arXiv subjects

Bing Yu

Publications and source records attributed to Bing Yu.

At least 19 recordsLinked to original sources

arXiv2026

Clinical Feasibility of Low-Magnification Fluorescence Imaging for Breast Cancer Margin Detection Using Texture Analysis and Deep Learning

High-resolution images of unprocessed surgical breast tissue can be obtained using microscopy with ultraviolet surface excitation (MUSE). This technique is considered a promising method for checking surgical margins during breast cancer surgery. In this study, MUSE images at 4x and 10x magnifications were compared using patch-level classification methods. Texture analysis (TA) based on local binary patterns (LBP) and deep learning (DL) with a base Vision Transformer (ViT) model were used. Both methods achieved similar performance at both magnifications. Using DL method, both 4x and 10x magnifications achieved 96.30% sensitivity, 100% specificity and 98.18% accuracy. Using TA method, 4x achieved better specificity (100% vs 93.33%) and 10x yielded higher sensitivity (100% vs 93.33%), but both had the same accuracy (96.67%). No clear improvement in performance was observed with 10x magnification. These results show that 4x imaging achieves the same diagnostic accuracy as 10x imaging. At the same time, 4x offers a larger field of view and faster image capture. Therefore, lower magnification can be effectively used in MUSE systems for accurate and efficient intraoperative margin assessment.

cs.CV↗

arXiv2026

Nonlocal advantage of quantum imaginarity in Schwarzchild spacetime

Black hole spacetimes provide a natural setting for quantum systems in curved spacetime, where effects such as Hawking radiation arise from event horizons. In this work, we investigate the impact of the Hawking effect on quantum imaginarity in Schwarzschild spacetime, focusing on nonlocal advantage of quantum imaginarity (NAQI) and assisted imaginarity distillation. For NAQI, it is significantly affected by Hawking radiation, exhibiting a pronounced difference between physically accessible and inaccessible regions. It is suppressed in the physically accessible region with increasing Hawking temperature and may vanish, while remaining absent in the physically inaccessible region across the parameter regime. For assisted imaginarity distillation, the Hawking effect modifies the assisted fidelity in a state-dependent manner. In the physically accessible region, the fidelity generally decreases with increasing temperature, indicating reduced distillation capability, whereas the physically inaccessible region exhibits the opposite monotonic trend, indicating enhanced distillation capability. These results highlight distinct operational behaviors of physically accessible and inaccessible regions under relativistic effects, providing insight into quantum imaginarity in curved spacetime.

quant-ph↗

arXiv2026

Self-learned representation-guided latent diffusion model for breast cancer classification in deep ultraviolet whole surface images

Breast-Conserving Surgery (BCS) requires precise intraoperative margin assessment to preserve healthy tissue. Deep Ultraviolet Fluorescence Scanning Microscopy (DUV-FSM) offers rapid, high-resolution surface imaging for this purpose; however, the scarcity of annotated DUV data hinders the training of robust deep learning models. To address this, we propose an Self-Supervised Learning (SSL)-guided Latent Diffusion Model (LDM) to generate high-quality synthetic training patches. By guiding the LDM with embeddings from a fine-tuned DINO teacher, we inject rich semantic details of cellular structures into the synthetic data. We combine real and synthetic patches to fine-tune a Vision Transformer (ViT), utilizing patch prediction aggregation for WSI-level classification. Experiments using 5-fold cross-validation demonstrate that our method achieves 96.47 % accuracy and reduces the FID score to 45.72, significantly outperforming class-conditioned baselines.

cs.CV↗

arXiv2026

Anatomy Aware Cascade Network: Bridging Epistemic Uncertainty and Geometric Manifold for 3D Tooth Segmentation

Accurate three-dimensional (3D) tooth segmentation from Cone-Beam Computed Tomography (CBCT) is a prerequisite for digital dental workflows. However, achieving high-fidelity segmentation remains challenging due to adhesion artifacts in naturally occluded scans, which are caused by low contrast and indistinct inter-arch boundaries. To address these limitations, we propose the Anatomy Aware Cascade Network (AACNet), a coarse-to-fine framework designed to resolve boundary ambiguity while maintaining global structural consistency. Specifically, we introduce two mechanisms: the Ambiguity Gated Boundary Refiner (AGBR) and the Signed Distance Map guided Anatomical Attention (SDMAA). The AGBR employs an entropy based gating mechanism to perform targeted feature rectification in high uncertainty transition zones. Meanwhile, the SDMAA integrates implicit geometric constraints via signed distance map to enforce topological consistency, preventing the loss of spatial details associated with standard pooling. Experimental results on a dataset of 125 CBCT volumes demonstrate that AACNet achieves a Dice Similarity Coefficient of 90.17 \% and a 95\% Hausdorff Distance of 3.63 mm, significantly outperforming state-of-the-art methods. Furthermore, the model exhibits strong generalization on an external dataset with an HD95 of 2.19 mm, validating its reliability for downstream clinical applications such as surgical planning. Code for AACNet is available at https://github.com/shiliu0114/AACNet.

cs.CV↗

arXiv2025

Reusability of Quantum Catalysts

Quantum catalysts enable transformations that otherwise would be forbidden, offering a pathway to surpass conventional limits in quantum information processing. Among them, embezzling catalysts stand out for achieving near-perfect performance while tolerating only minimal disturbance, bridging the gap between ideal and practical catalysis. Yet, this superior capability comes at a cost: Each use slightly degrades the catalyst, leading to an inevitable accumulation of imperfection. This gradual decay defines their most distinctive property -- reusability -- which, despite its fundamental importance, remains largely unexplored. Here, we establish a quantitative framework to characterize the operational lifetime of embezzling catalysts, focusing on their role in entanglement distillation and extending the analysis to quantum teleportation. We show that the catalytic advantage inevitably diminishes with repeated use, deriving bounds on the maximum effective reuse rounds for a desired performance gain. Our results uncover the finite reusability of catalysts in quantum processes and point toward sustainable strategies for quantum communication.

quant-ph↗

arXiv2025

SeamlessFlow: A Trainer Agent Isolation RL Framework Achieving Bubble-Free Pipelines via Tag Scheduling

We introduce SeamlessFlow, a server based reinforcement learning (RL) framework that addresses two core challenges in industrial scale RL: (1) decoupling RL training from the complex execution flow of agents; (2) maximizing GPU utilization with minimal idle time while preserving the stability and scalability required for large-scale deployments. First, SeamlessFlow introduces a data plane that decouples the RL trainer from diverse, complex agent implementations while sustaining high throughput. A central trajectory manager maintains complete interaction histories and supports partial rollout, allowing rollout to pause for weight updates and resume seamlessly, keeping agents unaware of service interruptions. Second, we propose a tag driven scheduling paradigm that abstracts hardware into capability tagged resources, unifying colocated and disaggregated architectures. Based on this, SeamlessFlow introduces a spatiotemporal multiplexing pipeline that dynamically reassigns idle training nodes to rollout in a train rollout separated setup, eliminating pipeline bubbles and fully exploiting heterogeneous cluster resources. By combining these innovations, SeamlessFlow delivers both stability and high performance, making it well suited for multi agent, long horizon, and other complex RL tasks.

cs.LG↗

arXiv2025

KAT-V1: Kwai-AutoThink Technical Report

We present Kwaipilot-AutoThink (KAT), an open-source 40B large language model developed to address the overthinking problem in reasoning-intensive tasks, where an automatic thinking training paradigm is proposed to dynamically switch between reasoning and non-reasoning modes based on task complexity. Specifically, first, we construct the dual-regime dataset based on a novel tagging pipeline and a multi-agent synthesis strategy, and then we apply Multi-Token Prediction (MTP)-enhanced knowledge distillation, enabling efficient and fine-grained reasoning transfer with minimal pretraining cost. Besides, we implement a cold-start initialization strategy that introduces mode-selection priors using majority-vote signals and intent-aware prompting. Finally, we propose Step-SRPO, a reinforcement learning algorithm that incorporates intermediate supervision into the GRPO framework, offering structured guidance over both reasoning-mode selection and response accuracy. Extensive experiments across multiple benchmarks demonstrate that KAT consistently matches or even outperforms current state-of-the-art models, including DeepSeek-R1-0528 and Qwen3-235B-A22B, across a wide range of reasoning-intensive tasks while reducing token usage. Notably, KAT outperforms all open-source models and even surpasses o3-mini on the leakage-controlled LiveCodeBench Pro. Beyond academic evaluation, KAT has been successfully deployed in Kwaipilot (i.e., Kuaishou's internal coding assistant), where it improves real-world development workflows with high accuracy, efficiency, and controllable reasoning behaviors. Moreover, we are actively training a 200B Mixture-of-Experts (MoE) model with 40B active parameters, and early results already show significant gains, further demonstrating the scalability of the AutoThink paradigm.

cs.CL↗

arXiv2025

Breast Cancer Classification in Deep Ultraviolet Fluorescence Images Using a Patch-Level Vision Transformer Framework

Breast-conserving surgery (BCS) aims to completely remove malignant lesions while maximizing healthy tissue preservation. Intraoperative margin assessment is essential to achieve a balance between thorough cancer resection and tissue conservation. A deep ultraviolet fluorescence scanning microscope (DUV-FSM) enables rapid acquisition of whole surface images (WSIs) for excised tissue, providing contrast between malignant and normal tissues. However, breast cancer classification with DUV WSIs is challenged by high resolutions and complex histopathological features. This study introduces a DUV WSI classification framework using a patch-level vision transformer (ViT) model, capturing local and global features. Grad-CAM++ saliency weighting highlights relevant spatial regions, enhances result interpretability, and improves diagnostic accuracy for benign and malignant tissue classification. A comprehensive 5-fold cross-validation demonstrates the proposed approach significantly outperforms conventional deep learning methods, achieving a classification accuracy of 98.33%.

eess.IV↗

arXiv2025

SRPO: A Cross-Domain Implementation of Large-Scale Reinforcement Learning on LLM

Recent advances of reasoning models, exemplified by OpenAI's o1 and DeepSeek's R1, highlight the significant potential of Reinforcement Learning (RL) to enhance the reasoning capabilities of Large Language Models (LLMs). However, replicating these advancements across diverse domains remains challenging due to limited methodological transparency. In this work, we present two-Staged history-Resampling Policy Optimization (SRPO), which surpasses the performance of DeepSeek-R1-Zero-32B on the AIME24 and LiveCodeBench benchmarks. SRPO achieves this using the same base model as DeepSeek (i.e. Qwen2.5-32B), using only about 1/10 of the training steps required by DeepSeek-R1-Zero-32B, demonstrating superior efficiency. Building upon Group Relative Policy Optimization (GRPO), we introduce two key methodological innovations: (1) a two-stage cross-domain training paradigm designed to balance the development of mathematical reasoning and coding proficiency, and (2) History Resampling (HR), a technique to address ineffective samples. Our comprehensive experiments validate the effectiveness of our approach, offering valuable insights into scaling LLM reasoning capabilities across diverse tasks.

cs.LG↗

arXiv2025

Physics-informed DeepCT: Sinogram Wavelet Decomposition Meets Masked Diffusion

Diffusion model shows remarkable potential on sparse-view computed tomography (SVCT) reconstruction. However, when a network is trained on a limited sample space, its generalization capability may be constrained, which degrades performance on unfamiliar data. For image generation tasks, this can lead to issues such as blurry details and inconsistencies between regions. To alleviate this problem, we propose a Sinogram-based Wavelet random decomposition And Random mask diffusion Model (SWARM) for SVCT reconstruction. Specifically, introducing a random mask strategy in the sinogram effectively expands the limited training sample space. This enables the model to learn a broader range of data distributions, enhancing its understanding and generalization of data uncertainty. In addition, applying a random training strategy to the high-frequency components of the sinogram wavelet enhances feature representation and improves the ability to capture details in different frequency bands, thereby improving performance and robustness. Two-stage iterative reconstruction method is adopted to ensure the global consistency of the reconstructed image while refining its details. Experimental results demonstrate that SWARM outperforms competing approaches in both quantitative and qualitative performance across various datasets.

eess.IV↗

arXiv2024

Basis-independent Coherence and its Applications

In the quantitative theory of quantum coherence, the amount of coherence for given states can be meaningfully discussed only when referring to a preferred basis. One of the objections to this quantification is that the amount of coherence is an intrinsically basis-dependent quantity. This limitation can, however, be lifted when considering a set of quantum states invariant under arbitrary unitary transformations. Thus, we analyze a basis-independent definition of quantum coherence, and the incoherent state is taken as the maximally mixed state. We describe the relationship between the basis-independent and the basis-dependent approaches and give several applications to show the advantages of the former method. The relations among basis-independent coherence, quantum entanglement, and quantum discord are discussed by using the relative entropy within a multipartite system.

quant-ph↗

arXiv2024

Zeolitic Imidazolate Framework-8 offers an anti-inflammatory and antifungal method in the treatment of Aspergillus fungus keratitis in vitro and in vivo

Background: Fungal keratitis is a serious blinding eye disease. Traditional drugs used to treat fungal keratitis commonly have the disadvantages of low bioavailability, poor dispersion, and limited permeability. Purpose: To develop a new method for the treatment of fungal keratitis with improved bioavailability, dispersion, and permeability. Purpose: To develop a new method for the treatment of fungal keratitis with improved bioavailability, dispersion, and permeability. Methods: Zeolitic Imidazolate Framework-8 (ZIF-8) was formed by zinc ions and 2-methylimidazole linked by coordination bonds and characterized by Scanning electron microscopy (SEM), X-ray diffraction (XRD), and Zeta potential. The safety of ZIF-8 on HCECs and RAW 264.7 cells was detected by Cell Counting Kit-8 (CCK-8). The anti-inflammatory effects of ZIF-8 on RAW 246.7 cells were evaluated by Quantitative Real-Time PCR Experiments (qPCR) and Enzyme-linked immunosorbent assay (ELISA). Clinical score, Colony-Forming Units (CFU). In vivo, treatment with ZIF-8 reduced corneal fungal load and mitigated neutrophil infiltration in fungal keratitis, which effectively reduced the severity of keratitis in mice and alleviated the infiltration of inflammatory factors in the mouse cornea. In addition, ZIF-8 reduces the inflammatory response by downregulating the expression of pro-inflammatory cytokines TNF-{\alpha}, IL-6, and IL-1\b{eta} after Aspergillus fumigatus infection in vivo and in vitro. Conclusion: ZIF-8 has a significant anti-inflammatory and antifungal effect, which provides a new solution for the treatment of fungal keratitis.

q-bio.TO↗

arXiv2024

Solution landscape of reaction-diffusion systems reveals a nonlinear mechanism and spatial robustness of pattern formation

Spontaneous pattern formation in homogeneous systems is ubiquitous in nature. Although Turing demonstrated that spatial patterns can emerge in reaction-diffusion (RD) systems when the homogeneous state becomes linearly unstable, it remains unclear whether the Turing mechanism is the only route for pattern formation. Here, we develop an efficient algorithm to systematically map the solution landscape to find all steady-state solutions. By applying our method to generic RD models, we find that stable spatial patterns can emerge via saddle-node bifurcations before the onset of Turing instability. Furthermore, by using a generalized action in functional space based on large deviation theory, our method is extended to evaluate stability of spatial patterns against noise. Applying this general approach in a three-species RD model, we show that though formation of Turing patterns only requires two chemical species, the third species is critical for stabilizing patterns against strong intrinsic noise in small biochemical systems.

physics.bio-ph↗

arXiv2024

Deep learning for automated detection of breast cancer in deep ultraviolet fluorescence images with diffusion probabilistic model

Data limitation is a significant challenge in applying deep learning to medical images. Recently, the diffusion probabilistic model (DPM) has shown the potential to generate high-quality images by converting Gaussian random noise into realistic images. In this paper, we apply the DPM to augment the deep ultraviolet fluorescence (DUV) image dataset with an aim to improve breast cancer classification for intraoperative margin assessment. For classification, we divide the whole surface DUV image into small patches and extract convolutional features for each patch by utilizing the pre-trained ResNet. Then, we feed them into an XGBoost classifier for patch-level decisions and then fuse them with a regional importance map computed by Grad-CAM++ for whole surface-level prediction. Our experimental results show that augmenting the training dataset with the DPM significantly improves breast cancer detection performance in DUV images, increasing accuracy from 93% to 97%, compared to using Affine transformations and ProGAN.

cs.CV↗

arXiv2024

Genuinely nonlocal sets with smallest cardinality

Recently, there is growing interest in the study of genuine nonlocality, which serves to explore the local accessability of global information encoded in orthogonal multipartite quantum states under scenarios where not all subsystems are joined together. For such form of nonlocality, a probably most fundamental question is upon what states it is prone to be manifested. To tackle this, we present in this work genuinely nonlocal sets with the smallest possible cardinality. We first show the existence of genuinely nonlocal sets of three pure states in arbitrary N-partite system. As a byproduct, this also gives new examples of strongly nonlocal sets with dramatically smaller cardinality than ever for all possible systems, settling some related questions effortlessly. Then, for mixed hypothetical states, we show that genuinely nonlocal sets of two even exist, regardless of the number of copies available. In particular, it turns out for both our constructions that certain genuinely entangled states necessarily exist, nontrivially indicating their potential of raising difficulty in locally accessing multipartite quantum information.

quant-ph↗

arXiv2024

KS-Net: Multi-band joint speech restoration and enhancement network for 2024 ICASSP SSI Challenge

This paper presents the speech restoration and enhancement system created by the 1024K team for the ICASSP 2024 Speech Signal Improvement (SSI) Challenge. Our system consists of a generative adversarial network (GAN) in complex-domain for speech restoration and a fine-grained multi-band fusion module for speech enhancement. In the blind test set of SSI, the proposed system achieves an overall mean opinion score (MOS) of 3.49 based on ITU-T P.804 and a Word Accuracy Rate (WAcc) of 0.78 for the real-time track, as well as an overall P.804 MOS of 3.43 and a WAcc of 0.78 for the non-real-time track, ranking 1st in both tracks.

cs.SD↗

arXiv2023

BAE-Net: A Low complexity and high fidelity Bandwidth-Adaptive neural network for speech super-resolution

Speech bandwidth extension (BWE) has demonstrated promising performance in enhancing the perceptual speech quality in real communication systems. Most existing BWE researches primarily focus on fixed upsampling ratios, disregarding the fact that the effective bandwidth of captured audio may fluctuate frequently due to various capturing devices and transmission conditions. In this paper, we propose a novel streaming adaptive bandwidth extension solution dubbed BAE-Net, which is suitable to handle the low-resolution speech with unknown and varying effective bandwidth. To address the challenges of recovering both the high-frequency magnitude and phase speech content blindly, we devise a dual-stream architecture that incorporates the magnitude inpainting and phase refinement. For potential applications on edge devices, this paper also introduces BAE-NET-lite, which is a lightweight, streaming and efficient framework. Quantitative results demonstrate the superiority of BAE-Net in terms of both performance and computational efficiency when compared with existing state-of-the-art BWE methods.

cs.SD↗

arXiv2023

Enhanced quantum channel uncertainty relations by skew information

By revisiting the mathematical foundation of the uncertainty relation, skew information-based uncertainty sequences are developed for any two quantum channels. A reinforced version of the Cauchy-Schwarz inequality is adopted to improve the uncertainty relation, and a sampling technique of observables' coordinates is used to offset randomness in the inequality. It is shown that the lower bounds of the uncertainty relations are tighter than some previous studies.

quant-ph↗