arXiv subjects

Tianlong Chen

Publications and source records attributed to Tianlong Chen.

At least 199 records · Page 11Linked to original sources

arXiv2025

Accessing the topological properties of human brain functional sub-circuits in Echo State Networks

Recent years have witnessed an emerging trend in neuromorphic computing that centers around the use of brain connectomics as a blueprint for artificial neural networks. Connectomics-based neuromorphic computing has primarily focused on embedding human brain large-scale structural connectomes (SCs), as estimated from diffusion Magnetic Resonance Imaging (dMRI) modality, to echo-state networks (ESNs). A critical step in ESN embedding requires pre-determined read-in and read-out layers constructed by the induced subgraphs of the embedded reservoir. As \textit{a priori} set of functional sub-circuits are derived from functional MRI (fMRI) modality, it is unknown, till this point, whether the embedding of fMRI-induced sub-circuits/networks onto SCs is well justified from the neuro-physiological perspective and ESN performance across a variety of tasks. This paper proposes a pipeline to implement and evaluate ESNs with various embedded topologies and processing/memorization tasks. To this end, we showed that different performance optimums highly depend on the neuro-physiological characteristics of these pre-determined fMRI-induced sub-circuits. In general, fMRI-induced sub-circuit-embedded ESN outperforms simple bipartite and various null models with feed-forward properties commonly seen in MLP for different tasks and reservoir criticality conditions. We provided a thorough analysis of the topological properties of pre-determined fMRI-induced sub-circuits and highlighted their graph-theoretical properties that play significant roles in determining ESN performance.

q-bio.NC↗

arXiv2024

Aurora-M: Open Source Continual Pre-training for Multilingual Language and Code

Pretrained language models are an integral part of AI applications, but their high computational cost for training limits accessibility. Initiatives such as Bloom and StarCoder aim to democratize access to pretrained models for collaborative community development. Despite these efforts, such models encounter challenges such as limited multilingual capabilities, risks of catastrophic forgetting during continual pretraining, and the high costs of training models from scratch, alongside the need to align with AI safety standards and regulatory frameworks. This paper presents Aurora-M, a 15B parameter multilingual open-source model trained on English, Finnish, Hindi, Japanese, Vietnamese, and code. Continually pretrained from StarCoderPlus on 435B additional tokens, Aurora-M surpasses 2T tokens in total training token count. It is the first open-source multilingual model fine-tuned on human-reviewed safety instructions, thus aligning its development not only with conventional red-teaming considerations, but also with the specific concerns articulated in the Biden-Harris Executive Order on the Safe, Secure, and Trustworthy Development and Use of Artificial Intelligence. We evaluate Aurora-M across a wide range of tasks and languages, showcasing its robustness against catastrophic forgetting and its superior performance in multilingual settings, particularly in safety evaluations. We open-source Aurora-M and its variants to encourage responsible open-source development of large language models at https://huggingface.co/aurora-m.

cs.CL↗

arXiv2024

Political-LLM: Large Language Models in Political Science

In recent years, large language models (LLMs) have been widely adopted in political science tasks such as election prediction, sentiment analysis, policy impact assessment, and misinformation detection. Meanwhile, the need to systematically understand how LLMs can further revolutionize the field also becomes urgent. In this work, we--a multidisciplinary team of researchers spanning computer science and political science--present the first principled framework termed Political-LLM to advance the comprehensive understanding of integrating LLMs into computational political science. Specifically, we first introduce a fundamental taxonomy classifying the existing explorations into two perspectives: political science and computational methodologies. In particular, from the political science perspective, we highlight the role of LLMs in automating predictive and generative tasks, simulating behavior dynamics, and improving causal inference through tools like counterfactual generation; from a computational perspective, we introduce advancements in data preparation, fine-tuning, and evaluation methods for LLMs that are tailored to political contexts. We identify key challenges and future directions, emphasizing the development of domain-specific datasets, addressing issues of bias and fairness, incorporating human expertise, and redefining evaluation criteria to align with the unique requirements of computational political science. Political-LLM seeks to serve as a guidebook for researchers to foster an informed, ethical, and impactful use of Artificial Intelligence in political science. Our online resource is available at: http://political-llm.org/.

cs.CL↗

arXiv2024

Model-GLUE: Democratized LLM Scaling for A Large Model Zoo in the Wild

As Large Language Models (LLMs) excel across tasks and specialized domains, scaling LLMs based on existing models has garnered significant attention, which faces the challenge of decreasing performance when combining disparate models. Various techniques have been proposed for the aggregation of pre-trained LLMs, including model merging, Mixture-of-Experts, and stacking. Despite their merits, a comprehensive comparison and synergistic application of them to a diverse model zoo is yet to be adequately addressed. In light of this research gap, this paper introduces Model-GLUE, a holistic LLM scaling guideline. First, our work starts with a benchmarking of existing LLM scaling techniques, especially selective merging, and variants of mixture. Utilizing the insights from the benchmark results, we formulate an optimal strategy for the selection and aggregation of a heterogeneous model zoo characterizing different architectures and initialization.Our methodology involves the clustering of mergeable models and optimal merging strategy selection, and the integration of clusters through a model mixture. Finally, evidenced by our experiments on a diverse Llama-2-based model zoo, Model-GLUE shows an average performance enhancement of 5.61%, achieved without additional training. Codes are available at: https://github.com/Model-GLUE/Model-GLUE.

cs.LG↗

arXiv2024

Integrating Social Determinants of Health into Knowledge Graphs: Evaluating Prediction Bias and Fairness in Healthcare

Social determinants of health (SDoH) play a crucial role in patient health outcomes, yet their integration into biomedical knowledge graphs remains underexplored. This study addresses this gap by constructing an SDoH-enriched knowledge graph using the MIMIC-III dataset and PrimeKG. We introduce a novel fairness formulation for graph embeddings, focusing on invariance with respect to sensitive SDoH information. Via employing a heterogeneous-GCN model for drug-disease link prediction, we detect biases related to various SDoH factors. To mitigate these biases, we propose a post-processing method that strategically reweights edges connected to SDoHs, balancing their influence on graph representations. This approach represents one of the first comprehensive investigations into fairness issues within biomedical knowledge graphs incorporating SDoH. Our work not only highlights the importance of considering SDoH in medical informatics but also provides a concrete method for reducing SDoH-related biases in link prediction tasks, paving the way for more equitable healthcare recommendations. Our code is available at \url{https://github.com/hwq0726/SDoH-KG}.

cs.AI↗

arXiv2024

Path-RAG: Knowledge-Guided Key Region Retrieval for Open-ended Pathology Visual Question Answering

Accurate diagnosis and prognosis assisted by pathology images are essential for cancer treatment selection and planning. Despite the recent trend of adopting deep-learning approaches for analyzing complex pathology images, they fall short as they often overlook the domain-expert understanding of tissue structure and cell composition. In this work, we focus on a challenging Open-ended Pathology VQA (PathVQA-Open) task and propose a novel framework named Path-RAG, which leverages HistoCartography to retrieve relevant domain knowledge from pathology images and significantly improves performance on PathVQA-Open. Admitting the complexity of pathology image analysis, Path-RAG adopts a human-centered AI approach by retrieving domain knowledge using HistoCartography to select the relevant patches from pathology images. Our experiments suggest that domain guidance can significantly boost the accuracy of LLaVA-Med from 38% to 47%, with a notable gain of 28% for H&E-stained pathology images in the PathVQA-Open dataset. For longer-form question and answer pairs, our model consistently achieves significant improvements of 32.5% in ARCH-Open PubMed and 30.6% in ARCH-Open Books on H\&E images. Our code and dataset is available here (https://github.com/embedded-robotics/path-rag).

cs.CV↗

arXiv2024

Word-Sequence Entropy: Towards Uncertainty Estimation in Free-Form Medical Question Answering Applications and Beyond

Uncertainty estimation is crucial for the reliability of safety-critical human and artificial intelligence (AI) interaction systems, particularly in the domain of healthcare engineering. However, a robust and general uncertainty measure for free-form answers has not been well-established in open-ended medical question-answering (QA) tasks, where generative inequality introduces a large number of irrelevant words and sequences within the generated set for uncertainty quantification (UQ), which can lead to biases. This paper introduces Word-Sequence Entropy (WSE), a method that calibrates uncertainty at both the word and sequence levels, considering semantic relevance. WSE quantifies uncertainty in a way that is more closely aligned with the reliability of LLMs during uncertainty quantification (UQ). We compare WSE with six baseline methods on five free-form medical QA datasets, utilizing seven popular large language models (LLMs). Experimental results demonstrate that WSE exhibits superior performance in UQ under two standard criteria for correctness evaluation. Additionally, in terms of real-world medical QA applications, the performance of LLMs is significantly enhanced (e.g., a 6.36% improvement in model accuracy on the COVID-QA dataset) by employing responses with lower uncertainty that are identified by WSE as final answers, without any additional task-specific fine-tuning or architectural modifications.

cs.CL↗

arXiv2024

Flex-MoE: Modeling Arbitrary Modality Combination via the Flexible Mixture-of-Experts

Multimodal learning has gained increasing importance across various fields, offering the ability to integrate data from diverse sources such as images, text, and personalized records, which are frequently observed in medical domains. However, in scenarios where some modalities are missing, many existing frameworks struggle to accommodate arbitrary modality combinations, often relying heavily on a single modality or complete data. This oversight of potential modality combinations limits their applicability in real-world situations. To address this challenge, we propose Flex-MoE (Flexible Mixture-of-Experts), a new framework designed to flexibly incorporate arbitrary modality combinations while maintaining robustness to missing data. The core idea of Flex-MoE is to first address missing modalities using a new missing modality bank that integrates observed modality combinations with the corresponding missing ones. This is followed by a uniquely designed Sparse MoE framework. Specifically, Flex-MoE first trains experts using samples with all modalities to inject generalized knowledge through the generalized router ($\mathcal{G}$-Router). The $\mathcal{S}$-Router then specializes in handling fewer modality combinations by assigning the top-1 gate to the expert corresponding to the observed modality combination. We evaluate Flex-MoE on the ADNI dataset, which encompasses four modalities in the Alzheimer's Disease domain, as well as on the MIMIC-IV dataset. The results demonstrate the effectiveness of Flex-MoE highlighting its ability to model arbitrary modality combinations in diverse missing modality scenarios. Code is available at https://github.com/UNITES-Lab/flex-moe.

cs.LG↗

arXiv2024

FairSkin: Fair Diffusion for Skin Disease Image Generation

Image generation is a prevailing technique for clinical data augmentation for advancing diagnostic accuracy and reducing healthcare disparities. Diffusion Model (DM) has become a leading method in generating synthetic medical images, but it suffers from a critical twofold bias: (1) The quality of images generated for Caucasian individuals is significantly higher, as measured by the Frechet Inception Distance (FID). (2) The ability of the downstream-task learner to learn critical features from disease images varies across different skin tones. These biases pose significant risks, particularly in skin disease detection, where underrepresentation of certain skin tones can lead to misdiagnosis or neglect of specific conditions. To address these challenges, we propose FairSkin, a novel DM framework that mitigates these biases through a three-level resampling mechanism, ensuring fairer representation across racial and disease categories. Our approach significantly improves the diversity and quality of generated images, contributing to more equitable skin disease detection in clinical settings.

cs.CV↗

arXiv2024

Harnessing Your DRAM and SSD for Sustainable and Accessible LLM Inference with Mixed-Precision and Multi-level Caching

Although Large Language Models (LLMs) have demonstrated remarkable capabilities, their massive parameter counts and associated extensive computing make LLMs' deployment the main part of carbon emission from nowadays AI applications. Compared to modern GPUs like H$100$, it would be significantly carbon-sustainable if we could leverage old-fashioned GPUs such as M$40$ (as shown in Figure 1, M$40$ only has one third carbon emission of H$100$'s) for LLM servings. However, the limited High Bandwidth Memory (HBM) available on such GPU often cannot support the loading of LLMs due to the gigantic model size and intermediate activation data, making their serving challenging. For instance, a LLaMA2 model with $70$B parameters typically requires $128$GB for inference, which substantially surpasses $24$GB HBM in a $3090$ GPU and remains infeasible even considering the additional $64$GB DRAM. To address this challenge, this paper proposes a mixed-precision with a model modularization algorithm to enable LLM inference on outdated hardware with resource constraints. (The precision denotes the numerical precision like FP16, INT8, INT4) and multi-level caching (M2Cache).) Specifically, our M2Cache first modulizes neurons in LLM and creates their importance ranking. Then, it adopts a dynamic sparse mixed-precision quantization mechanism in weight space to reduce computational demands and communication overhead at each decoding step. It collectively lowers the operational carbon emissions associated with LLM inference. Moreover, M2Cache introduces a three-level cache management system with HBM, DRAM, and SSDs that complements the dynamic sparse mixed-precision inference. To enhance communication efficiency, M2Cache maintains a neuron-level mixed-precision LRU cache in HBM, a larger layer-aware cache in DRAM, and a full model in SSD.

cs.LG↗

arXiv2024

DALK: Dynamic Co-Augmentation of LLMs and KG to answer Alzheimer's Disease Questions with Scientific Literature

Recent advancements in large language models (LLMs) have achieved promising performances across various applications. Nonetheless, the ongoing challenge of integrating long-tail knowledge continues to impede the seamless adoption of LLMs in specialized domains. In this work, we introduce DALK, a.k.a. Dynamic Co-Augmentation of LLMs and KG, to address this limitation and demonstrate its ability on studying Alzheimer's Disease (AD), a specialized sub-field in biomedicine and a global health priority. With a synergized framework of LLM and KG mutually enhancing each other, we first leverage LLM to construct an evolving AD-specific knowledge graph (KG) sourced from AD-related scientific literature, and then we utilize a coarse-to-fine sampling method with a novel self-aware knowledge retrieval approach to select appropriate knowledge from the KG to augment LLM inference capabilities. The experimental results, conducted on our constructed AD question answering (ADQA) benchmark, underscore the efficacy of DALK. Additionally, we perform a series of detailed analyses that can offer valuable insights and guidelines for the emerging topic of mutually enhancing KG and LLM. We will release the code and data at https://github.com/David-Li0406/DALK.

cs.CL↗

arXiv2024

GDeR: Safeguarding Efficiency, Balancing, and Robustness via Prototypical Graph Pruning

Training high-quality deep models necessitates vast amounts of data, resulting in overwhelming computational and memory demands. Recently, data pruning, distillation, and coreset selection have been developed to streamline data volume by retaining, synthesizing, or selecting a small yet informative subset from the full set. Among these methods, data pruning incurs the least additional training cost and offers the most practical acceleration benefits. However, it is the most vulnerable, often suffering significant performance degradation with imbalanced or biased data schema, thus raising concerns about its accuracy and reliability in on-device deployment. Therefore, there is a looming need for a new data pruning paradigm that maintains the efficiency of previous practices while ensuring balance and robustness. Unlike the fields of computer vision and natural language processing, where mature solutions have been developed to address these issues, graph neural networks (GNNs) continue to struggle with increasingly large-scale, imbalanced, and noisy datasets, lacking a unified dataset pruning solution. To achieve this, we introduce a novel dynamic soft-pruning method, GDeR, designed to update the training ``basket'' during the process using trainable prototypes. GDeR first constructs a well-modeled graph embedding hypersphere and then samples \textit{representative, balanced, and unbiased subsets} from this embedding space, which achieves the goal we called Graph Training Debugging. Extensive experiments on five datasets across three GNN backbones, demonstrate that GDeR (I) achieves or surpasses the performance of the full dataset with 30%~50% fewer training samples, (II) attains up to a 2.81x lossless training speedup, and (III) outperforms state-of-the-art pruning methods in imbalanced training and noisy training scenarios by 0.3%~4.3% and 3.6%~7.8%, respectively.

cs.LG↗

arXiv2024

Is C4 Dataset Optimal for Pruning? An Investigation of Calibration Data for LLM Pruning

Network pruning has emerged as a potential solution to make LLMs cheaper to deploy. However, existing LLM pruning approaches universally rely on the C4 dataset as the calibration data for calculating pruning scores, leaving its optimality unexplored. In this study, we evaluate the choice of calibration data on LLM pruning, across a wide range of datasets that are most commonly used in LLM training and evaluation, including four pertaining datasets as well as three categories of downstream tasks encompassing nine datasets. Each downstream dataset is prompted with In-Context Learning (ICL) and Chain-of-Thought (CoT), respectively. Besides the already intriguing observation that the choice of calibration data significantly impacts the performance of pruned LLMs, our results also uncover several subtle and often unexpected findings, summarized as follows: (1) C4 is not the optimal choice for LLM pruning, even among commonly used pre-training datasets; (2) arithmetic datasets, when used as calibration data, performs on par or even better than pre-training datasets; (3) pruning with downstream datasets does not necessarily help the corresponding downstream task, compared to pre-training data; (4) ICL is widely beneficial to all data categories, whereas CoT is only useful on certain tasks. Our findings shed light on the importance of carefully selecting calibration data for LLM pruning and pave the way for more efficient deployment of these powerful models in real-world applications. We release our code at: https://github.com/abx393/llm-pruning-calibration-data.

cs.CL↗

arXiv2024

Graph Sparsification via Mixture of Graphs

Graph Neural Networks (GNNs) have demonstrated superior performance across various graph learning tasks but face significant computational challenges when applied to large-scale graphs. One effective approach to mitigate these challenges is graph sparsification, which involves removing non-essential edges to reduce computational overhead. However, previous graph sparsification methods often rely on a single global sparsity setting and uniform pruning criteria, failing to provide customized sparsification schemes for each node's complex local context. In this paper, we introduce Mixture-of-Graphs (MoG), leveraging the concept of Mixture-of-Experts (MoE), to dynamically select tailored pruning solutions for each node. Specifically, MoG incorporates multiple sparsifier experts, each characterized by unique sparsity levels and pruning criteria, and selects the appropriate experts for each node. Subsequently, MoG performs a mixture of the sparse graphs produced by different experts on the Grassmann manifold to derive an optimal sparse graph. One notable property of MoG is its entirely local nature, as it depends on the specific circumstances of each individual node. Extensive experiments on four large-scale OGB datasets and two superpixel datasets, equipped with five GNN backbones, demonstrate that MoG (I) identifies subgraphs at higher sparsity levels ($8.67\%\sim 50.85\%$), with performance equal to or better than the dense graph, (II) achieves $1.47-2.62\times$ speedup in GNN inference with negligible performance drop, and (III) boosts ``top-student'' GNN performance ($1.02\%\uparrow$ on RevGNN+\textsc{ogbn-proteins} and $1.74\%\uparrow$ on DeeperGCN+\textsc{ogbg-ppa}).

cs.LG↗

arXiv2024

Cut the Crap: An Economical Communication Pipeline for LLM-based Multi-Agent Systems

Recent advancements in large language model (LLM)-powered agents have shown that collective intelligence can significantly outperform individual capabilities, largely attributed to the meticulously designed inter-agent communication topologies. Though impressive in performance, existing multi-agent pipelines inherently introduce substantial token overhead, as well as increased economic costs, which pose challenges for their large-scale deployments. In response to this challenge, we propose an economical, simple, and robust multi-agent communication framework, termed $\texttt{AgentPrune}$, which can seamlessly integrate into mainstream multi-agent systems and prunes redundant or even malicious communication messages. Technically, $\texttt{AgentPrune}$ is the first to identify and formally define the \textit{communication redundancy} issue present in current LLM-based multi-agent pipelines, and efficiently performs one-shot pruning on the spatial-temporal message-passing graph, yielding a token-economic and high-performing communication topology. Extensive experiments across six benchmarks demonstrate that $\texttt{AgentPrune}$ \textbf{(I)} achieves comparable results as state-of-the-art topologies at merely $\$5.6$ cost compared to their $\$43.7$, \textbf{(II)} integrates seamlessly into existing multi-agent frameworks with $28.1\%\sim72.8\%\downarrow$ token reduction, and \textbf{(III)} successfully defend against two types of agent-based adversarial attacks with $3.5\%\sim10.8\%\uparrow$ performance boost.

cs.MA↗

arXiv2024

TrustLLM: Trustworthiness in Large Language Models

Large language models (LLMs), exemplified by ChatGPT, have gained considerable attention for their excellent natural language processing capabilities. Nonetheless, these LLMs present many challenges, particularly in the realm of trustworthiness. Therefore, ensuring the trustworthiness of LLMs emerges as an important topic. This paper introduces TrustLLM, a comprehensive study of trustworthiness in LLMs, including principles for different dimensions of trustworthiness, established benchmark, evaluation, and analysis of trustworthiness for mainstream LLMs, and discussion of open challenges and future directions. Specifically, we first propose a set of principles for trustworthy LLMs that span eight different dimensions. Based on these principles, we further establish a benchmark across six dimensions including truthfulness, safety, fairness, robustness, privacy, and machine ethics. We then present a study evaluating 16 mainstream LLMs in TrustLLM, consisting of over 30 datasets. Our findings firstly show that in general trustworthiness and utility (i.e., functional effectiveness) are positively related. Secondly, our observations reveal that proprietary LLMs generally outperform most open-source counterparts in terms of trustworthiness, raising concerns about the potential risks of widely accessible open-source LLMs. However, a few open-source LLMs come very close to proprietary ones. Thirdly, it is important to note that some LLMs may be overly calibrated towards exhibiting trustworthiness, to the extent that they compromise their utility by mistakenly treating benign prompts as harmful and consequently not responding. Finally, we emphasize the importance of ensuring transparency not only in the models themselves but also in the technologies that underpin trustworthiness. Knowing the specific trustworthy technologies that have been employed is crucial for analyzing their effectiveness.

cs.CL↗

arXiv2024

Enhancing Quantum Security over Federated Learning via Post-Quantum Cryptography

Federated learning (FL) has become one of the standard approaches for deploying machine learning models on edge devices, where private training data are distributed across clients, and a shared model is learned by aggregating locally computed updates from each client. While this paradigm enhances communication efficiency by only requiring updates at the end of each training epoch, the transmitted model updates remain vulnerable to malicious tampering, posing risks to the integrity of the global model. Although current digital signature algorithms can protect these communicated model updates, they fail to ensure quantum security in the era of large-scale quantum computing. Fortunately, various post-quantum cryptography algorithms have been developed to address this vulnerability, especially the three NIST-standardized algorithms - Dilithium, FALCON, and SPHINCS+. In this work, we empirically investigate the impact of these three NIST-standardized PQC algorithms for digital signatures within the FL procedure, covering a wide range of models, tasks, and FL settings. Our results indicate that Dilithium stands out as the most efficient PQC algorithm for digital signature in federated learning. Additionally, we offer an in-depth discussion of the implications of our findings and potential directions for future research.

quant-ph↗

arXiv2024

Visual Prompting Upgrades Neural Network Sparsification: A Data-Model Perspective

The rapid development of large-scale deep learning models questions the affordability of hardware platforms, which necessitates the pruning to reduce their computational and memory footprints. Sparse neural networks as the product, have demonstrated numerous favorable benefits like low complexity, undamaged generalization, etc. Most of the prominent pruning strategies are invented from a model-centric perspective, focusing on searching and preserving crucial weights by analyzing network topologies. However, the role of data and its interplay with model-centric pruning has remained relatively unexplored. In this research, we introduce a novel data-model co-design perspective: to promote superior weight sparsity by learning important model topology and adequate input data in a synergetic manner. Specifically, customized Visual Prompts are mounted to upgrade neural Network sparsification in our proposed VPNs framework. As a pioneering effort, this paper conducts systematic investigations about the impact of different visual prompts on model pruning and suggests an effective joint optimization approach. Extensive experiments with 3 network architectures and 8 datasets evidence the substantial performance improvements from VPNs over existing start-of-the-art pruning algorithms. Furthermore, we find that subnetworks discovered by VPNs from pre-trained models enjoy better transferability across diverse downstream scenarios. These insights shed light on new promising possibilities of data-model co-designs for vision model sparsification.

cs.CV↗