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Ping Ma

Publications and source records attributed to Ping Ma.

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Knowledge Cascade: Reverse Knowledge Distillation on Nonparametric Multivariate Functional Estimation

As machine learning models and datasets continue to grow, developing complex models has become increasingly computationally demanding. Knowledge distillation reduces deployment cost by compressing a large, well-trained teacher model into a compact student model, but it does not address settings where constructing the teacher itself is the bottleneck. Motivated by this challenge, we introduce Knowledge Cascade (KCas), a reverse knowledge distillation framework that uses information from a small, inexpensive student model to guide the development of a more complex teacher model. Although this direction is counterintuitive because the teacher typically has greater representational capacity, we show that student-to-teacher transfer can be principled when supported by statistical scaling relationships. We first develop KCas for nonparametric multivariate functional estimation in reproducing kernel Hilbert spaces via smoothing splines, where selecting multiple smoothing parameters is a major computational bottleneck. KCas transfers student-selected smoothing parameters to the full-sample regime through asymptotic scaling laws, substantially reducing computational cost for high-dimensional and large-scale datasets while retaining theoretical guarantees. Beyond smoothing splines, we illustrate the same principle through kernel density estimation and deep learning hyperparameter transfer. Simulations and real-data experiments show that KCas achieves substantial computational savings while maintaining strong statistical performance, and can sometimes outperform the corresponding full-sample procedure.

stat.ME

Confidence-Aware Automated Assessment of Student-Drawn Scientific Models

Student-generated drawings are widely used in science education to assess learners' conceptual understanding in modeling-based tasks aligned with the Next Generation Science Standards (NGSS). However, scoring such drawings requires expert human judgment to interpret complex visual representations, making large-scale assessment costly to implement and sustain in classroom settings. In this work, we study automated scoring of student-generated scientific drawings using a vision-based model. We evaluate a Vision Transformer (ViT) with parameter-efficient adaptation and propose a confidence-aware scoring framework that derives response-level confidence from test-time predictive distributions. This confidence signal enables selective automation by scoring high-confidence responses automatically while deferring uncertain cases for human review. Experiments on six NGSS-aligned middle school assessment items show that the proposed approach improves scoring reliability while supporting a practical trade-off between automated coverage and scoring risk, highlighting the value of confidence-aware methods for trustworthy educational assessment.

cs.AI

Multi-Teacher Knowledge Distillation via Teacher-Informed Mixture Priors

Knowledge distillation is a powerful method for model compression, enabling the efficient deployment of complex deep learning models (teachers), including large language models. However, its underlying statistical mechanisms remain unclear, and uncertainty evaluation is often overlooked, especially in real-world scenarios requiring diverse teacher expertise. To address these challenges, we introduce \textit{Multi-Teacher Bayesian Knowledge Distillation} (MT-BKD), where a distilled student model learns from multiple teachers within the Bayesian framework. Our approach leverages Bayesian inference to capture inherent uncertainty in the distillation process. We introduce a teacher-informed prior, integrating external knowledge from teacher models and task-specific training data, offering better generalization, robustness, and scalability. Additionally, an entropy-based weighting mechanism adaptively adjusts each teacher's influence, allowing the student to combine multiple sources of expertise effectively. MT-BKD enhances the interpretability of the student model's learning process, improves predictive accuracy, and provides uncertainty quantification. We validate MT-BKD on both synthetic and real-world tasks, including protein subcellular location prediction and image classification. Our experiments show improved performance and robust uncertainty quantification, highlighting the strengths of our MT-BKD framework.

stat.ME

NeuroMAS: Multi-Agent Systems as Neural Networks with Joint Reinforcement Learning

Multi-agent language systems are often built as hand-designed workflows, where agents are assigned semantic roles and communication protocols are specified in advance. We propose NeuroMAS, a method that first treats a multi-agent language system as a trainable and scalable neural-network-like architecture with LLM agents as nodes and intermediate textual signals as edges. In NeuroMAS, agent nodes are role-free but structure-aware: the topology only determines how information can flow in general, while reinforcement learning training determines how nodes communicate, specialize, and coordinate. This formulation shifts multi-agent design from workflow engineering toward architecture design, where depth, width, connectivity, and growth protocol become scalable sources of capability. Further, we provide a theoretical perspective showing why such modular textual computation is more parameter-efficient when tasks admit hierarchical decompositions. Experiments show that NeuroMAS improves significantly over both inference-time and trained multi-agent baselines. We further find that organizational scaling is path-dependent: larger systems can be challenging to train from scratch, but become feasible when grown progressively from smaller trained systems. These results suggest that learned neural multi-agent systems are a promising scaling axis for LLMs.

cs.AI

Wahkon: A Statistically Principled Deep RKHS Superposition Network

Deep learning excels at prediction but often lacks finite-sample guarantees and calibrated uncertainty; RKHS (Reproducing Kernel Hilbert Space)-based methods provide those guarantees but struggle to adapt in high dimensions. We propose Wahkon, a deep RKHS superposition network that unifies Kolmogorov's superposition principle with RKHS regularization in the smoothing-spline tradition of Wahba. This yields a finite-dimensional deep representer theorem that makes training tractable and provides explicit layerwise complexity control. We show the penalized estimator is exactly the MAP (maximum a posteriori) estimate under a hierarchical Gaussian-process prior, extending the spline/GP duality to deep compositions. Using metric-entropy arguments, we establish minimax-optimal convergence rates under mild smoothness and clarify how depth and width trade off with regularity. Empirically, Wahkon outperforms multilayer perceptrons, Neural Tangent Kernels, and Kolmogorov--Arnold Networks across simulation benchmarks and a single-cell CITE-seq study. By unifying Kolmogorov's superposition principle with RKHS regularization, Wahkon delivers accuracy, interpretability, and statistical rigor in a single framework.

stat.ME

Quantum Statistical Bootstrap

The bootstrap is a foundational tool in statistical inference, but its classical implementation relies on Monte Carlo resampling, introducing approximation error and incurring high computational cost -- especially for large datasets and complex models. We present the Quantum Bootstrap (QBOOT), a quantum algorithm that computes the ideal bootstrap estimate exactly by encoding all possible resamples in quantum superposition, evaluating the target statistic in parallel, and extracting the aggregate via quantum amplitude estimation. Under mild circuit efficiency assumptions, QBOOT achieves a near-quadratic speedup over the classical bootstrap in approximating the ideal estimator, independent of the statistic or underlying distribution. We provide a rigorous theoretical analysis of its statistical error properties -- addressing a gap in the quantum algorithms literature -- and validate our results through experiments on the IBM quantum simulator for the sample mean problem. Our findings demonstrate that QBOOT preserves the asymptotic properties of the ideal bootstrap while substantially improving computational efficiency and precision, establishing a scalable and principled framework for quantum statistical inference.

stat.CO

A Single Revision Step Improves Token-Efficient LLM Reasoning

Large language models (LLMs) achieve higher accuracy on challenging reasoning tasks by scaling test-time compute through multiple trajectory sampling. However, standard aggregation methods like majority voting or individual confidence-based filtering face a fundamental "blind spot": they evaluate each trace in isolation. As problems scale in difficulty, models often generate hallucinated paths that exhibit misleadingly high confidence, causing the true solution to be suppressed by a narrow margin in traditional voting. We ask: can we enable traces to "peer-review" each other to resolve these near-miss errors? We introduce Packet-Conditioned Revision (PACER), a training-free, inference-only framework that enables reasoning traces to revise their conclusions through a structured coordination step. After a preliminary screening of generated traces, PACER constructs a compact consensus packet containing (i) unique candidate answers, (ii) their aggregated confidence scores, and (iii) representative reasoning summaries for each candidate answer. Individual traces then perform a targeted self-review conditioned on this packet, allowing them to identify specific logical junctions where they diverged from the broader consensus and pivot if their original reasoning is found to be flawed. Final predictions are obtained via confidence-weighted voting over these revised trajectories. On challenging competitive math benchmarks such as AIME and BRUMO, PACER matches or exceeds the accuracy of 256-sample majority voting, significantly outperforming raw ensemble baselines by transforming simple consensus into a collaborative logical refinement process.

cs.LG

Generalizable and Efficient Automated Scoring with a Knowledge-Distilled Multi-Task Mixture-of-Experts

Automated scoring of written constructed responses typically relies on separate models per task, straining computational resources, storage, and maintenance in real-world education settings. We propose UniMoE-Guided, a knowledge-distilled multi-task Mixture-of-Experts (MoE) approach that transfers expertise from multiple task-specific large models (teachers) into a single compact, deployable model (student). The student combines (i) a shared encoder for cross-task representations, (ii) a gated MoE block that balances shared and task-specific processing, and (iii) lightweight task heads. Trained with both ground-truth labels and teacher guidance, the student matches strong task-specific models while being far more efficient to train, store, and deploy. Beyond efficiency, the MoE layer improves transfer and generalization: experts develop reusable skills that boost cross-task performance and enable rapid adaptation to new tasks with minimal additions and tuning. On nine NGSS-aligned science-reasoning tasks (seven for training/evaluation and two held out for adaptation), UniMoE-Guided attains performance comparable to per-task models while using $\sim$6$\times$ less storage than maintaining separate students, and $87\times$ less than the 20B-parameter teacher. The method offers a practical path toward scalable, reliable, and resource-efficient automated scoring for classroom and large-scale assessment systems.

cs.LG

DCMM-Transformer: Degree-Corrected Mixed-Membership Attention for Medical Imaging

Medical images exhibit latent anatomical groupings, such as organs, tissues, and pathological regions, that standard Vision Transformers (ViTs) fail to exploit. While recent work like SBM-Transformer attempts to incorporate such structures through stochastic binary masking, they suffer from non-differentiability, training instability, and the inability to model complex community structure. We present DCMM-Transformer, a novel ViT architecture for medical image analysis that incorporates a Degree-Corrected Mixed-Membership (DCMM) model as an additive bias in self-attention. Unlike prior approaches that rely on multiplicative masking and binary sampling, our method introduces community structure and degree heterogeneity in a fully differentiable and interpretable manner. Comprehensive experiments across diverse medical imaging datasets, including brain, chest, breast, and ocular modalities, demonstrate the superior performance and generalizability of the proposed approach. Furthermore, the learned group structure and structured attention modulation substantially enhance interpretability by yielding attention maps that are anatomically meaningful and semantically coherent.

cs.CV

Online Sequential Leveraging Sampling Method for Streaming Autoregressive Time Series with Application to Seismic Data

Seismic data contain complex temporal information that arrives at high speed and has a large, even potentially unbounded volume. The explosion of temporally correlated streaming data from advanced seismic sensors poses analytical challenges due to its sheer volume and real-time nature. Sampling, or data reduction, is a natural yet powerful tool for handling large streaming data while balancing estimation accuracy and computational cost. Currently, data reduction methods and their statistical properties for streaming data, especially streaming autoregressive time series, are not well-studied in the literature. In this article, we propose an online leverage-based sequential data reduction algorithm for streaming autoregressive time series with application to seismic data. The proposed Sequential Leveraging Sampling (SLS) method selects only one consecutively recorded block from the data stream for inference. While the starting point of the SLS block is chosen using a random mechanism based on streaming leverage scores of data, the block size is determined by a sequential stopping rule. The SLS block offers efficient sample usage, as evidenced by our results confirming asymptotic normality for the normalized least squares estimator in both linear and nonlinear autoregressive settings. The SLS method is applied to two seismic datasets: the 2023 Turkey-Syria earthquake doublet data on the macroseismic scale and the Oklahoma seismic data on the microseismic scale. We demonstrate the ability of the SLS method to efficiently identify seismic events and elucidate their intricate temporal dependence structure. Simulation studies are presented to evaluate the empirical performance of the SLS method.

stat.ME

Alignment and Safety in Large Language Models: Safety Mechanisms, Training Paradigms, and Emerging Challenges

Due to the remarkable capabilities and growing impact of large language models (LLMs), they have been deeply integrated into many aspects of society. Thus, ensuring their alignment with human values and intentions has emerged as a critical challenge. This survey provides a comprehensive overview of practical alignment techniques, training protocols, and empirical findings in LLM alignment. We analyze the development of alignment methods across diverse paradigms, characterizing the fundamental trade-offs between core alignment objectives. Our analysis shows that while supervised fine-tuning enables basic instruction-following, preference-based methods offer more flexibility for aligning with nuanced human intent. We discuss state-of-the-art techniques, including Direct Preference Optimization (DPO), Constitutional AI, brain-inspired methods, and alignment uncertainty quantification (AUQ), highlighting their approaches to balancing quality and efficiency. We review existing evaluation frameworks and benchmarking datasets, emphasizing limitations such as reward misspecification, distributional robustness, and scalable oversight. We summarize strategies adopted by leading AI labs to illustrate the current state of practice. We conclude by outlining open problems in oversight, value pluralism, robustness, and continuous alignment. This survey aims to inform both researchers and practitioners navigating the evolving landscape of LLM alignment.

cs.AI

S2MNet: Speckle-To-Mesh Net for Three-Dimensional Cardiac Morphology Reconstruction via Echocardiogram

Echocardiogram is the most commonly used imaging modality in cardiac assessment duo to its non-invasive nature, real-time capability, and cost-effectiveness. Despite its advantages, most clinical echocardiograms provide only two-dimensional views, limiting the ability to fully assess cardiac anatomy and function in three dimensions. While three-dimensional echocardiography exists, it often suffers from reduced resolution, limited availability, and higher acquisition costs. To overcome these challenges, we propose a deep learning framework S2MNet that reconstructs continuous and high-fidelity 3D heart models by integrating six slices of routinely acquired 2D echocardiogram views. Our method has three advantages. First, our method avoid the difficulties on training data acquasition by simulate six of 2D echocardiogram images from corresponding slices of a given 3D heart mesh. Second, we introduce a deformation field-based method, which avoid spatial discontinuities or structural artifacts in 3D echocardiogram reconstructions. We validate our method using clinically collected echocardiogram and demonstrate that our estimated left ventricular volume, a key clinical indicator of cardiac function, is strongly correlated with the doctor measured GLPS, a clinical measurement that should demonstrate a negative correlation with LVE in medical theory. This association confirms the reliability of our proposed 3D construction method.

eess.IV

Knowledge Distillation and Dataset Distillation of Large Language Models: Emerging Trends, Challenges, and Future Directions

The exponential growth of Large Language Models (LLMs) continues to highlight the need for efficient strategies to meet ever-expanding computational and data demands. This survey provides a comprehensive analysis of two complementary paradigms: Knowledge Distillation (KD) and Dataset Distillation (DD), both aimed at compressing LLMs while preserving their advanced reasoning capabilities and linguistic diversity. We first examine key methodologies in KD, such as task-specific alignment, rationale-based training, and multi-teacher frameworks, alongside DD techniques that synthesize compact, high-impact datasets through optimization-based gradient matching, latent space regularization, and generative synthesis. Building on these foundations, we explore how integrating KD and DD can produce more effective and scalable compression strategies. Together, these approaches address persistent challenges in model scalability, architectural heterogeneity, and the preservation of emergent LLM abilities. We further highlight applications across domains such as healthcare and education, where distillation enables efficient deployment without sacrificing performance. Despite substantial progress, open challenges remain in preserving emergent reasoning and linguistic diversity, enabling efficient adaptation to continually evolving teacher models and datasets, and establishing comprehensive evaluation protocols. By synthesizing methodological innovations, theoretical foundations, and practical insights, our survey charts a path toward sustainable, resource-efficient LLMs through the tighter integration of KD and DD principles.

cs.CL

Efficient Multi-Task Inferencing: Model Merging with Gromov-Wasserstein Feature Alignment

Automatic scoring of student responses enhances efficiency in education, but deploying a separate neural network for each task increases storage demands, maintenance efforts, and redundant computations. To address these challenges, this paper introduces the Gromov-Wasserstein Scoring Model Merging (GW-SMM) method, which merges models based on feature distribution similarities measured via the Gromov-Wasserstein distance. Our approach begins by extracting features from student responses using individual models, capturing both item-specific context and unique learned representations. The Gromov-Wasserstein distance then quantifies the similarity between these feature distributions, identifying the most compatible models for merging. Models exhibiting the smallest pairwise distances, typically in pairs or trios, are merged by combining only the shared layers preceding the classification head. This strategy results in a unified feature extractor while preserving separate classification heads for item-specific scoring. We validated our approach against human expert knowledge and a GPT-o1-based merging method. GW-SMM consistently outperformed both, achieving a higher micro F1 score, macro F1 score, exact match accuracy, and per-label accuracy. The improvements in micro F1 and per-label accuracy were statistically significant compared to GPT-o1-based merging (p=0.04, p=0.01). Additionally, GW-SMM reduced storage requirements by half without compromising much accuracy, demonstrating its computational efficiency alongside reliable scoring performance.

cs.CL

Large Language Models for Bioinformatics

With the rapid advancements in large language model (LLM) technology and the emergence of bioinformatics-specific language models (BioLMs), there is a growing need for a comprehensive analysis of the current landscape, computational characteristics, and diverse applications. This survey aims to address this need by providing a thorough review of BioLMs, focusing on their evolution, classification, and distinguishing features, alongside a detailed examination of training methodologies, datasets, and evaluation frameworks. We explore the wide-ranging applications of BioLMs in critical areas such as disease diagnosis, drug discovery, and vaccine development, highlighting their impact and transformative potential in bioinformatics. We identify key challenges and limitations inherent in BioLMs, including data privacy and security concerns, interpretability issues, biases in training data and model outputs, and domain adaptation complexities. Finally, we highlight emerging trends and future directions, offering valuable insights to guide researchers and clinicians toward advancing BioLMs for increasingly sophisticated biological and clinical applications.

q-bio.QM

A Systematic Assessment of OpenAI o1-Preview for Higher Order Thinking in Education

As artificial intelligence (AI) continues to advance, it demonstrates capabilities comparable to human intelligence, with significant potential to transform education and workforce development. This study evaluates OpenAI o1-preview's ability to perform higher-order cognitive tasks across 14 dimensions, including critical thinking, systems thinking, computational thinking, design thinking, metacognition, data literacy, creative thinking, abstract reasoning, quantitative reasoning, logical reasoning, analogical reasoning, and scientific reasoning. We used validated instruments like the Ennis-Weir Critical Thinking Essay Test and the Biological Systems Thinking Test to compare the o1-preview's performance with human performance systematically. Our findings reveal that o1-preview outperforms humans in most categories, achieving 150% better results in systems thinking, computational thinking, data literacy, creative thinking, scientific reasoning, and abstract reasoning. However, compared to humans, it underperforms by around 25% in logical reasoning, critical thinking, and quantitative reasoning. In analogical reasoning, both o1-preview and humans achieved perfect scores. Despite these strengths, the o1-preview shows limitations in abstract reasoning, where human psychology students outperform it, highlighting the continued importance of human oversight in tasks requiring high-level abstraction. These results have significant educational implications, suggesting a shift toward developing human skills that complement AI, such as creativity, abstract reasoning, and critical thinking. This study emphasizes the transformative potential of AI in education and calls for a recalibration of educational goals, teaching methods, and curricula to align with an AI-driven world.

cs.CY

Semi-supervised Concept Bottleneck Models

Concept Bottleneck Models (CBMs) have garnered increasing attention due to their ability to provide concept-based explanations for black-box deep learning models while achieving high final prediction accuracy using human-like concepts. However, the training of current CBMs is heavily dependent on the precision and richness of the annotated concepts in the dataset. These concept labels are typically provided by experts, which can be costly and require significant resources and effort. Additionally, concept saliency maps frequently misalign with input saliency maps, causing concept predictions to correspond to irrelevant input features - an issue related to annotation alignment. To address these limitations, we propose a new framework called SSCBM (Semi-supervised Concept Bottleneck Model). Our SSCBM is suitable for practical situations where annotated data is scarce. By leveraging joint training on both labeled and unlabeled data and aligning the unlabeled data at the concept level, we effectively solve these issues. We proposed a strategy to generate pseudo labels and an alignment loss. Experiments demonstrate that our SSCBM is both effective and efficient. With only 10% labeled data, our model's concept and task accuracy on average across four datasets is only 2.44% and 3.93% lower, respectively, compared to the best baseline in the fully supervised learning setting.

cs.CV

Non-Destructive Peat Analysis using Hyperspectral Imaging and Machine Learning

Peat, a crucial component in whisky production, imparts distinctive and irreplaceable flavours to the final product. However, the extraction of peat disrupts ancient ecosystems and releases significant amounts of carbon, contributing to climate change. This paper aims to address this issue by conducting a feasibility study on enhancing peat use efficiency in whisky manufacturing through non-destructive analysis using hyperspectral imaging. Results show that shot-wave infrared (SWIR) data is more effective for analyzing peat samples and predicting total phenol levels, with accuracies up to 99.81%.

cs.CV