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Qiegen Liu

Publications and source records attributed to Qiegen Liu.

At least 19 recordsLinked to original sources

LaminoDiff: Generative Computed Laminography via Near-Isotropic Spectral Supervision and Anisotropic Geometry

Computed Laminography (CL) is widely used for nondestructive inspection of extended planar objects, but its restricted angular coverage produces an anisotropic point spread function, missing-cone spectral incompleteness, and severe aliasing with interlayer leakage. This paper presents LaminoDiff, a physics-constrained diffusion framework for CL reconstruction. During training, a CT-derived near-isotropic supervision target is reconstructed from full-angle Computed Tomography (CT) projections physically degraded to match CL detector noise and focal-spot blur while retaining full angular coverage; it is withheld from inference. At inference, the reverse process uses only the CL observation. An Anisotropic Representation (AR) constructs depth-aware channels from three adjacent slices: a neighbor average, a center-neighbor residual, and the retained current slice, followed by directional in-plane feature extraction. Experiments on simulated and real multilayer printed circuit board data, including ball grid array and high-frequency stub samples, show that LaminoDiff improves artifact suppression, edge preservation, and depth stratification over analytic Feldkamp--Davis--Kress and representative learning-based baselines.

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Diffusion-Encoding Gaussian Field for Joint k-q dMRI Reconstruction

Diffusion MRI requires repeated k-space acquisitions over multiple diffusion-encoding directions, making acquisition time dependent on both spatial and angular sampling. Existing joint k-q methods either associate directional parameters with fixed voxels or separate spatial reconstruction from angular completion. However, diffusion-weighted images acquired under different directions share the same anatomical organization, while their local signal intensities vary with diffusion encoding. Existing formulations do not fully exploit the complementarity between shared anatomy and direction-dependent signal variation. Consequently, residual spatial errors may be misinterpreted as genuine angular variation and propagated to unobserved directions. We propose a subject-specific spatial-angular Gaussian field for self-supervised joint k-q dMRI reconstruction. Shared 3D Gaussian primitives provide local spatial support, with each primitive carrying a continuous q-conditioned tensor-residual response. The signal at each location is synthesized from multiple overlapping primitive responses, coupling neighboring spatial regions and diffusion directions. The field is progressively optimized from undersampled k-space measurements of observed directions, without fully sampled targets or held-out-direction supervision. Experiments on three HCP diffusion shells under multiple acceleration settings demonstrated consistent improvements in missing-direction DWI reconstruction, tensor-derived metrics, and principal diffusion orientation estimation.

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Physics-Driven Independent Pair Generation for Iterative Self-Supervised Low-Dose CT Denoising

Low-dose computed tomography (LDCT) measurements contain mixed Poisson-Gaussian noise. However, most self-supervised methods rely on generic image statistics and do not explicitly model this noise, which may limit their ability to effectively suppress realistic LDCT noise. To address this issue, we propose a physics-driven framework with cross-domain iteration for self-supervised LDCT denoising. The proposed framework proceeds in three main steps. First, a learned sinogram prior and the LDCT noise model guide posterior inference of photon counts, enabling separation of the Poisson and Gaussian components. Second, the separated Poisson and Gaussian components are respectively processed by binomial thinning and Gaussian data thinning to construct two branches, and residual scaling matches each branch's noise level to that of the observation, yielding a training pair with approximately independent noise realizations from one low-dose measurement. Finally, the pair is used to train an image-domain network whose forward-projected outputs update the prior. Through cross-domain iteration, the prior and the training pair are progressively refined while maintaining consistency with CT acquisition physics. Experiments on simulated data from AAPM, LIDC-IDRI, and LoDoPaB-CT and on real LDCT data show consistent gains over the evaluated self-supervised baselines across dose levels, with performance comparable to the evaluated supervised baseline.

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Shared-Structure 4D Spectral Gaussian Representation for Sparse-View Spectral CT Reconstruction

Sparse-view spectral computed tomography (CT) reconstructs energy-resolved attenuation volumes from limited projection views, requiring simultaneous handling of angular undersampling and spectral coupling. We propose a SharedStructure 4D Spectral Gaussian Representation (4D-SG) that learns shared Gaussian geometry from full spectrum structural projections and uses a Gaussian-wise Spectral Density Curve Network (GSC-Net) to predict Gaussian raw density transformations. This factorization separates shared spatial structure from spectral attenuation variation, avoids independent channel geometry optimization, and establishes a continuous 4D-SG representation from discrete spectral measurements for unobserved spectral channel queries. Experiments on six synthesized, simulated projection, and real projection datasets with 50 views demonstrate the best average performance. Compared with the strongest Gaussian baseline, 4D-SG improves PSNR from 35.56 dB to 36.61 dB, increases SSIM from 0.909 to 0.914, and reduces LPIPS from 0.208 to 0.194, demonstrating its effectiveness for sparse-view spectral CT reconstruction.

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K-space Gaussian Representation for Parallel MRI

Accelerated magnetic resonance imaging (MRI) aims to recover the k-space signal from acquired measurements, where accurate estimation of missing samples is essential for high-fidelity reconstruction. Existing k-space reconstruction methods estimate missing samples through interpolation operators or structure priors defined on discrete sampling grids. Although these formulations effectively exploit local interpolation relationships and global k-space redundancy, they reconstruct only discrete frequency coefficients and therefore do not explicitly model the underlying continuous signal. To overcome this limitation, we propose K-space Gaussian Representation (KGR), the first explicit continuous representation formulated directly in the native k-space domain. Rather than estimating unknown samples on discrete grids, KGR parameterizes the continuous signal using Gabor-Gaussian primitives with shared spatial geometry, yielding a compact representation that naturally preserves inter-coil correlations. Because unconstrained continuous fitting does not necessarily satisfy the intrinsic structural properties of multi-coil signal, the estimated representation is projected onto a low-rank manifold to enforce the algebraic constraints arising from smoothly varying phase and coil redundancy. A frequency-adaptive fitting strategy accommodates the heterogeneous characteristics of different k-space regions. Comprehensive validation across multiple datasets and sampling schemes shows consistent improvements over representative reconstruction baselines in both quantitative metrics and visual quality. These results suggest that explicit continuous parameterization of native k-space provides a principled framework for integrating continuous signal modeling with structured low-rank reconstruction.

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WHU-PCPR: A cross-platform heterogeneous point cloud dataset for place recognition in complex urban scenes

Point Cloud-based Place Recognition (PCPR) demonstrates considerable potential in applications such as autonomous driving, robot localization and navigation, and map update. In practical applications, point clouds used for place recognition are often acquired from different platforms and LiDARs across varying scene. However, existing PCPR datasets lack diversity in scenes, platforms, and sensors, which limits the effective development of related research. To address this gap, we establish WHU-PCPR, a cross-platform heterogeneous point cloud dataset designed for place recognition. The dataset differentiates itself from existing datasets through its distinctive characteristics: 1) cross-platform heterogeneous point clouds: collected from survey-grade vehicle-mounted Mobile Laser Scanning (MLS) systems and low-cost Portable helmet-mounted Laser Scanning (PLS) systems, each equipped with distinct mechanical and solid-state LiDAR sensors. 2) Complex localization scenes: encompassing real-time and long-term changes in both urban and campus road scenes. 3) Large-scale spatial coverage: featuring 82.3 km of trajectory over a 60-month period and an unrepeated route of approximately 30 km. Based on WHU-PCPR, we conduct extensive evaluation and in-depth analysis of several representative PCPR methods, and provide a concise discussion of key challenges and future research directions. The dataset and benchmark code are available at https://github.com/zouxianghong/WHU-PCPR.

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Coexistence and manipulation of multiple singularities in a reconfigurable non-Hermitian metasurface

Non-Hermitian frameworks extend conventional Hermitian physics, offering a powerful paradigm for describing open systems. Central to this field are various singularities within the complex parameter space, such as exceptional points (EPs) and scattering zeros, which dictate exotic physical behaviors. As research shifts from isolated singularities toward multi-singularity interactions, conventional planar metasurfaces remain constrained by limited tuning dimensions. Here, we propose a mirror-coupled design that maps a metasurface into a quasi-high-dimensional parameter space. By employing a metallic plane to generate image resonators, this scheme multiplies the system degrees of freedom without increasing the number of physical resonators. Its implementation on a reconfigurable platform integrated with PIN diodes yields the coexistence and manipulation of an EP and multiple reflection zeros. Through simulations and microwave experiments, we characterize the dynamic evolution of these singularities and exploit their synergistic effects for two distinct applications. First, for tunable absorption, multiple reflection zeros are spectrally coordinated to achieve a near-perfect absorption band exceeding $99.9\%$ across the X-band, thereby dynamically suppressing target scattering. Second, for enhanced sensing, a reflection zero couples with the EP to form a hybrid singularity. This hybrid state inherits the power-law sensitivity of the EP while substantially boosting robustness against fluctuations, resolving the conventional trade-off between sensitivity and stability and simplifying detection to direct peak tracking rather than complex multimode eigenvalue fitting. Our work provides a general methodology to circumvent parameter competition among non-Hermitian singularities, opening new avenues for multifunctional metadevices across the electromagnetic spectrum.

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High-dimensional Embedding Prior for Noisy K-space Domain MRIReconstruction

Magnetic resonance imaging (MRI) reconstruction under realistic acquisition conditions can be fundamentally viewed as estimating the underlying k-space distribution from incomplete and noise-corrupted measurements. While diffusion models have recently shown strong potential as generative prior for inverse problems,existingapproachesstruggletohandlenoisyreconstruction settings, especially when operating directly in k-space domain. In this work, we propose a unified high-dimensional k-space reconstruction framework tailored for noisy inverse problems, whichenhancesdiffusion-based solversthroughrepresentation lifting.Ratherthanmodifyingthe underlying optimization procedures, the proposed framework augments the data representation space, enabling existing diffusion-based solvers to operate on enriched k-space embeddings with improved expressiveness. Extensive experiments on both in-house and public datasets across varying noise levels and undersampled factors demonstrate that the proposed frame work consistently improves reconstruction quality for multiple diffusion-based inverse solvers. Notably, the largest gains are observed in high-noise regimes, which is consistent with our theoretical analysis of error propagation under high-dimensional representation. These results suggest that high-dimensional representation provides a general and model-agnostic mechanism for improving diffusion-based MRI reconstruction in noisy settings, offering a new perspective on robust k-space generative modeling for practical inverse problems. The code will be available at https://github.com/yqx7150/HEP-MRIRec.

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Iterative Diffusion-Refined Neural Attenuation Fields for Multi-Source Stationary CT Reconstruction: NAF Meets Diffusion Model

Multi-source stationary computed tomography (CT) has recently attracted attention for its ability to achieve rapid image reconstruction, making it suitable for time-sensitive clinical and industrial applications. However, practical systems are often constrained by ultra-sparse-view sampling, which significantly degrades reconstruction quality. Traditional methods struggle under ultra-sparse-view settings, where interpolation becomes inaccurate and the resulting reconstructions are unsatisfactory. To address this challenge, this study proposes Diffusion-Refined Neural Attenuation Fields (Diff-NAF), an iterative framework tailored for multi-source stationary CT under ultra-sparse-view conditions. Diff-NAF combines a Neural Attenuation Field representation with a dual-branch conditional diffusion model. The process begins by training an initial NAF using ultra-sparse-view projections. New projections are then generated through an Angle-Prior Guided Projection Synthesis strategy that exploits inter view priors, and are subsequently refined by a Diffusion-driven Reuse Projection Refinement Module. The refined projections are incorporated as pseudo-labels into the training set for the next iteration. Through iterative refinement, Diff-NAF progressively enhances projection completeness and reconstruction fidelity under ultra-sparse-view conditions, ultimately yielding high-quality CT reconstructions. Experimental results on multiple simulated 3D CT volumes and real projection data demonstrate that Diff-NAF achieves the best performance under ultra-sparse-view conditions.

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FrequencyCT: Frequency Domain Self-supervised Low-dose CT Denoising

Despite extensive research on computed tomography (CT) denoising, few studies exploit projection-domain data characteristics to mitigate noise correlation. To bridge this gap, this work proposes FrequencyCT, the first zero-shot self-supervised method for pseudo-sample generation in the frequency domain for low-dose CT denoising. Specifically, by exploiting the distinct frequency-domain distributions of noise and true signal, a regional low-frequency anchoring technique is proposed. Applying phase-preserving noise and mask perturbations to the high-frequency region generates pseudo-samples for self-supervision. Driven by the exponential correlation between noise variance of noisy projections and the underlying true signal, consistent data truncation is applied to the generated samples to stabilize optimization gradients. Evaluation results on multiple public and real datasets confirm the clinical application potential of this research, which provides an innovative perspective for the field of denoising. The code is available at: https://github.com/yqx7150/FrequencyCT.

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Residual Gaussian Splatting for Ultra Sparse-View CBCT Reconstruction

While 3D Gaussian splatting (3DGS) offers explicit and efficient scene representations for cone-beam computed tomography reconstruction, conventional photometric optimization inherently suffers from spectral bias under ultra sparse-view conditions, leading to over-smoothing and a loss of high-frequency anatomical details. Since wavelet transforms provide rich high-frequency information and have been widely utilized to enhance sparse reconstruction, this work integrates wavelet multi-resolution analysis with 3DGS. To circumvent the mathematical mismatch between the strict non-negativity of physical X-ray attenuation and the bipolar nature of high-frequency wavelet coefficients, we propose Residual Gaussian Splatting (RGS). Methodologically, we introduce a spectrally-decoupled Gaussian representation that stratifies the volumetric field into a geometric base component and a residual detail component. This decomposition systematically transforms explicit high-frequency fitting into a physically consistent, implicit residual compensation task. Furthermore, we devise a spectral-spatial collaborative optimization strategy to coordinate the interplay between geometric anchoring and texture refinement, effectively preventing spectral crosstalk. Extensive experiments on clinical datasets demonstrate that RGS enables the reconstructed images to capture highly refined geometric textures. It successfully resolves the trade-off between artifact suppression and detail preservation, yielding superior visual fidelity in complex trabecular and vascular structures compared to existing neural rendering baselines.

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Flat optics for analog computing: from fundamental mechanisms to advanced meta-processors

As the explosive growth of visual data increasingly strains the latency and energy limits of conventional electronic computing, optical analog computing has re-emerged as a disruptive paradigm for zero-power, speed-of-light information processing. Propelled by the unprecedented wave-manipulation capabilities of optical metasurfaces, this field is undergoing a rapid transition from macroscopic physical optics to ultra-compact, on-chip meta-processors. This Review examines the fundamental mechanisms of metasurface-empowered optical computing spanning Fourier-domain, nonlocal spatial-domain, and interferometric architectures that perform mathematical operations, with a particular focus on spatial differentiation and edge detection as representative computing tasks. By emphasizing recent breakthroughs, we highlight the evolution of meta-processors from static, linear regimes to dynamically reconfigurable, nonlinear, and quantum-assisted multidimensional platforms. We also envision how the synergy of AI-driven inverse design and the integration of analog meta-front-ends with optical neural networks will synergistically revolutionize next-generation intelligent machine vision.

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Doubly resonant nonlinear metasurfaces enabling NIR-to-UV upconversion for reconfigurable Fourier optical processing

Fourier optical processing underpins optical information manipulation, yet extending such operations to short wavelengths within compact platforms remains challenging. Here, we address this challenge by embedding reconfigurable Fourier-domain processing within IR-to-UV upconversion in a doubly resonant nonlinear metasurface. When coherently illuminated at the Fourier plane with an image-bearing signal and a spatially structured pump, the metasurface generates UV images via degenerate four-wave mixing. Crucially, the spatial-frequency content of these upconverted images is selectively shaped by the tailored spectrum of the pump. To boost the efficiency of this nonlinear process, the metasurface is designed to simultaneously support a toroidal dipole bound state in the continuum and a magnetic dipole resonance, providing spectrally aligned and independently enhanced field localization for signal and pump beams, respectively. Building on this architecture, we experimentally demonstrate directional and continuously tunable filtering at the upconverted UV wavelengths. These results establish nonlinear metasurfaces as a versatile platform for Fourier optics and reconfigurable all-optical image processing.

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SCOUT: Fast Spectral CT Imaging in Ultra LOw-data Regimes via PseUdo-label GeneraTion

Noise and artifacts during computed tomography (CT) scans are a fundamental challenge affecting disease diagnosis. However, current methods either involve excessively long reconstruction times or rely on data-driven models for optimization, failing to adequately consider the valuable information inherent in the data itself, especially medical 3D data. This work proposes a reconstruction method under ultra-low raw data conditions, requiring no external data and avoiding lengthy pre-training processes. By leveraging spatial nonlocal similarity and the conjugate properties of the projection domain to generate pseudo-3D data for self-supervised training, high-fidelity results can be achieved in a very short time. Extensive experiments demonstrate that this method not only mitigates detector-induced ring artifacts but also exhibits unprecedented capabilities in detail recovery. This method provides a new paradigm for research using unlabeled raw projection data. Code is available at https://github.com/yqx7150/SCOUT.

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PLOT-CT: Pre-log Voronoi Decomposition Assisted Generation for Low-dose CT Reconstruction

Low-dose computed tomography (LDCT) reconstruction is fundamentally challenged by severe noise and compromised data fidelity under reduced radiation exposure. Most existing methods operate either in the image or post-log projection domain, which fails to fully exploit the rich structural information in pre-log measurements while being highly susceptible to noise. The requisite logarithmic transformation critically amplifies noise within these data, imposing exceptional demands on reconstruction precision. To overcome these challenges, we propose PLOT-CT, a novel framework for Pre-Log vOronoi decomposiTion-assisted CT generation. Our method begins by applying Voronoi decomposition to pre-log sinograms, disentangling the data into distinct underlying components, which are embedded in separate latent spaces. This explicit decomposition significantly enhances the model's capacity to learn discriminative features, directly improving reconstruction accuracy by mitigating noise and preserving information inherent in the pre-log domain. Extensive experiments demonstrate that PLOT-CT achieves state-of-the-art performance, attaining a 2.36dB PSNR improvement over traditional methods at the 1e4 incident photon level in the pre-log domain.

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GR-Diffusion: 3D Gaussian Representation Meets Diffusion in Whole-Body PET Reconstruction

Positron emission tomography (PET) reconstruction is a critical challenge in molecular imaging, often hampered by noise amplification, structural blurring, and detail loss due to sparse sampling and the ill-posed nature of inverse problems. The three-dimensional discrete Gaussian representation (GR), which efficiently encodes 3D scenes using parameterized discrete Gaussian distributions, has shown promise in computer vision. In this work, we pro-pose a novel GR-Diffusion framework that synergistically integrates the geometric priors of GR with the generative power of diffusion models for 3D low-dose whole-body PET reconstruction. GR-Diffusion employs GR to generate a reference 3D PET image from projection data, establishing a physically grounded and structurally explicit benchmark that overcomes the low-pass limitations of conventional point-based or voxel-based methods. This reference image serves as a dual guide during the diffusion process, ensuring both global consistency and local accuracy. Specifically, we employ a hierarchical guidance mechanism based on the GR reference. Fine-grained guidance leverages differences to refine local details, while coarse-grained guidance uses multi-scale difference maps to correct deviations. This strategy allows the diffusion model to sequentially integrate the strong geometric prior from GR and recover sub-voxel information. Experimental results on the UDPET and Clinical datasets with varying dose levels show that GR-Diffusion outperforms state-of-the-art methods in enhancing 3D whole-body PET image quality and preserving physiological details.

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Back to Physics: Operator-Guided Generative Paths for SMS MRI Reconstruction

Simultaneous multi-slice (SMS) imaging with in-plane undersampling enables highly accelerated MRI but yields a strongly coupled inverse problem with deterministic inter-slice interference and missing k-space data. Most diffusion-based reconstructions are formulated around Gaussian-noise corruption and rely on additional consistency steps to incorporate SMS physics, which can be mismatched to the operator-governed degradations in SMS acquisition. We propose an operator-guided framework that models the degradation trajectory using known acquisition operators and inverts this process via deterministic updates. Within this framework, we introduce an operator-conditional dual-stream interaction network (OCDI-Net) that explicitly disentangles target-slice content from inter-slice interference and predicts structured degradations for operator-aligned inversion, and we instantiate reconstruction as a two-stage chained inference procedure that performs SMS slice separation followed by in-plane completion. Experiments on fastMRI brain data and prospectively acquired in vivo diffusion MRI data demonstrate improved fidelity and reduced slice leakage over conventional and learning-based SMS reconstructions.

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FSP-Diff: Full-Spectrum Prior-Enhanced DualDomain Latent Diffusion for Ultra-Low-Dose Spectral CT Reconstruction

Spectral computed tomography (CT) with photon-counting detectors holds immense potential for material discrimination and tissue characterization. However, under ultra-low-dose conditions, the sharply degraded signal-to-noise ratio (SNR) in energy-specific projections poses a significant challenge, leading to severe artifacts and loss of structural details in reconstructed images. To address this, we propose FSP-Diff, a full-spectrum prior-enhanced dual-domain latent diffusion framework for ultra-low-dose spectral CT reconstruction. Our framework integrates three core strategies: 1) Complementary Feature Construction: We integrate direct image reconstructions with projection-domain denoised results. While the former preserves latent textural nuances amidst heavy noise, the latter provides a stable structural scaffold to balance detail fidelity and noise suppression. 2) Full-Spectrum Prior Integration: By fusing multi-energy projections into a high-SNR full-spectrum image, we establish a unified structural reference that guides the reconstruction across all energy bins. 3) Efficient Latent Diffusion Synthesis: To alleviate the high computational burden of high-dimensional spectral data, multi-path features are embedded into a compact latent space. This allows the diffusion process to facilitate interactive feature fusion in a lower-dimensional manifold, achieving accelerated reconstruction while maintaining fine-grained detail restoration. Extensive experiments on simulated and real-world datasets demonstrate that FSP-Diff significantly outperforms state-of-the-art methods in both image quality and computational efficiency, underscoring its potential for clinically viable ultra-low-dose spectral CT imaging.

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