Search arXiv⌕ Search

arXiv · 2610.15714

MedHarnessBench: A Unified Benchmark for Healthcare Agent Evaluation

Abstract

Healthcare agents must transform longitudinal clinical evidence into reliable actions through heterogeneous tools and stateful workflows, conditions under which model-centric systems may lose context, misuse tools, fail to verify consequential transitions, or cross authorization boundaries. Existing medical-agent benchmarks primarily emphasize terminal task outcomes, making it difficult to determine whether execution failures arise from the agent model, the runtime harness, or their interaction. We present the Medical Harness Protocol, an outcome-preserving framework that independently evaluates seven healthcare-specific process dimensions: Care Action Fulfillment, Clinical Resource Competence, Patient-Evidence Alignment, Clinical Workflow Continuity, Clinical Auditability, Closed-Loop Verification, and Clinical Conduct Boundaries. A normalized intervention trace further tracks whether runtime support is available, activated, delivered, adopted by the agent, and propagated into subsequent behavior. We instantiate the protocol as MedHarnessBench, comprising 342 executable tasks across FHIR/EHR operations, healthcare-administration interfaces, and multimodal clinical tools. Across more than 16,000 controlled task executions, MedHarness yields broad improvements in terminal task success, intermediate subtask completion, and healthcare-specific process quality. We further evaluate MedHarness against multiple general-purpose harnesses and use controlled single-fault perturbations to verify the sensitivity and discrimination of the seven-dimensional evaluation. These results demonstrate that healthcare-specific runtime support can substantially improve both task completion and execution quality, while revealing failures that terminal outcomes alone cannot capture. Code and resources are available at https://github.com/Tomry1114/Awesome-Agent-Harness-for-Healthcare.

Explore related subjects

Keep this discovery

Explore connections, maps & timelines

BibTeXRIS

Rui Tang, Hongqiu Wang. 2026-10-11. MedHarnessBench: A Unified Benchmark for Healthcare Agent Evaluation. https://arxiv.org/abs/2610.15714

Cite the original work for its findings. Save a collection to share your selection of sources.

KEEP EXPLORING

Related papers

Agent-Environment Alignment via Automated Interface Generation

Large language model (LLM) agents have shown impressive reasoning capabilities in interactive decision-making tasks. These agents interact with environment through intermediate interfaces, such as predefined action spaces and interaction rules, which mediate the perception and action. However, mismatches often happen between the internal expectations of the agent regarding the influence of its issued actions and the actual state transitions in the environment, a phenomenon referred to as \textbf{agent-environment misalignment}. While prior work has invested substantially in improving agent strategies and environment design, the critical role of the interface still remains underexplored. In this work, we empirically demonstrate that agent-environment misalignment poses a significant bottleneck to agent performance. To mitigate this issue, we propose \textbf{ALIGN}, an \underline{A}uto-A\underline{l}igned \underline{I}nterface \underline{G}e\underline{n}eration framework that alleviates the misalignment by enriching the interface. Specifically, the ALIGN-generated interface enhances both the static information of the environment and the step-wise observations returned to the agent. Implemented as a lightweight wrapper, this interface achieves the alignment without modifying either the agent logic or the environment code. Experiments across multiple domains including embodied tasks, web navigation and tool-use, show consistent performance improvements, with up to a 45.67\% success rate improvement observed in ALFWorld. Meanwhile, ALIGN-generated interface can generalize across different agent architectures and LLM backbones without interface regeneration. Code and experimental results are available at https://github.com/THUNLP-MT/ALIGN.

cs.AI↗

ROI-Reasoning: Rational Optimization for Inference via Pre-Computation Meta-Cognition

Large language models (LLMs) can achieve strong reasoning performance with sufficient computation, but they do not inherently know how much computation a task requires. We study budgeted inference-time reasoning for multiple problems under a strict global token constraint and formulate it as an Ordered Stochastic Multiple-Choice Knapsack Problem (OS-MCKP). This perspective highlights a meta-cognitive requirement---anticipating problem difficulty and allocating computation strategically. We propose ROI-Reasoning, a two-stage framework that endows LLMs with intrinsic, budget-aware rationality. First, Meta-Cognitive Fine-Tuning teaches models to predict reasoning cost levels and decide whether a problem is worth attempting before generation. Next, Rationality-Aware Reinforcement Learning optimizes sequential decision making under a hard token budget, allowing models to learn long-horizon allocation strategies. Experiments across mathematical reasoning, multiple-choice question answering, and code generation show that ROI-Reasoning improves scores and generally reduces reference-order regret under tight budgets, with up to a \textbf{417\%} relative score improvement over the strongest same-backbone baseline in mathematics.

cs.AI↗

ReCreate: Reasoning and Creating Domain Agents Driven by Experience

Large Language Model (LLM) agents are reshaping the industrial landscape. However, most practical agents still rely on human-designed scaffolds, making their creation and adaptation across diverse domains labor-intensive. This situation poses a central question: can we automatically create and evolve domain agents through interaction experience in real-world environments? While recent approaches have sought to automate agent creation, several treat scaffold optimization as a black-box procedure guided primarily by final performance metrics. Such strategies overlook critical evidence explaining why an agent succeeds or fails and often incur high computational costs. To address these limitations, we propose ReCreate, an experience-driven framework for creating and evolving specialized domain agents. ReCreate systematically leverages agent interaction histories to identify the causes of success and failure and guide targeted scaffold updates. Specifically, we introduce an agent-as-optimizer paradigm in which an optimizer agent actively inspects execution experience and iteratively refines the task agent's scaffold through three key components: (i) an experience storage and retrieval mechanism for on-demand evidence inspection; (ii) a reasoning-creating synergy pipeline that translates execution evidence into updates to prompts, workflows, tools, and memory; and (iii) hierarchical updates that consolidate instance-level refinements into reusable domain-level improvements. Experiments across thirteen evaluation settings spanning four domains show that ReCreate consistently outperforms human-designed agents and existing automated agent generation and self-evolving baselines, even when evolving from minimal seed scaffolds.

cs.AI↗