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arXiv · 2504.06921

Leveraging Anatomical Priors for Automated Pancreas Segmentation on Abdominal CT

Anisa V. Prasad·Tejas Sudharshan Mathai·Pritam Mukherjee·Jianfei Liu·Ronald M. Summers
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Abstract

An accurate segmentation of the pancreas on CT is crucial to identify pancreatic pathologies and extract imaging-based biomarkers. However, prior research on pancreas segmentation has primarily focused on modifying the segmentation model architecture or utilizing pre- and post-processing techniques. In this article, we investigate the utility of anatomical priors to enhance the segmentation performance of the pancreas. Two 3D full-resolution nnU-Net models were trained, one with 8 refined labels from the public PANORAMA dataset, and another that combined them with labels derived from the public TotalSegmentator (TS) tool. The addition of anatomical priors resulted in a 6\% increase in Dice score ($p < .001$) and a 36.5 mm decrease in Hausdorff distance for pancreas segmentation ($p < .001$). Moreover, the pancreas was always detected when anatomy priors were used, whereas there were 8 instances of failed detections without their use. The use of anatomy priors shows promise for pancreas segmentation and subsequent derivation of imaging biomarkers.

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Anisa V. Prasad, Tejas Sudharshan Mathai, Pritam Mukherjee, Jianfei Liu, Ronald M. Summers. 2025-04-09. Leveraging Anatomical Priors for Automated Pancreas Segmentation on Abdominal CT. https://arxiv.org/abs/2504.06921

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