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Sangjoon Park

Publications and source records attributed to Sangjoon Park.

At least 19 recordsLinked to original sources

RepConTUR: A Report-Conditioned Volumetric Multimodal Model for Abdominal Tumor Segmentation

Tumor delineation is required for radiotherapy planning, yet automatic segmentation is limited by errors, predominantly false positives, that distort dose and increase editing time. The radiology report accompanies the scan and localizes disease at the suborgan level, but existing text-promptable models condition on short referring phrases, and most operate in 2D. We present RepConTUR, a single native-3D early-fusion multimodal model that conditions volumetric abdominal tumor segmentation on the narrative report. We extend AbdomenAtlas 3.0 to a suborgan-level promptable segmentation dataset and generate report-based VQA pairs, yielding four report-derived tasks on the same annotations: referring segmentation (RES), report-grounded segmentation (GSEG), report generation (RRG), and visual question answering (VQA). We train RepConTUR, comprising a 3D CT encoder, an early-fusion language model, and a native-3D segmentation module, jointly on the four tasks. Across liver, kidney and pancreas, RepConTUR attains the highest Dice similarity coefficient (DSC), instance-wise precision, and detection F1 among the text-promptable baselines, and adding the report raises mean precision while leaving recall comparable. Against two vision-only specialists, nnU-Net and the report-supervised R-Super, RepConTUR attains the highest value on every in-domain metric for liver and pancreas and the highest mean DSC, recall, precision, and detection F1 over the four out-of-distribution public cohorts. Ablations indicate that conditioning on the narrative report raises detection F1 from 0.499 to 0.528 within the same model, that joint GSEG training raises RES F1 from 0.450 to 0.482, and that the native-3D segmentation module raises GSEG F1 from 0.139 to 0.528 over its 2D counterpart. Code is available at https://github.com/Oncosoft-Research/RepConTUR.

cs.CV↗

Explosive Synchronization in Inertial Kuramoto Models: Determining Resilience in Power Grids

Maintaining power-grid stability is essential for a sustainable energy supply. Using empirical power-grid data, we show that the inertial Kuramoto model with correlated powers and coupling strengths provides a relevant framework for analyzing explosive synchronization and grid stability. We identify two distinct synchronization pathways, initiated by population-driven or coupling-driven seed rotors, that yield different order-parameter behaviors. Inertia, in turn, determines whether the resulting seed clusters retain distinct angular velocities. Similar mechanisms govern recovery from external disturbances, linking power-grid resilience to these two nucleation pathways. Our findings provide a microscopic framework for understanding synchronization and recovery, with implications for stable power-grid operation.

nlin.AO↗

A Shy Voter Model: Entropy Flux in Opinion Formation

Some voters conceal their opinions, causing a mismatch between visible and private opinions in polls. Conventional voter models do not account for such concealment. Here, we introduce a shy voter model that incorporates a hidden state in addition to two visible states, as an extension of the conventional majority-rule voter model. The model exhibits continuous and hybrid transitions, yielding a rich phase diagram organized by the hidden fraction, i.e., the fraction of voters in the hidden state. For a large hidden fraction, the system undergoes a hybrid transition from the ordered state to the symmetric (disordered) state, whereas for a small hidden fraction, it exhibits a continuous transition, with a tricritical point separating the two regimes. Near criticality, both the order-parameter variance and the susceptibility diverge. The hidden fraction also governs the entropy flux, a quantity that is not directly observable in real-world situations. Thus, opinion concealment qualitatively reshapes opinion dynamics, while the present framework provides a basis for further extensions toward more realistic forms of social interactions.

physics.soc-ph↗

CoMMa: Contribution-Aware Medical Multi-Agents for Decentralized Oncology Decision Support

Recent multi-agent frameworks have shown promise for oncology decision support, yet most assume centralized data access and rely on prompt-based assignment, limiting their applicability in privacy-sensitive clinical settings. We propose Contribution-Aware Medical Multi-Agents (CoMMa), a decentralized LLM-agent framework where specialists operate on partitioned clinical data streams. Unlike prior approaches that share inputs across agents, CoMMa enforces data decentralization to include stronger role specialization and further enhances this via agent-specific finetuning. To enable reliable and interpretable coordination, we introduce a contribution-aware aggregation mechanism that replaces stochastic, narrative-based reasoning with deterministic embedding projections to approximate each agent's marginal utility. This yields explicit credit assignment over agents, providing a stable and interpretable decision pathway aligned with clinical requirements. We evaluate CoMMa on multiple oncology benchmarks, including real-world multidisciplinary tumor board datasets from large academic hospitals in North America and East Asia, as well as public datasets, demonstrating strong performance and generalization across heterogeneous clinical settings.

cs.AI↗

DuetMoE: Coupling Inter- and Intra-Subgroup Robustness for Fair Medical Image Analysis

As medical AI expands across diverse healthcare settings worldwide, equitable performance across patient populations is becoming essential to trustworthy clinical use. Fairness in medical image analysis is often evaluated through average performance across predefined subgroups, yet similar subgroup averages can conceal substantial variation among individual patients. Therefore, a reliable medical AI requires addressing two complementary objectives: \emph{inter-subgroup fairness}, which reduces performance disparities across groups, and \emph{intra-subgroup robustness}, which protects poorly served patients within each group. To jointly address these objectives, we propose \textbf{DuetMoE}, a subgroup-aware mixture-of-experts framework that couples group-level adaptation with patient-specific clinical guidance, enabling more reliable medical image analysis for individual patients. For settings without linked clinical records, we further introduce \textbf{DuetMoE+}, which retains subgroup-routed experts and incorporates a KL-constrained distributionally robust objective to address intra-subgroup robustness. We evaluate our methods on PI-CAI, radiotherapy, and Harvard-FairSeg. Across four evaluation settings, our methods lead in overall or equity-scaled performance, reduce the inter-subgroup mean Dice gap by up to $30.7\%$, and raise intra-subgroup 25th-percentile Dice by up to 11.5 points over the strongest reported baselines.

cs.CV↗

Migration Flows: Population Scaling and Heavy Tails

We show how migration between counties in different cities can explain both the population scaling of mean intercity flows and heavy-tailed intercity net-flow distributions. Density-dependent departure and arrival activities determine how mean flows scale with the populations of the origin and destination cities. We assume Gaussian county-pair net flows with standard deviations proportional to their mean directional flows. At a fixed correlation between county-pair net flows, their sum is Gaussian. Averaging this conditional Gaussian density over the correlation distribution can produce an intermediate power law with a Gaussian cutoff. We also present a stochastic model that generates the variance distribution used in this mixture.

cond-mat.stat-mech↗

Mixture of Multicenter Experts in Multimodal AI for Debiased Radiotherapy Target Delineation

Clinical decision-making reflects diverse strategies shaped by regional patient populations and institutional protocols. However, most existing medical artificial intelligence (AI) models are trained on highly prevalent data patterns, which reinforces biases and fails to capture the breadth of clinical expertise. Inspired by the recent advances in Mixture of Experts (MoE), we propose a Mixture of Multicenter Experts (MoME) framework to address AI bias in the medical domain without requiring data sharing across institutions. MoME integrates specialized expertise from diverse clinical strategies to enhance model generalizability and adaptability across medical centers. We validate this framework using a multimodal target volume delineation model for prostate cancer radiotherapy. With few-shot training that combines imaging and clinical notes from each center, the model outperformed baselines, particularly in settings with high inter-center variability or limited data availability. Furthermore, MoME enables model customization to local clinical preferences without cross-institutional data exchange, making it especially suitable for resource-constrained settings while promoting broadly generalizable medical AI.

eess.IV↗

AI-Driven Stabilization in Power Grids through Controlling Line Admittances

The global transition from traditional power plants to renewable energy sources introduces new challenges in grid stability, primarily because inverter-based technologies provide insufficient inertia. To address this, we introduce an artificial intelligence algorithm that autonomously stabilizes power grids by adaptively tuning admittance regulators in response to disturbances. This Adaptive Admittance Controller (AAC) algorithm not only stabilizes the system in real time but also identifies the best regulator locations, thereby unifying grid planning and real time control within a single framework. When tested on a real UK power grid, the AAC markedly reduces frequency deviations and rapidly restores nominal operation. In addition, the algorithm isolates a small number of key regulators and intervenes only on these, lowering both system complexity and cost. The AAC algorithm further reduces the nonlinearity effect, quickly stabilizing the frequency and power flow. This intelligent control scheme enables power grids to reliably return to stable operating conditions under a broad spectrum of fault scenarios. The proposed framework can also be used to mitigate cascading failures by adaptively controlling critical links in a variety of networked infrastructures, such as cascades of traffic congestion on road networks or fuse failures in energy-saving systems.

physics.soc-ph↗

AutoMedic: An Automated Evaluation Framework for Clinical Conversational Agents with Medical Dataset Grounding

Evaluating large language models (LLMs) has recently emerged as a critical issue for safe and trustworthy application of LLMs in the medical domain. Although a variety of static medical question-answering (QA) benchmarks have been proposed, many aspects remain underexplored, such as the effectiveness of LLMs in generating responses in dynamic, interactive clinical multi-turn conversation situations and the identification of multi-faceted evaluation strategies beyond simple accuracy. However, formally evaluating a dynamic, interactive clinical situation is hindered by its vast combinatorial space of possible patient states and interaction trajectories, making it difficult to standardize and quantitatively measure such scenarios. Here, we introduce AutoMedic, a multi-agent simulation framework that enables automated evaluation of LLMs as clinical conversational agents. AutoMedic transforms off-the-shelf static QA datasets into virtual patient profiles, enabling realistic and clinically grounded multi-turn clinical dialogues between LLM agents. The performance of various clinical conversational agents is then assessed based on our CARE metric, which provides a multi-faceted evaluation standard of clinical conversational accuracy, efficiency/strategy, empathy, and robustness. Our findings, validated by human experts, demonstrate the validity of AutoMedic as an automated evaluation framework for clinical conversational agents, offering practical guidelines for the effective development of LLMs in conversational medical applications.

cs.CL↗

Cluster-Mediated Synchronization Dynamics in Globally Coupled Oscillators with Inertia

Globally coupled oscillator systems with inertia exhibit complex synchronization patterns, among which the emergence of a couple of secondary synchronized clusters (SCs) in addition to the primary cluster (PC) is especially distinctive. Although previous studies have predominantly focused on the collective properties of the PC, the dynamics of individual clusters and their inter-cluster interactions remain largely unexplored. Here, we demonstrate that multiple clusters emerge and coexist, forming a hierarchical pattern known as the Devil's Staircase. We identify three key findings by investigating individual cluster dynamics and inter-cluster interactions. First, the PC persistently suppresses the formation of SCs during its growth and even after it has fully formed, revealing the significant impact of inter-cluster interactions on cluster formation. Second, once established, SCs induce higher-order clusters exhibiting frequency resonance via inter-cluster interactions, resulting in the Devil's Staircase pattern. Third, sufficiently large SCs can destabilize and fragment the PC, highlighting the bidirectional nature of cluster interactions. We develop a coarse-grained Kuramoto model that treats each cluster as a macroscopic oscillator to capture these inter-cluster dynamics and the resulting phenomena. Our work marks a significant step beyond system-wide averages in the study of inertial oscillator systems, offering new insights into the rich dynamics of cluster formation and synchronization in real-world applications such as power grid networks.

nlin.AO↗

Deep operator network for surrogate modeling of poroelasticity with random permeability fields

Poroelasticity -- coupled fluid flow and elastic deformation in porous media -- often involves spatially variable permeability, especially in subsurface systems. In such cases, simulations with random permeability fields are widely used for probabilistic analysis, uncertainty quantification, and inverse problems. These simulations require repeated forward solves that are often prohibitively expensive, motivating the development of efficient surrogate models. However, efficient surrogate modeling techniques for poroelasticity with random permeability fields remain scarce. In this study, we propose a surrogate modeling framework based on the deep operator network (DeepONet), a neural architecture designed to learn mappings between infinite-dimensional function spaces. The proposed surrogate model approximates the solution operator that maps random permeability fields to transient poroelastic responses. To enhance predictive accuracy and stability, we integrate three strategies: nondimensionalization of the governing equations, input dimensionality reduction via Karhunen--Loéve expansion, and a two-step training procedure that decouples the optimization of branch and trunk networks. The methodology is evaluated on two benchmark problems in poroelasticity: soil consolidation and ground subsidence induced by groundwater extraction. In both cases, the DeepONet achieves substantial speedup in inference while maintaining high predictive accuracy across a wide range of permeability statistics. These results highlight the potential of the proposed approach as a scalable and efficient surrogate modeling technique for poroelastic systems with random permeability fields.

cs.LG↗

Optimal location of reinforced inertia to stabilize power grids

The increasing adoption of renewable energy sources has significantly reduced the inertia in the modernized power grid, making the system more vulnerable. One way to stabilize the grid is to add extra inertia from unused turbines, called the fast frequency response (FFR), to the existing grid. However, reinforcing inertia can cause unintended consequences, such as more significant avalanche failures. This phenomenon is known as the Braess paradox. Here, we propose a method to find the optimal position of FFR. This method is applied to the second-order Kuramoto model to find an effective position to mitigate cascading failures. To address this, we propose a method to evaluate a ratio between the positive effects of mitigation and the negative consequences. Through this analysis, we find that the peripheral area of the network is a seemingly effective location for inertia reinforcement across various reinforcement scales. This strategy provides essential insights for enhancing the stability of power grids in a time of widespread renewable energy usage.

physics.soc-ph↗

Rethinking Test-Time Scaling for Medical AI: Model and Task-Aware Strategies for LLMs and VLMs

Test-time scaling has recently emerged as a promising approach for enhancing the reasoning capabilities of large language models or vision-language models during inference. Although a variety of test-time scaling strategies have been proposed, and interest in their application to the medical domain is growing, many critical aspects remain underexplored, including their effectiveness for vision-language models and the identification of optimal strategies for different settings. In this paper, we conduct a comprehensive investigation of test-time scaling in the medical domain. We evaluate its impact on both large language models and vision-language models, considering factors such as model size, inherent model characteristics, and task complexity. Finally, we assess the robustness of these strategies under user-driven factors, such as misleading information embedded in prompts. Our findings offer practical guidelines for the effective use of test-time scaling in medical applications and provide insights into how these strategies can be further refined to meet the reliability and interpretability demands of the medical domain.

cs.CL↗

End-to-End Breast Cancer Radiotherapy Planning via LMMs with Consistency Embedding

Recent advances in AI foundation models have significant potential for lightening the clinical workload by mimicking the comprehensive and multi-faceted approaches used by medical professionals. In the field of radiation oncology, the integration of multiple modalities holds great importance, so the opportunity of foundational model is abundant. Inspired by this, here we present RO-LMM, a multi-purpose, comprehensive large multimodal model (LMM) tailored for the field of radiation oncology. This model effectively manages a series of tasks within the clinical workflow, including clinical context summarization, radiation treatment plan suggestion, and plan-guided target volume segmentation by leveraging the capabilities of LMM. In particular, to perform consecutive clinical tasks without error accumulation, we present a novel Consistency Embedding Fine-Tuning (CEFTune) technique, which boosts LMM's robustness to noisy inputs while preserving the consistency of handling clean inputs. We further extend this concept to LMM-driven segmentation framework, leading to a novel Consistency Embedding Segmentation (CESEG) techniques. Experimental results including multi-centre validation confirm that our RO-LMM with CEFTune and CESEG results in promising performance for multiple clinical tasks with generalization capabilities.

cs.CV↗

Distribution-aware Fairness Learning in Medical Image Segmentation From A Control-Theoretic Perspective

Ensuring fairness in medical image segmentation is critical due to biases in imbalanced clinical data acquisition caused by demographic attributes (e.g., age, sex, race) and clinical factors (e.g., disease severity). To address these challenges, we introduce Distribution-aware Mixture of Experts (dMoE), inspired by optimal control theory. We provide a comprehensive analysis of its underlying mechanisms and clarify dMoE's role in adapting to heterogeneous distributions in medical image segmentation. Furthermore, we integrate dMoE into multiple network architectures, demonstrating its broad applicability across diverse medical image analysis tasks. By incorporating demographic and clinical factors, dMoE achieves state-of-the-art performance on two 2D benchmark datasets and a 3D in-house dataset. Our results highlight the effectiveness of dMoE in mitigating biases from imbalanced distributions, offering a promising approach to bridging control theory and medical image segmentation within fairness learning paradigms. The source code will be made available. The source code is available at https://github.com/tvseg/dMoE.

eess.IV↗

Susceptibility of Large Language Models to User-Driven Factors in Medical Queries

Large language models (LLMs) are increasingly used in healthcare, but their reliability is heavily influenced by user-driven factors such as question phrasing and the completeness of clinical information. In this study, we examined how misinformation framing, source authority, model persona, and omission of key clinical details affect the diagnostic accuracy and reliability of LLM outputs. We conducted two experiments: one introducing misleading external opinions with varying assertiveness (perturbation test), and another removing specific categories of patient information (ablation test). Using public datasets (MedQA and Medbullets), we evaluated proprietary models (GPT-4o, Claude 3.5 Sonnet, Claude 3.5 Haiku, Gemini 1.5 Pro, Gemini 1.5 Flash) and open-source models (LLaMA 3 8B, LLaMA 3 Med42 8B, DeepSeek R1 8B). All models were vulnerable to user-driven misinformation, with proprietary models especially affected by definitive and authoritative language. Assertive tone had the greatest negative impact on accuracy. In the ablation test, omitting physical exam findings and lab results caused the most significant performance drop. Although proprietary models had higher baseline accuracy, their performance declined sharply under misinformation. These results highlight the need for well-structured prompts and complete clinical context. Users should avoid authoritative framing of misinformation and provide full clinical details, especially for complex cases.

cs.CL↗

Read Like a Radiologist: Efficient Vision-Language Model for 3D Medical Imaging Interpretation

Recent medical vision-language models (VLMs) have shown promise in 2D medical image interpretation. However extending them to 3D medical imaging has been challenging due to computational complexities and data scarcity. Although a few recent VLMs specified for 3D medical imaging have emerged, all are limited to learning volumetric representation of a 3D medical image as a set of sub-volumetric features. Such process introduces overly correlated representations along the z-axis that neglect slice-specific clinical details, particularly for 3D medical images where adjacent slices have low redundancy. To address this limitation, we introduce MS-VLM that mimic radiologists' workflow in 3D medical image interpretation. Specifically, radiologists analyze 3D medical images by examining individual slices sequentially and synthesizing information across slices and views. Likewise, MS-VLM leverages self-supervised 2D transformer encoders to learn a volumetric representation that capture inter-slice dependencies from a sequence of slice-specific features. Unbound by sub-volumetric patchification, MS-VLM is capable of obtaining useful volumetric representations from 3D medical images with any slice length and from multiple images acquired from different planes and phases. We evaluate MS-VLM on publicly available chest CT dataset CT-RATE and in-house rectal MRI dataset. In both scenarios, MS-VLM surpasses existing methods in radiology report generation, producing more coherent and clinically relevant reports. These findings highlight the potential of MS-VLM to advance 3D medical image interpretation and improve the robustness of medical VLMs.

eess.IV↗

Improving Mortality Prediction After Radiotherapy with Large Language Model Structuring of Large-Scale Unstructured Electronic Health Records

Accurate survival prediction in radiotherapy (RT) is critical for optimizing treatment decisions. This study developed and validated the RT-Surv framework, which integrates general-domain, open-source large language models (LLMs) to structure unstructured electronic health records alongside structured clinical data. Using data from 34,276 patients and an external cohort of 852, the framework successfully transformed unstructured clinical information into structured formats. Incorporating LLM-structured clinical features improved the concordance index from 0.779 to 0.842 during external validation, demonstrating a significant performance enhancement. Key LLM-structured features, such as disease extent, general condition, and RT purpose, showed high predictive importance and aligned closely with statistically significant predictors identified through conventional statistical analyses, thereby improving model interpretability. Furthermore, the framework enhanced risk stratification, enabling more distinct differentiation among low-, intermediate-, and high-risk groups (p < 0.001) using LLM-structured clinical features. These findings highlight the potential of LLMs to convert unstructured data into actionable insights, improving predictive modeling and patient outcomes in clinics.

cs.CL↗