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Hau-Tieng Wu

Publications and source records attributed to Hau-Tieng Wu.

82 records · Page 5Linked to original sources

Phenotype-based and Self-learning Inter-individual Sleep Apnea Screening with a Level IV Monitoring System

Purpose: We propose a phenotype-based artificial intelligence system that can self-learn and is accurate for screening purposes, and test it on a Level IV monitoring system. Methods: Based on the physiological knowledge, we hypothesize that the phenotype information will allow us to find subjects from a well-annotated database that share similar sleep apnea patterns. Therefore, for a new-arriving subject, we can establish a prediction model from the existing database that is adaptive to the subject. We test the proposed algorithm on a database consisting of 62 subjects with the signals recorded from a Level IV wearable device measuring the thoracic and abdominal movements and the SpO2. Results: With the leave-one cross validation, the accuracy of the proposed algorithm to screen subjects with an apnea-hypopnea index greater or equal to 15 is 93.6%, the positive likelihood ratio is 6.8, and the negative likelihood ratio is 0.03. Conclusion: The results confirm the hypothesis and show that the proposed algorithm has great potential to screen patients with SAS.

stat.AP↗

Embeddings of Riemannian Manifolds with Finite Eigenvector Fields of Connection Laplacian

We study the problem asking if one can embed manifolds into finite dimensional Euclidean spaces by taking finite number of eigenvector fields of the connection Laplacian. This problem is essential for the dimension reduction problem in massive data analysis. Singer-Wu proposed the vector diffusion map which embeds manifolds into the Hilbert space $l^2$ using eigenvectors of connection Laplacian. In this paper, we provide a positive answer to the problem. Specifically, we use eigenvector fields to construct local coordinate charts with low distortion, and show that the distortion constants depend only on geometric properties of manifolds with metrics in the little Hölder space $c^{2,α}$. Next, we use the coordinate charts to embed the entire manifold into a finite dimensional Euclidean space. The proof of the results relies on solving the elliptic system and provide estimates for eigenvector fields and the heat kernel and their gradients. We also provide approximation results for eigenvector field under the $c^{2,α}$ perturbation.

math.DG↗

How nonlinear-type time-frequency analysis can help in sensing instantaneous heart rate and instantaneous respiratory rate from photoplethysmography in a reliable way

Despite the population of the noninvasive, economic, comfortable, and easy-to-install photoplethysmography (PPG), it is still lacking a mathematically rigorous and stable algorithm which is able to simultaneously extract from a single-channel PPG signal the instantaneous heart rate (IHR) and the instantaneous respiratory rate (IRR). In this paper, a novel algorithm called deppG is provided to tackle this challenge. deppG is composed of two theoretically solid nonlinear-type time-frequency analyses techniques, the de-shape short time Fourier transform and the synchrosqueezing transform, which allows us to extract the instantaneous physiological information from the PPG signal in a reliable way. To test its performance, in addition to validating the algorithm by a simulated signal and discussing the meaning of "instantaneous", the algorithm is applied to two publicly available batch databases, the Capnobase and the ICASSP 2015 signal processing cup. The former contains PPG signals relative to spontaneous or controlled breathing in static patients, and the latter is made up of PPG signals collected from subjects doing intense physical activities. The accuracies of the estimated IHR and IRR are compared with the ones obtained by other methods, and represent the state-of-the-art in this field of research. The results suggest the potential of deppG to extract instantaneous physiological information from a signal acquired from widely available wearable devices, even when a subject carries out intense physical activities.

q-bio.NC↗

Think globally, fit locally under the Manifold Setup: Asymptotic Analysis of Locally Linear Embedding

Since its introduction in 2000, the locally linear embedding (LLE) has been widely applied in data science. We provide an asymptotical analysis of the LLE under the manifold setup. We show that for the general manifold, asymptotically we may not obtain the Laplace-Beltrami operator, and the result may depend on the non-uniform sampling, unless a correct regularization is chosen. We also derive the corresponding kernel function, which indicates that the LLE is not a Markov process. A comparison with the other commonly applied nonlinear algorithms, particularly the diffusion map, is provided, and its relationship with the locally linear regression is also discussed.

math.ST↗

Vector Nonlocal Euclidean Median: Principal Bundle Captures The Nature of Patch Space

We extensively study the rotational group structure inside the patch space by introducing the fiber bundle structure. The rotational group structure leads to a new image denoising algorithm called the \textit{vector non-local Euclidean median} (VNLEM). The theoretical aspect of VNLEM is studied, which explains why the VNLEM and traditional non-local mean/non-local Euclidean median (NLEM) algorithm work. The numerical issue of the VNLEM is improved by taking the orientation feature in the commonly applied scale-invariant feature transform (SIFT), and a theoretical analysis of the robustness of the orientation feature in the SIFT is provided. The VNLEM is applied to an image database of 1,361 images and compared with the NLEM. Different image quality assessments based on the error-sensitivity or the human visual system are applied to evaluate the performance. The results confirmed the potential of the VNLEM algorithm.

physics.data-an↗

Rank-1 accelerated illumination recovery in scanning diffractive imaging by transparency estimation

We consider the problem of blind ptychography, that is the joint estimation of an unknown object and an illumination function from diffraction intensity measurements. In ptychography, diffraction measurements from neighboring regions of the same object are related to each other by a pairwise relationship between overlapping frames. When the illumination is well known, the relationship among frames is given by a linear projection operator. We propose a power iteration-projection algorithm that minimizes the global pairwise discrepancy among frames. We accelerate the convergence of power method by subtracting the estimated localized average transparency of the unknown object. The method is effective for weakly scattering and low contrast objects or piecewise smooth specimens.

math.OC↗

A New Test for One-Way ANOVA with Functional Data and Application to Ischemic Heart Screening

We propose and study a new global test, namely the $F_{\max}$-test, for the one-way ANOVA problem in functional data analysis. The test statistic is taken as the maximum value of the usual pointwise $F$-test statistics over the interval the functional responses are observed. A nonparametric bootstrap method is employed to approximate the null distribution of the test statistic and to obtain an estimated critical value for the test. The asymptotic random expression of the test statistic is derived and the asymptotic power is studied. In particular, under mild conditions, the $F_{\max}$-test asymptotically has the correct level and is root-$n$ consistent in detecting local alternatives. Via some simulation studies, it is found that in terms of both level accuracy and power, the $F_{\max}$-test outperforms the Globalized Pointwise F (GPF) test of \cite{Zhang_Liang:2013} when the functional data are highly or moderately correlated, and its performance is comparable with the latter otherwise. An application to an ischemic heart real dataset suggests that, after proper manipulation, resting electrocardiogram (ECG) signals can be used as an effective tool in clinical ischemic heart screening, without the need of further stress tests as in the current standard procedure.

math.ST↗

The Synchrosqueezing algorithm for time-varying spectral analysis: robustness properties and new paleoclimate applications

We analyze the stability properties of the Synchrosqueezing transform, a time-frequency signal analysis method that can identify and extract oscillatory components with time-varying frequency and amplitude. We show that Synchrosqueezing is robust to bounded perturbations of the signal and to Gaussian white noise. These results justify its applicability to noisy or nonuniformly sampled data that is ubiquitous in engineering and the natural sciences. We also describe a practical implementation of Synchrosqueezing and provide guidance on tuning its main parameters. As a case study in the geosciences, we examine characteristics of a key paleoclimate change in the last 2.5 million years, where Synchrosqueezing provides significantly improved insights.

math.CA↗

Synchrosqueezing-based Recovery of Instantaneous Frequency from Nonuniform Samples

We propose a new approach for studying the notion of the instantaneous frequency of a signal. We build on ideas from the Synchrosqueezing theory of Daubechies, Lu and Wu and consider a variant of Synchrosqueezing, based on the short-time Fourier transform, to precisely define the instantaneous frequencies of a multi-component AM-FM signal. We describe an algorithm to recover these instantaneous frequencies from the uniform or nonuniform samples of the signal and show that our method is robust to noise. We also consider an alternative approach based on the conventional, Hilbert transform-based notion of instantaneous frequency to compare to our new method. We use these methods on several test cases and apply our results to a signal analysis problem in electrocardiography.

math.NA↗

Synchrosqueezed Wavelet Transforms: a Tool for Empirical Mode Decomposition

The EMD algorithm, first proposed in [11], made more robust as well as more versatile in [12], is a technique that aims to decompose into their building blocks functions that are the superposition of a (reasonably) small number of components, well separated in the time-frequency plane, each of which can be viewed as approximately harmonic locally, with slowly varying amplitudes and frequencies. The EMD has already shown its usefulness in a wide range of applications including meteorology, structural stability analysis, medical studies -- see, e.g. [13]. On the other hand, the EMD algorithm contains heuristic and ad-hoc elements that make it hard to analyze mathematically. In this paper we describe a method that captures the flavor and philosophy of the EMD approach, albeit using a different approach in constructing the components. We introduce a precise mathematical definition for a class of functions that can be viewed as a superposition of a reasonably small number of approximately harmonic components, and we prove that our method does indeed succeed in decomposing arbitrary functions in this class. We provide several examples, for simulated as well as real data.

math.NA↗