate downstream tasks as heterogeneous graph reconstruction. In this way, we align the pretext and downstream tasks to share the same training objective. Additionally, our cluster prompts are also injected into the meta-paths such that the prompt learning process incorporates high-order semantic information entailed by the meta-paths. Extensive experiments on downstream tasks confirm the superiority of CLEAR. It consistently outperforms state-of-the-art models, achieving up to 5% improvement on the F1 metric for node classification.

cs.LG↗

Motion Forecasting for Autonomous Vehicles: A Survey

In recent years, the field of autonomous driving has attracted increasingly significant public interest. Accurately forecasting the future behavior of various traffic participants is essential for the decision-making of Autonomous Vehicles (AVs). In this paper, we focus on both scenario-based and perception-based motion forecasting for AVs. We propose a formal problem formulation for motion forecasting and summarize the main challenges confronting this area of research. We also detail representative datasets and evaluation metrics pertinent to this field. Furthermore, this study classifies recent research into two main categories: supervised learning and self-supervised learning, reflecting the evolving paradigms in both scenario-based and perception-based motion forecasting. In the context of supervised learning, we thoroughly examine and analyze each key element of the methodology. For self-supervised learning, we summarize commonly adopted techniques. The paper concludes and discusses potential research directions, aiming to propel progress in this vital area of AV technology.

cs.RO↗