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Lu Zhang

Publications and source records attributed to Lu Zhang.

At least 307 records · Page 17Linked to original sources

Disease2Vec: Representing Alzheimer's Progression via Disease Embedding Tree

For decades, a variety of predictive approaches have been proposed and evaluated in terms of their prediction capability for Alzheimer's Disease (AD) and its precursor - mild cognitive impairment (MCI). Most of them focused on prediction or identification of statistical differences among different clinical groups or phases (e.g., longitudinal studies). The continuous nature of AD development and transition states between successive AD related stages have been overlooked, especially in binary or multi-class classification. Though a few progression models of AD have been studied recently, they were mainly designed to determine and compare the order of specific biomarkers. How to effectively predict the individual patient's status within a wide spectrum of continuous AD progression has been largely overlooked. In this work, we developed a novel learning-based embedding framework to encode the intrinsic relations among AD related clinical stages by a set of meaningful embedding vectors in the latent space (Disease2Vec). We named this process as disease embedding. By disease em-bedding, the framework generates a disease embedding tree (DETree) which effectively represents different clinical stages as a tree trajectory reflecting AD progression and thus can be used to predict clinical status by projecting individuals onto this continuous trajectory. Through this model, DETree can not only perform efficient and accurate prediction for patients at any stages of AD development (across five clinical groups instead of typical two groups), but also provide richer status information by examining the projecting locations within a wide and continuous AD progression process.

q-bio.NC↗

Objective quality assessment of medical images and videos: Review and challenges

Quality assessment is a key element for the evaluation of hardware and software involved in image and video acquisition, processing, and visualization. In the medical field, user-based quality assessment is still considered more reliable than objective methods, which allow the implementation of automated and more efficient solutions. Regardless of increasing research in this topic in the last decade, defining quality standards for medical content remains a non-trivial task, as the focus should be on the diagnostic value assessed from expert viewers rather than the perceived quality from naïve viewers, and objective quality metrics should aim at estimating the first rather than the latter. In this paper, we present a survey of methodologies used for the objective quality assessment of medical images and videos, dividing them into visual quality-based and task-based approaches. Visual quality based methods compute a quality index directly from visual attributes, while task-based methods, being increasingly explored, measure the impact of quality impairments on the performance of a specific task. A discussion on the limitations of state-of-the-art research on this topic is also provided, along with future challenges to be addressed.

eess.IV↗

Test Flakiness' Causes, Detection, Impact and Responses: A Multivocal Review

Flaky tests (tests with non-deterministic outcomes) pose a major challenge for software testing. They are known to cause significant issues such as reducing the effectiveness and efficiency of testing and delaying software releases. In recent years, there has been an increased interest in flaky tests, with research focusing on different aspects of flakiness, such as identifying causes, detection methods and mitigation strategies. Test flakiness has also become a key discussion point for practitioners (in blog posts, technical magazines, etc.) as the impact of flaky tests is felt across the industry. This paper presents a multivocal review that investigates how flaky tests, as a topic, have been addressed in both research and practice. We cover a total of 651 articles (560 academic articles and 91 grey literature articles/posts), and structure the body of relevant research and knowledge using four different dimensions: causes, detection, impact and responses. For each of those dimensions we provide a categorisation, and classify existing research, discussions, methods and tools. With this, we provide a comprehensive and current snapshot of existing thinking on test flakiness, covering both academic views and industrial practices, and identify limitations and opportunities for future research.

cs.SE↗

Metadata Caching in Presto: Towards Fast Data Processing

Presto is an open-source distributed SQL query engine for OLAP, aiming for "SQL on everything". Since open-sourced in 2013, Presto has been consistently gaining popularity in large-scale data analytics and attracting adoption from a wide range of enterprises. From the development and operation of Presto, we witnessed a significant amount of CPU consumption on parsing column-oriented data files in Presto worker nodes. This blocks some companies, including Meta, from increasing analytical data volumes. In this paper, we present a metadata caching layer, built on top of the Alluxio SDK cache and incorporated in each Presto worker node, to cache the intermediate results in file parsing. The metadata cache provides two caching methods: caching the decompressed metadata bytes from raw data files and caching the deserialized metadata objects. Our evaluation of the TPC-DS benchmark on Presto demonstrates that when the cache is warm, the first method can reduce the query's CPU consumption by 10%-20%, whereas the second method can minimize the CPU usage by 20%-40%.

cs.DB↗

Generalized weighted number operators on functionals of discrete-time normal martingales

Let $M$ be a discrete-time normal martingale that has the chaotic representation property. Then, from the space of square integrable functionals of $M$, one can construct generalized functionals of $M$. In this paper, by using a type of weights, we introduce a class of continuous linear operators acting on generalized functionals of $M$, which we call generalized weighted number (GWN) operators. We prove that GWN operators can be represented in terms of generalized annihilation and creation operators (acting on generalized functionals of $M$). We also examine commutation relations between a GWN operator and a generalized annihilation (or creation) operator, and obtain several formulas expressing such commutation relations.

math.PR↗

Generating Textual Adversaries with Minimal Perturbation

Many word-level adversarial attack approaches for textual data have been proposed in recent studies. However, due to the massive search space consisting of combinations of candidate words, the existing approaches face the problem of preserving the semantics of texts when crafting adversarial counterparts. In this paper, we develop a novel attack strategy to find adversarial texts with high similarity to the original texts while introducing minimal perturbation. The rationale is that we expect the adversarial texts with small perturbation can better preserve the semantic meaning of original texts. Experiments show that, compared with state-of-the-art attack approaches, our approach achieves higher success rates and lower perturbation rates in four benchmark datasets.

cs.CL↗

Investigation of the Pauli paramagnetic effect in systematically tuned NbN thin films

Superconductivity and the normal-state properties of NbN films can be tuned in a wide range, supplying a suitable platform to investigate the systematical evolution of the superconducting performances. Herein, we report the upper critical field of NbN films in both the vertical ($B\perp$ film) and parallel ($B\parallel$ film) orientations over a wide temperature range. Eight samples with the superconducting critical temperature $T_c$ ranging from 2.5 K to 9.8 K are studied. Meanwhile, the normal-state resistivity is tuned by more than six times by changing the conditions of the film growth. It is found that the magnitudes of the upper critical field in both field directions ($B_{c2}^{\perp}$ and $B_{c2}^{\parallel}$) exceed the paramagnetic limiting field $B_p$. The temperature dependent $B_{c2}^{\perp}$ can be described by the extended Werthamer--Helfand--Hohenberg (WHH) model considering the Pauli spin paramagnetism. Meanwhile, the $B_{c2}^{\parallel}$-$T$ data shows the feature of two-dimensional superconductivity in the temperature range near $T_c$. The evolution of the obtained Maki parameter with other parameters, such as the slope of the upper critical field near $T_c$ and the normal-state resistivity, are discussed to reveal the characteristics of the Pauli paramagnetic effect in this system.

cond-mat.supr-con↗

Towards edible drones for rescue missions: design and flight of nutritional wings

Drones have shown to be useful aerial vehicles for unmanned transport missions such as food and medical supply delivery. This can be leveraged to deliver life-saving nutrition and medicine for people in emergency situations. However, commercial drones can generally only carry 10 % - 30 % of their own mass as payload, which limits the amount of food delivery in a single flight. One novel solution to noticeably increase the food-carrying ratio of a drone, is recreating some structures of a drone, such as the wings, with edible materials. We thus propose a drone, which is no longer only a food transporting aircraft, but itself is partially edible, increasing its food-carrying mass ratio to 50 %, owing to its edible wings. Furthermore, should the edible drone be left behind in the environment after performing its task in an emergency situation, it will be more biodegradable than its non-edible counterpart, leaving less waste in the environment. Here we describe the choice of materials and scalable design of edible wings, and validate the method in a flight-capable prototype that can provide 300 kcal and carry a payload of 80 g of water.

cs.RO↗

ISA-Net: Improved spatial attention network for PET-CT tumor segmentation

Achieving accurate and automated tumor segmentation plays an important role in both clinical practice and radiomics research. Segmentation in medicine is now often performed manually by experts, which is a laborious, expensive and error-prone task. Manual annotation relies heavily on the experience and knowledge of these experts. In addition, there is much intra- and interobserver variation. Therefore, it is of great significance to develop a method that can automatically segment tumor target regions. In this paper, we propose a deep learning segmentation method based on multimodal positron emission tomography-computed tomography (PET-CT), which combines the high sensitivity of PET and the precise anatomical information of CT. We design an improved spatial attention network(ISA-Net) to increase the accuracy of PET or CT in detecting tumors, which uses multi-scale convolution operation to extract feature information and can highlight the tumor region location information and suppress the non-tumor region location information. In addition, our network uses dual-channel inputs in the coding stage and fuses them in the decoding stage, which can take advantage of the differences and complementarities between PET and CT. We validated the proposed ISA-Net method on two clinical datasets, a soft tissue sarcoma(STS) and a head and neck tumor(HECKTOR) dataset, and compared with other attention methods for tumor segmentation. The DSC score of 0.8378 on STS dataset and 0.8076 on HECKTOR dataset show that ISA-Net method achieves better segmentation performance and has better generalization. Conclusions: The method proposed in this paper is based on multi-modal medical image tumor segmentation, which can effectively utilize the difference and complementarity of different modes. The method can also be applied to other multi-modal data or single-modal data by proper adjustment.

eess.IV↗

A highly accurate perfectly-matched-layer boundary integral equation solver for acoustic layered-medium problems

Based on the perfectly matched layer (PML) technique, this paper develops a high-accuracy boundary integral equation (BIE) solver for acoustic scattering problems in locally defected layered media in both two and three dimensions. The original scattering problem is truncated onto a bounded domain by the PML. Assuming the vanishing of the scattered field on the PML boundary, we derive BIEs on local defects only in terms of using PML-transformed free-space Green's function, and the four standard integral operators: single-layer, double-layer, transpose of double-layer, and hyper-singular boundary integral operators. The hyper-singular integral operator is transformed into a combination of weakly-singular integral operators and tangential derivatives. We develop a high-order Chebyshev-based rectangular-polar singular-integration solver to discretize all weakly-singular integrals. Numerical experiments for both two- and three-dimensional problems are carried out to demonstrate the accuracy and efficiency of the proposed solver.

math.NA↗

BI AVAN: Brain inspired Adversarial Visual Attention Network

Visual attention is a fundamental mechanism in the human brain, and it inspires the design of attention mechanisms in deep neural networks. However, most of the visual attention studies adopted eye-tracking data rather than the direct measurement of brain activity to characterize human visual attention. In addition, the adversarial relationship between the attention-related objects and attention-neglected background in the human visual system was not fully exploited. To bridge these gaps, we propose a novel brain-inspired adversarial visual attention network (BI-AVAN) to characterize human visual attention directly from functional brain activity. Our BI-AVAN model imitates the biased competition process between attention-related/neglected objects to identify and locate the visual objects in a movie frame the human brain focuses on in an unsupervised manner. We use independent eye-tracking data as ground truth for validation and experimental results show that our model achieves robust and promising results when inferring meaningful human visual attention and mapping the relationship between brain activities and visual stimuli. Our BI-AVAN model contributes to the emerging field of leveraging the brain's functional architecture to inspire and guide the model design in artificial intelligence (AI), e.g., deep neural networks.

cs.CV↗

Hierarchical Few-Shot Object Detection: Problem, Benchmark and Method

Few-shot object detection (FSOD) is to detect objects with a few examples. However, existing FSOD methods do not consider hierarchical fine-grained category structures of objects that exist widely in real life. For example, animals are taxonomically classified into orders, families, genera and species etc. In this paper, we propose and solve a new problem called hierarchical few-shot object detection (Hi-FSOD), which aims to detect objects with hierarchical categories in the FSOD paradigm. To this end, on the one hand, we build the first large-scale and high-quality Hi-FSOD benchmark dataset HiFSOD-Bird, which contains 176,350 wild-bird images falling to 1,432 categories. All the categories are organized into a 4-level taxonomy, consisting of 32 orders, 132 families, 572 genera and 1,432 species. On the other hand, we propose the first Hi-FSOD method HiCLPL, where a hierarchical contrastive learning approach is developed to constrain the feature space so that the feature distribution of objects is consistent with the hierarchical taxonomy and the model's generalization power is strengthened. Meanwhile, a probabilistic loss is designed to enable the child nodes to correct the classification errors of their parent nodes in the taxonomy. Extensive experiments on the benchmark dataset HiFSOD-Bird show that our method HiCLPL outperforms the existing FSOD methods.

cs.CV↗

Floodgate: inference for model-free variable importance

Many modern applications seek to understand the relationship between an outcome variable $Y$ and a covariate $X$ in the presence of a (possibly high-dimensional) confounding variable $Z$. Although much attention has been paid to testing \emph{whether} $Y$ depends on $X$ given $Z$, in this paper we seek to go beyond testing by inferring the \emph{strength} of that dependence. We first define our estimand, the minimum mean squared error (mMSE) gap, which quantifies the conditional relationship between $Y$ and $X$ in a way that is deterministic, model-free, interpretable, and sensitive to nonlinearities and interactions. We then propose a new inferential approach called \emph{floodgate} that can leverage any working regression function chosen by the user (allowing, e.g., it to be fitted by a state-of-the-art machine learning algorithm or be derived from qualitative domain knowledge) to construct asymptotic confidence bounds, and we apply it to the mMSE gap. \acc{We additionally show that floodgate's accuracy (distance from confidence bound to estimand) is adaptive to the error of the working regression function.} We then show we can apply the same floodgate principle to a different measure of variable importance when $Y$ is binary. Finally, we demonstrate floodgate's performance in a series of simulations and apply it to data from the UK Biobank to infer the strengths of dependence of platelet count on various groups of genetic mutations.

stat.ME↗

A Multi-Channel Next POI Recommendation Framework with Multi-Granularity Check-in Signals

Current study on next POI recommendation mainly explores user sequential transitions with the fine-grained individual-user POI check-in trajectories only, which suffers from the severe check-in data sparsity issue. In fact, coarse-grained signals (i.e., region- and global-level check-ins) in such sparse check-ins would also benefit to augment user preference learning. Specifically, our data analysis unveils that user movement exhibits noticeable patterns w.r.t. the regions of visited POIs. Meanwhile, the global all-user check-ins can help reflect sequential regularities shared by the crowd. We are, therefore, inspired to propose the MCMG: a Multi-Channel next POI recommendation framework with Multi-Granularity signals categorized from two orthogonal perspectives, i.e., fine-coarse grained check-ins at either POI/region level or local/global level. Being equipped with three modules (i.e., global user behavior encoder, local multi-channel encoder, and region-aware weighting strategy), MCMG is capable of capturing both fine- and coarse-grained sequential regularities as well as exploring the dynamic impact of multi-channel by differentiating the region check-in patterns. Extensive experiments on four real-world datasets show that our MCMG significantly outperforms state-of-the-art next POI recommendation approaches.

cs.IR↗

Taming Hybrid-Cloud Fast and Scalable Graph Analytics at Twitter

We have witnessed a boosted demand for graph analytics at Twitter in recent years, and graph analytics has become one of the key parts of Twitter's large-scale data analytics and machine learning for driving engagement, serving the most relevant content, and promoting healthier conversations. However, infrastructure for graph analytics has historically not been an area of investment at Twitter, resulting in a long timeline and huge engineering effort for each project to deal with graphs at the Twitter scale. How do we build a unified graph analytics user experience to fulfill modern data analytics on various graph scales spanning from thousands to hundreds of billions of vertices and edges? To bring fast and scalable graph analytics capability into production, we investigate the challenges we are facing in large-scale graph analytics at Twitter and propose a unified graph analytics platform for efficient, scalable, and reliable graph analytics across on-premises and cloud, to fulfill the requirements of diverse graph use cases and challenging scales. We also conduct quantitative benchmarking on Twitter's production-level graph use cases between popular graph analytics frameworks to certify our solution.

cs.DB↗

Automatically Discovering Novel Visual Categories with Self-supervised Prototype Learning

This paper tackles the problem of novel category discovery (NCD), which aims to discriminate unknown categories in large-scale image collections. The NCD task is challenging due to the closeness to the real-world scenarios, where we have only encountered some partial classes and images. Unlike other works on the NCD, we leverage the prototypes to emphasize the importance of category discrimination and alleviate the issue of missing annotations of novel classes. Concretely, we propose a novel adaptive prototype learning method consisting of two main stages: prototypical representation learning and prototypical self-training. In the first stage, we obtain a robust feature extractor, which could serve for all images with base and novel categories. This ability of instance and category discrimination of the feature extractor is boosted by self-supervised learning and adaptive prototypes. In the second stage, we utilize the prototypes again to rectify offline pseudo labels and train a final parametric classifier for category clustering. We conduct extensive experiments on four benchmark datasets and demonstrate the effectiveness and robustness of the proposed method with state-of-the-art performance.

cs.CV↗

Trajectory Prediction with Graph-based Dual-scale Context Fusion

Motion prediction for traffic participants is essential for a safe and robust automated driving system, especially in cluttered urban environments. However, it is highly challenging due to the complex road topology as well as the uncertain intentions of the other agents. In this paper, we present a graph-based trajectory prediction network named the Dual Scale Predictor (DSP), which encodes both the static and dynamical driving context in a hierarchical manner. Different from methods based on a rasterized map or sparse lane graph, we consider the driving context as a graph with two layers, focusing on both geometrical and topological features. Graph neural networks (GNNs) are applied to extract features with different levels of granularity, and features are subsequently aggregated with attention-based inter-layer networks, realizing better local-global feature fusion. Following the recent goal-driven trajectory prediction pipeline, goal candidates with high likelihood for the target agent are extracted, and predicted trajectories are generated conditioned on these goals. Thanks to the proposed dual-scale context fusion network, our DSP is able to generate accurate and human-like multi-modal trajectories. We evaluate the proposed method on the large-scale Argoverse motion forecasting benchmark, and it achieves promising results, outperforming the recent state-of-the-art methods.

cs.RO↗

TJ4DRadSet: A 4D Radar Dataset for Autonomous Driving

The next-generation high-resolution automotive radar (4D radar) can provide additional elevation measurement and denser point clouds, which has great potential for 3D sensing in autonomous driving. In this paper, we introduce a dataset named TJ4DRadSet with 4D radar points for autonomous driving research. The dataset was collected in various driving scenarios, with a total of 7757 synchronized frames in 44 consecutive sequences, which are well annotated with 3D bounding boxes and track ids. We provide a 4D radar-based 3D object detection baseline for our dataset to demonstrate the effectiveness of deep learning methods for 4D radar point clouds. The dataset can be accessed via the following link: https://github.com/TJRadarLab/TJ4DRadSet.

cs.CV↗