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Yaping Qi

Publications and source records attributed to Yaping Qi.

5 recordsLinked to original sources

Focal-point scanning for dose delivery and optimization with focused laser-accelerated very-high-energy electron beams

Focused very-high-energy electron (VHEE) beams can produce localized dose enhancement at selected depths, but irradiation of a finite target requires coordinated control of multiple focal positions, incidence directions, and beam weights while limiting exposure of nearby organs at risk (OARs). We present Focal-Point Scanning (FPS), a dose delivery and optimization method developed for laser wakefield accelerator (LWFA)-driven VHEE beams. The method is based on a two-dipole focusing system that produces single-plane beam convergence and allows the focal position to be varied by changing the magnetic field strength. FPS distributes focal points throughout the planning target volume and determines focal-point-specific incidence sectors according to the geometry of nearby critical OARs. The method was evaluated using the AAPM TG119 C-shape benchmark and one previously treated lung radiotherapy case. At matched target coverage, FPS reduced the TG119 Core mean dose by approximately one half relative to parallel VHEE and intensity-modulated x-ray plans, approaching the single-field proton pencil-beam-scanning reference. In the lung case, FPS maintained target coverage comparable to the clinical volumetric modulated arc therapy reference while reducing the mean dose to every evaluated OAR; spinal-cord mean and maximum doses decreased by 93.2% and 87.2%, respectively. The evaluated OAR mean doses varied little across rms energy spreads of 0 to 10% and for a flat-top electron spectrum spanning 150 to 250 MeV. These results demonstrate that focal-point-specific angular selection can translate focused-beam physics into effective OAR sparing and support FPS as a planning strategy for broadband LWFA-VHEE radiotherapy.

physics.med-ph

Advancing Noise-Resilient Twist Angle Characterization in Bilayer Graphene through Raman Spectroscopy via GAN-CNN Modeling

In this study, we introduce an innovative methodology for robust twist angle identification in bilayer graphene using Raman spectroscopy, featuring the integration of generative adversarial network and convolutional neural network (GAN-CNN). Our proposed approach showcases remarkable resistance to noise interference, particularly in ultra-low Signal-to-Noise Ratio (SNR) conditions. We demonstrate the GAN-CNN model's robust learning capability, even when SNR reaches minimal levels. The model's exceptional noise resilience negates the necessity for preprocessing steps, facilitating accurate classification, and substantially reducing computational expenses. Empirical results reveal the model's prowess, achieving heightened accuracy in twist angle identification. Specifically, our GAN-CNN model achieves a test accuracy exceeding 99.9% and a recall accuracy of 99.9%, relying on an augmented dataset containing 4209 spectra. This work not only contributes to the evolution of noise-resistant spectral analysis methodologies but also provides crucial insights into the application of advanced deep learning techniques for bilayer graphene characterization through Raman spectroscopy. The findings presented herein have broader implications for enhancing the precision and efficiency of material characterization methodologies, laying the foundation for future advancements in the field.

physics.app-ph

Deep Learning Assisted Raman Spectroscopy for Rapid Identification of 2D Materials

Two-dimensional (2D) materials have attracted extensive attention due to their unique characteristics and application potentials. Raman spectroscopy, as a rapid and non-destructive probe, exhibits distinct features and holds notable advantages in the structural characterization of 2D materials. However, traditional data analysis of Raman spectra relies on manual interpretation and feature extraction, which are both time-consuming and subjective. In this work, we employ deep learning techniques, including classificatory and generative deep learning, to assist the analysis of Raman spectra of typical 2D materials. For the limited and unevenly distributed Raman spectral data, we propose a data augmentation approach based on Denoising Diffusion Probabilistic Models (DDPM) to augment the training dataset and construct a four-layer Convolutional Neural Network (CNN) for 2D material classification. Experimental results illustrate the effectiveness of DDPM in addressing data limitations and significantly improved classification model performance. The proposed DDPM-CNN method shows high reliability, with 100%classification accuracy. Our work demonstrates the practicality of deep learning-assisted Raman spectroscopy for high-precision recognition and classification of 2D materials, offering a promising avenue for rapid and automated spectral analysis.

physics.app-ph

Applications of Raman Spectroscopy in Clinical Medicine

Raman spectroscopy provides spectral information related to the specific molecular structures of substances and has been well established as a powerful tool for studying biological tissues and diagnosing diseases. This article reviews recent advances in Raman spectroscopy and its applications in diagnosing various critical diseases, including cancers, infections, and neurodegenerative diseases, and in predicting surgical outcomes. These advances are explored through discussion of state-of-the-art forms of Raman spectroscopy, such as surface-enhanced Raman spectroscopy, resonance Raman spectroscopy, and tip-enhanced Raman spectroscopy employed in biomedical sciences. We discuss biomedical applications, including various aspects and methods of ex vivo and in vivo medical diagnosis, sample collection, data processing, and achievements in realizing the correlation between Raman spectra and biochemical information in certain diseases. Finally, we present the limitations of the current study and provide perspectives for future research.

physics.app-ph

Observation of room-temperature ferroelectricity in elemental Te nanowires

Ferroelectrics are essential in low-dimensional memory devices for multi-bit storage and high-density integration. A polar structure is a necessary premise for ferroelectricity, mainly existing in compounds. However, it is usually rare in elemental materials, causing a lack of spontaneous electric polarization. Here, we report an unexpected room-temperature ferroelectricity in few-chain Te nanowires. Out-of-plane ferroelectric loops and domain reversal are observed by piezoresponse force microscopy. Through density functional theory, we attribute the ferroelectricity to the ion-displacement created by the interlayer interaction between lone pair electrons. Ferroelectric polarization can induce a strong field effect on the transport along the Te chain, supporting a self-gated field-effect transistor. It enables a nonvolatile memory with high in-plane mobility, zero supply voltage, multilevel resistive states, and a high on/off ratio. Our work provides new opportunities for elemental ferroelectrics with polar structures and paves a way towards applications such as low-power dissipation electronics and computing-in-memory devices.

cond-mat.mtrl-sci