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arXiv · 2402.02326

Watt-level all polarization-maintaining femtosecond fiber laser source at 1100 nm for multicolor two-photon fluorescence excitation of fluorescent proteins

Junpeng Wen·Christian Pilger·Wenlong Wang·Raghu Erapaneedi·Hao Xiu·Yiheng Fan·Xu Hu·Thomas Huser·Friedemann Kiefer·Xiaoming Wei·Zhongmin Yang
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Abstract

We demonstrate a compact watt-level all polarization-maintaining (PM) femtosecond fiber laser source at 1100 nm. The fiber laser source is seeded by an all PM fiber mode-locked laser employing a nonlinear amplifying loop mirror. The seed laser can generate stable pulses at a fundamental repetition rate of 40.71 MHz with a signal-to-noise rate of >100 dB and an integrated relative intensity noise of only ~0.061%. After two-stage external amplification and pulse compression, an output power of ~1.47 W (corresponding to a pulse energy of ~36.1 nJ) and a pulse duration of ~251 fs are obtained. The 1100 nm femtosecond fiber laser is then employed as the excitation light source for multicolor multi-photon fluorescence microscopy of Chinese hamster ovary (CHO) cells stably expressing red fluorescent proteins.

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Junpeng Wen, Christian Pilger, Wenlong Wang, Raghu Erapaneedi, Hao Xiu, Yiheng Fan, Xu Hu, Thomas Huser, Friedemann Kiefer, Xiaoming Wei, Zhongmin Yang. 2024-02-04. Watt-level all polarization-maintaining femtosecond fiber laser source at 1100 nm for multicolor two-photon fluorescence excitation of fluorescent proteins. https://arxiv.org/abs/2402.02326

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