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arXiv · 2110.08457

Metagenome assembly of high-fidelity long reads with hifiasm-meta

Xiaowen Feng·Haoyu Cheng·Daniel Portik·Heng Li
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Abstract

Current metagenome assemblers developed for short sequence reads or noisy long readswere not optimized for accurate long reads. Here we describe hifiasm-meta, a new metagenome assembler that exploits the high accuracy of recent data. Evaluated on seven empirical datasets, hifiasm-meta reconstructed tens to hundreds of complete circular bacterial genomes per dataset, consistently outperforming other metagenome assemblers.

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Xiaowen Feng, Haoyu Cheng, Daniel Portik, Heng Li. 2021-10-16. Metagenome assembly of high-fidelity long reads with hifiasm-meta. https://arxiv.org/abs/2110.08457

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