Search arXivSearch

arXiv · 2502.04345

Jingfang: An LLM-Based Multi-Agent System for Precise Medical Consultation and Syndrome Differentiation in Traditional Chinese Medicine

Abstract

The practice of Traditional Chinese Medicine (TCM) requires profound expertise and extensive clinical experience. While Large Language Models (LLMs) offer significant potential in this domain, current TCM-oriented LLMs suffer two critical limitations: (1) a rigid consultation framework that fails to conduct comprehensive and patient-tailored interactions, often resulting in diagnostic inaccuracies; and (2) treatment recommendations generated without rigorous syndrome differentiation, which deviates from the core diagnostic and therapeutic principles of TCM. To address these issues, we develop \textbf{JingFang (JF)}, an advanced LLM-based multi-agent system for TCM that facilitates the implementation of AI-assisted TCM diagnosis and treatment. JF integrates various TCM Specialist Agents in accordance with authentic diagnostic and therapeutic scenarios of TCM, enabling personalized medical consultations, accurate syndrome differentiation and treatment recommendations. A \textbf{Multi-Agent Collaborative Consultation Mechanism (MACCM)} for TCM is constructed, where multiple Agents collaborate to emulate real-world TCM diagnostic workflows, enhancing the diagnostic ability of base LLMs to provide accurate and patient-tailored medical consultation. Moreover, we introduce a dedicated \textbf{Syndrome Differentiation Agent} fine-tuned on a preprocessed dataset, along with a designed \textbf{Dual-Stage Recovery Scheme (DSRS)} within the Treatment Agent, which together substantially improve the model's accuracy of syndrome differentiation and treatment. Comprehensive evaluations and experiments demonstrate JF's superior performance in medical consultation, and also show improvements of at least 124% and 21.1% in the precision of syndrome differentiation compared to existing TCM models and State of the Art (SOTA) LLMs, respectively.

Explore related subjects

Keep this discovery

Explore connections, maps & timelines

BibTeXRIS

Yehan Yang, Tianhao Ma, Ruotai Li, Xinhan Zheng, Guodong Shan. 2026-01-20. Jingfang: An LLM-Based Multi-Agent System for Precise Medical Consultation and Syndrome Differentiation in Traditional Chinese Medicine. https://arxiv.org/abs/2502.04345

Cite the original work for its findings. Save a collection to share your selection of sources.

KEEP EXPLORING

Related papers

SafetyFlow: An Agent-Flow System for Automated LLM Safety Benchmarking

The rapid proliferation of large language models (LLMs) has intensified the requirement for reliable safety evaluation to uncover model vulnerabilities. To this end, numerous LLM safety evaluation benchmarks are proposed. However, existing benchmarks generally rely on labor-intensive manual curation, which causes excessive time and resource consumption. They also exhibit significant redundancy and limited difficulty. To alleviate these problems, we introduce SafetyFlow, the first agent-flow system designed to automate the construction of LLM safety benchmarks. SafetyFlow can automatically build a comprehensive safety benchmark in only four days without any human intervention by orchestrating seven specialized agents, significantly reducing time and resource cost. Equipped with versatile tools, the agents of SafetyFlow ensure process and cost controllability while integrating human expertise into the automatic pipeline. The final constructed dataset, SafetyFlowBench, contains 23,446 queries with low redundancy and strong discriminative power. Our contribution includes the first fully automated benchmarking pipeline and a comprehensive safety benchmark. We evaluate the safety of 49 advanced LLMs on our dataset and conduct extensive experiments to validate our efficacy and efficiency.

cs.CL

Geometric Uncertainty for Detecting and Correcting Hallucinations in LLMs

Large language models are known to hallucinate, generating linguistically plausible but incorrect answers to questions. Uncertainty quantification has been proposed as a strategy to detect such behaviour, but existing methods lack a unified framework to assess reliability at both the prompt and answer level. We introduce a geometric framework which quantifies language model uncertainty at both levels by explicitly modelling a prompt-conditioned semantic distribution in answer embedding space. Our approach is black-box and sampling-based; we generate multiple answers per prompt, and use archetypal analysis to estimate a geometric support for the answer distribution. At the prompt level, we approximate the distribution entropy to quantify uncertainty; for each individual answer, we then use notions of atypicality to assess its reliability relative to the batch. We employ our framework to not only detect hallucinations but correct them, by selecting the batch example deemed most reliable. Experiments show that our framework performs comparably to or better than prior methods on short form question-answering datasets, and achieves superior results on medical datasets where hallucinations carry particularly critical risks. Beyond pure performance, we suggest the theoretical grounding of our work provides support for semantic distributions as useful objects of study for language model uncertainty.

cs.CL

Calibrated Confidence Expression for Radiology Report Generation

Safe deployment of Large Vision-Language Models (LVLMs) in radiology report generation requires not only accurate predictions but also clinically interpretable indicators of when outputs should be thoroughly reviewed, enabling selective radiologist verification and reducing the risk of hallucinated findings influencing clinical decisions. One intuitive approach to this is verbalized confidence, where the model explicitly states its certainty. However, current state-of-the-art language models are often overconfident, and research on calibration in multimodal settings such as radiology report generation is limited. To address this gap, we introduce ConRad (Confidence Calibration for Radiology Reports), a reinforcement learning framework for fine-tuning medical LVLMs to produce calibrated verbalized confidence estimates alongside radiology reports. We study two settings: a single report-level confidence score and a sentence-level variant assigning a confidence to each claim. Both are trained using the GRPO algorithm with reward functions based on the logarithmic scoring rule, which incentivizes truthful self-assessment by penalizing miscalibration and guarantees optimal calibration under reward maximization. Experimentally, ConRad substantially improves calibration and outperforms competing methods. In a clinical evaluation we show that ConRad's report level scores are well aligned with clinicians' judgment. By highlighting full reports or low-confidence statements for targeted review, ConRad can support safer clinical integration of AI-assistance for report generation.

cs.CL