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Xiao Zhou

Publications and source records attributed to Xiao Zhou.

At least 19 recordsLinked to original sources

Advancing Clinical Genomic Analysis with a Skill-Centred Agent

Clinical genomic analysis requires experts to integrate evolving guidelines, databases, and computational evidence. As sequencing has become increasingly accessible, this complex and labor-intensive process has become a major bottleneck to the timely use of genomic information in clinical decision-making. To fill this gap, we developed ClinGeX, a large-language-model agent that composes 105 curated executable skills through task-specific retrieval and dependency-aware orchestration. On 223 temporally held-out benchmark cases, ClinGeX achieved 71.7\% macro-averaged task-level concordance with expert reference classifications, compared with 45.7\% for the strongest comparator. In a three-condition, counterbalanced human-AI collaboration study, 45 clinical genomic professionals assessed 135 clinically derived cases under routine (no AI assistance), DeepSeek-assisted and ClinGeX-assisted conditions. ClinGeX assistance increased raw case-level concordance across criterion-level variant analysis, genomic interpretation in rare disease and molecular oncology decision-making (51.1\%, 57.8\%, 64.4\% versus 15.6\%, 31.1\%, 20.0\% in comparator conditions) and reduced reported interpretation time in all scenarios. During an exploratory one-month real-world non-interventional assessment, 11 experienced professionals submitted feedback on 96 self-selected analysis episodes and reported frequent conclusion adoption and time savings. These findings support executable domain skills as a promising approach to augment specialist genomic interpretation.

cs.AI↗

PACT: Plan-Augmented Coordination via Trace-Graphs for Dynamic Multi-Agent Combinatorial Optimization

Multi-agent approaches have been investigated recently as a means of improving the scalability of reinforcement learning for neural combinatorial optimization. Existing methods assume that all problem instance information is known upfront. However, real-world problems are often dynamic: relevant information is progressively revealed as the agents take actions (e.g., arriving at an edge in a routing problem only to discover it is untraversable). In such cases, existing methods fail to coordinate agents to explore and exploit the progressively revealed information. To address the arising coordination challenge, we introduce PACT (Plan-Augmented Coordination via Trace-graphs). PACT augments the environment graph with auxiliary nodes representing the plans of agents, which are connected to the resource nodes to indicate future dependencies. The proposed message-passing scheme over the augmented graph grounds inter-agent coordination in the environment and enables proactive, rather than reactive, conflict resolution. We show that PACT improves solution quality in dynamic problems relative to baselines and exhibits the best transfer to larger instances on which, remarkably, it outperforms centralized oracles with privileged access to instance uncertainty.

cs.LG↗

SpecMRL: Redesign Matryoshka Representation Learning within Parametric Spectrum

Matryoshka Representation Learning (MRL) is designed to support flexible representation sizes by jointly optimizing nested prefixes. While effective, this design lacks an explicit constraint to ensure that the leading portion provides a suitable compact encoding. To address this, we propose SpecMRL, which reorganizes the feature space to enable more effective prefix readout. Specifically, we extend MRL with a parameter-derived spectral basis organized with feature importance. SpecMRL otherwise follows standard MRL, with prefix readout performed in the learned spectral space. Experiments on MTEB show that SpecMRL outperforms MRL at all evaluated reduced dimensions, with larger gains under more aggressive compression. These results suggest that the learned spectral basis better prioritizes informative directions, enabling more effective representation compression. Notably, SpecMRL extends the performance frontier of MRL, surpassing full-dimensional MRL with only half the embedding dimensions.

cs.CL↗

WorkBorne: Discovering Agentic Tasks from Real-World Artifact Transitions

Developing terminal-based agents for long-horizon execution demands synthetic tasks that tightly couple complex instructions with authentic, interactive environments. However, current automated synthesis suffers from a fundamental asymmetry: instruction-oriented methods fabricate low-fidelity, synthetic environments, whereas resource-oriented methods treat real artifacts merely as static inputs, degrading task instructions into shallow, trivial operations. To address this limitation, we introduce WorkBorne, a synthesis framework that uses artifact transitions as the central primitive for modeling the full life-cycle of agentic tasks. In WorkBorne, each transition specifies who performs the task, which artifacts anchor the initial state and intended outcome, and the corresponding relationship between them. Specifically, WorkBorne first constructs coherent and diverse artifact corpora from iterative web retrieval, then discovers non-trivial transitions by identifying meaningful input-output artifact assemblies and the relations that connect them. Each discovered transition is finally instantiated into grounded agentic tasks. We construct 1,061 artifact corpora and 7,882 task environments, yielding 15,485 high-quality trajectories, with 53.6% exceeding 30 assistant turns. Experiments on Qwen3.5-27B and Qwen3.5-35B-A3B show that WorkBorne substantially improves over base models (i.e., improving Terminal-Bench 2.1 from 43.1% to 61.8% and ClawEval General score from 75.0 to 80.2) and achieves the strongest overall performance among other synthesis baselines (e.g., TMax (Ivison et al., 2026), RST (Li et al., 2026a), Terminal-Universe (Wu et al., 2026a)). Further analysis shows that transition is strongly associated with execution depth, while corpus breadth and transition depth provide complementary scaling gains.

cs.AI↗

SkillForgeBench: Evaluating Agent Reliability Grounded in Agent Skill Specifications

Evaluating an agent's ability to strictly satisfy diverse and procedurally complex requirements is essential to determining its practical reliability. Conducting such an evaluation demands agentic tasks that reconcile broad domain coverage with deep procedural complexity. Existing paradigms face a fundamental trade-off: expert-curated benchmarks achieve procedural depth but suffer from domain diversity bottlenecks, whereas crowdsourced benchmarks span diverse scenarios but lack execution rigor. To resolve this tension, we present SkillForgeBench, which leverages agent skills as unifying execution blueprints across three co-designed stages: (1) Resource Preparation uses domain-balanced skills to guide artifact retrieval, establishing broad workflow coverage; (2) Skill-driven Task Synthesis employs skills as procedural anchors to partition artifact roles, synthesize naturalistic task instructions, and package sandboxed scenarios for deep procedural execution; and (3) Holistic Evaluation Design translates skill-embedded requirements into fine-grained completion and process rubrics to enable strict requirement-level scoring. Comprising 842 sandboxed tasks across five major professional domains, SkillForgeBench reveals a steep capability hierarchy among eight mainstream agents, led by Opus 4.8 ($40.9\%$ strict completion). Requiring all constrains satisfaction uncovers severe capability bottlenecks across all model tiers that remain masked under individual rubric pass rates ($70.0\%$ to $85.7\%$ vs. $12.6\%$ to $40.9\%$). Crucially, under the external guidance from skills, top-tier agents obtain larger gains than low-tier agents (i.e., $Δ19.2\%$ for Opus 4.8 vs. $Δ5.8\%$ for Haiku 4.5). Finally, agents satisfy process rubrics far less frequently than completion rubrics (under $3\%$ for Haiku 4.5), proving that completion-only checks overestimate real-world agent reliability.

cs.AI↗

The Scientific Research Taste Benchmark (SciTaste-Bench): A Multi-Disciplinary Benchmark for Assessing Large Language Models' Judgment of Research Taste in Scientific Papers

Whether large language models can assess the innovativeness of academic publications matters for literature reviews, research funding screening, and academic recommendations. We introduce the Scientific Research Taste Benchmark (SciTaste), a gold-standard benchmark covering six disciplines: physics, mathematics, chemistry, biology, medicine, and finance. SciTaste measures research taste, that is, the ability to judge a paper's scientific value and potential, of which innovativeness is one of seven dimensions. It integrates metadata from NASA ADS, OpenAlex, and arXiv, aligns papers to field-specific classification systems, and scores each paper with the seven-dimensional Academic Taste Index. Dimension weights come from a bi-objective machine-learning approach (five regressors, including random forests) and are shared across all six disciplines. The benchmark includes 300 selected papers (50 per discipline) and a backup pool of 5,700 papers (950 per field) covering 1996-2023. SciTaste supports four evaluation modes: pure_qa, native_search, our structured tool-calling agent DiM (9 bibliometric tools in ADS/OpenAlex), and dimagent_v3_native. Outputs are evaluated by two complementary schemes: correlation with dimension-level accuracy, and WAPE relative error. Across ten state-of-the-art LLMs, tool-based structured evaluation generally outperformed toolless and raw web search modes, though gains were model-dependent. Physics is easiest; chemistry, biology, and medicine remain more challenging. SciTaste supplies the value-judgment substrate auto-research systems need to screen, rank, and prioritize candidate ideas. Dataset, harness, and scoring code are available on Hugging Face at https://huggingface.co/datasets/skylenage/SciTaste-benchmark.

cs.DL↗

From Static Personal Values to Contextualized Personalization: Bayesian Personalized Value Alignment for LLMs

Personalized value alignment has become increasingly important as large language models (LLMs) are expected to accommodate diverse user preferences. However, existing methods typically align model outputs with a static value profile across prompts, overlooking that the salience of value dimensions varies substantially across contexts. Inspired by Lewin's Field Theory, which views human behavior as jointly shaped by personal dispositions and situational constraints, we model personal values as priors and context-dependent preferences as posteriors. We propose BaCVA, an inference-time Bayesian Context-aware personalized Value Alignment method that approximates posterior personalized preferences by integrating static personal values with scenario-specific value salience. BaCVA first estimates contextual value salience from generally normative responses, and then employs a dual-view personalization module to infer posterior preferences from complementary personal-value and scenario-driven perspectives. This Bayesian formulation enables more accurate and adaptive personalized value alignment while improving data efficiency via prior values. Extensive experiments on benchmarks demonstrate its superiority over strong baselines.

cs.AI↗

BackTrend: Evaluating Scientific Weak-Signal Prediction via Backward Reconstruction

Scientific weak signals are early, low-visibility research directions that later become central to mature scientific topics, yet existing resources such as trend tracking, citation forecasting, and foresight reports rarely provide validated reference sets that link concrete early precursors to later paradigms. We introduce BackTrend, a retrospective benchmark in which, given a mature target topic and a temporal evidence constraint, systems must recover two types of precursors: problem-space signals, underrecognized research problems, and solution-space signals, emerging methods for known problems. BackTrend contains 25 mature target topics in artificial intelligence and machine learning and 66 human-validated weak signals, reconstructed from large-scale literature by grounding each candidate in its 2019-2024 publication-frequency trajectory. We evaluate frontier LLMs, RAG systems, and agentic research systems using semantic matching and coverage-based metrics. Current systems often generate plausible but misaligned precursors, exhibiting topic drift, granularity mismatch, near-miss matching, and incomplete coverage; the strongest system achieves only 10.1% F1, while Coverage10 reaches at most 18.5% of the reference signals. Our budget analyses show that additional retrieval and web-search evidence can improve performance up to a moderate budget, but does not by itself close the substantial performance gap.

cs.AI↗

On the Efficiency-Safety Dilemma in Large Reasoning Models

Large reasoning models (LRMs) incur high inference costs, often mitigated by efficiency techniques like quantization and pruning. However, the impact of these techniques on model adversarial robustness remains largely unexplored. This study provides the first comprehensive analysis of the interplay between efficiency, jailbreak vulnerability, and reasoning in LRMs. We find that while efficiency methods seemingly reduce the success rate of jailbreak attacks, this improvement is often superficial. It largely arises from degraded reasoning capabilities leading to "attempted but failed" malicious responses, rather than an increase in genuine alignment. Mechanistic analysis of representational drift confirms this, revealing a strict coupling between reasoning capability loss and the model's inability to maintain malicious semantic trajectories. Additionally, we identify quantization with pruning as the optimal strategy to balance efficiency and robustness. These findings clarify the distinction between true safety alignment and capability-induced failure, providing an empirical foundation for LRM deployment.

cs.CL↗

GrowMTP: Can RL Grow Its Own Draft Head?

Reinforcement learning (RL) post-training drives the frontier capabilities of large language models, with its wall-clock dominated by autoregressive rollout generation. Speculative decoding is an established remedy for this bottleneck, but existing draft heads must be pretrained or warmed up before RL, introducing substantial training cost outside the RL run to be accelerated. We observe that RL training itself provides both conditions required for online draft-head training: its rollout distribution is far narrower than that of pretraining, and its verification step continuously produces supervision signals aligned with this distribution. Building on these observations, we propose GrowMTP, which uses this supervision to train a draft head from scratch entirely within the RL loop, with all head updates detached from the policy backbone. On Qwen3-4B (no draft head), MiMo-7B-SFT (weak head), and Qwen3.5-4B-Base (strong head), GrowMTP achieves rollout speedups of 2.13x, 1.93x, and 1.36x, and end-to-end speedups of 1.60x, 1.41x, and 1.20x, respectively. GrowMTP therefore serves existing RL training frameworks as a modular component, particularly offering a from-scratch acceleration path for models without pretrained draft heads.

cs.LG↗

DeepShare: Assurance-Driven Deep Learning Job Scheduling for Multi-Tenant Clusters

Multi-tenant GPU clusters frequently remain underutilized even when tenants experience long queueing delays, because quota control, queue ordering, preemption, and GPU sharing are driven by different local signals. We present DeepShare, a scheduler that uses a continuous tenant-assurance signal to coordinate these decisions at runtime. DeepShare combines elastic quota borrowing, tenant-specific runtime prediction, cost-aware best-effort preemption, and interference-aware MPS colocation, while using the same assurance signal to decide when borrowed capacity should be reclaimed and when sharing should become more conservative. In trace-driven experiments on 23,859 Venus jobs and 3,200 internal jobs, DeepShare achieves an average GPU utilization of 70.58%, a 29.5% improvement over the strongest non-intrusive sharing baseline, while reducing average queueing delay by 46%. On a 16-GPU Kubernetes testbed, it reduces the average job completion time by 34% and maintains 93% QoS compliance for guaranteed tenants. These results show that treating tenant assurance as a runtime control loop achieves a more advantageous utilization-QoS trade-off than optimizing quotas, scheduling, and resource sharing independently.

cs.DC↗

AlignDPO: Preference-Gated Alignment for Reducing Hallucination in Decoder-Only TTS

Decoder-only text-to-speech (TTS) models scale efficiently but remain prone to content hallucinations that arise from weak text-speech alignment during autoregressive generation. We find that robustness is governed by a non-monotone relation to the sharpness of the alignment-bearing attention heads: a moderate degree is best, whereas over-sharpening is no better than the unaligned backbone and even less robust. Guided by this, we present AlignDPO, a post-training method that reaches this moderate regime by folding a lightweight connectionist-temporal-classification (CTC) alignment term into Direct Preference Optimization (DPO), applied only to the chosen samples, with no architectural or inference-time change. On the Seed-TTS-Eval English set, this significantly reduces the content-hallucination and word error rates relative to a strong DPO baseline and lowers the severe content-hallucination rate to ~0.6% (from 4.4%); a listening study further finds it preferred for naturalness over both the backbone and that baseline. Alignment is thus best learned and kept moderate rather than maximized or imposed at decoding. Audio samples are available at https://align-dpo-demo.vercel.app.

eess.AS↗

Classification of Solutions to a Critical Fourth-Order Equation on Complete Non-compact Manifolds

We study the critical biharmonic equation \[ Δ^2 u=u^{\frac{n+4}{n-4}}, \] on a complete, connected, and non-compact Riemannian manifold \((M^n,g)\) of dimension \(n\geq 5\) with non-negative Ricci curvature. We establish an optimal pointwise second-order derivative estimate by Bernstein's method and the continuity method. Using invariant tensors, we derive a differential inequality that yields a rigidity result. More precisely, if there exists a positive finite energy solution, then the manifold is isometric to the Euclidean space \(\mathbb{R}^n\), and the solution is given by \[ u(x)= \frac{ \left[λ^2 n(n-4)(n^2-4)\right]^{\frac{n-4}{8}} } {\left(1+λ|x-x_0|^2\right)^{\frac{n-4}{2}}}, \qquad λ>0,\quad x_0\in\mathbb{R}^n . \]

math.DG↗

Latency-Aware Orchestration for Multi-Agent LLM Workflows on Heterogeneous GPUs

Concurrent multi-agent workflows expose future dependencies and serving-state requirements while running on heterogeneous GPU pools with time-varying load, model residency, and resource availability. The logical workflow defines the required computation, whereas its physical scheduling units, model-lifecycle actions, resource ordering, and placement must be selected according to the observed pool state. We present a prediction-guided runtime that uses workflow forecasts to construct and optimize a physical execution graph. Predictor estimates device-specific activation latency, peak memory, and model-loading cost, then propagates these predictions through workflow dependencies to forecast activation readiness and future model demand. Constructor builds semantics-preserving fusion and model-lifecycle alternatives, while Scheduler jointly optimizes their selection, placement, and execution order based on the live pool state. Across a workload spanning three workflow scenarios on a heterogeneous GPU pool, our system reduces end-to-end makespan and overall p95 completion latency under burst arrivals by up to 36.8% and 25.9%, respectively, over state-of-the-art workflow schedulers. It also saves up to 24.63 GPU-s per completed session.

cs.DC↗

Learning Query-Specific Rubrics from Human Preferences for DeepResearch Report Generation

Nowadays, developing reliable DeepResearch-style long-form report generation remains challenging, as training and evaluation lack verifiable reward signals. Accordingly, rubric-based evaluation has become a common practice. However, existing approaches either rely on coarse, pre-defined rubrics that lack sufficient granularity or depend on manually constructed query-specific rubrics that are costly and difficult to scale. In this paper, we propose a pipeline to train preference-grounded query-specific rubric generators tailored for DeepResearch report generation. We first construct a dataset of DeepResearch-style queries annotated with human preferences over paired reports, and train rubric generators via reinforcement learning with a hybrid reward combining preference consistency, format validity, and LLM-based rubric evaluation. We evaluate the resulting rubric generators in two stages. First, on a held-out human-preference test set, the learned rubrics discriminate preferred from rejected reports more effectively than generic, prompted, or SFT-trained rubric alternatives. Second, when used as reward signals to train DeepResearch systems, our rubric generators yield substantial performance gains under both a simple single-agent ReAct framework and a complex multi-agent workflow on the DeepResearch Bench.

cs.CL↗

Finding Shortest Reconfiguration Sequences on Independent Set Polytopes

We initiate the study of the shortest reconfiguration problem for independent sets under the adjacency relation derived from the independent set polytope. Given a graph and two independent sets, the problem asks for a shortest sequence transforming one into the other such that the subgraph induced by the symmetric difference of any two consecutive sets is connected. This is equivalent to finding a shortest path on the $1$-skeleton of the independent set polytope. We prove that the problem is NP-hard even on planar graphs of bounded degree, as well as on split graphs. Notably, the hardness for planar graphs of bounded degree still holds even when deciding whether the target can be reached in at most two steps. For split graphs, we further show the W[2]-hardness when parameterized by the number of steps, as well as the inapproximability of the optimal length. As a consequence, we prove that the length of a shortest path between two vertices of a 0/1 polytope in $\mathbb{R}^n$ described by $O(n)$ linear inequalities is hard to approximate within a factor of $(1-\varepsilon)\ln n$ for any constant $ε>0$, unless $P=NP$. On the positive side, we provide polynomial-time algorithms for block graphs, cographs, and bipartite chain graphs. Moreover, for paths and cycles, we show that the optimal length of the shortest reconfiguration sequence exactly matches a trivial upper bound.

cs.DS↗

Controllable Affective Generation via Latent Vector Steering

Large Language Models (LLMs) often produce emotionally flattened responses after alignment, limiting their effectiveness in affect-sensitive applications. In this paper, we propose EmoVec, a lightweight framework for controllable affective generation via latent vector steering. EmoVec extracts emotion-specific directions from paired neutral and emotion-conditioned responses using contrastive activation addition, and further refines them through task-specific debiasing and principal subspace removal. During inference, these vectors are injected into the final residual stream with static or scenario-adaptive scaling, enabling continuous control over emotional intensity without updating model weights. Experiments across three LLMs and eight emotions show that EmoVec consistently improves emotional salience while largely preserving semantic content, fluency, and coherence. Ablation studies and human evaluation further confirm the effectiveness of vector purification and adaptive scaling, establishing EmoVec as a practical inference-time method for affective control in deployed LLMs.

cs.CL↗

SpotSound: Enhancing Large Audio-Language Models with Fine-Grained Temporal Grounding

Large Audio-Language Models (ALMs) have recently demonstrated remarkable capabilities in holistic audio understanding, yet they remain unreliable for temporal grounding, i.e., the task of pinpointing exactly when an event occurs within long-form audio. This limitation stems from two factors: training data dominated by clip-level supervision lacking precise timestamps, and benchmarks that fail to simulate real-world scenarios where short events are obscured by dense background sounds. In this paper, we introduce SpotSound, an audio language model designed for grounding audio events. SpotSound incorporates a novel training objective, specifically designed to suppress hallucinated timestamps for events absent from the input. Additionally, we present SpotSound-Bench, a challenging temporal grounding benchmark where target events occupy less than ~10% of each clip, creating a rigorous 'needle-in-a-haystack' evaluation. Experiments demonstrate that SpotSound achieves state-of-the-art results on temporal grounding benchmarks while maintaining robust performance across general downstream audio-language tasks. Code, models and benchmark are released on https://loiesun.github.io/spotsound/

cs.SD↗