arXiv subjects

Nassir Navab

Publications and source records attributed to Nassir Navab.

At least 109 records · Page 6Linked to original sources

arXiv2025

VeLU: Variance-enhanced Learning Unit for Deep Neural Networks

Activation functions play a critical role in deep neural networks by shaping gradient flow, optimization stability, and generalization. While ReLU remains widely used due to its simplicity, it suffers from gradient sparsity and dead-neuron issues and offers no adaptivity to input statistics. Smooth alternatives such as Swish and GELU improve gradient propagation but still apply a fixed transformation regardless of the activation distribution. In this paper, we propose VeLU, a Variance-enhanced Learning Unit that introduces variance-aware and distributionally aligned nonlinearity through a principled combination of ArcTan-ArcSin transformations, adaptive scaling, and Wasserstein-2 regularization (Optimal Transport). This design enables VeLU to modulate its response based on local activation variance, mitigate internal covariate shift at the activation level, and improve training stability without adding learnable parameters or architectural overhead. Extensive experiments across six deep neural networks show that VeLU outperforms ReLU, ReLU6, Swish, and GELU on 12 vision benchmarks. The implementation of VeLU is publicly available in GitHub.

cs.LG↗

arXiv2025

Language-Guided Open-World Anomaly Segmentation

Open-world and anomaly segmentation methods seek to enable autonomous driving systems to detect and segment both known and unknown objects in real-world scenes. However, existing methods do not assign semantically meaningful labels to unknown regions, and distinguishing and learning representations for unknown classes remains difficult. While open-vocabulary segmentation methods show promise in generalizing to novel classes, they require a fixed inference vocabulary and thus cannot be directly applied to anomaly segmentation where unknown classes are unconstrained. We propose Clipomaly, the first CLIP-based open-world and anomaly segmentation method for autonomous driving. Our zero-shot approach requires no anomaly-specific training data and leverages CLIP's shared image-text embedding space to both segment unknown objects and assign human-interpretable names to them. Unlike open-vocabulary methods, our model dynamically extends its vocabulary at inference time without retraining, enabling robust detection and naming of anomalies beyond common class definitions such as those in Cityscapes. Clipomaly achieves state-of-the-art performance on established anomaly segmentation benchmarks while providing interpretability and flexibility essential for practical deployment.

cs.CV↗

arXiv2025

MonoGSDF: Exploring Monocular Geometric Cues for Gaussian Splatting-Guided Implicit Surface Reconstruction

Accurate meshing from monocular images remains a key challenge in 3D vision. While state-of-the-art 3D Gaussian Splatting (3DGS) methods excel at synthesizing photorealistic novel views through rasterization-based rendering, their reliance on sparse, explicit primitives severely limits their ability to recover watertight and topologically consistent 3D surfaces.We introduce MonoGSDF, a novel method that couples Gaussian-based primitives with a neural Signed Distance Field (SDF) for high-quality reconstruction. During training, the SDF guides Gaussians' spatial distribution, while at inference, Gaussians serve as priors to reconstruct surfaces, eliminating the need for memory-intensive Marching Cubes. To handle arbitrary-scale scenes, we propose a scaling strategy for robust generalization. A multi-resolution training scheme further refines details and monocular geometric cues from off-the-shelf estimators enhance reconstruction quality. Experiments on real-world datasets show MonoGSDF outperforms prior methods while maintaining efficiency.

cs.CV↗

arXiv2025

US-X Complete: A Multi-Modal Approach to Anatomical 3D Shape Recovery

Ultrasound offers a radiation-free, cost-effective solution for real-time visualization of spinal landmarks, paraspinal soft tissues and neurovascular structures, making it valuable for intraoperative guidance during spinal procedures. However, ultrasound suffers from inherent limitations in visualizing complete vertebral anatomy, in particular vertebral bodies, due to acoustic shadowing effects caused by bone. In this work, we present a novel multi-modal deep learning method for completing occluded anatomical structures in 3D ultrasound by leveraging complementary information from a single X-ray image. To enable training, we generate paired training data consisting of: (1) 2D lateral vertebral views that simulate X-ray scans, and (2) 3D partial vertebrae representations that mimic the limited visibility and occlusions encountered during ultrasound spine imaging. Our method integrates morphological information from both imaging modalities and demonstrates significant improvements in vertebral reconstruction (p < 0.001) compared to state of art in 3D ultrasound vertebral completion. We perform phantom studies as an initial step to future clinical translation, and achieve a more accurate, complete volumetric lumbar spine visualization overlayed on the ultrasound scan without the need for registration with preoperative modalities such as computed tomography. This demonstrates that integrating a single X-ray projection mitigates ultrasound's key limitation while preserving its strengths as the primary imaging modality. Code and data can be found at https://github.com/miruna20/US-X-Complete

cs.CV↗

arXiv2025

PRISM-0: A Predicate-Rich Scene Graph Generation Framework for Zero-Shot Open-Vocabulary Tasks

In Scene Graph Generation (SGG), structured representations are extracted from visual inputs as object nodes and connecting predicates, enabling image-based reasoning for diverse downstream tasks. While fully supervised SGG has improved steadily, it suffers from training bias due to limited curated data and long-tail predicate distributions, leading to poor predicate diversity and degraded downstream performance. We present PRISM-0, a zero-shot open-vocabulary SGG framework that leverages foundation models in a bottom-up pipeline to capture a broad spectrum of predicates. Detected object pairs are filtered, described via a Vision-Language Model (VLM), and processed by a Large Language Model (LLM) to generate fine- and coarse-grained predicates, which are then validated by a Visual Question Answering (VQA) model. PRISM-0 modular, dataset-independent design enriches existing SGG datasets such as Visual Genome and produces diverse, unbiased graphs. While operating entirely in a zero-shot setting, PRISM-0 achieves performance on par with state-of-the-art weakly-supervised models on SGG benchmarks and even state-of-the-art supervised methods in tasks such as Sentence-to-Graph Retrieval.

cs.CV↗

arXiv2025

How Far Are Surgeons from Surgical World Models? A Pilot Study on Zero-shot Surgical Video Generation with Expert Assessment

Foundation models in video generation are demonstrating remarkable capabilities as potential world models for simulating the physical world. However, their application in high-stakes domains like surgery, which demand deep, specialized causal knowledge rather than general physical rules, remains a critical unexplored gap. To systematically address this challenge, we present SurgVeo, the first expert-curated benchmark for video generation model evaluation in surgery, and the Surgical Plausibility Pyramid (SPP), a novel, four-tiered framework tailored to assess model outputs from basic appearance to complex surgical strategy. On the basis of the SurgVeo benchmark, we task the advanced Veo-3 model with a zero-shot prediction task on surgical clips from laparoscopic and neurosurgical procedures. A panel of four board-certified surgeons evaluates the generated videos according to the SPP. Our results reveal a distinct "plausibility gap": while Veo-3 achieves exceptional Visual Perceptual Plausibility, it fails critically at higher levels of the SPP, including Instrument Operation Plausibility, Environment Feedback Plausibility, and Surgical Intent Plausibility. This work provides the first quantitative evidence of the chasm between visually convincing mimicry and causal understanding in surgical AI. Our findings from SurgVeo and the SPP establish a crucial foundation and roadmap for developing future models capable of navigating the complexities of specialized, real-world healthcare domains.

cs.CV↗

arXiv2025

LiteTracker: Leveraging Temporal Causality for Accurate Low-latency Tissue Tracking

Tissue tracking plays a critical role in various surgical navigation and extended reality (XR) applications. While current methods trained on large synthetic datasets achieve high tracking accuracy and generalize well to endoscopic scenes, their runtime performances fail to meet the low-latency requirements necessary for real-time surgical applications. To address this limitation, we propose LiteTracker, a low-latency method for tissue tracking in endoscopic video streams. LiteTracker builds on a state-of-the-art long-term point tracking method, and introduces a set of training-free runtime optimizations. These optimizations enable online, frame-by-frame tracking by leveraging a temporal memory buffer for efficient feature reuse and utilizing prior motion for accurate track initialization. LiteTracker demonstrates significant runtime improvements being around 7x faster than its predecessor and 2x than the state-of-the-art. Beyond its primary focus on efficiency, LiteTracker delivers high-accuracy tracking and occlusion prediction, performing competitively on both the STIR and SuPer datasets. We believe LiteTracker is an important step toward low-latency tissue tracking for real-time surgical applications in the operating room. Our code is publicly available at https://github.com/ImFusionGmbH/lite-tracker.

cs.CV↗

arXiv2025

Improving Robustness to Out-of-Distribution States in Imitation Learning via Deep Koopman-Boosted Diffusion Policy

Integrating generative models with action chunking has shown significant promise in imitation learning for robotic manipulation. However, the existing diffusion-based paradigm often struggles to capture strong temporal dependencies across multiple steps, particularly when incorporating proprioceptive input. This limitation can lead to task failures, where the policy overfits to proprioceptive cues at the expense of capturing the visually derived features of the task. To overcome this challenge, we propose the Deep Koopman-boosted Dual-branch Diffusion Policy (D3P) algorithm. D3P introduces a dual-branch architecture to decouple the roles of different sensory modality combinations. The visual branch encodes the visual observations to indicate task progression, while the fused branch integrates both visual and proprioceptive inputs for precise manipulation. Within this architecture, when the robot fails to accomplish intermediate goals, such as grasping a drawer handle, the policy can dynamically switch to execute action chunks generated by the visual branch, allowing recovery to previously observed states and facilitating retrial of the task. To further enhance visual representation learning, we incorporate a Deep Koopman Operator module that captures structured temporal dynamics from visual inputs. During inference, we use the test-time loss of the generative model as a confidence signal to guide the aggregation of the temporally overlapping predicted action chunks, thereby enhancing the reliability of policy execution. In simulation experiments across six RLBench tabletop tasks, D3P outperforms the state-of-the-art diffusion policy by an average of 14.6\%. On three real-world robotic manipulation tasks, it achieves a 15.0\% improvement. Code: https://github.com/dianyeHuang/D3P.

cs.RO↗

arXiv2025

RayPose: Ray Bundling Diffusion for Template Views in Unseen 6D Object Pose Estimation

Typical template-based object pose pipelines estimate the pose by retrieving the closest matching template and aligning it with the observed image. However, failure to retrieve the correct template often leads to inaccurate pose predictions. To address this, we reformulate template-based object pose estimation as a ray alignment problem, where the viewing directions from multiple posed template images are learned to align with a non-posed query image. Inspired by recent progress in diffusion-based camera pose estimation, we embed this formulation into a diffusion transformer architecture that aligns a query image with a set of posed templates. We reparameterize object rotation using object-centered camera rays and model object translation by extending scale-invariant translation estimation to dense translation offsets. Our model leverages geometric priors from the templates to guide accurate query pose inference. A coarse-to-fine training strategy based on narrowed template sampling improves performance without modifying the network architecture. Extensive experiments across multiple benchmark datasets show competitive results of our method compared to state-of-the-art approaches in unseen object pose estimation.

cs.CV↗

arXiv2025

Freehand 3D Ultrasound Imaging: Sim-in-the-Loop Probe Pose Optimization via Visual Servoing

Freehand 3D ultrasound (US) imaging using conventional 2D probes offers flexibility and accessibility for diverse clinical applications but faces challenges in accurate probe pose estimation. Traditional methods depend on costly tracking systems, while neural network-based methods struggle with image noise and error accumulation, compromising reconstruction precision. We propose a cost-effective and versatile solution that leverages lightweight cameras and visual servoing in simulated environments for precise 3D US imaging. These cameras capture visual feedback from a textured planar workspace. To counter occlusions and lighting issues, we introduce an image restoration method that reconstructs occluded regions by matching surrounding texture patterns. For pose estimation, we develop a simulation-in-the-loop approach, which replicates the system setup in simulation and iteratively minimizes pose errors between simulated and real-world observations. A visual servoing controller refines the alignment of camera views, improving translational estimation by optimizing image alignment. Validations on a soft vascular phantom, a 3D-printed conical model, and a human arm demonstrate the robustness and accuracy of our approach, with Hausdorff distances to the reference reconstructions of 0.359 mm, 1.171 mm, and 0.858 mm, respectively. These results confirm the method's potential for reliable freehand 3D US reconstruction.

cs.RO↗

arXiv2025

UltraScatter: Ray-Based Simulation of Ultrasound Scattering

Traditional ultrasound simulation methods solve wave equations numerically, achieving high accuracy but at substantial computational cost. Faster alternatives based on convolution with precomputed impulse responses remain relatively slow, often requiring several minutes to generate a full B-mode image. We introduce UltraScatter, a probabilistic ray tracing framework that models ultrasound scattering efficiently and realistically. Tissue is represented as a volumetric field of scattering probability and scattering amplitude, and ray interactions are simulated via free-flight delta tracking. Scattered rays are traced to the transducer, with phase information incorporated through a linear time-of-flight model. Integrated with plane-wave imaging and beamforming, our parallelized ray tracing architecture produces B-mode images within seconds. Validation with phantom data shows realistic speckle and inclusion patterns, positioning UltraScatter as a scalable alternative to wave-based methods.

physics.med-ph↗

arXiv2025

Does Machine Unlearning Truly Remove Knowledge?

In recent years, Large Language Models (LLMs) have achieved remarkable advancements, drawing significant attention from the research community. Their capabilities are largely attributed to large-scale architectures, which require extensive training on massive datasets. However, such datasets often contain sensitive or copyrighted content sourced from the public internet, raising concerns about data privacy and ownership. Regulatory frameworks, such as the General Data Protection Regulation (GDPR), grant individuals the right to request the removal of such sensitive information. This has motivated the development of machine unlearning algorithms that aim to remove specific knowledge from models without the need for costly retraining. Despite these advancements, evaluating the efficacy of unlearning algorithms remains a challenge due to the inherent complexity and generative nature of LLMs. In this work, we introduce a comprehensive auditing framework for unlearning evaluation, comprising three benchmark datasets, six unlearning algorithms, and five prompt-based auditing methods. By using various auditing algorithms, we evaluate the effectiveness and robustness of different unlearning strategies. To explore alternatives beyond prompt-based auditing, we propose a novel technique that leverages intermediate activation perturbations, addressing the limitations of auditing methods that rely solely on model inputs and outputs.

cs.LG↗

arXiv2025

Knowledge Graph Sparsification for GNN-based Rare Disease Diagnosis

Rare genetic disease diagnosis faces critical challenges: insufficient patient data, inaccessible full genome sequencing, and the immense number of possible causative genes. These limitations cause prolonged diagnostic journeys, inappropriate treatments, and critical delays, disproportionately affecting patients in resource-limited settings where diagnostic tools are scarce. We propose RareNet, a subgraph-based Graph Neural Network that requires only patient phenotypes to identify the most likely causal gene and retrieve focused patient subgraphs for targeted clinical investigation. RareNet can function as a standalone method or serve as a pre-processing or post-processing filter for other candidate gene prioritization methods, consistently enhancing their performance while potentially enabling explainable insights. Through comprehensive evaluation on two biomedical datasets, we demonstrate competitive and robust causal gene prediction and significant performance gains when integrated with other frameworks. By requiring only phenotypic data, which is readily available in any clinical setting, RareNet democratizes access to sophisticated genetic analysis, offering particular value for underserved populations lacking advanced genomic infrastructure.

cs.LG↗

arXiv2025

DeepAf: One-Shot Spatiospectral Auto-Focus Model for Digital Pathology

While Whole Slide Imaging (WSI) scanners remain the gold standard for digitizing pathology samples, their high cost limits accessibility in many healthcare settings. Other low-cost solutions also face critical limitations: automated microscopes struggle with consistent focus across varying tissue morphology, traditional auto-focus methods require time-consuming focal stacks, and existing deep-learning approaches either need multiple input images or lack generalization capability across tissue types and staining protocols. We introduce a novel automated microscopic system powered by DeepAf, a novel auto-focus framework that uniquely combines spatial and spectral features through a hybrid architecture for single-shot focus prediction. The proposed network automatically regresses the distance to the optimal focal point using the extracted spatiospectral features and adjusts the control parameters for optimal image outcomes. Our system transforms conventional microscopes into efficient slide scanners, reducing focusing time by 80% compared to stack-based methods while achieving focus accuracy of 0.18 μm on the same-lab samples, matching the performance of dual-image methods (0.19 μm) with half the input requirements. DeepAf demonstrates robust cross-lab generalization with only 0.72% false focus predictions and 90% of predictions within the depth of field. Through an extensive clinical study of 536 brain tissue samples, our system achieves 0.90 AUC in cancer classification at 4x magnification, a significant achievement at lower magnification than typical 20x WSI scans. This results in a comprehensive hardware-software design enabling accessible, real-time digital pathology in resource-constrained settings while maintaining diagnostic accuracy.

cs.CV↗

arXiv2025

OracleGS: Grounding Generative Priors for Sparse-View Gaussian Splatting

Sparse-view novel view synthesis is fundamentally ill-posed due to severe geometric ambiguity. Current methods are caught in a trade-off: regressive models are geometrically faithful but incomplete, whereas generative models can complete scenes but often introduce structural inconsistencies. We propose OracleGS, a novel framework that reconciles generative completeness with regressive fidelity for sparse view Gaussian Splatting. Instead of using generative models to patch incomplete reconstructions, our "propose-and-validate" framework first leverages a pre-trained 3D-aware diffusion model to synthesize novel views to propose a complete scene. We then repurpose a multi-view stereo (MVS) model as a 3D-aware oracle to validate the 3D uncertainties of generated views, using its attention maps to reveal regions where the generated views are well-supported by multi-view evidence versus where they fall into regions of high uncertainty due to occlusion, lack of texture, or direct inconsistency. This uncertainty signal directly guides the optimization of a 3D Gaussian Splatting model via an uncertainty-weighted loss. Our approach conditions the powerful generative prior on multi-view geometric evidence, filtering hallucinatory artifacts while preserving plausible completions in under-constrained regions, outperforming state-of-the-art methods on datasets including Mip-NeRF 360 and NeRF Synthetic.

cs.CV↗

arXiv2025

Foundation Visual Encoders Are Secretly Few-Shot Anomaly Detectors

Few-shot anomaly detection streamlines and simplifies industrial safety inspection. However, limited samples make accurate differentiation between normal and abnormal features challenging, and even more so under category-agnostic conditions. Large-scale pre-training of foundation visual encoders has advanced many fields, as the enormous quantity of data helps to learn the general distribution of normal images. We observe that the anomaly amount in an image directly correlates with the difference in the learnt embeddings and utilize this to design a few-shot anomaly detector termed FoundAD. This is done by learning a nonlinear projection operator onto the natural image manifold. The simple operator acts as an effective tool for anomaly detection to characterize and identify out-of-distribution regions in an image. Extensive experiments show that our approach supports multi-class detection and achieves competitive performance while using substantially fewer parameters than prior methods. Backed up by evaluations with multiple foundation encoders, including fresh DINOv3, we believe this idea broadens the perspective on foundation features and advances the field of few-shot anomaly detection.

cs.CV↗

arXiv2025

SpeechCT-CLIP: Distilling Text-Image Knowledge to Speech for Voice-Native Multimodal CT Analysis

Spoken communication plays a central role in clinical workflows. In radiology, for example, most reports are created through dictation. Yet, nearly all medical AI systems rely exclusively on written text. In this work, we address this gap by exploring the feasibility of learning visual-language representations directly from spoken radiology reports. Specifically, we synthesize a large-scale dataset (Speech-RATE) of spoken radiology reports and train SpeechCT-CLIP, a contrastive model that aligns speech and 3D CT volumes in a shared representation space. While naive speech-based models underperform compared to text-trained counterparts, we show that knowledge distillation from a pretrained text-image CLIP model effectively transfers semantic alignment capabilities from text to speech, substantially narrowing this gap. Experiments demonstrate improved zero-shot classification F1 from 0.623 to 0.705, recovering 88% of the performance difference, and strong retrieval results without requiring text at inference. These findings highlight speech as a practical alternative to text in multimodal pretraining and open the door to voice-driven diagnostic support tools in clinical practice.

eess.AS↗

arXiv2025

BridgeSplat: Bidirectionally Coupled CT and Non-Rigid Gaussian Splatting for Deformable Intraoperative Surgical Navigation

We introduce BridgeSplat, a novel approach for deformable surgical navigation that couples intraoperative 3D reconstruction with preoperative CT data to bridge the gap between surgical video and volumetric patient data. Our method rigs 3D Gaussians to a CT mesh, enabling joint optimization of Gaussian parameters and mesh deformation through photometric supervision. By parametrizing each Gaussian relative to its parent mesh triangle, we enforce alignment between Gaussians and mesh and obtain deformations that can be propagated back to update the CT. We demonstrate BridgeSplat's effectiveness on visceral pig surgeries and synthetic data of a human liver under simulation, showing sensible deformations of the preoperative CT on monocular RGB data. Code, data, and additional resources can be found at https://maxfehrentz.github.io/ct-informed-splatting/ .

cs.CV↗