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Taylor W. Killian

Publications and source records attributed to Taylor W. Killian.

21 records · Page 2Linked to original sources

Medical Dead-ends and Learning to Identify High-risk States and Treatments

Machine learning has successfully framed many sequential decision making problems as either supervised prediction, or optimal decision-making policy identification via reinforcement learning. In data-constrained offline settings, both approaches may fail as they assume fully optimal behavior or rely on exploring alternatives that may not exist. We introduce an inherently different approach that identifies possible "dead-ends" of a state space. We focus on the condition of patients in the intensive care unit, where a "medical dead-end" indicates that a patient will expire, regardless of all potential future treatment sequences. We postulate "treatment security" as avoiding treatments with probability proportional to their chance of leading to dead-ends, present a formal proof, and frame discovery as an RL problem. We then train three independent deep neural models for automated state construction, dead-end discovery and confirmation. Our empirical results discover that dead-ends exist in real clinical data among septic patients, and further reveal gaps between secure treatments and those that were administered.

cs.LG↗

An Empirical Study of Representation Learning for Reinforcement Learning in Healthcare

Reinforcement Learning (RL) has recently been applied to sequential estimation and prediction problems identifying and developing hypothetical treatment strategies for septic patients, with a particular focus on offline learning with observational data. In practice, successful RL relies on informative latent states derived from sequential observations to develop optimal treatment strategies. To date, how best to construct such states in a healthcare setting is an open question. In this paper, we perform an empirical study of several information encoding architectures using data from septic patients in the MIMIC-III dataset to form representations of a patient state. We evaluate the impact of representation dimension, correlations with established acuity scores, and the treatment policies derived from them. We find that sequentially formed state representations facilitate effective policy learning in batch settings, validating a more thoughtful approach to representation learning that remains faithful to the sequential and partial nature of healthcare data.

cs.LG↗

Learning Robust Representations for Automatic Target Recognition

Radio frequency (RF) sensors are used alongside other sensing modalities to provide rich representations of the world. Given the high variability of complex-valued target responses, RF systems are susceptible to attacks masking true target characteristics from accurate identification. In this work, we evaluate different techniques for building robust classification architectures exploiting learned physical structure in received synthetic aperture radar signals of simulated 3D targets.

cs.LG↗