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Lin Gu

Publications and source records attributed to Lin Gu.

At least 37 records · Page 2Linked to original sources

From edges to meaning: Semantic line sketches as a cognitive scaffold for ancient pictograph invention

Humans readily recognize objects from sparse line drawings, a capacity that appears early in development and persists across cultures, suggesting neural rather than purely learned origins. Yet the computational mechanism by which the brain transforms high-level semantic knowledge into low-level visual symbols remains poorly understood. Here we propose that ancient pictographic writing emerged from the brain's intrinsic tendency to compress visual input into stable, boundary-based abstractions. We construct a biologically inspired digital twin of the visual hierarchy that encodes an image into low-level features, generates a contour sketch, and iteratively refines it through top-down feedback guided by semantic representations, mirroring the feedforward and recurrent architecture of the human visual cortex. The resulting symbols bear striking structural resemblance to early pictographs across culturally distant writing systems, including Egyptian hieroglyphs, Chinese oracle bone characters, and proto-cuneiform, and offer candidate interpretations for undeciphered scripts. Our findings support a neuro-computational origin of pictographic writing and establish a framework in which AI can recapitulate the cognitive processes by which humans first externalized perception into symbols.

cs.AI↗

Fourier Angle Alignment for Oriented Object Detection in Remote Sensing

In remote sensing rotated object detection, mainstream methods suffer from two bottlenecks, directional incoherence at detector neck and task conflict at detecting head. Ulitising fourier rotation equivariance, we introduce Fourier Angle Alignment, which analyses angle information through frequency spectrum and aligns the main direction to a certain orientation. Then we propose two plug and play modules : FAAFusion and FAA Head. FAAFusion works at the detector neck, aligning the main direction of higher-level features to the lower-level features and then fusing them. FAA Head serves as a new detection head, which pre-aligns RoI features to a canonical angle and adds them to the original features before classification and regression. Experiments on DOTA-v1.0, DOTA-v1.5 and HRSC2016 show that our method can greatly improve previous work. Particularly, our method achieves new state-of-the-art results of 78.72% mAP on DOTA-v1.0 and 72.28% mAP on DOTA-v1.5 datasets with single scale training and testing, validating the efficacy of our approach in remote sensing object detection. The code is made publicly available at https://github.com/gcy0423/Fourier-Angle-Alignment .

cs.CV↗

SGI: Structured 2D Gaussians for Efficient and Compact Large Image Representation

2D Gaussian Splatting has emerged as a novel image representation technique that can support efficient rendering on low-end devices. However, scaling to high-resolution images requires optimizing and storing millions of unstructured Gaussian primitives independently, leading to slow convergence and redundant parameters. To address this, we propose Structured Gaussian Image (SGI), a compact and efficient framework for representing high-resolution images. SGI decomposes a complex image into multi-scale local spaces defined by a set of seeds. Each seed corresponds to a spatially coherent region and, together with lightweight multi-layer perceptrons (MLPs), generates structured implicit 2D neural Gaussians. This seed-based formulation imposes structural regularity on otherwise unstructured Gaussian primitives, which facilitates entropy-based compression at the seed level to reduce the total storage. However, optimizing seed parameters directly on high-resolution images is a challenging and non-trivial task. Therefore, we designed a multi-scale fitting strategy that refines the seed representation in a coarse-to-fine manner, substantially accelerating convergence. Quantitative and qualitative evaluations demonstrate that SGI achieves up to 7.5x compression over prior non-quantized 2D Gaussian methods and 1.6x over quantized ones, while also delivering 1.6x and 6.5x faster optimization, respectively, without degrading, and often improving, image fidelity. Code is available at https://github.com/zx-pan/SGI.

cs.CV↗

Unifying Color and Lightness Correction with View-Adaptive Curve Adjustment for Robust 3D Novel View Synthesis

High-quality image acquisition in real-world environments remains challenging due to complex illumination variations and inherent limitations of camera imaging pipelines. These issues are exacerbated in multi-view capture, where differences in lighting, sensor responses, and image signal processor (ISP) configurations introduce photometric and chromatic inconsistencies that violate the assumptions of photometric consistency underlying modern 3D novel view synthesis (NVS) methods, including Neural Radiance Fields (NeRF) and 3D Gaussian Splatting (3DGS), leading to degraded reconstruction and rendering quality. We propose Luminance-GS++, a 3DGS-based framework for robust NVS under diverse illumination conditions. Our method combines a globally view-adaptive lightness adjustment with a local pixel-wise residual refinement for precise color correction. We further design unsupervised objectives that jointly enforce lightness correction and multi-view geometric and photometric consistency. Extensive experiments demonstrate state-of-the-art performance across challenging scenarios, including low-light, overexposure, and complex luminance and chromatic variations. Unlike prior approaches that modify the underlying representation, our method preserves the explicit 3DGS formulation, improving reconstruction fidelity while maintaining real-time rendering efficiency.

cs.CV↗

Topological Semimetal Transport Modulated by Interstitial Fe in Ba(Fe$_{1-x}$Co$_x$)$_{2+δ}As$_2$ Superconductors

Topological semimetals are renowned for exhibiting large, unsaturated magnetoresistance arising from ultrahigh carrier mobility and electron-hole compensation. However, such behaviors remain poorly understood in iron-based superconductors that have been recently recognized to harbor rich nontrivial topology. Here, we combine angle-resolved magneto-transport measurements with first principles calculations to reveal the emergence and tunability of topological semimetals in ferropnictide Ba(Fe$_{1-x}$Co$_x$)$_{2+δ}As$_2$ epitaxial films, modulated by interstitial Fe. These states exhibit ultralow residual resistivity, coexisting high-mobility electron and hole carriers, and linear positive magnetoresistance below 110 K. Remarkably, the magnetoresistance becomes more pronounced when the magnetic field is applied parallel to the film plane, reaching an unsaturated 1206% at 56 T. Furthermore, superconductivity persists in these ferropnictide films, establishing them as a tunable platform for investigating the interplay among electron correlation, topology, and superconductivity.

cond-mat.supr-con↗

RealX3D: A Physically-Degraded 3D Benchmark for Multi-view Visual Restoration and Reconstruction

We introduce RealX3D, a real-capture benchmark for multi-view visual restoration and 3D reconstruction under diverse physical degradations. RealX3D groups corruptions into four families, including illumination, scattering, occlusion, and blurring, and captures each at multiple severity levels using a unified acquisition protocol that yields pixel-aligned LQ/GT views. Each scene includes high-resolution capture, RAW images, and dense laser scans, from which we derive world-scale meshes and metric depth. Benchmarking a broad range of optimization-based and feed-forward methods shows substantial degradation in reconstruction quality under physical corruptions, underscoring the fragility of current multi-view pipelines in real-world challenging environments.

cs.CV↗

Large-scale EM Benchmark for Multi-Organelle Instance Segmentation in the Wild

Accurate instance-level segmentation of organelles in electron microscopy (EM) is critical for quantitative analysis of subcellular morphology and inter-organelle interactions. However, current benchmarks, based on small, curated datasets, fail to capture the inherent heterogeneity and large spatial context of in-the-wild EM data, imposing fundamental limitations on current patch-based methods. To address these limitations, we developed a large-scale, multi-source benchmark for multi-organelle instance segmentation, comprising over 100,000 2D EM images across variety cell types and five organelle classes that capture real-world variability. Dataset annotations were generated by our designed connectivity-aware Label Propagation Algorithm (3D LPA) with expert refinement. We further benchmarked several state-of-the-art models, including U-Net, SAM variants, and Mask2Former. Our results show several limitations: current models struggle to generalize across heterogeneous EM data and perform poorly on organelles with global, distributed morphologies (e.g., Endoplasmic Reticulum). These findings underscore the fundamental mismatch between local-context models and the challenge of modeling long-range structural continuity in the presence of real-world variability. The benchmark dataset and labeling tool will be publicly released soon.

cs.CV↗

AutoBinder Agent: An MCP-Based Agent for End-to-End Protein Binder Design

Modern AI technologies for drug discovery are distributed across heterogeneous platforms-including web applications, desktop environments, and code libraries-leading to fragmented workflows, inconsistent interfaces, and high integration overhead. We present an agentic end-to-end drug design framework that leverages a Large Language Model (LLM) in conjunction with the Model Context Protocol (MCP) to dynamically coordinate access to biochemical databases, modular toolchains, and task-specific AI models. The system integrates four state-of-the-art components: MaSIF (MaSIF-site and MaSIF-seed-search) for geometric deep learning-based identification of protein-protein interaction (PPI) sites, Rosetta for grafting protein fragments onto protein backbones to form mini proteins, ProteinMPNN for amino acid sequences redesign, and AlphaFold3 for near-experimental accuracy in complex structure prediction. Starting from a target structure, the framework supports de novo binder generation via surface analysis, scaffold grafting and pose construction, sequence optimization, and structure prediction. Additionally, by replacing rigid, script-based workflows with a protocol-driven, LLM-coordinated architecture, the framework improves reproducibility, reduces manual overhead, and ensures extensibility, portability, and auditability across the entire drug design process.

q-bio.BM↗

RFAssigner: A Generic Label Assignment Strategy for Dense Object Detection

Label assignment is a critical component in training dense object detectors. State-of-the-art methods typically assign each training sample a positive and a negative weight, optimizing the assignment scheme during training. However, these strategies often assign an insufficient number of positive samples to small objects, leading to a scale imbalance during training. To address this limitation, we introduce RFAssigner, a novel assignment strategy designed to enhance the multi-scale learning capabilities of dense detectors. RFAssigner first establishes an initial set of positive samples using a point-based prior. It then leverages a Gaussian Receptive Field (GRF) distance to measure the similarity between the GRFs of unassigned candidate locations and the ground-truth objects. Based on this metric, RFAssigner adaptively selects supplementary positive samples from the unassigned pool, promoting a more balanced learning process across object scales. Comprehensive experiments on three datasets with distinct object scale distributions validate the effectiveness and generalizability of our method. Notably, a single FCOS-ResNet-50 detector equipped with RFAssigner achieves state-of-the-art performance across all object scales, consistently outperforming existing strategies without requiring auxiliary modules or heuristics.

cs.CV↗

Perception-Inspired Color Space Design for Photo White Balance Editing

White balance (WB) is a key step in the image signal processor (ISP) pipeline that mitigates color casts caused by varying illumination and restores the scene's true colors. Currently, sRGB-based WB editing for post-ISP WB correction is widely used to address color constancy failures in the ISP pipeline when the original camera RAW is unavailable. However, additive color models (e.g., sRGB) are inherently limited by fixed nonlinear transformations and entangled color channels, which often impede their generalization to complex lighting conditions. To address these challenges, we propose a novel framework for WB correction that leverages a perception-inspired Learnable HSI (LHSI) color space. Built upon a cylindrical color model that naturally separates luminance from chromatic components, our framework further introduces dedicated parameters to enhance this disentanglement and learnable mapping to adaptively refine the flexibility. Moreover, a new Mamba-based network is introduced, which is tailored to the characteristics of the proposed LHSI color space. Experimental results on benchmark datasets demonstrate the superiority of our method, highlighting the potential of perception-inspired color space design in computational photography. The source code is available at https://github.com/YangCheng58/WB_Color_Space.

cs.CV↗

Rep-GLS: Report-Guided Generalized Label Smoothing for Robust Disease Detection

Unlike nature image classification where groundtruth label is explicit and of no doubt, physicians commonly interpret medical image conditioned on certainty like using phrase "probable" or "likely". Existing medical image datasets either simply overlooked the nuance and polarise into binary label. Here, we propose a novel framework that leverages a Large Language Model (LLM) to directly mine medical reports to utilise the uncertainty relevant expression for supervision signal. At first, we collect uncertainty keywords from medical reports. Then, we use Qwen-3 4B to identify the textual uncertainty and map them into an adaptive Generalized Label Smoothing (GLS) rate. This rate allows our model to treat uncertain labels not as errors, but as informative signals, effectively incorporating expert skepticism into the training process. We establish a new clinical expert uncertainty-aware benchmark to rigorously evaluate this problem. Experiments demonstrate that our approach significantly outperforms state-of-the-art methods in medical disease detection. The curated uncertainty words database, code, and benchmark will be made publicly available upon acceptance.

cs.LG↗

GeoSVR: Taming Sparse Voxels for Geometrically Accurate Surface Reconstruction

Reconstructing accurate surfaces with radiance fields has achieved remarkable progress in recent years. However, prevailing approaches, primarily based on Gaussian Splatting, are increasingly constrained by representational bottlenecks. In this paper, we introduce GeoSVR, an explicit voxel-based framework that explores and extends the under-investigated potential of sparse voxels for achieving accurate, detailed, and complete surface reconstruction. As strengths, sparse voxels support preserving the coverage completeness and geometric clarity, while corresponding challenges also arise from absent scene constraints and locality in surface refinement. To ensure correct scene convergence, we first propose a Voxel-Uncertainty Depth Constraint that maximizes the effect of monocular depth cues while presenting a voxel-oriented uncertainty to avoid quality degradation, enabling effective and robust scene constraints yet preserving highly accurate geometries. Subsequently, Sparse Voxel Surface Regularization is designed to enhance geometric consistency for tiny voxels and facilitate the voxel-based formation of sharp and accurate surfaces. Extensive experiments demonstrate our superior performance compared to existing methods across diverse challenging scenarios, excelling in geometric accuracy, detail preservation, and reconstruction completeness while maintaining high efficiency. Code is available at https://github.com/Fictionarry/GeoSVR.

cs.CV↗

I2-NeRF: Learning Neural Radiance Fields Under Physically-Grounded Media Interactions

Participating in efforts to endow generative AI with the 3D physical world perception, we propose I2-NeRF, a novel neural radiance field framework that enhances isometric and isotropic metric perception under media degradation. While existing NeRF models predominantly rely on object-centric sampling, I2-NeRF introduces a reverse-stratified upsampling strategy to achieve near-uniform sampling across 3D space, thereby preserving isometry. We further present a general radiative formulation for media degradation that unifies emission, absorption, and scattering into a particle model governed by the Beer-Lambert attenuation law. By composing the direct and media-induced in-scatter radiance, this formulation extends naturally to complex media environments such as underwater, haze, and even low-light scenes. By treating light propagation uniformly in both vertical and horizontal directions, I2-NeRF enables isotropic metric perception and can even estimate medium properties such as water depth. Experiments on real-world datasets demonstrate that our method significantly improves both reconstruction fidelity and physical plausibility compared to existing approaches.

cs.CV↗

Frequency-Dynamic Attention Modulation for Dense Prediction

Vision Transformers (ViTs) have significantly advanced computer vision, demonstrating strong performance across various tasks. However, the attention mechanism in ViTs makes each layer function as a low-pass filter, and the stacked-layer architecture in existing transformers suffers from frequency vanishing. This leads to the loss of critical details and textures. We propose a novel, circuit-theory-inspired strategy called Frequency-Dynamic Attention Modulation (FDAM), which can be easily plugged into ViTs. FDAM directly modulates the overall frequency response of ViTs and consists of two techniques: Attention Inversion (AttInv) and Frequency Dynamic Scaling (FreqScale). Since circuit theory uses low-pass filters as fundamental elements, we introduce AttInv, a method that generates complementary high-pass filtering by inverting the low-pass filter in the attention matrix, and dynamically combining the two. We further design FreqScale to weight different frequency components for fine-grained adjustments to the target response function. Through feature similarity analysis and effective rank evaluation, we demonstrate that our approach avoids representation collapse, leading to consistent performance improvements across various models, including SegFormer, DeiT, and MaskDINO. These improvements are evident in tasks such as semantic segmentation, object detection, and instance segmentation. Additionally, we apply our method to remote sensing detection, achieving state-of-the-art results in single-scale settings. The code is available at https://github.com/Linwei-Chen/FDAM.

cs.CV↗

EGTM: Event-guided Efficient Turbulence Mitigation

Turbulence mitigation (TM) aims to remove the stochastic distortions and blurs introduced by atmospheric turbulence into frame cameras. Existing state-of-the-art deep-learning TM methods extract turbulence cues from multiple degraded frames to find the so-called "lucky'', not distorted patch, for "lucky fusion''. However, it requires high-capacity network to learn from coarse-grained turbulence dynamics between synchronous frames with limited frame-rate, thus fall short in computational and storage efficiency. Event cameras, with microsecond-level temporal resolution, have the potential to fundamentally address this bottleneck with efficient sparse and asynchronous imaging mechanism. In light of this, we (i) present the fundamental \textbf{``event-lucky insight''} to reveal the correlation between turbulence distortions and inverse spatiotemporal distribution of event streams. Then, build upon this insight, we (ii) propose a novel EGTM framework that extracts pixel-level reliable turbulence-free guidance from the explicit but noisy turbulent events for temporal lucky fusion. Moreover, we (iii) build the first turbulence data acquisition system to contribute the first real-world event-driven TM dataset. Extensive experimental results demonstrate that our approach significantly surpass the existing SOTA TM method by 710 times, 214 times and 224 times in model size, inference latency and model complexity respectively, while achieving the state-of-the-art in restoration quality (+0.94 PSNR and +0.08 SSIM) on our real-world EGTM dataset. This demonstrating the great efficiency merit of introducing event modality into TM task. Demo code and data have been uploaded in supplementary material and will be released once accepted.

cs.CV↗

Association of Timing and Duration of Moderate-to-Vigorous Physical Activity with Cognitive Function and Brain Aging: A Population-Based Study Using the UK Biobank

Physical activity is a modifiable lifestyle factor with potential to support cognitive resilience. However, the association of moderate-to-vigorous physical activity (MVPA) intensity, and timing, with cognitive function and region-specific brain structure remain poorly understood. We analyzed data from 45,892 UK Biobank participants aged 60 years and older with valid wrist-worn accelerometer data, cognitive testing, and structural brain MRI. MVPA was measured both continuously (mins per week) and categorically (thresholded using >=150 min/week based on WHO guidelines). Associations with cognitive performance and regional brain volumes were evaluated using multivariable linear models adjusted for demographic, socioeconomic, and health-related covariates. We conducted secondary analyses on MVPA timing and subgroup effects. Higher MVPA was associated with better performance across cognitive domains, including reasoning, memory, executive function, and processing speed. These associations persisted in fully adjusted models and were higher among participants meeting WHO guidelines. Greater MVPA was also associated with subcortical brain regions (caudate, putamen, pallidum, thalamus), as well as regional gray matter volumes involved in emotion, working memory, and perceptual processing. Secondary analyses showed that MVPA at any time of day was associated with cognitive functions and brain volume particularly in the midday-afternoon and evening. Sensitivity analysis shows consistent findings across subgroups, with evidence of dose-response relationships. Higher MVPA is associated with preserved brain structure and enhanced cognitive function in later life. Public health strategies to increase MVPA may support healthy cognitive aging and generate substantial economic benefits, with global gains projected to reach USD 760 billion annually by 2050.

q-bio.NC↗

Computation-Efficient and Recognition-Friendly 3D Point Cloud Privacy Protection

3D point cloud has been widely used in applications such as self-driving cars, robotics, CAD models, etc. To the best of our knowledge, these applications raised the issue of privacy leakage in 3D point clouds, which has not been studied well. Different from the 2D image privacy, which is related to texture and 2D geometric structure, the 3D point cloud is texture-less and only relevant to 3D geometric structure. In this work, we defined the 3D point cloud privacy problem and proposed an efficient privacy-preserving framework named PointFlowGMM that can support downstream classification and segmentation tasks without seeing the original data. Using a flow-based generative model, the point cloud is projected into a latent Gaussian mixture distributed subspace. We further designed a novel angular similarity loss to obfuscate the original geometric structure and reduce the model size from 767MB to 120MB without a decrease in recognition performance. The projected point cloud in the latent space is orthogonally rotated randomly to further protect the original geometric structure, the class-to-class relationship is preserved after rotation, thus, the protected point cloud can support the recognition task. We evaluated our model on multiple datasets and achieved comparable recognition results on encrypted point clouds compared to the original point clouds.

cs.CV↗

Interstitial oxygen order and its competition with superconductivity in La$_2$PrNi$_2$O$_{7+δ}$

High-temperature superconductivity in bilayer nickelate La$_3$Ni$_2$O$_7$ under pressure has attracted significant interest in condensed matter physics. While early samples exhibited limited superconducting volume fractions, Pr substitution for La enabled bulk superconductivity in polycrystals under pressure and enhanced transition temperatures in thin films at ambient pressure. Beyond rare-earth doping, moderate oxygen or ozone annealing improves superconductivity by mitigating oxygen vacancies, whereas high-pressure oxygen annealing leads to a trivial, non-superconducting metallic state across all pressure regimes. These findings highlight the need to elucidate both the individual and combined effects of Pr doping and oxygen stoichiometry in modulating superconductivity in bilayer nickelates. Here, using multislice electron ptychography and electron energy-loss spectroscopy, we investigate the structural and electronic properties of as-grown La$_2$PrNi$_2$O$_7$ and high-pressure-oxygen-annealed La$_2$PrNi$_2$O$_{7+δ}$ polycrystals. We find that Pr dopants preferentially occupy outer La sites, effectively eliminating inner-apical oxygen vacancies and ensuring near-stoichiometry in as-grown La$_2$PrNi$_2$O$_7$ that is bulk-superconducting under pressure. In contrast, high-pressure oxygen annealing induces a striped interstitial oxygen order, introducing quasi-1D lattice potentials and excess hole carriers into p-d hybridized orbitals, ultimately suppressing superconductivity. This behavior starkly contrasts with cuprate superconductors, where similar interstitial oxygen ordering enhances superconductivity instead. Our findings reveal a competition between striped interstitial oxygen order and superconductivity in bilayer nickelates, offering key insights into their distinct pairing mechanisms and providing a roadmap for designing more robust superconducting phases.

cond-mat.supr-con↗