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At least 991 records · Page 55Linked to original sources

Cross-Modal Self-Attention Network for Referring Image Segmentation

We consider the problem of referring image segmentation. Given an input image and a natural language expression, the goal is to segment the object referred by the language expression in the image. Existing works in this area treat the language expression and the input image separately in their representations. They do not sufficiently capture long-range correlations between these two modalities. In this paper, we propose a cross-modal self-attention (CMSA) module that effectively captures the long-range dependencies between linguistic and visual features. Our model can adaptively focus on informative words in the referring expression and important regions in the input image. In addition, we propose a gated multi-level fusion module to selectively integrate self-attentive cross-modal features corresponding to different levels in the image. This module controls the information flow of features at different levels. We validate the proposed approach on four evaluation datasets. Our proposed approach consistently outperforms existing state-of-the-art methods.

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Modality-Agnostic Learning for Medical Image Segmentation Using Multi-modality Self-distillation

Medical image segmentation of tumors and organs at risk is a time-consuming yet critical process in the clinic that utilizes multi-modality imaging (e.g, different acquisitions, data types, and sequences) to increase segmentation precision. In this paper, we propose a novel framework, Modality-Agnostic learning through Multi-modality Self-dist-illation (MAG-MS), to investigate the impact of input modalities on medical image segmentation. MAG-MS distills knowledge from the fusion of multiple modalities and applies it to enhance representation learning for individual modalities. Thus, it provides a versatile and efficient approach to handle limited modalities during testing. Our extensive experiments on benchmark datasets demonstrate the high efficiency of MAG-MS and its superior segmentation performance than current state-of-the-art methods. Furthermore, using MAG-MS, we provide valuable insight and guidance on selecting input modalities for medical image segmentation tasks.

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Image Segmentation with Multidimensional Refinement Indicators

We transpose an optimal control technique to the image segmentation problem. The idea is to consider image segmentation as a parameter estimation problem. The parameter to estimate is the color of the pixels of the image. We use the adaptive parameterization technique which builds iteratively an optimal representation of the parameter into uniform regions that form a partition of the domain, hence corresponding to a segmentation of the image. We minimize an error function during the iterations, and the partition of the image into regions is optimally driven by the gradient of this error. The resulting segmentation algorithm inherits desirable properties from its optimal control origin: soundness, robustness, and flexibility.

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ReMamber: Referring Image Segmentation with Mamba Twister

Referring Image Segmentation~(RIS) leveraging transformers has achieved great success on the interpretation of complex visual-language tasks. However, the quadratic computation cost makes it resource-consuming in capturing long-range visual-language dependencies. Fortunately, Mamba addresses this with efficient linear complexity in processing. However, directly applying Mamba to multi-modal interactions presents challenges, primarily due to inadequate channel interactions for the effective fusion of multi-modal data. In this paper, we propose ReMamber, a novel RIS architecture that integrates the power of Mamba with a multi-modal Mamba Twister block. The Mamba Twister explicitly models image-text interaction, and fuses textual and visual features through its unique channel and spatial twisting mechanism. We achieve competitive results on three challenging benchmarks with a simple and efficient architecture. Moreover, we conduct thorough analyses of ReMamber and discuss other fusion designs using Mamba. These provide valuable perspectives for future research. The code has been released at: https://github.com/yyh-rain-song/ReMamber.

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UNet++: Redesigning Skip Connections to Exploit Multiscale Features in Image Segmentation

The state-of-the-art models for medical image segmentation are variants of U-Net and fully convolutional networks (FCN). Despite their success, these models have two limitations: (1) their optimal depth is apriori unknown, requiring extensive architecture search or inefficient ensemble of models of varying depths; and (2) their skip connections impose an unnecessarily restrictive fusion scheme, forcing aggregation only at the same-scale feature maps of the encoder and decoder sub-networks. To overcome these two limitations, we propose UNet++, a new neural architecture for semantic and instance segmentation, by (1) alleviating the unknown network depth with an efficient ensemble of U-Nets of varying depths, which partially share an encoder and co-learn simultaneously using deep supervision; (2) redesigning skip connections to aggregate features of varying semantic scales at the decoder sub-networks, leading to a highly flexible feature fusion scheme; and (3) devising a pruning scheme to accelerate the inference speed of UNet++. We have evaluated UNet++ using six different medical image segmentation datasets, covering multiple imaging modalities such as computed tomography (CT), magnetic resonance imaging (MRI), and electron microscopy (EM), and demonstrating that (1) UNet++ consistently outperforms the baseline models for the task of semantic segmentation across different datasets and backbone architectures; (2) UNet++ enhances segmentation quality of varying-size objects -- an improvement over the fixed-depth U-Net; (3) Mask RCNN++ (Mask R-CNN with UNet++ design) outperforms the original Mask R-CNN for the task of instance segmentation; and (4) pruned UNet++ models achieve significant speedup while showing only modest performance degradation. Our implementation and pre-trained models are available at https://github.com/MrGiovanni/UNetPlusPlus.

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Kernelized Weighted SUSAN based Fuzzy C-Means Clustering for Noisy Image Segmentation

The paper proposes a novel Kernelized image segmentation scheme for noisy images that utilizes the concept of Smallest Univalue Segment Assimilating Nucleus (SUSAN) and incorporates spatial constraints by computing circular colour map induced weights. Fuzzy damping coefficients are obtained for each nucleus or center pixel on the basis of the corresponding weighted SUSAN area values, the weights being equal to the inverse of the number of horizontal and vertical moves required to reach a neighborhood pixel from the center pixel. These weights are used to vary the contributions of the different nuclei in the Kernel based framework. The paper also presents an edge quality metric obtained by fuzzy decision based edge candidate selection and final computation of the blurriness of the edges after their selection. The inability of existing algorithms to preserve edge information and structural details in their segmented maps necessitates the computation of the edge quality factor (EQF) for all the competing algorithms. Qualitative and quantitative analysis have been rendered with respect to state-of-the-art algorithms and for images ridden with varying types of noises. Speckle noise ridden SAR images and Rician noise ridden Magnetic Resonance Images have also been considered for evaluating the effectiveness of the proposed algorithm in extracting important segmentation information.

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An Unsupervised Ensemble-based Markov Random Field Approach to Microscope Cell Image Segmentation

In this paper, we propose an approach to the unsupervised segmentation of images using Markov Random Field. The proposed approach is based on the idea of Bit Plane Slicing. We use the planes as initial labellings for an ensemble of segmentations. With pixelwise voting, a robust segmentation approach can be achieved, which we demonstrate on microscope cell images. We tested our approach on a publicly available database, where it proven to be competitive with other methods and manual segmentation.

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Enhancing MR Image Segmentation with Realistic Adversarial Data Augmentation

The success of neural networks on medical image segmentation tasks typically relies on large labeled datasets for model training. However, acquiring and manually labeling a large medical image set is resource-intensive, expensive, and sometimes impractical due to data sharing and privacy issues. To address this challenge, we propose AdvChain, a generic adversarial data augmentation framework, aiming at improving both the diversity and effectiveness of training data for medical image segmentation tasks. AdvChain augments data with dynamic data augmentation, generating randomly chained photo-metric and geometric transformations to resemble realistic yet challenging imaging variations to expand training data. By jointly optimizing the data augmentation model and a segmentation network during training, challenging examples are generated to enhance network generalizability for the downstream task. The proposed adversarial data augmentation does not rely on generative networks and can be used as a plug-in module in general segmentation networks. It is computationally efficient and applicable for both low-shot supervised and semi-supervised learning. We analyze and evaluate the method on two MR image segmentation tasks: cardiac segmentation and prostate segmentation with limited labeled data. Results show that the proposed approach can alleviate the need for labeled data while improving model generalization ability, indicating its practical value in medical imaging applications.

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SAM-MPA: Applying SAM to Few-shot Medical Image Segmentation using Mask Propagation and Auto-prompting

Medical image segmentation often faces the challenge of prohibitively expensive annotation costs. While few-shot learning offers a promising solution to alleviate this burden, conventional approaches still rely heavily on pre-training with large volumes of labeled data from known categories. To address this issue, we propose leveraging the Segment Anything Model (SAM), pre-trained on over 1 billion masks, thus circumventing the need for extensive domain-specific annotated data. In light of this, we developed SAM-MPA, an innovative SAM-based framework for few-shot medical image segmentation using Mask Propagation-based Auto-prompting. Initially, we employ k-centroid clustering to select the most representative examples for labelling to construct the support set. These annotated examples are registered to other images yielding deformation fields that facilitate the propagation of the mask knowledge to obtain coarse masks across the dataset. Subsequently, we automatically generate visual prompts based on the region and boundary expansion of the coarse mask, including points, box and a coarse mask. Finally, we can obtain the segmentation predictions by inputting these prompts into SAM and refine the results by post refinement module. We validate the performance of the proposed framework through extensive experiments conducted on two medical image datasets with different modalities. Our method achieves Dices of 74.53%, 94.36% on Breast US, Chest X-ray, respectively. Experimental results substantiate that SAM-MPA yields high-accuracy segmentations within 10 labeled examples, outperforming other state-of-the-art few-shot auto-segmentation methods. Our method enables the customization of SAM for any medical image dataset with a small number of labeled examples.

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Clean Label Disentangling for Medical Image Segmentation with Noisy Labels

Current methods focusing on medical image segmentation suffer from incorrect annotations, which is known as the noisy label issue. Most medical image segmentation with noisy labels methods utilize either noise transition matrix, noise-robust loss functions or pseudo-labeling methods, while none of the current research focuses on clean label disentanglement. We argue that the main reason is that the severe class-imbalanced issue will lead to the inaccuracy of the selected ``clean'' labels, thus influencing the robustness of the model against the noises. In this work, we come up with a simple but efficient class-balanced sampling strategy to tackle the class-imbalanced problem, which enables our newly proposed clean label disentangling framework to successfully select clean labels from the given label sets and encourages the model to learn from the correct annotations. However, such a method will filter out too many annotations which may also contain useful information. Therefore, we further extend our clean label disentangling framework to a new noisy feature-aided clean label disentangling framework, which takes the full annotations into utilization to learn more semantics. Extensive experiments have validated the effectiveness of our methods, where our methods achieve new state-of-the-art performance. Our code is available at https://github.com/xiaoyao3302/2BDenoise.

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Informing selection of performance metrics for medical image segmentation evaluation using configurable synthetic errors

Machine learning-based segmentation in medical imaging is widely used in clinical applications from diagnostics to radiotherapy treatment planning. Segmented medical images with ground truth are useful for investigating the properties of different segmentation performance metrics to inform metric selection. Regular geometrical shapes are often used to synthesize segmentation errors and illustrate properties of performance metrics, but they lack the complexity of anatomical variations in real images. In this study, we present a tool to emulate segmentations by adjusting the reference (truth) masks of anatomical objects extracted from real medical images. Our tool is designed to modify the defined truth contours and emulate different types of segmentation errors with a set of user-configurable parameters. We defined the ground truth objects from 230 patient images in the Glioma Image Segmentation for Radiotherapy (GLIS-RT) database. For each object, we used our segmentation synthesis tool to synthesize 10 versions of segmentation (i.e., 10 simulated segmentors or algorithms), where each version has a pre-defined combination of segmentation errors. We then applied 20 performance metrics to evaluate all synthetic segmentations. We demonstrated the properties of these metrics, including their ability to capture specific types of segmentation errors. By analyzing the intrinsic properties of these metrics and categorizing the segmentation errors, we are working toward the goal of developing a decision-tree tool for assisting in the selection of segmentation performance metrics.

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Temporally-Extended Prompts Optimization for SAM in Interactive Medical Image Segmentation

The Segmentation Anything Model (SAM) has recently emerged as a foundation model for addressing image segmentation. Owing to the intrinsic complexity of medical images and the high annotation cost, the medical image segmentation (MIS) community has been encouraged to investigate SAM's zero-shot capabilities to facilitate automatic annotation. Inspired by the extraordinary accomplishments of interactive medical image segmentation (IMIS) paradigm, this paper focuses on assessing the potential of SAM's zero-shot capabilities within the IMIS paradigm to amplify its benefits in the MIS domain. Regrettably, we observe that SAM's vulnerability to prompt forms (e.g., points, bounding boxes) becomes notably pronounced in IMIS. This leads us to develop a framework that adaptively offers suitable prompt forms for human experts. We refer to the framework above as temporally-extended prompts optimization (TEPO) and model it as a Markov decision process, solvable through reinforcement learning. Numerical experiments on the standardized benchmark BraTS2020 demonstrate that the learned TEPO agent can further enhance SAM's zero-shot capability in the MIS context.

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Research on Improved U-net Based Remote Sensing Image Segmentation Algorithm

In recent years, although U-Net network has made significant progress in the field of image segmentation, it still faces performance bottlenecks in remote sensing image segmentation. In this paper, we innovatively propose to introduce SimAM and CBAM attention mechanism in U-Net, and the experimental results show that after adding SimAM and CBAM modules alone, the model improves 17.41% and 12.23% in MIoU, and the Mpa and Accuracy are also significantly improved. And after fusing the two,the model performance jumps up to 19.11% in MIoU, and the Mpa and Accuracy are also improved by 16.38% and 14.8% respectively, showing excellent segmentation accuracy and visual effect with strong generalization ability and robustness. This study opens up a new path for remote sensing image segmentation technology and has important reference value for algorithm selection and improvement.

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Fed-ADApt: Federated Anytime Depth Adaptation for Resource-Aware Medical Image Segmentation

Federated learning (FL) enables collaborative training of medical image segmentation models without sharing raw patient data, yet existing approaches assume a homogeneous compute budget across institutions, limiting participation of low-resource sites. We propose Fed-ADApt, a depth-adaptive federated framework for UNet-based segmentation that jointly addresses low-compute training and inference. Fed-ADApt integrates multi-depth supervision with hierarchical depth-wise aggregation, allowing each site to train according to its local compute budget while contributing to a global model that supports dynamic depth selection at deployment. We evaluated Fed-ADApt on multi-site 2D retinal fundus disc segmentation and 3D brain tumor segmentation. Across both tasks, federated collaboration substantially improves robustness under domain shift. Fed-ADApt matched the full-resource FedAvg performance in 3D and achieved competitive 2D performance with a 4.7% average Dice reduction, while reducing average inference cost by 19.5% in 3D and 34.5% in 2D and substantially reducing training cost by 98% at the most constrained sites. Importantly, Fed-ADApt enables low-resource institutions that cannot train full-capacity models to participate in federations while maintaining competitive global performance under a favorable accuracy to efficiency trade-off. By considering training and inference compute budgets, Fed-ADApt provides a practical and equitable solution for federated medical image segmentation across heterogeneous clinical and edge-enabled imaging environments.

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A Formal Evaluation of PSNR as Quality Measurement Parameter for Image Segmentation Algorithms

Quality evaluation of image segmentation algorithms are still subject of debate and research. Currently, there is no generic metric that could be applied to any algorithm reliably. This article contains an evaluation for the PSRN (Peak Signal-To-Noise Ratio) as a metric which has been used to evaluate threshold level selection as well as the number of thresholds in the case of multi-level segmentation. The results obtained in this study suggest that the PSNR is not an adequate quality measurement for segmentation algorithms.

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A Restricted-Domain Dual Formulation for Two-Phase Image Segmentation

In two-phase image segmentation, convex relaxation has allowed global minimisers to be computed for a variety of data fitting terms. Many efficient approaches exist to compute a solution quickly. However, we consider whether the nature of the data fitting in this formulation allows for reasonable assumptions to be made about the solution that can improve the computational performance further. In particular, we employ a well known dual formulation of this problem and solve the corresponding equations in a restricted domain. We present experimental results that explore the dependence of the solution on this restriction and quantify imrovements in the computational performance. This approach can be extended to analogous methods simply and could provide an efficient alternative for problems of this type.

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3D Deep Affine-Invariant Shape Learning for Brain MR Image Segmentation

Recent advancements in medical image segmentation techniques have achieved compelling results. However, most of the widely used approaches do not take into account any prior knowledge about the shape of the biomedical structures being segmented. More recently, some works have presented approaches to incorporate shape information. However, many of them are indeed introducing more parameters to the segmentation network to learn the general features, which any segmentation network is able learn, instead of specifically shape features. In this paper, we present a novel approach that seamlessly integrates the shape information into the segmentation network. Experiments on human brain MRI segmentation demonstrate that our approach can achieve a lower Hausdorff distance and higher Dice coefficient than the state-of-the-art approaches.

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Post Training Uncertainty Calibration of Deep Networks For Medical Image Segmentation

Neural networks for automated image segmentation are typically trained to achieve maximum accuracy, while less attention has been given to the calibration of their confidence scores. However, well-calibrated confidence scores provide valuable information towards the user. We investigate several post hoc calibration methods that are straightforward to implement, some of which are novel. They are compared to Monte Carlo (MC) dropout. They are applied to neural networks trained with cross-entropy (CE) and soft Dice (SD) losses on BraTS 2018 and ISLES 2018. Surprisingly, models trained on SD loss are not necessarily less calibrated than those trained on CE loss. In all cases, at least one post hoc method improves the calibration. There is limited consistency across the results, so we can't conclude on one method being superior. In all cases, post hoc calibration is competitive with MC dropout. Although average calibration improves compared to the base model, subject-level variance of the calibration remains similar.

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