arXiv subjects

Li-Chin Chen

Publications and source records attributed to Li-Chin Chen.

2 recordsLinked to original sources

arXiv2026

Deep denoising autoencoder-based non-invasive blood flow detection for arteriovenous fistula

Clinical guidelines underscore the importance of regularly monitoring and surveilling arteriovenous fistula (AVF) access in hemodialysis patients to promptly detect any dysfunction. Although phono-angiography/sound analysis overcomes the limitations of standardized AVF stenosis diagnosis tool, prior studies have depended on conventional feature extraction methods, restricting their applicability in diverse contexts. In contrast, representation learning captures fundamental underlying factors that can be readily transferred across different contexts. We propose an approach based on deep denoising autoencoders (DAEs) that perform dimensionality reduction and reconstruction tasks using the waveform obtained through one-level discrete wavelet transform, utilizing representation learning. Our results demonstrate that the latent representation generated by the DAE surpasses expectations with an accuracy of 0.93. The incorporation of noise-mixing and the utilization of a noise-to-clean scheme effectively enhance the discriminative capabilities of the latent representation. Moreover, when employed to identify patient-specific characteristics, the latent representation exhibited performance by surpassing an accuracy of 0.92. Appropriate light-weighted methods can restore the detection performance of the excessively reduced dimensionality version and enable operation on less computational devices. Our findings suggest that representation learning is a more feasible approach for extracting auscultation features in AVF, leading to improved generalization and applicability across multiple tasks. The manipulation of latent representations holds immense potential for future advancements. Further investigations in this area are promising and warrant continued exploration.

cs.LG↗

arXiv2026

General Demographic Pre-trained Models for Enhancing Predictive Performance Across Diseases and Population

Foundation models for healthcare require balancing robust generalization across heterogeneous clinical populations and disease settings with the architectural simplicity needed for deployment. We present a pre-trained model focused on demographic attributes that enhances feature utility across medical domains in a plug-and-play fashion. We introduce the General Demographic Pre-trained (GDP) model, designed to extract intrinsic representations of patient status based on age and sex, the two most ubiquitous clinical features. The composition of GDP was optimized by investigating various encoding methods and visit-reordering schemes. The model was pre-trained and transferability was validated by embedding the learned representations into diverse disease and geographic cohorts characterized by distinct demographic profiles. The optimal model configuration was subsequently validated against top-performing tabular foundation models (TabPFN, TabICL, and TabFM). Our findings demonstrate that concatenating GDP-derived embeddings with raw residual features consistently enhances predictive performance across classification tasks while elevating the relative importance of demographic attributes. The embedding transformation provides superior representational separability compared to the original data distribution, yielding competitive discrimination performance across metrics against all three general-purpose foundation models and tree-based algorithm. GDP has successfully served the purpose of a foundation model, which produce enriched representations that amplify the predictive insight of these features beyond their raw form. The generated embeddings can be directly concatenated with residual features, serving as an enhancement layer that maintains full compatibility with standard tabular classifiers.

cs.LG↗