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arXiv2026

Longitudinal Retinal Vascular Remodeling in Myopic Children Treated with Orthokeratology or Defocus Lenses: A Two-Year Comparative Study

Purposes: To characterize longitudinal retinal vascular changes in myopic children treated with orthokeratology (OK) or multifocal defocus lenses (Defocus) and to examine their association with axial elongation. Methods: In this retrospective cohort study, 43 myopic children underwent comprehensive clinical examination and fundus photography at baseline, 12 months, and 24 months. Axial length (AL) and spherical equivalent refraction (SER) were recorded at baseline, 6, 12, and 24 months. An automated segmentation model extracted vascular parameters, main vessel angle (MA), branching angle (BA), bifurcation edge angle (BEA), crossover point (COP), and terminal vessel count (TVC). Repeated-measures ANOVA assessed temporal changes. Pearson or Spearman correlations evaluated associations between AL and vascular metrics. Results: Over 24 months, the OK group exhibited significantly slower axial elongation than the Defocus group (0.214 mm and 0.522 mm, p < 0.01). In the OK group, MA and BA decreased modestly, BEA in arteries declined gradually, but COP and TVC remained relatively stable. The Defocus group demonstrated more pronounced decreases in MA and BA, an increase in BEA, and significant reductions in COP and TVC (p < 0.05). Correlation analysis revealed stronger associations between AL and vascular parameters, especially COP and TVC, in the Defocus group at all time points, whereas only BA and BEA correlated with AL in the OK group. Conclusions: OK lenses mitigate axial elongation and induce milder retinal vascular remodeling compared to Defocus lenses. Distinct temporal patterns of vascular metrics changes were observed between the two interventions, and correlate differentially with axial growth.

cs.CV↗

arXiv2026

Graph-MambaNav: Spatial-Temporal Graph Mamba Leveraging Object-Relation Knowledge for Object-Goal Navigation

Object-goal navigation requires an agent to reason over object relationships and prioritize target-relevant objects for efficient decision making in unseen environments. While existing graph-based methods incorporate target-awareness at the feature or attention level, they remain permutation-invariant and lack an explicit mechanism to control information propagation order, limiting their ability to model target-dependent importance and long-range dependencies. In contrast, Graph-Mamba highlights that node prioritization through sequence ordering is critical for effective global reasoning. In this work, we investigate the node prioritization mechanism in Graph-Mamba and study its role in object navigation. We propose Graph-MambaNav, a target-aware spatial-temporal graph encoding framework that introduces a heuristic ordering over objects based on their relevance to the target, allowing more informative objects to be processed later to aggregate richer context. Both node ordering and edge weights are initialized from LLM-derived commonsense object relationships, providing a unified prior for structured reasoning. A spatial module integrates local message passing with global GraphMamba-based selective scanning, while a temporal module applies Mamba-based sequence modeling over object-wise temporal orders, allowing selective aggregation of historical context for long-range temporal reasoning. Experiments on AI2-THOR and RoboTHOR demonstrate improved navigation performance with generalization, and additional real-world robot deployment further validates the effectiveness of our proposed approach.

cs.RO↗