Shiyu Liu — Page 4 | Search arXiv

arXiv2019

Long-range Prediction of Vital Signs Using Generative Boosting via LSTM Networks

Vital signs including heart rate, respiratory rate, body temperature and blood pressure, are critical in the clinical decision making process. Effective early prediction of vital signs help to alert medical practitioner ahead of time and may prevent adverse health outcomes. In this paper, we suggest a new approach called generative boosting, in order to effectively perform early prediction of vital signs. Generative boosting consists of a generative model, to generate synthetic data for next few time steps, and several predictive models, to directly make long-range predictions based on observed and generated data. We explore generative boosting via long short-term memory (LSTM) for both the predictive and generative models, leading to a scheme called generative LSTM (GLSTM). Our experiments indicate that GLSTM outperforms a diverse range of strong benchmark models, with and without generative boosting. Finally, we use a mutual information based clustering algorithm to select a more representative dataset to train the generative model of GLSTM. This significantly improves the long-range predictive performance of high variation vital signs such as heart rate and systolic blood pressure.

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arXiv2018

Feature Selection Based on Unique Relevant Information for Health Data

Feature selection, which searches for the most representative features in observed data, is critical for health data analysis. Unlike feature extraction, such as PCA and autoencoder based methods, feature selection preserves interpretability, meaning that the selected features provide direct information about certain health conditions (i.e., the label). Thus, feature selection allows domain experts, such as clinicians, to understand the predictions made by machine learning based systems, as well as improve their own diagnostic skills. Mutual information is often used as a basis for feature selection since it measures dependencies between features and labels. In this paper, we introduce a novel mutual information based feature selection (MIBFS) method called SURI, which boosts features with high unique relevant information. We compare SURI to existing MIBFS methods using 3 different classifiers on 6 publicly available healthcare data sets. The results indicate that, in addition to preserving interpretability, SURI selects more relevant feature subsets which lead to higher classification performance. More importantly, we explore the dynamics of mutual information on a public low-dimensional health data set via exhaustive search. The results suggest the important role of unique relevant information in feature selection and verify the principles behind SURI.

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