Search arXivSearch

arXiv · 2508.18217

Lost Data in Electron Microscopy

Abstract

The goal of this study is to estimate the amount of lost data in electron microscopy and to analyze the extent to which experimentally acquired images are utilized in peer-reviewed scientific publications. Analysis of the number of images taken on electron microscopes at a core user facility and the number of images subsequently included in peer-reviewed scientific journals revealed low efficiency of data utilization. Up to around 90% of electron microscopy data generated during routine instrument operation remain unused. Of the more than 150 000 electron microscopy images evaluated in this study, only approximately 3 500 (just over 2%) were made available in publications. For the analyzed dataset, the amount of lost data in electron microscopy can be estimated as >90% (in terms of data being recorded but not being published in peer-reviewed literature). On the one hand, these results highlight a shortcoming in the optimal use of microscopy images; on the other hand, they indicate the existence of a large pool of electron microscopy data that can facilitate research in data science and the development of AI-based projects. The considerations important to unlock the potential of lost data are discussed in the present article.

Explore related subjects

Keep this discovery

Explore connections, maps & timelines

BibTeXRIS

Nina M. Ivanova, Alexey S. Kashin, Valentine P. Ananikov. 2025-09-17. Lost Data in Electron Microscopy. https://doi.org/10.3390/chemistry7050160

Cite the original work for its findings. Save a collection to share your selection of sources.

KEEP EXPLORING

Related papers

Towards Effective Orchestration of AI x DB Workloads

AI-driven analytics are increasingly crucial to data-centric decision-making. Executing relational and AI operators in separate runtimes prevents the database optimizer and runtime from coordinating operator ordering, model placement, batching, and state reuse. Integrating AI operators into database engines enables such coordination but raises challenges in jointly optimizing query processing and model execution, scheduling under resource contention, and reusing relational intermediates and AI artifacts. This paper formalizes AIxDB workloads as iterative, concurrent, and shareable executions that interleave relational and AI operators. We then advocate database-native orchestration as a paradigm for redesigning database engines for these workloads and distill two design principles: holistic AIxDB co-optimization and unified AIxDB cache management. We present NeurEngine as a proof-of-concept prototype and report preliminary results illustrating the performance benefits of database-native orchestration

cs.DB

Benchmarking Text-to-SQL under Role-Based Access Control

Given a database S and a natural language question Q, text-to-SQL systems aim to generate an SQL query that correctly answers Q when executed against S. Currently, popular text-to-SQL benchmarks mostly assume unrestricted access to S; in practice, however, user access is often restricted, e.g., through role-based access control (RBAC) policies. This leads to a potential disconnect between benchmarking results and real-world performance: an LLM with high benchmark scores might perform poorly in an access-controlled environment, by frequently violating RBAC, or rejecting a query q that could be answered with only permitted data in S. Motivated by this, we present a comprehensive text-to-SQL benchmarking framework with realistic RBAC constraints, which features an LLM-assisted workflow that augments existing text-to-SQL benchmarks with plausible user roles and access policies. To do so, we formulate the problem of role synthesis as a structured reasoning process over the database schema, in which the LLM first infers the application context from the schema, and then derives role responsibilities and access scopes consistent with this context. This process is audited by human-in-the-loop quality control, in which domain experts perform metric-guided screening on the generated roles. Besides the augmented dataset, the proposed framework also contains evaluation metrics that identify RBAC-specific failure modes, and disentangle SQL utility from access-control compliance. We apply the proposed framework to several widely-used benchmarks, and conduct a systematic empirical study of state-of-the-art text-to-SQL systems. The results show that many solutions (especially open-weight LLMs) with high benchmarking scores under an unrestricted setting suffer sharp performance degradation once access constraints are in place, due to frequent RBAC violations.

cs.DB

A Functional Pilot for Certified Freshness-Aware Semantic--Spatial Range Retrieval

Geographic applications need every object inside a radius that satisfies a semantic threshold, yet embedding indexes return approximate top-ranked lists and may omit qualifying records silently. We present FRESH-GEORANGE, a semantic- spatial range design that separates source-watermark freshness from optional record age. Geographic cells and semantic mi- croblocks provide admissible pruning bounds; a graph proposes verification order but supplies no correctness evidence. Exact mode scans every nonprunable block and the delta overlay. Certified mode may stop early and reports a deterministic query- specific recall lower bound from verified answers and unresolved records. A reproducible CPU pilot uses 2,500 real OpenFlights airport records, a 2,000-record base, and 740 simulated insert, delete, and text-revision events; it evaluates 180 unique queries over five seeds. Exact mode achieved 100.00% set recall on every query. The 95-percent mode achieved 99.91% empirical mean recall with a 99.41% reported mean certificate and no observed bound violation. However, its 7.24 ms median latency was 5.85 times the 1.24 ms spatial-first exact baseline, and full-history delta replay became slower than rebuilding at larger batches. The prototype therefore validates the completeness mechanism, not performance superiority or production freshness. Submission- scale evaluation requires real map diffs, official recent baselines, and truly incremental versioned maintenance.

cs.DB