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Pejman Kheradmand

Publications and source records attributed to Pejman Kheradmand.

8 recordsLinked to original sources

Helical Tendon-Driven Continuum Robot with Programmable Follow-the-Leader Operation

Spinal cord stimulation (SCS) is widely used for pain management and has recently shown promise in promoting functional recovery following spinal cord injury. Effective activation of motor neurons requires accurate placement of SCS leads in the ventral or lateral epidural space, where corticospinal and rubrospinal motor fibers are located, a task that remains challenging with conventional manual steering. This study presents a static modeling framework for ExoNav, a steerable robotic tool designed to enable precise navigation to ventral and lateral epidural targets. A Cosserat rod formulation is employed to relate tendon actuation forces to the robot shape, and a simulation environment is developed based on this model, incorporating gravity as an external load. Experimental validation across four prototypes yields tip position root mean square errors (RMSEs) of 1.76 mm, 2.33 mm, 2.18 mm, and 1.33 mm, corresponding to 2.3 , 3.1, 3.4, and 2.1 percent of the robot length, respectively. Owing to its helical deformation under actuation, ExoNav enables follow-the-leader (FTL) motion when combined with insertion and rotation degrees of freedom, which is demonstrated in both simulation and experiments. The proposed simulation computes optimal tendon tensions to track desired FTL paths under gravity-induced deformation. Three FTL experiments show repeatable end-effector alignment with a maximum RMSE of 3.75 mm (less than 5 percent of the robot length). Finally, phantom experiments demonstrate successful teleoperated navigation to ventral and lateral spinal cord targets, as well as the dorsal root ganglia, highlighting ExoNav potential for both motor function recovery and pain management.

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Towards a Novel Wearable Robotic Vest for Hemorrhage Suppression

This paper introduces a novel robotic system designed to manage severe bleeding in emergency scenarios, including unique environments like space stations. The robot features a shape-adjustable "ring mechanism", transitioning from a circular to an elliptical configuration to adjust wound coverage across various anatomical regions. We developed various arms for this ring mechanism with varying flexibilities to improve adaptability when applied to non-extremities of the body (abdomen, back, neck, etc.). To apply equal and constant pressure across the wound, we developed an inflatable ring and airbag balloon that are compatible with this shape-changing ring mechanism. A series of experiments focused on evaluating various ring arm configurations to characterize their bending stiffness. Subsequent experiments measured the force exerted by the airbag balloon system using a digital scale. Despite its promising performance, certain limitations related to coverage area are identified. The shape-changing effect of the device is limited to scenarios involving partially inflated or deflated airbag balloons, and cannot fully conform to complex anatomical regions. Finally, the device was tested on casualty simulation kits, where it successfully demonstrated its ability to control simulated bleeding.

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The OncoReach Stylet for Brachytherapy: Design Evaluation and Pilot Study

Cervical cancer accounts for a significant portion of the global cancer burden among women. Interstitial brachytherapy (ISBT) is a standard procedure for treating cervical cancer; it involves placing a radioactive source through a straight hollow needle within or in close proximity to the tumor and surrounding tissue. However, the use of straight needles limits surgical planning to a linear needle path. We present the OncoReach stylet, a handheld, tendon-driven steerable stylet designed for compatibility with standard ISBT 15- and 13-gauge needles. Building upon our prior work, we evaluated design parameters like needle gauge, spherical joint count and spherical joint placement, including an asymmetric disk design to identify a configuration that maximizes bending compliance while retaining axial stiffness. Free space experiments quantified tip deflection across configurations, and a two-tube Cosserat rod model accurately predicted the centerline shape of the needle for most trials. The best performing configuration was integrated into a reusable handheld prototype that enables manual actuation. A patient-derived, multi-composite phantom model of the uterus and pelvis was developed to conduct a pilot study of the OncoReach steerable stylet with one expert user. Results showed the ability to steer from less-invasive, medial entry points to reach the lateral-most targets, underscoring the significance of steerable stylets.

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Bilinear Model Predictive Control Framework of the OncoReach, a Tendon-Driven Steerable Stylet for Brachytherapy

Steerable needles have the potential to improve interstitial brachytherapy by enabling curved trajectories that avoid sensitive anatomical structures. However, existing modeling and control approaches are primarily developed for custom needle designs and are not directly applicable to stylets compatible with commercially available clinical needles. This paper presents a bilinear model predictive control (MPC) framework for a tendon-driven steerable stylet integrated with a standard brachytherapy needle. \textcolor{black}{A geometric bilinear model is formulated with three virtual inputs (an insertion speed and two bending rates) which are mapped to physically realizable inputs consisting of the insertion speed and the associated tendon tensions.} The approach is validated through simulations and physical insertion experiments in tissue-mimicking phantom material using image-based tip tracking. While open-loop model validation yielded estimation errors below $2$~mm, corresponding to $3\%$ of the inserted needle length, and closed-loop fixed-target tracking achieved an error as low as $1.45$~mm, corresponding to $1.7\%$ of the inserted length, experiments showed larger position errors in certain bending directions, reaching $8.3$~mm, or $7.8\%$ of the inserted length. Overall, the results demonstrate the feasibility of fixed-target positioning and moving-target trajectory tracking for clinically compatible steerable brachytherapy systems, while highlighting necessary areas for future improvements in calibration and sensing.

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A Comprehensive General Model of Tendon-Actuated Concentric Tube Robots with Multiple Tubes and Tendons

Tendon-actuated concentric tube mechanisms combine the advantages of tendon-driven continuum robots and concentric tube robots while addressing their respective limitations. They overcome the restricted degrees of freedom often seen in tendon-driven designs, and mitigate issues such as snapping instability associated with concentric tube robots. However, a complete and general mechanical model for these systems remains an open problem. In this work, we propose a Cosserat rod-based framework for modeling the general case of $n$ concentric tubes, each actuated by $m_i$ tendons, where $i = \{1, \ldots, n\}$. The model allows each tube to twist and elongate while enforcing a shared centerline for bending. We validate the proposed framework through experiments with two-tube and three tube assemblies under various tendon routing configurations, achieving tip prediction errors $<4\%$ of the robot's total length. We further demonstrate the model's generality by applying it to existing robots in the field, where maximum tip deviations remain around $5\%$ of the total length. This model provides a foundation for accurate shape estimation and control of advanced tendon-actuated concentric tube robots.

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Tendon-Actuated Concentric Tube Endonasal Robot (TACTER)

Endoscopic endonasal approaches (EEA) have become more prevalent for minimally invasive skull base and sinus surgeries. However, rigid scopes and tools significantly decrease the surgeon's ability to operate in tight anatomical spaces and avoid critical structures such as the internal carotid artery and cranial nerves. This paper proposes a novel tendon-actuated concentric tube endonasal robot (TACTER) design in which two tendon-actuated robots are concentric to each other, resulting in an outer and inner robot that can bend independently. The outer robot is a unidirectionally asymmetric notch (UAN) nickel-titanium robot, and the inner robot is a 3D-printed bidirectional robot, with a nickel-titanium bending member. In addition, the inner robot can translate axially within the outer robot, allowing the tool to traverse through structures while bending, thereby executing follow-the-leader motion. A Cosserat-rod based mechanical model is proposed that uses tendon tension of both tendon-actuated robots and the relative translation between the robots as inputs and predicts the TACTER tip position for varying input parameters. The model is validated with experiments, and a human cadaver experiment is presented to demonstrate maneuverability from the nostril to the sphenoid sinus. This work presents the first tendon-actuated concentric tube (TACT) dexterous robotic tool capable of performing follow-the-leader motion within natural nasal orifices to cover workspaces typically required for a successful EEA.

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ExoNav II: Design of a Robotic Tool with Follow-the-Leader Motion Capability for Lateral and Ventral Spinal Cord Stimulation (SCS)

Spinal cord stimulation (SCS) electrodes are traditionally placed in the dorsal epidural space to stimulate the dorsal column fibers for pain therapy. Recently, SCS has gained attention in restoring gait. However, the motor fibers triggering locomotion are located in the ventral and lateral spinal cord. Currently, SCS electrodes are steered manually, making it difficult to navigate them to the lateral and ventral motor fibers in the spinal cord. In this work, we propose a helically micro-machined continuum robot that can bend in a helical shape when subjected to actuation tendon forces. Using a stiff outer tube and adding translational and rotational degrees of freedom, this helical continuum robot can perform follow-the-leader (FTL) motion. We propose a kinematic model to relate tendon stroke and geometric parameters of the robot's helical shape to its acquired trajectory and end-effector position. We evaluate the proposed kinematic model and the robot's FTL motion capability experimentally. The stroke-based method, which links tendon stroke values to the robot's shape, showed inaccuracies with a 19.84 mm deviation and an RMSE of 14.42 mm for 63.6 mm of robot's length bending. The position-based method, using kinematic equations to map joint space to task space, performed better with a 10.54 mm deviation and an RMSE of 8.04 mm. Follow-the-leader experiments showed deviations of 11.24 mm and 7.32 mm, with RMSE values of 8.67 mm and 5.18 mm for the stroke-based and position-based methods, respectively. Furthermore, end-effector trajectories in two FTL motion trials are compared to confirm the robot's repeatable behavior. Finally, we demonstrate the robot's operation on a 3D-printed spinal cord phantom model.

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An FBG-based Stiffness Estimation Sensor for In-vivo Diagnostics

In-vivo tissue stiffness identification can be useful in pulmonary fibrosis diagnostics and minimally invasive tumor identification, among many other applications. In this work, we propose a palpation-based method for tissue stiffness estimation that uses a sensorized beam buckled onto the surface of a tissue. Fiber Bragg Gratings (FBGs) are used in our sensor as a shape-estimation modality to get real-time beam shape, even while the device is not visually monitored. A mechanical model is developed to predict the behavior of a buckling beam and is validated using finite element analysis and bench-top testing with phantom tissue samples (made of PDMS and PA-Gel). Bench-top estimations were conducted and the results were compared with the actual stiffness values. Mean RMSE and standard deviation (from the actual stiffnesses) values of 413.86 KPa and 313.82 KPa were obtained. Estimations for softer samples were relatively closer to the actual values. Ultimately, we used the stiffness sensor within a mock concentric tube robot as a demonstration of \textit{in-vivo} sensor feasibility. Bench-top trials with and without the robot demonstrate the effectiveness of this unique sensing modality in \textit{in-vivo} applications.

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