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Yuqing Feng

Publications and source records attributed to Yuqing Feng.

6 recordsLinked to original sources

Pediatric ECG foundation model via adult-to-pediatric fine-tuning: downstream tasks and clinical evaluation

Pediatric electrocardiogram (ECG) interpretation is complicated by age-dependent electrophysiological changes that limit direct transfer of adult AI models. We asked whether an adult ECG foundation model could be adapted to pediatric ECGs. Using 339,563 12-lead ECGs from 238,189 children, we compared direct application, pediatric fine-tuning, and training from scratch under an identical architecture. Direct transfer was poor (mean AUC 0.8256). Fine-tuning reached 0.9695, above de novo training (0.9661), and attained 0.9079 using only 1% of training data. On 10,999 external ECGs, fine-tuning achieved a mean AUC of 0.9385 across 30 labels. It generalized to age regression (MAE 1.12 years) and congenital heart disease classification (AUC 0.9562). Across 17 clinicians and 100 cases, diagnostic accuracy rose from 56.8% to 65.4% (p < 0.001) and did not decline when AI erred. Adult ECG foundation models require pediatric adaptation; fine-tuning offers a data-efficient route to scalable pediatric ECG AI.

cs.AI↗

Auditing evaluation artifacts and data leakage in large language model systems for rare disease diagnosis

Augmented large language model (LLM) systems have reported high benchmark accuracies in rare disease diagnosis, yet their real-world clinical utility remains unproven. A recent meta-analysis flagged augmented LLM diagnostic evaluations as having a high risk of bias due to suspected data leakage; however, the precise impact of these vulnerabilities on model inference has yet to be fully quantified. In this study, we present a comprehensive empirical audit to quantify evaluation artifacts across prevailing AI paradigms, using a repository of over 60,000 cases from diverse public and independent clinical cohorts. By reconstructing a state-of-the-art agentic framework, we demonstrate that candidate-space contamination artificially inflates performance: enforcing strict cross-dataset isolation resulted in a marked performance decline, with the cross-dataset mean Recall@1 decreasing from 54.3% (under conventional one-vs-rest evaluation) to 40.3% (Hedges' g = 0.94). Similar spatial overfitting in supervised classifiers caused diagnostic accuracy to drop from an internal mean of 42.9% to 16.7% across external cohorts (Cohen's d = 2.01). Furthermore, we quantify how LLMs infer diagnoses by exploiting retrospective therapeutic cues in clinical narratives, and how temporal misalignment in foundational knowledge bases leads to performance fluctuations. We conclude that prevailing evaluation protocols for augmented LLM systems inadvertently reflect data leakage rather than genuine medical reasoning. To address these systematic artifacts, we propose a rigorous evaluation framework - coupling strict data-isolation protocols with standardized benchmarking safeguards - to ensure future diagnostic AI for rare diseases is evaluated on actual clinical robustness.

cs.AI↗

Unified Multiparadigm Fusion Intelligence for Rare Disease Diagnosis

Rare diseases (RDs) affect an estimated 300 million people globally, leaving patients to navigate a protracted diagnostic odyssey constrained by clinical scarcity and fragmented medical knowledge. Artificial intelligence (AI) has progressively advanced RD diagnostics, from symbolic methods and deep learning to large language model (LLM)-based systems. However, each paradigm carries structural limitations: symbolic methods are bounded by knowledge completeness, neural models sacrifice interpretability, and LLM-based systems are vulnerable to evaluation biases like data leakage. In this study, we introduce FusionRare, a unified multiparadigm fusion framework integrating knowledge-driven symbolic reasoning, deep-learning pattern recognition, case-based patient retrieval, and LLM-based heuristic inference via statistical meta-aggregation and knowledge-enhanced agentic reflection. Evaluated on 2,528 strictly isolated clinical cases, FusionRare achieves state-of-the-art RD prioritization, attaining a macro-averaged Recall @1 of 51% for phenotype-only diagnosis and 79% for phenotype-genotype joint analysis. These results represent decisive advantages over the advanced agentic system DeepRare, frontier LLMs including GPT 5.5, and specialized tools like PhenoBrain and LIRICAL under stringent anti-leakage protocols. A randomized, crossover clinician-AI validation demonstrated that FusionRare elevates the true diagnostic rank in 45% of decisions, improves physician confidence in 62%, and reduces time to diagnosis by 21%. These findings indicate that reconciling these orthogonal AI paradigms significantly enhances diagnostic capabilities, bridging the gap between computational benchmarks and actionable clinical reliability. More broadly, this work provides a replicable framework for deploying trustworthy diagnostic AI across complex, high-stakes, and underserved medical domains.

cs.AI↗

SurgNarrator: A Generative Retrieval Framework for Surgical Video Understanding

Surgical procedures unfold as structured and recurring clinical events, whose real-time understanding via intraoperative surgical videos is critical for intraoperative decision-making and support. However, existing video understanding methods force a trade-off: autoregressive video-language models support comprehensive reasoning but are not practical for time-sensitive clinical applications, whereas contrastive models offer low latency but struggle with complex scene understanding. Recently, generative retrieval has been explored for general-domain video understanding, but transferring it to surgery is not trivial because near-identical visual appearances may indicate semantically distinct events, and the terminology involved is highly surgery-specific. To this end, we propose SurgNarrator, a new generative retrieval framework tailored for surgical video understanding. We construct a well-curated surgery-centric vocabulary from surgical captions to define a clinically meaningful retrieval space. We then adapt the pre-trained Qwen3-VL-Embedding-8B to learn discriminative clinical representations with a temporally-aware contrastive objective. During inference, a hierarchical, procedure-aware retrieval strategy narrows the search space to the relevant procedure type, delivering fast and effective responses. Our method is comprehensively evaluated on twelve benchmarks in a zero-shot setting and achieves consistent performance gains over state-of-the-art baselines, while reducing output-stage latency by more than two orders of magnitude compared with the generative baseline.

cs.CV↗

Impacts of flow velocity and microbubbles on water flushing in a horizontal pipeline

Water flushing to remove particle sediment is essential for safe and continuous transport of many industrial slurries through pipelines. An efficient flushing strategy may reduce water consumption and the cost associated with water usage, and help water conservation for sustainability. In this study, a computational fluid dynamics (CFD) model coupled with the kinetic theory of granular flow for the flushing process is presented. The CFD models were validated against field data collected from a coal slurry pipeline of 128 $km$ in length, 0.575~$m$ in diameter, achieving an average error of less than 15\% for outlet solid concentration over time. A parametric study evaluated the effects of water velocity (1.88-5.88~$m/s$), bubble size (50~$μm$, 150~$μm$, and 1000~$μm$) and bubble volume fraction (0.05-0.2) on flushing performance including pipeline cleanness, cleanness efficiency, and water consumption. The obtained outcomes indicate that higher water velocity is preferred and an increase in water velocity from $1.88~m/s$ to $5.88~m/s$ reduces the water consumption by $28\%$. Large bubbles may hinder the flushing process and increase the water consumption by $23\%$. Remarkably, small bubbles facilitates the flushing process and lead to $35\%$ reduction in water consumption. These effects are attributed to the turbulent characteristics in the pipelines in presence of microbubbles.

physics.flu-dyn↗

City-Level Foreign Direct Investment Prediction with Tabular Learning on Judicial Data

To advance the United Nations Sustainable Development Goal on promoting sustained, inclusive, and sustainable economic growth, foreign direct investment (FDI) plays a crucial role in catalyzing economic expansion and fostering innovation. Precise city-level FDI prediction is quite important for local government and is commonly studied based on economic data (e.g., GDP). However, such economic data could be prone to manipulation, making predictions less reliable. To address this issue, we try to leverage large-scale judicial data which reflects judicial performance influencing local investment security and returns, for city-level FDI prediction. Based on this, we first build an index system for the evaluation of judicial performance over twelve million publicly available adjudication documents according to which a tabular dataset is reformulated. We then propose a new Tabular Learning method on Judicial Data (TLJD) for city-level FDI prediction. TLJD integrates row data and column data in our built tabular dataset for judicial performance indicator encoding, and utilizes a mixture of experts model to adjust the weights of different indicators considering regional variations. To validate the effectiveness of TLJD, we design cross-city and cross-time tasks for city-level FDI predictions. Extensive experiments on both tasks demonstrate the superiority of TLJD (reach to at least 0.92 R2) over the other ten state-of-the-art baselines in different evaluation metrics.

cs.AI↗