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Zhen Yu

Publications and source records attributed to Zhen Yu.

At least 19 recordsLinked to original sources

ByteAction: Byte-space Action Recognition Foundation Model

Byte-space Action Recognition (BAR) aims to recognize human actions directly from compressed image bitstreams without any pixel decoding. By operating entirely in byte space, BAR is inherently independent of file integrity and pixel-level reconstruction, making it naturally applicable to privacy-sensitive scenarios and robust against bitstream corruption. In this paper, we propose ByteAction, a BAR foundation model that achieves accurate action recognition on corrupted image bitstreams. ByteAction follows a dual-view byte-level recognition framework. It constructs weakly and strongly corrupted bitstream views, which are augmented by Bitstream Pattern Augmentation (BPA) and encoded with a shared ByteFormer backbone. The model is optimized with both classification and corruption consistency objectives. Specifically, we propose Bitstream Pattern Augmentation (BPA), which reshapes one-dimensional byte sequences into two-dimensional byte matrix and applies region-level erasure to encourage the model to learn robust cross-region byte dependencies. We further propose a Corruption Consistency Training strategy that constrains the model to maintain stable predictions across different corruption severities through bidirectional KL divergence. Experiments on the image bitstream from Stanford40, PPMI, and PASCAL VOC 2012 Action demonstrate that ByteAction achieves state-of-the-art corruption robustness across all scenarios while maintaining competitive intact bitstream performance.

cs.CV

Latent Ordinal Evidence, Misaligned Outputs: Inference-Time Ordinal Lens Alignment for Multimodal LLMs

Multimodal LLMs apply the language model interface to visual inputs, where ordinal regression tasks such as age estimation, image quality assessment, and disease grading require autoregressive decisions over ordered class labels. We ask whether MLLMs reliably convert internal ordinal evidence into ordered digit-token outputs. Across four ordinal benchmarks and four MLLM backbones, ordinal labels are linearly recoverable from hidden states with Spearman correlation up to 0.938, and a task-designed prompt further sharpens this structure. Yet native digit-token outputs weakly expose it: the unembedding matrix filters the ordinal direction, and the digit-token row space retains below 1.15% across all 16 model-dataset combinations, with a 16 to 77 absolute-point accuracy gap between linear-probe and native outputs. We introduce Ordinal Lens Alignment (OLA), a frozen-backbone inference-time method that trains lightweight W_S-anchored lenses on mid-to-deep decoder layers, fuses them into an ordinal distribution, and corrects only digit-token logits at generation. OLA outperforms the SOTA LoRA-tuned OrderChain baseline in most settings while keeping the MLLM frozen, surpasses discriminative ordinal baselines in most cells, and improves over an offline lens in every setting.

cs.CV

Unlocking the Power of Medical Tabular Data via Semantic-Aware Multimodal Pre-training

While vision-language models dominate medical representation learning, unstructured text lacks the dense, quantitative diagnostic phenotypes inherent in structured clinical tables. However, existing multimodal pre-training methods underutilize this potential due to semantic-agnostic designs that treat tabular inputs as flat vectors and employ unstable continuous regression objectives. To overcome this, we propose a novel semantic-aware framework explicitly modeling the intrinsic two-dimensional structure of tabular data. First, addressing the inter-feature hierarchy of varying diagnostic importance, we introduce Importance-Aware Adaptive Masking to construct a label-free curriculum prioritizing salient features. Second, addressing the intra-feature continuity-discreteness duality, we propose a Soft-Label Discretized Module that replaces unstable numerical regression with stable distribution matching, thereby mathematically preserving ordinal relationships. Extensive experiments across large-scale dermatology (SLICE-3D, HOP) and ophthalmology (EyePACS) datasets establish a new state-of-the-art (SOTA), demonstrating exceptional robustness and cross-domain generalizability.

cs.CV

MambaLSTM: A Spatio-Temporal Framework for Enhanced Traffic Accident Risk Prediction

In traffic accident risk prediction, most studies overlook the extra noise that could be incorporated when fusing temporal features into spatial features, and some models struggle to capture global correlations among spatial regions. To address these challenges, we propose a novel traffic accident risk prediction framework named MambaLSTM. First, we develop a squeeze-and-excitation temporal feature fusion module to integrate temporal information without compromising spatio-temporal integrity. Second, we introduce a new patch embedding module for effectively capturing semantic relationships among spatially adjacent regions. Additionally, we introduce a Mamba block based on state-space models to model global spatial semantics in urban regions. Finally, we propose a MambaLSTM unit to efficiently capture long- and short-term temporal dependencies for identifying dynamic risk patterns. Extensive experiments on real-world datasets demonstrate the proposed model's superiority over state-of-the-art methods. The code is released at https://github.com/Zhenzovo/MambaLSTM.

cs.LG

Interpretable Machine Learning for Antepartum Prediction of Pregnancy-Associated Thrombotic Microangiopathy Using Routine Longitudinal Laboratory Data

Background: Pregnancy-associated thrombotic microangiopathy (P-TMA) is rare but life-threatening. Early risk prediction before overt clinical presentation remains challenging, as the associated laboratory abnormalities are subtle, multidimensional, and frequently masked by common physiological changes such as gestational thrombocytopenia and pregnancy-related proteinuria, thus overlapping heavily with benign obstetric and renal conditions. This complexity is poorly captured by univariate or rule-based approaches; however, it is addressable by machine learning, which can extract latent, time-dependent risk signatures from longitudinal clinical tests. Methods: This retrospective study included 300 pregnancies comprising 142 P-TMA cases and 158 controls. After exclusion of identifiers and non-informative variables, 146 longitudinal laboratory predictors were retained. Participants were divided into a training cohort (80%) and a held-out test cohort (20%) using stratified sampling. Five algorithms were evaluated: logistic regression, support vector machine with radial basis function kernel, random forest, extra trees, and gradient boosting. The final model was selected by mean cross-validated AUROC, refitted on the full training cohort, and evaluated once in the held-out test cohort. Interpretability analyses examined global feature importance and distributional patterns of leading predictors. Results: Gradient boosting was prespecified by cross-validation in the training cohort. The model achieved an AUROC of 0.872 (95% CI: 0.769-0.952) and an AUPRC of 0.883 (95% CI: 0.780-0.959) in a held-out test cohort, with sensitivity of 0.750 and specificity of 0.812. Conclusions: Longitudinal clinical laboratory tests obtained during routine care contained informative and clinically plausible signals for P-TMA risk. Notably, cystatin C at week 6 showed promise as an early monitoring indicator.

cs.LG

Magnetism and Correlated Electrons in LaCr$_2$Ge$_2$N

We report the synthesis, structure and physical properties of a new quaternary nitride LaCr$_2$Ge$_2$N. The compound crystallizes in the CeCr$_2$Si$_2$C-type structure (P4/mmm), featuring distinctive Cr$_2$N square sheets within Cr$_2$Ge$_2$N block layers. Physical characterizations reveal enhanced electron correlations evidenced by a Sommerfeld coefficient substantially larger than band calculations and pressure-induced deviation from Fermi-liquid behavior. Magnetic measurements show short-range antiferromagnetic correlations developing around 460 K, followed by long-range magnetic ordering at 14 K. Additionally, subtle anomalies at 378 K suggest possible electronic ordering. First-principles calculations reveal nearly-flat Cr-3d bands near the Fermi level and predict a striped antiferromagnetic ground state. This work demonstrates how electron count variation in the CeCr$_2$Si$_2$C-type structure family leads to magnetic ordering in LaCr$_2$Ge$_2$N, contrasting with the paramagnetic behavior of LnCr$_2$Si$_2$C compounds.

cond-mat.str-el

RetinaGuard: Obfuscating Retinal Age in Fundus Images for Biometric Privacy Preserving

The integration of AI with medical images enables the extraction of implicit image-derived biomarkers for a precise health assessment. Recently, retinal age, a biomarker predicted from fundus images, is a proven predictor of systemic disease risks, behavioral patterns, aging trajectory and even mortality. However, the capability to infer such sensitive biometric data raises significant privacy risks, where unauthorized use of fundus images could lead to bioinformation leakage, breaching individual privacy. In response, we formulate a new research problem of biometric privacy associated with medical images and propose RetinaGuard, a novel privacy-enhancing framework that employs a feature-level generative adversarial masking mechanism to obscure retinal age while preserving image visual quality and disease diagnostic utility. The framework further utilizes a novel multiple-to-one knowledge distillation strategy incorporating a retinal foundation model and diverse surrogate age encoders to enable a universal defense against black-box age prediction models. Comprehensive evaluations confirm that RetinaGuard successfully obfuscates retinal age prediction with minimal impact on image quality and pathological feature representation. RetinaGuard is also flexible for extension to other medical image derived biomarkers. RetinaGuard is also flexible for extension to other medical image biomarkers.

cs.CV

Controllable Skin Synthesis via Lesion-Focused Vector Autoregression Model

Skin images from real-world clinical practice are often limited, resulting in a shortage of training data for deep-learning models. While many studies have explored skin image synthesis, existing methods often generate low-quality images and lack control over the lesion's location and type. To address these limitations, we present LF-VAR, a model leveraging quantified lesion measurement scores and lesion type labels to guide the clinically relevant and controllable synthesis of skin images. It enables controlled skin synthesis with specific lesion characteristics based on language prompts. We train a multiscale lesion-focused Vector Quantised Variational Auto-Encoder (VQVAE) to encode images into discrete latent representations for structured tokenization. Then, a Visual AutoRegressive (VAR) Transformer trained on tokenized representations facilitates image synthesis. Lesion measurement from the lesion region and types as conditional embeddings are integrated to enhance synthesis fidelity. Our method achieves the best overall FID score (average 0.74) among seven lesion types, improving upon the previous state-of-the-art (SOTA) by 6.3%. The study highlights our controllable skin synthesis model's effectiveness in generating high-fidelity, clinically relevant synthetic skin images. Our framework code is available at https://github.com/echosun1996/LF-VAR.

cs.CV

FedAPTA: Federated Multi-task Learning for Heterogeneous Devices with Adaptive Layer-wise Pruning and Task-aware Aggregation

Federated Learning (FL) has shown considerable promise in Machine Learning (ML) across numerous devices for privacy protection, efficient data utilization, and dynamic collaboration. However, mobile devices typically have limited and heterogeneous computational capabilities, and different devices may even have different tasks. This client heterogeneity is a major bottleneck hindering the practical application of FL. Existing work mainly focuses on mitigating FL's computation and communication overhead of a single task while overlooking the computing resource heterogeneity issue of different devices in FL. To tackle this, we design FedAPTA, a federated multi-task learning framework. FedAPTA overcomes computing resource heterogeneity through the developed layer-wise model pruning technique, which reduces local model size while considering both data and device heterogeneity. To aggregate structurally heterogeneous local models of different tasks, we introduce a heterogeneous model recovery strategy and a task-aware model aggregation method that enables the aggregation through infilling local model architecture with the shared global model and clustering local models according to their specific tasks. We deploy FedAPTA on a realistic FL platform and benchmark it against nine SOTA FL methods. The experimental outcomes demonstrate that the proposed FedAPTA considerably outperforms the state-of-the-art FL methods by up to 4.23\%. Our code is available at https://github.com/Zhenzovo/FedAPTA.

cs.DC

MAKE: Multi-Aspect Knowledge-Enhanced Vision-Language Pretraining for Zero-shot Dermatological Assessment

Dermatological diagnosis represents a complex multimodal challenge that requires integrating visual features with specialized clinical knowledge. While vision-language pretraining (VLP) has advanced medical AI, its effectiveness in dermatology is limited by text length constraints and the lack of structured texts. In this paper, we introduce MAKE, a Multi-Aspect Knowledge-Enhanced vision-language pretraining framework for zero-shot dermatological tasks. Recognizing that comprehensive dermatological descriptions require multiple knowledge aspects that exceed standard text constraints, our framework introduces: (1) a multi-aspect contrastive learning strategy that decomposes clinical narratives into knowledge-enhanced sub-texts through large language models, (2) a fine-grained alignment mechanism that connects subcaptions with diagnostically relevant image features, and (3) a diagnosis-guided weighting scheme that adaptively prioritizes different sub-captions based on clinical significance prior. Through pretraining on 403,563 dermatological image-text pairs collected from education resources, MAKE significantly outperforms state-of-the-art VLP models on eight datasets across zero-shot skin disease classification, concept annotation, and cross-modal retrieval tasks. Our code will be made publicly available at https: //github.com/SiyuanYan1/MAKE.

cs.CV

scDD: Latent Codes Based scRNA-seq Dataset Distillation with Foundation Model Knowledge

Single-cell RNA sequencing (scRNA-seq) technology has profiled hundreds of millions of human cells across organs, diseases, development and perturbations to date. However, the high-dimensional sparsity, batch effect noise, category imbalance, and ever-increasing data scale of the original sequencing data pose significant challenges for multi-center knowledge transfer, data fusion, and cross-validation between scRNA-seq datasets. To address these barriers, (1) we first propose a latent codes-based scRNA-seq dataset distillation framework named scDD, which transfers and distills foundation model knowledge and original dataset information into a compact latent space and generates synthetic scRNA-seq dataset by a generator to replace the original dataset. Then, (2) we propose a single-step conditional diffusion generator named SCDG, which perform single-step gradient back-propagation to help scDD optimize distillation quality and avoid gradient decay caused by multi-step back-propagation. Meanwhile, SCDG ensures the scRNA-seq data characteristics and inter-class discriminability of the synthetic dataset through flexible conditional control and generation quality assurance. Finally, we propose a comprehensive benchmark to evaluate the performance of scRNA-seq dataset distillation in different data analysis tasks. It is validated that our proposed method can achieve 7.61% absolute and 15.70% relative improvement over previous state-of-the-art methods on average task.

cs.LG

RoadFed: A Multimodal Federated Learning System for Improving Road Safety

Internet of Things (IoTs) have been widely applied in Collaborative Intelligent Transportation Systems (C-ITS) for the prevention of road accidents. As one of the primary causes of road accidents in C-ITS, the efficient detection and early alarm of road hazards are of paramount importance. Given the importance, extensive research has explored this topic and obtained favorable results. However, most existing solutions only explore single-modality data, struggle with high computation and communication overhead, or suffer from the curse of high dimensionality in their privacy-preserving methodologies. To overcome these obstacles, in this paper, we introduce RoadFed, an innovative and private multimodal Federated learning-based system tailored for intelligent Road hazard detection and alarm. This framework encompasses an innovative Multimodal Road Hazard Detector, a communication-efficient federated learning approach, and a customized low-error-rate local differential privacy method crafted for high dimensional multimodal data. Experimental results reveal that the proposed RoadFed surpasses most existing systems in the self-gathered real-world and CrisisMMD public datasets. In particular, RoadFed achieves an accuracy of 96.42% with a mere 0.0351 seconds of latency and its communication cost is up to 1,000 times lower than existing systems in this field. It facilitates collaborative training with non-iid high dimensional multimodal real-world data across various data modalities on multiple edges while ensuring privacy preservation for road users.

cs.CE

CtrlNeRF: The Generative Neural Radiation Fields for the Controllable Synthesis of High-fidelity 3D-Aware Images

The neural radiance field (NERF) advocates learning the continuous representation of 3D geometry through a multilayer perceptron (MLP). By integrating this into a generative model, the generative neural radiance field (GRAF) is capable of producing images from random noise z without 3D supervision. In practice, the shape and appearance are modeled by z_s and z_a, respectively, to manipulate them separately during inference. However, it is challenging to represent multiple scenes using a solitary MLP and precisely control the generation of 3D geometry in terms of shape and appearance. In this paper, we introduce a controllable generative model (i.e. \textbf{CtrlNeRF}) that uses a single MLP network to represent multiple scenes with shared weights. Consequently, we manipulated the shape and appearance codes to realize the controllable generation of high-fidelity images with 3D consistency. Moreover, the model enables the synthesis of novel views that do not exist in the training sets via camera pose alteration and feature interpolation. Extensive experiments were conducted to demonstrate its superiority in 3D-aware image generation compared to its counterparts.

cs.CV

A Multimodal Vision Foundation Model for Clinical Dermatology

Diagnosing and treating skin diseases require advanced visual skills across domains and the ability to synthesize information from multiple imaging modalities. While current deep learning models excel at specific tasks like skin cancer diagnosis from dermoscopic images, they struggle to meet the complex, multimodal requirements of clinical practice. Here, we introduce PanDerm, a multimodal dermatology foundation model pretrained through self-supervised learning on over 2 million real-world skin disease images from 11 clinical institutions across 4 imaging modalities. We evaluated PanDerm on 28 diverse benchmarks, including skin cancer screening, risk stratification, differential diagnosis of common and rare skin conditions, lesion segmentation, longitudinal monitoring, and metastasis prediction and prognosis. PanDerm achieved state-of-the-art performance across all evaluated tasks, often outperforming existing models when using only 10% of labeled data. We conducted three reader studies to assess PanDerm's potential clinical utility. PanDerm outperformed clinicians by 10.2% in early-stage melanoma detection through longitudinal analysis, improved clinicians' skin cancer diagnostic accuracy by 11% on dermoscopy images, and enhanced non-dermatologist healthcare providers' differential diagnosis by 16.5% across 128 skin conditions on clinical photographs. These results demonstrate PanDerm's potential to improve patient care across diverse clinical scenarios and serve as a model for developing multimodal foundation models in other medical specialties, potentially accelerating the integration of AI support in healthcare. The code can be found at https://github.com/SiyuanYan1/PanDerm.

cs.CV

Adaptive Transformer Modelling of Density Function for Nonparametric Survival Analysis

Survival analysis holds a crucial role across diverse disciplines, such as economics, engineering and healthcare. It empowers researchers to analyze both time-invariant and time-varying data, encompassing phenomena like customer churn, material degradation and various medical outcomes. Given the complexity and heterogeneity of such data, recent endeavors have demonstrated successful integration of deep learning methodologies to address limitations in conventional statistical approaches. However, current methods typically involve cluttered probability distribution function (PDF), have lower sensitivity in censoring prediction, only model static datasets, or only rely on recurrent neural networks for dynamic modelling. In this paper, we propose a novel survival regression method capable of producing high-quality unimodal PDFs without any prior distribution assumption, by optimizing novel Margin-Mean-Variance loss and leveraging the flexibility of Transformer to handle both temporal and non-temporal data, coined UniSurv. Extensive experiments on several datasets demonstrate that UniSurv places a significantly higher emphasis on censoring compared to other methods.

cs.LG

Enhancing Vision-Language Models Generalization via Diversity-Driven Novel Feature Synthesis

Vision-language foundation models like CLIP have shown impressive zero-shot generalization, but finetuning on downstream datasets can cause overfitting and loss of its generalization ability on unseen domains. Although collecting additional data from new domains of interest is possible, this method is often impractical due to the challenges in obtaining annotated data. To address this, we propose a plug-and-play feature synthesis method called LDFS (Language-Guided Diverse Feature Synthesis) to synthesize new domain features and improve existing CLIP fine-tuning strategies. LDFS has three main contributions: 1) To synthesize novel domain features and promote diversity, we propose an instance-conditional feature augmentation strategy based on a text-guided feature augmentation loss. 2) To maintain feature quality after augmenting, we introduce a pairwise regularizer to preserve augmented feature coherence within the CLIP feature space. 3) We propose to use stochastic text feature augmentation to reduce the modality gap and further facilitate the process of text-guided feature synthesis. Extensive experiments show LDFS superiority in improving CLIP generalization ability on unseen domains without collecting data from those domains. The code will be made publicly available.

cs.CV

Progressive trajectory matching for medical dataset distillation

It is essential but challenging to share medical image datasets due to privacy issues, which prohibit building foundation models and knowledge transfer. In this paper, we propose a novel dataset distillation method to condense the original medical image datasets into a synthetic one that preserves useful information for building an analysis model without accessing the original datasets. Existing methods tackle only natural images by randomly matching parts of the training trajectories of the model parameters trained by the whole real datasets. However, through extensive experiments on medical image datasets, the training process is extremely unstable and achieves inferior distillation results. To solve these barriers, we propose to design a novel progressive trajectory matching strategy to improve the training stability for medical image dataset distillation. Additionally, it is observed that improved stability prevents the synthetic dataset diversity and final performance improvements. Therefore, we propose a dynamic overlap mitigation module that improves the synthetic dataset diversity by dynamically eliminating the overlap across different images and retraining parts of the synthetic images for better convergence. Finally, we propose a new medical image dataset distillation benchmark of various modalities and configurations to promote fair evaluations. It is validated that our proposed method achieves 8.33% improvement over previous state-of-the-art methods on average, and 11.7% improvement when ipc=2 (i.e., image per class is 2). Codes and benchmarks will be released.

cs.CV

Prompt-driven Latent Domain Generalization for Medical Image Classification

Deep learning models for medical image analysis easily suffer from distribution shifts caused by dataset artifacts bias, camera variations, differences in the imaging station, etc., leading to unreliable diagnoses in real-world clinical settings. Domain generalization (DG) methods, which aim to train models on multiple domains to perform well on unseen domains, offer a promising direction to solve the problem. However, existing DG methods assume domain labels of each image are available and accurate, which is typically feasible for only a limited number of medical datasets. To address these challenges, we propose a novel DG framework for medical image classification without relying on domain labels, called Prompt-driven Latent Domain Generalization (PLDG). PLDG consists of unsupervised domain discovery and prompt learning. This framework first discovers pseudo domain labels by clustering the bias-associated style features, then leverages collaborative domain prompts to guide a Vision Transformer to learn knowledge from discovered diverse domains. To facilitate cross-domain knowledge learning between different prompts, we introduce a domain prompt generator that enables knowledge sharing between domain prompts and a shared prompt. A domain mixup strategy is additionally employed for more flexible decision margins and mitigates the risk of incorrect domain assignments. Extensive experiments on three medical image classification tasks and one debiasing task demonstrate that our method can achieve comparable or even superior performance than conventional DG algorithms without relying on domain labels. Our code will be publicly available upon the paper is accepted.

eess.IV