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Zhihao Wu

Publications and source records attributed to Zhihao Wu.

At least 19 recordsLinked to original sources

Pretraining Reusable Inference Across Views with Synthetic Task Priors

Modern pretrained encoders make representations from heterogeneous views increasingly reusable, but the procedure that determines view utility and combines evidence is still relearned for each downstream task. Consequently, knowledge about view relevance, complementarity, reliability, and missingness is repeatedly discarded rather than transferred across tasks. We therefore reformulate multi-view learning as learning a reusable, task-conditioned inference procedure rather than a fixed fusion function. Based on this perspective, we propose SIMPLE, a prior-fitted multi-view in-context learner that predicts query labels by conditioning on a small labeled support set. Since existing real-world datasets cover only a limited range of view configurations and task structures, we construct a controllable synthetic task prior in embedding space. It generates diverse support-query episodes with varying class structures, shared and view-specific factors, representation geometries, cross-view dependencies, reliability levels, missingness patterns, and distribution shifts. A hierarchical inference architecture then performs reasoning within views, across views, and across support and query samples. Experiments on multi-view and multi-omics benchmarks demonstrate that the frozen variant of SIMPLE achieves competitive performance without updating the inference backbone, while lightweight adapter calibration attains leading performance on most evaluated datasets. Together, the results under frozen, one-shot, and missing-view settings support the central hypothesis that multi-view reasoning itself can be pretrained and reused, while lightweight adapter calibration provides task-specific alignment when needed.

cs.LG

FedTopo: Relation-Level Topology Sharing for Model-Heterogeneous Federated Learning

Federated learning (FL) enables collaborative learning over decentralized data silos without centralizing raw data. However, heterogeneous local architectures often induce non-aligned representation spaces, making it difficult to transfer global knowledge across silos. Existing paradigms share this knowledge as model parameters, distilled predictions, or class prototypes, yet all encode it in an absolute space that must be aligned across clients. Heterogeneous backbones break this alignment, so the shared knowledge becomes unreliable and misleads local training. We propose FedTopo, a relation-level framework that encodes global knowledge as class relation topology, capturing how classes relate within each client rather than where they lie in feature space. Each client builds its relation topology from local prototypes and uploads it with class statistics. The server then aggregates these relations in a reliability-aware manner that down-weights weakly supported ones, and broadcasts the global topology to clients. The global topology guides local training by emphasizing topology-similar negative classes. Experiments on three datasets under eight heterogeneous backbones show that FedTopo consistently outperforms parameter-, distillation-, and prototype-sharing baselines, with low communication and no inference overhead. Our code is available at https://github.com/Zhaoyang-Ma/FedTopo.

cs.LG

DeepBD: A Grounded Agentic Workflow for Variant Prioritization and Diagnosis of Genetic Birth Defects

Birth defects are a major cause of fetal loss, neonatal morbidity and long-term disability. In the subset with suspected genetic etiologies, exome and genome sequencing have moved many cases from variant detection to post-sequencing interpretation: clinicians must rank patient-specific candidate variants under incomplete fetal or infant phenotypes and heterogeneous evidence from population genetics, variant-effect prediction, gene-disease validity, phenotype ontologies, cellular and pathway context, protein structure and clinical literature. We present DeepBD, a grounded agentic workflow for variant prioritization and diagnostic interpretation of genetic birth defects. DeepBD organizes the workflow into LLM-assisted case structuring, a pretrained evidence engine, specialist evidence modules and a grounded diagnostic review layer. The evidence engine learns patient-specific variant scores from structured rule evidence, sequence and variant-effect representations and phenotype-conditioned biological context, whereas specialist modules and the agentic layer provide tool-based refinement, candidate-pool review and diagnosis-oriented synthesis from ranked candidates. Developed using an in-house fetal and infant cohort comprising 18,622 cases, DeepBD achieved Recall@1/3/5/10 of 0.658/0.882/0.912/0.929 on an internal held-out solved-case benchmark, outperforming standalone Exomiser, DeepRare and prompted LLM reranking baselines evaluated on Exomiser-derived top-20 candidate variants. Ablation and overlap analyses show that rule evidence, mechanistic context, and specialist refinement provide complementary signals. These findings support a grounded agentic workflow that separates evidence integration, tool-based refinement, and LLM-assisted diagnostic review for retrospective variant prioritization in genetic birth defects.

q-bio.GN

EDIT: Evidence-Diagnosed Intervention Training for Rule-Faithful LLM Grading

Reliable rubric grading requires more than accurate score prediction. Each judgement must be grounded in the mark scheme and evidence from the student answer. Existing credit-assignment and intervention methods, primarily designed for self-contained reasoning tasks such as mathematics reasoning, struggle in this setting because they do not identify where grading reasoning goes wrong or how the model's belief about the final mark changes during reasoning. We propose Evidence-Diagnosed Intervention Training (EDIT), a two-phase framework for training more rubric-faithful LLM graders. First, EDIT-SFT locates problematic reasoning steps using internal model signals: posterior belief over the final mark and input-grounding scores. It then revises only these local steps with help from a rubric checklist. Second, EDIT-RL calibrates the grader with belief-guided reward shaping, penalising large harmful belief drifts while still allowing helpful exploration. Experiments on two real-world, multi-subject grading benchmarks demonstrate that EDIT consistently outperforms strong supervised fine-tuning and reinforcement learning baselines on both in-domain and out-of-domain splits, with ablation studies confirming that internal-state diagnostics drive these gains. Under deterministic rubric-edit interventions, EDIT-SFT is the most rule-responsive of all evaluated systems, and EDIT-RL largely retains this responsiveness while improving accuracy.

cs.CL

Linear Ensembles Wash Away Watermarks: On the Fragility of Distributional Perturbations in LLMs

Watermarking embeds statistical signatures in AI-generated text for detection and attribution. We reveal a fundamental vulnerability: when users access multiple models (today's reality), watermarks trivially fail. Watermarks perturb output distributions away from the original, and in competitive markets, these perturbations are typically independent across providers. We theoretically prove that averaging output probability distributions recovers the unwatermarked distribution with up to a second-order error term. Empirically, simply averaging 3-5 models cancels out these perturbations. We introduce WASH (Watermark Attenuation via Statistical Hybridisation), which solves practical challenges in ensemble generation: vocabulary misalignment and tokenisation differences across heterogeneous models. Experiments across six watermarking schemes and three LLMs show that averaging across 3 models suppresses detection z-scores from 5-300 to below 2 (below the detection threshold of 4) and reduces TPR at 5% FPR to below 50%, while improving quality by 27.5% and running 6 times faster than the best baseline on the long sequence generation. Our results suggest that robust AI-text detection via watermarking requires either accepting this fundamental vulnerability or unprecedented coordination among model providers.

cs.CL

Systematic Characterization of Transmon Qubit Stability with Thermal Cycling

The temporal stability and reproducibility of qubit parameters are critical for the long-term operation and maintenance of superconducting quantum processors. In this work, we present a comprehensive longitudinal characterization of 27 frequency-tunable transmon qubits spanning over one year across four thermal cycles. Our results establish a distinct hierarchy of stability for superconducting hardware. We find that the intrinsic device parameters determining the qubit frequency and the baseline energy relaxation times ($T_1$) exhibit high robustness against thermal stress, characterized by frequency deviations typically confined within 0.5\% and non-degraded coherence baselines. In stark contrast, the environmental variables, specifically the background magnetic flux offsets and the microscopic landscape of two-level system (TLS) defects, undergo a significant stochastic reconfiguration after each cycle. By employing frequency-dependent relaxation spectroscopy and a quantitative metric, the $T_1$ Spectral Topography Fidelity, we demonstrate that thermal cycling acts as a ``hard reset'' for the local defect environment. This process introduces a level of spectral randomization equivalent to thousands of hours of continuous low-temperature evolution. These findings confirm that while the fabrication quality is preserved, the specific noise realization is statistically distinct for each thermal cycle, necessitating automated recalibration strategies for large-scale quantum systems.

quant-ph

MMPG: MoE-based Adaptive Multi-Perspective Graph Fusion for Protein Representation Learning

Graph Neural Networks (GNNs) have been widely adopted for Protein Representation Learning (PRL), as residue interaction networks can be naturally represented as graphs. Current GNN-based PRL methods typically rely on single-perspective graph construction strategies, which capture partial properties of residue interactions, resulting in incomplete protein representations. To address this limitation, we propose MMPG, a framework that constructs protein graphs from multiple perspectives and adaptively fuses them via Mixture of Experts (MoE) for PRL. MMPG constructs graphs from physical, chemical, and geometric perspectives to characterize different properties of residue interactions. To capture both perspective-specific features and their synergies, we develop an MoE module, which dynamically routes perspectives to specialized experts, where experts learn intrinsic features and cross-perspective interactions. We quantitatively verify that MoE automatically specializes experts in modeling distinct levels of interaction from individual representations, to pairwise inter-perspective synergies, and ultimately to a global consensus across all perspectives. Through integrating this multi-level information, MMPG produces superior protein representations and achieves advanced performance on four different downstream protein tasks.

cs.AI

Multi-Omics Analysis for Cancer Subtype Inference via Unrolling Graph Smoothness Priors

Integrating multi-omics datasets through data-driven analysis offers a comprehensive understanding of the complex biological processes underlying various diseases, particularly cancer. Graph Neural Networks (GNNs) have recently demonstrated remarkable ability to exploit relational structures in biological data, enabling advances in multi-omics integration for cancer subtype classification. Existing approaches often neglect the intricate coupling between heterogeneous omics, limiting their capacity to resolve subtle cancer subtype heterogeneity critical for precision oncology. To address these limitations, we propose a framework named Graph Transformer for Multi-omics Cancer Subtype Classification (GTMancer). This framework builds upon the GNN optimization problem and extends its application to complex multi-omics data. Specifically, our method leverages contrastive learning to embed multi-omics data into a unified semantic space. We unroll the multiplex graph optimization problem in that unified space and introduce dual sets of attention coefficients to capture structural graph priors both within and among multi-omics data. This approach enables global omics information to guide the refining of the representations of individual omics. Empirical experiments on seven real-world cancer datasets demonstrate that GTMancer outperforms existing state-of-the-art algorithms.

cs.LG

AgentSwift: Efficient LLM Agent Design via Value-guided Hierarchical Search

Large language model (LLM) agents have demonstrated strong capabilities across diverse domains, yet automated agent design remains a significant challenge. Current automated agent design approaches are often constrained by limited search spaces that primarily optimize workflows but fail to integrate crucial human-designed components like memory, planning, and tool use. Furthermore, these methods are hampered by high evaluation costs, as evaluating even a single new agent on a benchmark can require tens of dollars. The difficulty of this exploration is further exacerbated by inefficient search strategies that struggle to navigate the large design space effectively, making the discovery of novel agents a slow and resource-intensive process. To address these challenges, we propose AgentSwift, a novel framework for automated agent design. We formalize a hierarchical search space that jointly models agentic workflow and composable functional components. This structure moves beyond optimizing workflows alone by co-optimizing functional components, which enables the discovery of more complex and effective agent architectures. To make exploration within this expansive space feasible, we mitigate high evaluation costs by training a value model on a high-quality dataset, generated via a novel strategy combining combinatorial coverage and balanced Bayesian sampling for low-cost evaluation. Guiding the entire process is a hierarchical MCTS strategy, which is informed by uncertainty to efficiently navigate the search space. Evaluated across a comprehensive set of seven benchmarks spanning embodied, math, web, tool, and game domains, AgentSwift discovers agents that achieve an average performance gain of 8.34\% over both existing automated agent search methods and manually designed agents. Our framework serves as a launchpad for researchers to rapidly discover powerful agent architectures.

cs.CL

Harmonizing Intra-coherence and Inter-divergence in Ensemble Attacks for Adversarial Transferability

The development of model ensemble attacks has significantly improved the transferability of adversarial examples, but this progress also poses severe threats to the security of deep neural networks. Existing methods, however, face two critical challenges: insufficient capture of shared gradient directions across models and a lack of adaptive weight allocation mechanisms. To address these issues, we propose a novel method Harmonized Ensemble for Adversarial Transferability (HEAT), which introduces domain generalization into adversarial example generation for the first time. HEAT consists of two key modules: Consensus Gradient Direction Synthesizer, which uses Singular Value Decomposition to synthesize shared gradient directions; and Dual-Harmony Weight Orchestrator which dynamically balances intra-domain coherence, stabilizing gradients within individual models, and inter-domain diversity, enhancing transferability across models. Experimental results demonstrate that HEAT significantly outperforms existing methods across various datasets and settings, offering a new perspective and direction for adversarial attack research.

cs.LG

Simplifying Graph Convolutional Networks with Redundancy-Free Neighbors

In recent years, Graph Convolutional Networks (GCNs) have gained popularity for their exceptional ability to process graph-structured data. Existing GCN-based approaches typically employ a shallow model architecture due to the over-smoothing phenomenon. Current approaches to mitigating over-smoothing primarily involve adding supplementary components to GCN architectures, such as residual connections and random edge-dropping strategies. However, these improvements toward deep GCNs have achieved only limited success. In this work, we analyze the intrinsic message passing mechanism of GCNs and identify a critical issue: messages originating from high-order neighbors must traverse through low-order neighbors to reach the target node. This repeated reliance on low-order neighbors leads to redundant information aggregation, a phenomenon we term over-aggregation. Our analysis demonstrates that over-aggregation not only introduces significant redundancy but also serves as the fundamental cause of over-smoothing in GCNs.

cs.LG

Error-mitigated entanglement-assisted quantum process tomography

In the era of noisy intermediate-scale quantum computing, it is of crucial importance to verify quantum processes and extract information. Quantum process tomography is a typical approach, however, both resource-intensive and vulnerable to state preparation and measurement errors. Here, we propose an error-mitigated entanglement-assisted quantum process tomography (EM-EAPT) framework to address these limitations. By leveraging a maximally entangled state to reduce state preparation complexity and integrating error mitigation techniques, our method significantly enhances robustness against SPAM errors. Experimental validation on a superconducting processor demonstrates the efficacy of EM-EAPT for two-qubit and three-qubit quantum processes. Results show more accurate average gate fidelities close to the realistic estimation, achieving 98.1$\pm$ 0.03% for a CNOT gate and 88.1%$\pm$ 0.04% for a cascaded CNOT process after error mitigation, compared to non-mitigated implementations. This work advances practical quantum verification tools for NISQ devices, enabling higher-fidelity characterization of quantum processes under realistic noise conditions.

quant-ph

AppVLM: A Lightweight Vision Language Model for Online App Control

The utilisation of foundation models as smartphone assistants, termed app agents, is a critical research challenge. These agents aim to execute human instructions on smartphones by interpreting textual instructions and performing actions via the device's interface. While promising, current approaches face significant limitations. Methods that use large proprietary models, such as GPT-4o, are computationally expensive, while those that use smaller fine-tuned models often lack adaptability to out-of-distribution tasks. In this work, we introduce AppVLM, a lightweight Vision-Language Model (VLM). First, we fine-tune it offline on the AndroidControl dataset. Then, we refine its policy by collecting data from the AndroidWorld environment and performing further training iterations. Our results indicate that AppVLM achieves the highest action prediction accuracy in offline evaluation on the AndroidControl dataset, compared to all evaluated baselines, and matches GPT-4o in online task completion success rate in the AndroidWorld environment, while being up to ten times faster. This makes AppVLM a practical and efficient solution for real-world deployment.

cs.AI

OCMDP: Observation-Constrained Markov Decision Process

In many practical applications, decision-making processes must balance the costs of acquiring information with the benefits it provides. Traditional control systems often assume full observability, an unrealistic assumption when observations are expensive. We tackle the challenge of simultaneously learning observation and control strategies in such cost-sensitive environments by introducing the Observation-Constrained Markov Decision Process (OCMDP), where the policy influences the observability of the true state. To manage the complexity arising from the combined observation and control actions, we develop an iterative, model-free deep reinforcement learning algorithm that separates the sensing and control components of the policy. This decomposition enables efficient learning in the expanded action space by focusing on when and what to observe, as well as determining optimal control actions, without requiring knowledge of the environment's dynamics. We validate our approach on a simulated diagnostic task and a realistic healthcare environment using HeartPole. Given both scenarios, the experimental results demonstrate that our model achieves a substantial reduction in observation costs on average, significantly outperforming baseline methods by a notable margin in efficiency.

cs.AI

SPA-Bench: A Comprehensive Benchmark for SmartPhone Agent Evaluation

Smartphone agents are increasingly important for helping users control devices efficiently, with (Multimodal) Large Language Model (MLLM)-based approaches emerging as key contenders. Fairly comparing these agents is essential but challenging, requiring a varied task scope, the integration of agents with different implementations, and a generalisable evaluation pipeline to assess their strengths and weaknesses. In this paper, we present SPA-Bench, a comprehensive SmartPhone Agent Benchmark designed to evaluate (M)LLM-based agents in an interactive environment that simulates real-world conditions. SPA-Bench offers three key contributions: (1) A diverse set of tasks covering system and third-party apps in both English and Chinese, focusing on features commonly used in daily routines; (2) A plug-and-play framework enabling real-time agent interaction with Android devices, integrating over ten agents with the flexibility to add more; (3) A novel evaluation pipeline that automatically assesses agent performance across multiple dimensions, encompassing seven metrics related to task completion and resource consumption. Our extensive experiments across tasks and agents reveal challenges like interpreting mobile user interfaces, action grounding, memory retention, and execution costs. We propose future research directions to ease these difficulties, moving closer to real-world smartphone agent applications. SPA-Bench is available at https://ai-agents-2030.github.io/SPA-Bench/.

cs.AI

DistRL: An Asynchronous Distributed Reinforcement Learning Framework for On-Device Control Agents

On-device control agents, especially on mobile devices, are responsible for operating mobile devices to fulfill users' requests, enabling seamless and intuitive interactions. Integrating Multimodal Large Language Models (MLLMs) into these agents enhances their ability to understand and execute complex commands, thereby improving user experience. However, fine-tuning MLLMs for on-device control presents significant challenges due to limited data availability and inefficient online training processes. This paper introduces DistRL, a novel framework designed to enhance the efficiency of online RL fine-tuning for mobile device control agents. DistRL employs centralized training and decentralized data acquisition to ensure efficient fine-tuning in the context of dynamic online interactions. Additionally, the framework is backed by our tailor-made RL algorithm, which effectively balances exploration with the prioritized utilization of collected data to ensure stable and robust training. Our experiments show that, on average, DistRL delivers a 3X improvement in training efficiency and enables training data collection 2.4X faster than the leading synchronous multi-machine methods. Notably, after training, DistRL achieves a 20% relative improvement in success rate compared to state-of-the-art methods on general Android tasks from an open benchmark, significantly outperforming existing approaches while maintaining the same training time. These results validate DistRL as a scalable and efficient solution, offering substantial improvements in both training efficiency and agent performance for real-world, in-the-wild device control tasks.

cs.LG

Masked Two-channel Decoupling Framework for Incomplete Multi-view Weak Multi-label Learning

Multi-view learning has become a popular research topic in recent years, but research on the cross-application of classic multi-label classification and multi-view learning is still in its early stages. In this paper, we focus on the complex yet highly realistic task of incomplete multi-view weak multi-label learning and propose a masked two-channel decoupling framework based on deep neural networks to solve this problem. The core innovation of our method lies in decoupling the single-channel view-level representation, which is common in deep multi-view learning methods, into a shared representation and a view-proprietary representation. We also design a cross-channel contrastive loss to enhance the semantic property of the two channels. Additionally, we exploit supervised information to design a label-guided graph regularization loss, helping the extracted embedding features preserve the geometric structure among samples. Inspired by the success of masking mechanisms in image and text analysis, we develop a random fragment masking strategy for vector features to improve the learning ability of encoders. Finally, it is important to emphasize that our model is fully adaptable to arbitrary view and label absences while also performing well on the ideal full data. We have conducted sufficient and convincing experiments to confirm the effectiveness and advancement of our model.

cs.CV

ADEdgeDrop: Adversarial Edge Dropping for Robust Graph Neural Networks

Although Graph Neural Networks (GNNs) have exhibited the powerful ability to gather graph-structured information from neighborhood nodes via various message-passing mechanisms, the performance of GNNs is limited by poor generalization and fragile robustness caused by noisy and redundant graph data. As a prominent solution, Graph Augmentation Learning (GAL) has recently received increasing attention. Among prior GAL approaches, edge-dropping methods that randomly remove edges from a graph during training are effective techniques to improve the robustness of GNNs. However, randomly dropping edges often results in bypassing critical edges, consequently weakening the effectiveness of message passing. In this paper, we propose a novel adversarial edge-dropping method (ADEdgeDrop) that leverages an adversarial edge predictor guiding the removal of edges, which can be flexibly incorporated into diverse GNN backbones. Employing an adversarial training framework, the edge predictor utilizes the line graph transformed from the original graph to estimate the edges to be dropped, which improves the interpretability of the edge-dropping method. The proposed ADEdgeDrop is optimized alternately by stochastic gradient descent and projected gradient descent. Comprehensive experiments on six graph benchmark datasets demonstrate that the proposed ADEdgeDrop outperforms state-of-the-art baselines across various GNN backbones, demonstrating improved generalization and robustness.

cs.LG