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Tianyi Wang

Publications and source records attributed to Tianyi Wang.

At least 73 records · Page 4Linked to original sources
arXiv2026

Heterogeneous gene network estimation for single-cell transcriptomic data via a joint regularized deep neural network

Estimation of intracellular gene networks has been a critical component of single-cell transcriptomic data analysis, which can provide crucial insights into the complex interplay between genes, facilitating the discovery of the biological basis of human life at single-cell resolution. Despite notable achievements, existing methodologies often falter in their practicality, primarily due to their narrow focus on simplistic linear relationships and inadequate handling of cellular heterogeneity. To bridge these gaps, we propose a joint regularized deep neural network method incorporating Mahalanobis distance-based K-means clustering (JRDNN-KM) to estimate multiple networks for various cell subgroups simultaneously, accounting for both unknown cellular heterogeneity and zero inflation, and, more importantly, complex nonlinear relationships among genes. We introduce an innovative selection layer for network construction, along with hidden layers that include both shared and subgroup-specific neurons, to capture common patterns and subgroup-specific variations across networks. Applied to real single-cell transcriptomic data from multiple tissues and species, JRDNN-KM demonstrates higher accuracy and biological interpretability in network estimation, and more accurately identifies cell subgroups compared to current state-of-the-art methods.Building on network construction, we further find hub genes with important biological implications and modules with statistical enrichment of biological processes.

stat.AP↗
arXiv2025

Hybrid digital-analog protocols for simulating quantum multi-body interactions

While quantum simulators promise to explore quantum many-body physics beyond classical computation, their capabilities are limited by the available native interactions in the hardware. On many platforms, accessible Hamiltonians are largely restricted to one- and two-body interactions, limiting access to multi-body Hamiltonians and to systems governed by simultaneous, non-commuting interaction terms that are central to condensed matter, quantum chemistry, and high-energy physics. We introduce and experimentally demonstrate a hybrid digital-analog protocol that overcomes these limitations by embedding analog evolution between shallow entangling-gate layers. This method produces effective Hamiltonians with simultaneous non-commuting three- and four-body interactions that are generated non-perturbatively and without Trotter error -- capabilities not practically attainable on near-term hardware using purely digital or purely analog schemes. We implement our scheme on a trapped-ion quantum processor and use it to realize a topological spin chain exhibiting prethermal strong zero modes persisting at high temperature, as well as models featuring three- and four-body interactions. Our hardware-agnostic and scalable method opens new routes to realizing complex many-body physics across quantum platforms.

quant-ph↗
arXiv2025

KEPT: Knowledge-Enhanced Prediction of Trajectories from Consecutive Driving Frames with Vision-Language Models

Accurate short-horizon trajectory prediction is crucial for safe and reliable autonomous driving. However, existing vision-language models (VLMs) often fail to accurately understand driving scenes and generate trustworthy trajectories. To address this challenge, this paper introduces KEPT, a knowledge-enhanced VLM framework that predicts ego trajectories directly from consecutive front-view driving frames. KEPT integrates a temporal frequency-spatial fusion (TFSF) video encoder, which is trained via self-supervised learning with hard-negative mining, with a k-means & HNSW retrieval-augmented generation (RAG) pipeline. Retrieved prior knowledge is added into chain-of-thought (CoT) prompts with explicit planning constraints, while a triple-stage fine-tuning paradigm aligns the VLM backbone to enhance spatial perception and trajectory prediction capabilities. Evaluated on nuScenes dataset, KEPT achieves the best open-loop performance compared with baseline methods. Ablation studies on fine-tuning stages, Top-K value of RAG, different retrieval strategies, vision encoders, and VLM backbones are conducted to demonstrate the effectiveness of KEPT. These results indicate that KEPT offers a promising, data-efficient way toward trustworthy trajectory prediction in autonomous driving.

cs.CV↗
arXiv2025

MIRROR: Multi-Modal Pathological Self-Supervised Representation Learning via Modality Alignment and Retention

Histopathology and transcriptomics are fundamental modalities in oncology, encapsulating the morphological and molecular aspects of the disease. Multi-modal self-supervised learning has demonstrated remarkable potential in learning pathological representations by integrating diverse data sources. Conventional multi-modal integration methods primarily emphasize modality alignment, while paying insufficient attention to retaining the modality-specific structures. However, unlike conventional scenarios where multi-modal inputs share highly overlapping features, histopathology and transcriptomics exhibit pronounced heterogeneity, offering orthogonal yet complementary insights. Histopathology provides morphological and spatial context, elucidating tissue architecture and cellular topology, whereas transcriptomics delineates molecular signatures through gene expression patterns. This inherent disparity introduces a major challenge in aligning them while maintaining modality-specific fidelity. To address these challenges, we present MIRROR, a novel multi-modal representation learning method designed to foster both modality alignment and retention. MIRROR employs dedicated encoders to extract comprehensive features for each modality, which is further complemented by a modality alignment module to achieve seamless integration between phenotype patterns and molecular profiles. Furthermore, a modality retention module safeguards unique attributes from each modality, while a style clustering module mitigates redundancy and enhances disease-relevant information by modeling and aligning consistent pathological signatures within a clustering space. Extensive evaluations on TCGA cohorts for cancer subtyping and survival analysis highlight MIRROR's superior performance, demonstrating its effectiveness in constructing comprehensive oncological feature representations and benefiting the cancer diagnosis.

cs.CV↗
arXiv2025

Robust Identity Perceptual Watermark Against Deepfake Face Swapping

Notwithstanding offering convenience and entertainment to society, Deepfake face swapping has caused critical privacy issues with the rapid development of deep generative models. Due to imperceptible artifacts in high-quality synthetic images, passive detection models against face swapping in recent years usually suffer performance damping regarding the generalizability issue in cross-domain scenarios. Therefore, several studies have been attempted to proactively protect the original images against malicious manipulations by inserting invisible signals in advance. However, existing proactive defense approaches demonstrate unsatisfactory results with respect to visual quality, detection accuracy, and source tracing ability. In this study, to fulfill the research gap, we propose a robust identity perceptual watermarking framework that concurrently performs detection and source tracing against Deepfake face swapping proactively. We innovatively assign identity semantics regarding the image contents to the watermarks and devise an unpredictable and nonreversible chaotic encryption system to ensure watermark confidentiality. The watermarks are robustly encoded and recovered by jointly training an encoder-decoder framework along with adversarial image manipulations. For a suspect image, falsification is accomplished by justifying the consistency between the content-matched identity perceptual watermark and the recovered robust watermark, without requiring the ground-truth. Moreover, source tracing can be accomplished based on the identity semantics that the recovered watermark carries. Extensive experiments demonstrate state-of-the-art detection and source tracing performance against Deepfake face swapping with promising watermark robustness for both cross-dataset and cross-manipulation settings.

cs.CV↗
arXiv2025

FractalForensics: Proactive Deepfake Detection and Localization via Fractal Watermarks

Proactive Deepfake detection via robust watermarks has seen interest ever since passive Deepfake detectors encountered challenges in identifying high-quality synthetic images. However, while demonstrating reasonable detection performance, they lack localization functionality and explainability in detection results. Additionally, the unstable robustness of watermarks can significantly affect the detection performance. In this study, we propose novel fractal watermarks for proactive Deepfake detection and localization, namely FractalForensics. Benefiting from the characteristics of fractals, we devise a parameter-driven watermark generation pipeline that derives fractal-based watermarks and performs one-way encryption of the selected parameters. Subsequently, we propose a semi-fragile watermarking framework for watermark embedding and recovery, trained to be robust against benign image processing operations and fragile when facing Deepfake manipulations in a black-box setting. Moreover, we introduce an entry-to-patch strategy that implicitly embeds the watermark matrix entries into image patches at corresponding positions, achieving localization of Deepfake manipulations. Extensive experiments demonstrate satisfactory robustness and fragility of our approach against common image processing operations and Deepfake manipulations, outperforming state-of-the-art semi-fragile watermarking algorithms and passive detectors for Deepfake detection. Furthermore, by highlighting the areas manipulated, our method provides explainability for the proactive Deepfake detection results.

cs.CV↗
arXiv2025

Domain wall induced topological Hall effect in the chiral-lattice ferromagnet Fe$_x$TaS$_2$

Magnetic topology and its associated emergent phenomena are central to realizing intriguing quantum states and spintronics functionalities. Designing spin textures to achieve strong and distinct electrical responses remains a significant challenge. Layered transition metal dichalcogenides offer a versatile platform for tailoring structural and magnetic properties, enabling access to a wide spectrum of topological magnetic states. Here, we report a domain-wall-driven, large, and tunable topological Hall effect (THE) in a non-centrosymmetric intercalated transition metal dichalcogenides series Fe$_x$TaS$_2$. By systematically varying the Fe intercalation level, we exert precise control over the magnetic ground states, allowing manipulation of the topological Hall effect. Real-space magnetic force microscopy (MFM) provides direct evidence of periodic magnetic stripe domain formation, confirming the microscopic origin of the observed topological transport phenomena. Our findings establish a promising way for tuning the topology of domains to generate substantial electromagnetic responses in layered magnetic materials.

cond-mat.mtrl-sci↗
arXiv2025

First experimental proof of PET imaging based on multi-anode MCP-PMTs with Cherenkov radiator-integrated window

Improving the coincidence time resolution (CTR) of time-of-flight positron emission tomography (TOF-PET) systems to achieve a higher signal-to-noise ratio (SNR) gain or even direct positron emission imaging (dPEI) is of paramount importance for many advanced new clinical applications of PET imaging. This places higher demands on the timing performance of all aspects of PET systems. One effective approach is to use microchannel plate photomultiplier tubes (MCP-PMTs) for prompt Cherenkov photon detection. In this study, we developed a dual-module Cherenkov PET imaging experimental platform, utilising our proprietary 8 * 8-anode Cherenkov radiator-integrated window MCP-PMTs in combination with custom-designed multi-channel electronics, and designed a specific calibration and correction method for the platform. Using this platform, a CTR of 103 ps FWHM was achieved. We overcame the limitations of single-anode detectors in previous experiments, significantly enhanced imaging efficiency and achieved module-level Cherenkov PET imaging for the first time. Imaging experiments involving radioactive sources and phantoms of various shapes and types were conducted, which preliminarily validated the feasibility and advancement of this imaging method. In addition, the effects of normalisation correction and the interaction probability between the gamma rays and the MCP on the images and experimental results were analysed and verified.

physics.ins-det↗
arXiv2025

Quantum Computing Universal Thermalization Dynamics in a (2+1)D Lattice Gauge Theory

Simulating non-equilibrium phenomena in strongly-interacting quantum many-body systems, including thermalization, is a promising application of near-term and future quantum computation. By performing experiments on a digital quantum computer consisting of fully-connected optically-controlled trapped ions, we study the role of entanglement in the thermalization dynamics of a $Z_2$ lattice gauge theory in 2+1 spacetime dimensions. Using randomized-measurement protocols, we efficiently learn a classical approximation of non-equilibrium states that yields the gap-ratio distribution and the spectral form factor of the entanglement Hamiltonian. These observables exhibit universal early-time signals for quantum chaos, a prerequisite for thermalization. Our work, therefore, establishes quantum computers as robust tools for studying universal features of thermalization in complex many-body systems, including in gauge theories.

quant-ph↗
arXiv2025

UAV-Based Intelligent Traffic Surveillance System: Real-Time Vehicle Detection, Classification, Tracking, and Behavioral Analysis

Traffic congestion and violations pose significant challenges for urban mobility and road safety. Traditional traffic monitoring systems, such as fixed cameras and sensor-based methods, are often constrained by limited coverage, low adaptability, and poor scalability. To address these challenges, this paper introduces an advanced unmanned aerial vehicle (UAV)-based traffic surveillance system capable of accurate vehicle detection, classification, tracking, and behavioral analysis in real-world, unconstrained urban environments. The system leverages multi-scale and multi-angle template matching, Kalman filtering, and homography-based calibration to process aerial video data collected from altitudes of approximately 200 meters. A case study in urban area demonstrates robust performance, achieving a detection precision of 91.8%, an F1-score of 90.5%, and tracking metrics (MOTA/MOTP) of 92.1% and 93.7%, respectively. Beyond precise detection, the system classifies five vehicle types and automatically detects critical traffic violations, including unsafe lane changes, illegal double parking, and crosswalk obstructions, through the fusion of geofencing, motion filtering, and trajectory deviation analysis. The integrated analytics module supports origin-destination tracking, vehicle count visualization, inter-class correlation analysis, and heatmap-based congestion modeling. Additionally, the system enables entry-exit trajectory profiling, vehicle density estimation across road segments, and movement direction logging, supporting comprehensive multi-scale urban mobility analytics. Experimental results confirms the system's scalability, accuracy, and practical relevance, highlighting its potential as an enforcement-aware, infrastructure-independent traffic monitoring solution for next-generation smart cities.

cs.CV↗
arXiv2025

A Multimodal Cross-View Model for Predicting Postoperative Neck Pain in Cervical Spondylosis Patients

Neck pain is the primary symptom of cervical spondylosis, yet its underlying mechanisms remain unclear, leading to uncertain treatment outcomes. To address the challenges of multimodal feature fusion caused by imaging differences and spatial mismatches, this paper proposes an Adaptive Bidirectional Pyramid Difference Convolution (ABPDC) module that facilitates multimodal integration by exploiting the advantages of difference convolution in texture extraction and grayscale invariance, and a Feature Pyramid Registration Auxiliary Network (FPRAN) to mitigate structural misalignment. Experiments on the MMCSD dataset demonstrate that the proposed model achieves superior prediction accuracy of postoperative neck pain recovery compared with existing methods, and ablation studies further confirm its effectiveness.

cs.CV↗
arXiv2025

A Spatial-Frequency Aware Multi-Scale Fusion Network for Real-Time Deepfake Detection

With the rapid advancement of real-time deepfake generation techniques, forged content is becoming increasingly realistic and widespread across applications like video conferencing and social media. Although state-of-the-art detectors achieve high accuracy on standard benchmarks, their heavy computational cost hinders real-time deployment in practical applications. To address this, we propose the Spatial-Frequency Aware Multi-Scale Fusion Network (SFMFNet), a lightweight yet effective architecture for real-time deepfake detection. We design a spatial-frequency hybrid aware module that jointly leverages spatial textures and frequency artifacts through a gated mechanism, enhancing sensitivity to subtle manipulations. A token-selective cross attention mechanism enables efficient multi-level feature interaction, while a residual-enhanced blur pooling structure helps retain key semantic cues during downsampling. Experiments on several benchmark datasets show that SFMFNet achieves a favorable balance between accuracy and efficiency, with strong generalization and practical value for real-time applications.

cs.CV↗
arXiv2025

Defending Deepfake via Texture Feature Perturbation

The rapid development of Deepfake technology poses severe challenges to social trust and information security. While most existing detection methods primarily rely on passive analyses, due to unresolvable high-quality Deepfake contents, proactive defense has recently emerged by inserting invisible signals in advance of image editing. In this paper, we introduce a proactive Deepfake detection approach based on facial texture features. Since human eyes are more sensitive to perturbations in smooth regions, we invisibly insert perturbations within texture regions that have low perceptual saliency, applying localized perturbations to key texture regions while minimizing unwanted noise in non-textured areas. Our texture-guided perturbation framework first extracts preliminary texture features via Local Binary Patterns (LBP), and then introduces a dual-model attention strategy to generate and optimize texture perturbations. Experiments on CelebA-HQ and LFW datasets demonstrate the promising performance of our method in distorting Deepfake generation and producing obvious visual defects under multiple attack models, providing an efficient and scalable solution for proactive Deepfake detection.

cs.CV↗
arXiv2025

Pinco: Position-induced Consistent Adapter for Diffusion Transformer in Foreground-conditioned Inpainting

Foreground-conditioned inpainting aims to seamlessly fill the background region of an image by utilizing the provided foreground subject and a text description. While existing T2I-based image inpainting methods can be applied to this task, they suffer from issues of subject shape expansion, distortion, or impaired ability to align with the text description, resulting in inconsistencies between the visual elements and the text description. To address these challenges, we propose Pinco, a plug-and-play foreground-conditioned inpainting adapter that generates high-quality backgrounds with good text alignment while effectively preserving the shape of the foreground subject. Firstly, we design a Self-Consistent Adapter that integrates the foreground subject features into the layout-related self-attention layer, which helps to alleviate conflicts between the text and subject features by ensuring that the model can effectively consider the foreground subject's characteristics while processing the overall image layout. Secondly, we design a Decoupled Image Feature Extraction method that employs distinct architectures to extract semantic and spatial features separately, significantly improving subject feature extraction and ensuring high-quality preservation of the subject's shape. Thirdly, to ensure precise utilization of the extracted features and to focus attention on the subject region, we introduce a Shared Positional Embedding Anchor, greatly improving the model's understanding of subject features and boosting training efficiency. Extensive experiments demonstrate that our method achieves superior performance and efficiency in foreground-conditioned inpainting.

cs.CV↗
arXiv2025

Spintronic Bayesian Hardware Driven by Stochastic Magnetic Domain Wall Dynamics

As artificial intelligence (AI) advances into diverse applications, ensuring reliability of AI models is increasingly critical. Conventional neural networks offer strong predictive capabilities but produce deterministic outputs without inherent uncertainty estimation, limiting their reliability in safety-critical domains. Probabilistic neural networks (PNNs), which introduce randomness, have emerged as a powerful approach for enabling intrinsic uncertainty quantification. However, traditional CMOS architectures are inherently designed for deterministic operation and actively suppress intrinsic randomness. This poses a fundamental challenge for implementing PNNs, as probabilistic processing introduces significant computational overhead. To address this challenge, we introduce a Magnetic Probabilistic Computing (MPC) platform-an energy-efficient, scalable hardware accelerator that leverages intrinsic magnetic stochasticity for uncertainty-aware computing. This physics-driven strategy utilizes spintronic systems based on magnetic domain walls (DWs) and their dynamics to establish a new paradigm of physical probabilistic computing for AI. The MPC platform integrates three key mechanisms: thermally induced DW stochasticity, voltage controlled magnetic anisotropy (VCMA), and tunneling magnetoresistance (TMR), enabling fully electrical and tunable probabilistic functionality at the device level. As a representative demonstration, we implement a Bayesian Neural Network (BNN) inference structure and validate its functionality on CIFAR-10 classification tasks. Compared to standard 28nm CMOS implementations, our approach achieves a seven orders of magnitude improvement in the overall figure of merit, with substantial gains in area efficiency, energy consumption, and speed. These results underscore the MPC platform's potential to enable reliable and trustworthy physical AI systems.

physics.app-ph↗
arXiv2025

HCOMC: A Hierarchical Cooperative On-Ramp Merging Control Framework in Mixed Traffic Environment on Two-Lane Highways

Highway on-ramp merging areas are common bottlenecks to traffic congestion and accidents. Currently, a cooperative control strategy based on connected and automated vehicles (CAVs) is a fundamental solution to this problem. While CAVs are not fully widespread, it is necessary to propose a hierarchical cooperative on-ramp merging control (HCOMC) framework for heterogeneous traffic flow on two-lane highways to address this gap. This paper extends longitudinal car-following models based on the intelligent driver model and lateral lane-changing models using the quintic polynomial curve to account for human-driven vehicles (HDVs) and CAVs, comprehensively considering human factors and cooperative adaptive cruise control. Besides, this paper proposes a HCOMC framework, consisting of a hierarchical cooperative planning model based on the modified virtual vehicle model, a discretionary lane-changing model based on game theory, and a multi-objective optimization model using the elitist non-dominated sorting genetic algorithm to ensure the safe, smooth, and efficient merging process. Then, the performance of our HCOMC is analyzed under different traffic densities and CAV penetration rates through simulation. The findings underscore our HCOMC's pronounced comprehensive advantages in enhancing the safety of group vehicles, stabilizing and expediting merging process, optimizing traffic efficiency, and economizing fuel consumption compared with benchmarks.

cs.RO↗
arXiv2025

TGLD: A Trust-Aware Game-Theoretic Lane-Changing Decision Framework for Automated Vehicles in Heterogeneous Traffic

Automated vehicles (AVs) face a critical need to adopt socially compatible behaviors and cooperate effectively with human-driven vehicles (HVs) in heterogeneous traffic environment. However, most existing lane-changing frameworks overlook HVs' dynamic trust levels, limiting their ability to accurately predict human driver behaviors. To address this gap, this study proposes a trust-aware game-theoretic lane-changing decision (TGLD) framework. First, we formulate a multi-vehicle coalition game, incorporating fully cooperative interactions among AVs and partially cooperative behaviors from HVs informed by real-time trust evaluations. Second, we develop an online trust evaluation method to dynamically estimate HVs' trust levels during lane-changing interactions, guiding AVs to select context-appropriate cooperative maneuvers. Lastly, social compatibility objectives are considered by minimizing disruption to surrounding vehicles and enhancing the predictability of AV behaviors, thereby ensuring human-friendly and context-adaptive lane-changing strategies. A human-in-the-loop experiment conducted in a highway on-ramp merging scenario validates our TGLD approach. Results show that AVs can effectively adjust strategies according to different HVs' trust levels and driving styles. Moreover, incorporating a trust mechanism significantly improves lane-changing efficiency, maintains safety, and contributes to transparent and adaptive AV-HV interactions.

cs.RO↗