Agentic Discovery: Closing the Loop with Cooperative Agents

J. Gregory Pauloski; Kyle Chard; Ian T. Foster

doi:10.1109/mc.2025.3575029

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arXiv · 2510.13081

Agentic Discovery: Closing the Loop with Cooperative Agents

J. Gregory Pauloski·Kyle Chard·Ian T. Foster

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Abstract

As data-driven methods, artificial intelligence (AI), and automated workflows accelerate scientific tasks, we see the rate of discovery increasingly limited by human decision-making tasks such as setting objectives, generating hypotheses, and designing experiments. We postulate that cooperative agents are needed to augment the role of humans and enable autonomous discovery. Realizing such agents will require progress in both AI and infrastructure.

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J. Gregory Pauloski, Kyle Chard, Ian T. Foster. 2025-10-15. Agentic Discovery: Closing the Loop with Cooperative Agents. https://doi.org/10.1109/mc.2025.3575029

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