arXiv subjects

Licong Dong

Publications and source records attributed to Licong Dong.

3 recordsLinked to original sources

arXiv2026

Preoperative Prediction of Microvascular Invasion in Hepatocellular Carcinoma by Integrating Multimodal Ultrasound and Clinical Data: A Multicenter Study

Background: Microvascular invasion (MVI) predicts recurrence and survival in hepatocellular carcinoma (HCC) but requires postoperative histopathology for diagnosis. We developed and validated a model integrating multimodal ultrasound and clinical data for preoperative MVI prediction. Methods: This multicenter study included 489 patients with HCC from eight centers. All patients had B-mode ultrasound (BUS), color Doppler flow imaging (CDFI), dynamic contrast-enhanced ultrasound (DCE-US), and clinical information. Data from seven centers (n = 421) were used for model development with five-fold cross-validation; data from the remaining center (n = 68) formed an independent external validation cohort. The proposed multimodal information fusion network used modality-specific encoders, a hemodynamic temporal change module for bidirectional DCE-US perfusion changes, and a representation consistency learning module to align heterogeneous ultrasound representations before Transformer-based fusion. Results: In external validation, DCE-US achieved the highest single-modality area under the receiver operating characteristic curve (AUC; 0.8545+/-0.0198), versus clinical information (0.6715+/-0.0156), CDFI (0.6435+/-0.0344), and BUS (0.6087+/-0.0417). Pixel-difference sampling and the proposed temporal module outperformed alternative sampling and video representation methods. The full model achieved the best performance, with an AUC of 0.8953+/-0.0180, accuracy of 81.18%+/-2.83%, sensitivity of 86.40%+/-6.69%, and specificity of 78.14%+/-6.28. Conclusions: Integrating multimodal ultrasound and clinical information enabled promising preoperative MVI prediction in HCC. DCE-US was the main source of predictive information, while BUS, CDFI, and clinical information provided complementary value. The proposed framework may support preoperative risk stratification and individualized clinical decision-making.

cs.CV↗

arXiv2022

Soft-CP: A Credible and Effective Data Augmentation for Semantic Segmentation of Medical Lesions

The medical datasets are usually faced with the problem of scarcity and data imbalance. Moreover, annotating large datasets for semantic segmentation of medical lesions is domain-knowledge and time-consuming. In this paper, we propose a new object-blend method(short in soft-CP) that combines the Copy-Paste augmentation method for semantic segmentation of medical lesions offline, ensuring the correct edge information around the lession to solve the issue above-mentioned. We proved the method's validity with several datasets in different imaging modalities. In our experiments on the KiTS19[2] dataset, Soft-CP outperforms existing medical lesions synthesis approaches. The Soft-CP augementation provides gains of +26.5% DSC in the low data regime(10% of data) and +10.2% DSC in the high data regime(all of data), In offline training data, the ratio of real images to synthetic images is 3:1.

eess.IV↗

arXiv2021

More Reliable AI Solution: Breast Ultrasound Diagnosis Using Multi-AI Combination

Objective: Breast cancer screening is of great significance in contemporary women's health prevention. The existing machines embedded in the AI system do not reach the accuracy that clinicians hope. How to make intelligent systems more reliable is a common problem. Methods: 1) Ultrasound image super-resolution: the SRGAN super-resolution network reduces the unclearness of ultrasound images caused by the device itself and improves the accuracy and generalization of the detection model. 2) In response to the needs of medical images, we have improved the YOLOv4 and the CenterNet models. 3) Multi-AI model: based on the respective advantages of different AI models, we employ two AI models to determine clinical resuls cross validation. And we accept the same results and refuses others. Results: 1) With the help of the super-resolution model, the YOLOv4 model and the CenterNet model both increased the mAP score by 9.6% and 13.8%. 2) Two methods for transforming the target model into a classification model are proposed. And the unified output is in a specified format to facilitate the call of the molti-AI model. 3) In the classification evaluation experiment, concatenated by the YOLOv4 model (sensitivity 57.73%, specificity 90.08%) and the CenterNet model (sensitivity 62.64%, specificity 92.54%), the multi-AI model will refuse to make judgments on 23.55% of the input data. Correspondingly, the performance has been greatly improved to 95.91% for the sensitivity and 96.02% for the specificity. Conclusion: Our work makes the AI model more reliable in medical image diagnosis. Significance: 1) The proposed method makes the target detection model more suitable for diagnosing breast ultrasound images. 2) It provides a new idea for artificial intelligence in medical diagnosis, which can more conveniently introduce target detection models from other fields to serve medical lesion screening.

cs.CV↗