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arXiv · 2501.15464

TractoGPT: A GPT architecture for White Matter Segmentation

Anoushkrit Goel·Simroop Singh·Ankita Joshi·Ranjeet Ranjan Jha·Chirag Ahuja·Aditya Nigam·Arnav Bhavsar
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Abstract

White matter bundle segmentation is crucial for studying brain structural connectivity, neurosurgical planning, and neurological disorders. White Matter Segmentation remains challenging due to structural similarity in streamlines, subject variability, symmetry in 2 hemispheres, etc. To address these challenges, we propose TractoGPT, a GPT-based architecture trained on streamline, cluster, and fusion data representations separately. TractoGPT is a fully-automatic method that generalizes across datasets and retains shape information of the white matter bundles. Experiments also show that TractoGPT outperforms state-of-the-art methods on average DICE, Overlap and Overreach scores. We use TractoInferno and 105HCP datasets and validate generalization across dataset.

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Anoushkrit Goel, Simroop Singh, Ankita Joshi, Ranjeet Ranjan Jha, Chirag Ahuja, Aditya Nigam, Arnav Bhavsar. 2025-01-26. TractoGPT: A GPT architecture for White Matter Segmentation. https://arxiv.org/abs/2501.15464

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