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Vy Bui

Publications and source records attributed to Vy Bui.

3 recordsLinked to original sources

Look Before You Prompt, and After: Scaffolding Human-AI Collaboration in Software Tutorial Creation

With LLMs, creating software tutorials now involves steering the model's output and shaping it into a coherent, accurate learning resource, yet existing LLM tools offer writers little support for this work. By analyzing interviews with technical writers ($N=17$), we identify three requirements for how they assemble and structure multiple LLM responses, curate the context the model uses, and verify the generated content. We designed a tool called dBlocks with the following features: blocks to scope content, a context manager to edit context, and inline execution to verify code. Following a human-centered design method, we iteratively refined the design through a user study ($N=5$). In a within-subjects lab study ($N=16$) comparing dBlocks with participants' preferred workflows for LLM-assisted authoring, participants reported significantly higher confidence in the tutorials they produced with dBlocks. In addition, the tool reduced friction in verification, with writers verifying code as they drafted rather than deferring or skipping it, and helped them avoid searching long chat histories by scoping their work into blocks that kept each tutorial section and its LLM conversation together. More broadly, our work offers implications for tools that scaffold human-AI collaboration in SE workflows and shows how human-centered design can guide the development of LLM-integrated tools.

cs.SE

Training Neural Networks with Optimal Double-Bayesian Learning

Backpropagation with gradient descent is a common optimization strategy employed by most neural network architectures in machine learning. However, finding optimal hyperparameters to guide training has proven challenging. While it is widely acknowledged that selecting appropriate parameters is crucial for avoiding overfitting and achieving unbiased outcomes, this choice remains largely based on empirical experiments and experience. This paper presents a new probabilistic framework for the learning rate, a key parameter in stochastic gradient descent. The framework develops classic Bayesian statistics into a double-Bayesian decision mechanism involving two antagonistic Bayesian processes. A theoretically optimal learning rate can be derived from these two processes and used for stochastic gradient descent. Experiments across various classification, segmentation, and detection tasks corroborate the practical significance of the theoretically derived learning rate. The paper also discusses the ramifications of the proposed double-Bayesian framework for network training and model performance.

cs.LG

Virtual organelle self-coding for fluorescence imaging via adversarial learning

Fluorescence microscopy plays a vital role in understanding the subcellular structures of living cells. However, it requires considerable effort in sample preparation related to chemical fixation, staining, cost, and time. To reduce those factors, we present a virtual fluorescence staining method based on deep neural networks (VirFluoNet) to transform fluorescence images of molecular labels into other molecular fluorescence labels in the same field-of-view. To achieve this goal, we develop and train a conditional generative adversarial network (cGAN) to perform digital fluorescence imaging demonstrated on human osteosarcoma U2OS cell fluorescence images captured under Cell Painting staining protocol. A detailed comparative analysis is also conducted on the performance of the cGAN network between predicting fluorescence channels based on phase contrast or based on another fluorescence channel using human breast cancer MDA-MB-231 cell line as a test case. In addition, we implement a deep learning model to perform autofocusing on another human U2OS fluorescence dataset as a preprocessing step to defocus an out-focus channel in U2OS dataset. A quantitative index of image prediction error is introduced based on signal pixel-wise spatial and intensity differences with ground truth to evaluate the performance of prediction to high-complex and throughput fluorescence. This index provides a rational way to perform image segmentation on error signals and to understand the likelihood of mis-interpreting biology from the predicted image. In total, these findings contribute to the utility of deep learning image regression for fluorescence microscopy datasets of biological cells, balanced against savings of cost, time, and experimental effort. Furthermore, the approach introduced here holds promise for modeling the internal relationships between organelles and biomolecules within living cells.

eess.IV