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Pierre Jannin

Publications and source records attributed to Pierre Jannin.

At least 19 recordsLinked to original sources

Hallucinations and Constraints : Regulating surgical workflow recognition beyond accuracy

Hallucinations are a major concern for the integration of artificial intelligence into medicine, although less explored in the realm of medical image processing. Unlike problems in natural text understanding and reasoning therewith, determining whether or not predictions derived from biomedical images and signals is less intuitively clear. This article suggests that topological errors could constitute hallucinations in a way that can be more readily measured and thus regulated. Certain of these properties for certain types of problems, such as biomedical signal segmentation, can be rephrased as linear temporal logic predicates, a number of which can be explicitly enforced using probabilistic graphical models. Our simulations show the potential of these explicitly constrained predicates for the case of automatic surgical phase recognition in robot-assisted hysterectomy, improving accuracy by approximately 10% while removing the vast majority of topological errors, suggesting that mathematical guarantees of correctness can supplement other empirical forms of regulating machine learning in medical image computing and computer-assisted interventions.

cs.LG

Disentangling Prompt Dependence to Evaluate Segmentation Reliability in Gynecological MRI

Promptable segmentation models (e.g., the Segment Anything Models) enable generalizable, zero-shot segmentation across diverse domains. Although predictions are deterministic for a fixed image-prompt pair, the robustness of these models to variations in user prompts, referred to as prompt dependence, remains underexplored. In safety-critical workflows with substantial inter-user variability, interpretable and informative frameworks are needed to evaluate prompt dependence. In this work, we assess the reliability of promptable segmentation by analyzing and measuring its sensitivity to prompt variability. We introduce the first formulation of prompt dependence that explicitly disentangles prompt ambiguity (inter-user variability) from local sensitivity (interaction imprecision), offering an interpretable view of segmentation robustness. Experiments on two female pelvic MRI datasets for uterus and bladder segmentation reveal a strong negative correlation between both metrics and segmentation performance, highlighting the value of our framework for assessing robustness. The two metrics have low mutual correlation, supporting the disentangled design of our formulation, and provide meaningful indicators of prompt-related failure modes.

cs.CV

DSTED: Decoupling Temporal Stabilization and Discriminative Enhancement for Surgical Workflow Recognition

Purpose: Surgical workflow recognition enables context-aware assistance and skill assessment in computer-assisted interventions. Despite recent advances, current methods suffer from two critical challenges: prediction jitter across consecutive frames and poor discrimination of ambiguous phases. This paper aims to develop a stable framework by selectively propagating reliable historical information and explicitly modeling uncertainty for hard sample enhancement. Methods: We propose a dual-pathway framework DSTED with Reliable Memory Propagation (RMP) and Uncertainty-Aware Prototype Retrieval (UPR). RMP maintains temporal coherence by filtering and fusing high-confidence historical features through multi-criteria reliability assessment. UPR constructs learnable class-specific prototypes from high-uncertainty samples and performs adaptive prototype matching to refine ambiguous frame representations. Finally, a confidence-driven gate dynamically balances both pathways based on prediction certainty. Results: Our method achieves state-of-the-art performance on AutoLaparo-hysterectomy with 84.36% accuracy and 65.51% F1-score, surpassing the second-best method by 3.51% and 4.88% respectively. Ablations reveal complementary gains from RMP (2.19%) and UPR (1.93%), with synergistic effects when combined. Extensive analysis confirms substantial reduction in temporal jitter and marked improvement on challenging phase transitions. Conclusion: Our dual-pathway design introduces a novel paradigm for stable workflow recognition, demonstrating that decoupling the modeling of temporal consistency and phase ambiguity yields superior performance and clinical applicability.

cs.CV

Current validation practice undermines surgical AI development

Surgical data science (SDS) is rapidly advancing, yet clinical adoption of artificial intelligence (AI) in surgery remains limited, with inadequate validation as an important contributing factor. Existing validation practices often neglect the temporal and hierarchical structure of intraoperative videos, yielding misleading or clinically irrelevant results. We introduce a comprehensive catalogue of validation pitfalls in AI-based surgical video analysis, derived from a multi-stage Delphi process with 92 international experts. Pitfalls span three categories: (1) data, (2) metric selection/configuration, and (3) aggregation and reporting. A systematic review of surgical AI papers reveals that these pitfalls are widespread. Experiments on surgical video datasets show that ignoring temporal and hierarchical data structures can understate uncertainty, obscure critical failure modes, and alter algorithm rankings. To address these shortcomings, we provide consensus-based best practices compiled. Together, this work provides an evidence-based framework for rigorous validation of surgical video analysis algorithms, guiding benchmarking, reporting, regulatory review, and clinical translation.

q-bio.OT

MerGen: Micro-electrode recording synthesis using a generative data-driven approach

The analysis of electrophysiological data is crucial for certain surgical procedures such as deep brain stimulation, which has been adopted for the treatment of a variety of neurological disorders. During the procedure, auditory analysis of these signals helps the clinical team to infer the neuroanatomical location of the stimulation electrode and thus optimize clinical outcomes. This task is complex, and requires an expert who in turn requires significant training. In this paper, we propose a generative neural network, called MerGen, capable of simulating de novo electrophysiological recordings, with a view to providing a realistic learning tool for clinicians trainees for identifying these signals. We demonstrate that the generated signals are perceptually indistinguishable from real signals by experts in the field, and that it is even possible to condition the generation efficiently to provide a didactic simulator adapted to a particular surgical scenario. The efficacy of this conditioning is demonstrated, comparing it to intra-observer and inter-observer variability amongst experts. We also demonstrate the use of this network for data augmentation for automatic signal classification which can play a role in decision-making support in the operating theatre.

cs.LG

Measuring proximity to standard planes during fetal brain ultrasound scanning

This paper presents a pipeline designed to bring ultrasound (US) plane pose estimation closer to clinical use, demonstrating the feasibility of continuous, real-time proximity feedback for navigation to the standard planes (SPs) in the fetal brain. We propose a semi-supervised segmentation model that uses labeled SPs and unlabeled slices from 3D US volumes (non-SPs), achieving 0.93 mean Intersection over Union (mIoU) on SPs and 0.86 mIoU on arbitrary non-SPs. The model incorporates a classification mechanism to identify and filter out frames lacking the fetal brain, and to generate masks for those containing it, enhancing the relevance of plane pose regression in clinical settings. Combined with 6D plane pose regression, our pipeline provides sensorless, continuous proximity detection to SPs with real-time distance metrics rather than binary plane recognition. Furthermore, we validate its translational viability by deploying the system on an NVIDIA Clara AGX edge device, achieving a real-time inference speed of 39 Hz, which exceeds standard clinical acquisition rates. Unlike prior methods validated on curated volume slices, we evaluate the pipeline retrospectively on real fetal scan videos from 17 sonographers of varying expertise: operators freeze near, rather than exactly at, the local minima of the proximity signal, consistent with clinical freeze-timing behavior, whereas proximity alone does not predict expert SP quality scores. The approach complements existing fetal US technologies and is a step toward image-based navigation support in prenatal scanning.

cs.CV

Why is the winner the best?

International benchmarking competitions have become fundamental for the comparative performance assessment of image analysis methods. However, little attention has been given to investigating what can be learnt from these competitions. Do they really generate scientific progress? What are common and successful participation strategies? What makes a solution superior to a competing method? To address this gap in the literature, we performed a multi-center study with all 80 competitions that were conducted in the scope of IEEE ISBI 2021 and MICCAI 2021. Statistical analyses performed based on comprehensive descriptions of the submitted algorithms linked to their rank as well as the underlying participation strategies revealed common characteristics of winning solutions. These typically include the use of multi-task learning (63%) and/or multi-stage pipelines (61%), and a focus on augmentation (100%), image preprocessing (97%), data curation (79%), and postprocessing (66%). The "typical" lead of a winning team is a computer scientist with a doctoral degree, five years of experience in biomedical image analysis, and four years of experience in deep learning. Two core general development strategies stood out for highly-ranked teams: the reflection of the metrics in the method design and the focus on analyzing and handling failure cases. According to the organizers, 43% of the winning algorithms exceeded the state of the art but only 11% completely solved the respective domain problem. The insights of our study could help researchers (1) improve algorithm development strategies when approaching new problems, and (2) focus on open research questions revealed by this work.

cs.CV

Understanding metric-related pitfalls in image analysis validation

Validation metrics are key for the reliable tracking of scientific progress and for bridging the current chasm between artificial intelligence (AI) research and its translation into practice. However, increasing evidence shows that particularly in image analysis, metrics are often chosen inadequately in relation to the underlying research problem. This could be attributed to a lack of accessibility of metric-related knowledge: While taking into account the individual strengths, weaknesses, and limitations of validation metrics is a critical prerequisite to making educated choices, the relevant knowledge is currently scattered and poorly accessible to individual researchers. Based on a multi-stage Delphi process conducted by a multidisciplinary expert consortium as well as extensive community feedback, the present work provides the first reliable and comprehensive common point of access to information on pitfalls related to validation metrics in image analysis. Focusing on biomedical image analysis but with the potential of transfer to other fields, the addressed pitfalls generalize across application domains and are categorized according to a newly created, domain-agnostic taxonomy. To facilitate comprehension, illustrations and specific examples accompany each pitfall. As a structured body of information accessible to researchers of all levels of expertise, this work enhances global comprehension of a key topic in image analysis validation.

cs.CV

Metrics reloaded: Recommendations for image analysis validation

Increasing evidence shows that flaws in machine learning (ML) algorithm validation are an underestimated global problem. Particularly in automatic biomedical image analysis, chosen performance metrics often do not reflect the domain interest, thus failing to adequately measure scientific progress and hindering translation of ML techniques into practice. To overcome this, our large international expert consortium created Metrics Reloaded, a comprehensive framework guiding researchers in the problem-aware selection of metrics. Following the convergence of ML methodology across application domains, Metrics Reloaded fosters the convergence of validation methodology. The framework was developed in a multi-stage Delphi process and is based on the novel concept of a problem fingerprint - a structured representation of the given problem that captures all aspects that are relevant for metric selection, from the domain interest to the properties of the target structure(s), data set and algorithm output. Based on the problem fingerprint, users are guided through the process of choosing and applying appropriate validation metrics while being made aware of potential pitfalls. Metrics Reloaded targets image analysis problems that can be interpreted as a classification task at image, object or pixel level, namely image-level classification, object detection, semantic segmentation, and instance segmentation tasks. To improve the user experience, we implemented the framework in the Metrics Reloaded online tool, which also provides a point of access to explore weaknesses, strengths and specific recommendations for the most common validation metrics. The broad applicability of our framework across domains is demonstrated by an instantiation for various biological and medical image analysis use cases.

cs.CV

PEg TRAnsfer Workflow recognition challenge report: Does multi-modal data improve recognition?

This paper presents the design and results of the "PEg TRAnsfert Workflow recognition" (PETRAW) challenge whose objective was to develop surgical workflow recognition methods based on one or several modalities, among video, kinematic, and segmentation data, in order to study their added value. The PETRAW challenge provided a data set of 150 peg transfer sequences performed on a virtual simulator. This data set was composed of videos, kinematics, semantic segmentation, and workflow annotations which described the sequences at three different granularity levels: phase, step, and activity. Five tasks were proposed to the participants: three of them were related to the recognition of all granularities with one of the available modalities, while the others addressed the recognition with a combination of modalities. Average application-dependent balanced accuracy (AD-Accuracy) was used as evaluation metric to take unbalanced classes into account and because it is more clinically relevant than a frame-by-frame score. Seven teams participated in at least one task and four of them in all tasks. Best results are obtained with the use of the video and the kinematics data with an AD-Accuracy between 93% and 90% for the four teams who participated in all tasks. The improvement between video/kinematic-based methods and the uni-modality ones was significant for all of the teams. However, the difference in testing execution time between the video/kinematic-based and the kinematic-based methods has to be taken into consideration. Is it relevant to spend 20 to 200 times more computing time for less than 3% of improvement? The PETRAW data set is publicly available at www.synapse.org/PETRAW to encourage further research in surgical workflow recognition.

cs.LG

Towards responsible research in digital technology for health care

Digital technology is everywhere for the benefit of our daily and professional life. It strongly impacts our life and was crucial to maintain professional and social activities during the COVID19 crisis. Similarly, digital technologies are key within biomedical engineering research topics. Innovations have been generated and introduced over the last 40 years, demonstrating how computing and digital technologies have impacted health care. Although the benefits of digital technology are obvious now, we are at the convergence of several issues which makes us aware about social, societal and environmental challenges associated with this technology. In the social domain, digital technologies raise concern about exclusion (financial, geographical, educational, demographical, racial, gender, language, and disabled related exclusion) and physical and mental health. In the societal dimension, digital technologies raise concern about politics and democracy (sovereignty and governance, cognitive filters and citizen's engagement), privacy and security (data acquisition and usage transparency, level of personal approval, and level of anonymization), and economics. In the environmental dimension, digital technologies raise concern about energy consumption and hardware production. This paper introduces and defines these challenges for digital technology in general, as well as when applied to health care. The objective of this paper is to make the research community more aware about the challenges of digital technology and to promote more transparency for innovative and responsible research.

cs.CY

Common Limitations of Image Processing Metrics: A Picture Story

While the importance of automatic image analysis is continuously increasing, recent meta-research revealed major flaws with respect to algorithm validation. Performance metrics are particularly key for meaningful, objective, and transparent performance assessment and validation of the used automatic algorithms, but relatively little attention has been given to the practical pitfalls when using specific metrics for a given image analysis task. These are typically related to (1) the disregard of inherent metric properties, such as the behaviour in the presence of class imbalance or small target structures, (2) the disregard of inherent data set properties, such as the non-independence of the test cases, and (3) the disregard of the actual biomedical domain interest that the metrics should reflect. This living dynamically document has the purpose to illustrate important limitations of performance metrics commonly applied in the field of image analysis. In this context, it focuses on biomedical image analysis problems that can be phrased as image-level classification, semantic segmentation, instance segmentation, or object detection task. The current version is based on a Delphi process on metrics conducted by an international consortium of image analysis experts from more than 60 institutions worldwide.

eess.IV

MIcro-Surgical Anastomose Workflow recognition challenge report

The "MIcro-Surgical Anastomose Workflow recognition on training sessions" (MISAW) challenge provided a data set of 27 sequences of micro-surgical anastomosis on artificial blood vessels. This data set was composed of videos, kinematics, and workflow annotations described at three different granularity levels: phase, step, and activity. The participants were given the option to use kinematic data and videos to develop workflow recognition models. Four tasks were proposed to the participants: three of them were related to the recognition of surgical workflow at three different granularity levels, while the last one addressed the recognition of all granularity levels in the same model. One ranking was made for each task. We used the average application-dependent balanced accuracy (AD-Accuracy) as the evaluation metric. This takes unbalanced classes into account and it is more clinically relevant than a frame-by-frame score. Six teams, including a non-competing team, participated in at least one task. All models employed deep learning models, such as CNN or RNN. The best models achieved more than 95% AD-Accuracy for phase recognition, 80% for step recognition, 60% for activity recognition, and 75% for all granularity levels. For high levels of granularity (i.e., phases and steps), the best models had a recognition rate that may be sufficient for applications such as prediction of remaining surgical time or resource management. However, for activities, the recognition rate was still low for applications that can be employed clinically. The MISAW data set is publicly available to encourage further research in surgical workflow recognition. It can be found at www.synapse.org/MISAW

cs.LG

Surgical Data Science -- from Concepts toward Clinical Translation

Recent developments in data science in general and machine learning in particular have transformed the way experts envision the future of surgery. Surgical Data Science (SDS) is a new research field that aims to improve the quality of interventional healthcare through the capture, organization, analysis and modeling of data. While an increasing number of data-driven approaches and clinical applications have been studied in the fields of radiological and clinical data science, translational success stories are still lacking in surgery. In this publication, we shed light on the underlying reasons and provide a roadmap for future advances in the field. Based on an international workshop involving leading researchers in the field of SDS, we review current practice, key achievements and initiatives as well as available standards and tools for a number of topics relevant to the field, namely (1) infrastructure for data acquisition, storage and access in the presence of regulatory constraints, (2) data annotation and sharing and (3) data analytics. We further complement this technical perspective with (4) a review of currently available SDS products and the translational progress from academia and (5) a roadmap for faster clinical translation and exploitation of the full potential of SDS, based on an international multi-round Delphi process.

cs.CY

Towards Generalizable Surgical Activity Recognition Using Spatial Temporal Graph Convolutional Networks

Modeling and recognition of surgical activities poses an interesting research problem. Although a number of recent works studied automatic recognition of surgical activities, generalizability of these works across different tasks and different datasets remains a challenge. We introduce a modality that is robust to scene variation, and that is able to infer part information such as orientational and relative spatial relationships. The proposed modality is based on spatial temporal graph representations of surgical tools in videos, for surgical activity recognition. To explore its effectiveness, we model and recognize surgical gestures with the proposed modality. We construct spatial graphs connecting the joint pose estimations of surgical tools. Then, we connect each joint to the corresponding joint in the consecutive frames forming inter-frame edges representing the trajectory of the joint over time. We then learn hierarchical spatial temporal graph representations using Spatial Temporal Graph Convolutional Networks (ST-GCN). Our experiments show that learned spatial temporal graph representations perform well in surgical gesture recognition even when used individually. We experiment with the Suturing task of the JIGSAWS dataset where the chance baseline for gesture recognition is 10%. Our results demonstrate 68% average accuracy which suggests a significant improvement. Learned hierarchical spatial temporal graph representations can be used either individually, in cascades or as a complementary modality in surgical activity recognition, therefore provide a benchmark for future studies. To our knowledge, our paper is the first to use spatial temporal graph representations of surgical tools, and pose-based skeleton representations in general, for surgical activity recognition.

cs.CV

BIAS: Transparent reporting of biomedical image analysis challenges

The number of biomedical image analysis challenges organized per year is steadily increasing. These international competitions have the purpose of benchmarking algorithms on common data sets, typically to identify the best method for a given problem. Recent research, however, revealed that common practice related to challenge reporting does not allow for adequate interpretation and reproducibility of results. To address the discrepancy between the impact of challenges and the quality (control), the Biomedical I mage Analysis ChallengeS (BIAS) initiative developed a set of recommendations for the reporting of challenges. The BIAS statement aims to improve the transparency of the reporting of a biomedical image analysis challenge regardless of field of application, image modality or task category assessed. This article describes how the BIAS statement was developed and presents a checklist which authors of biomedical image analysis challenges are encouraged to include in their submission when giving a paper on a challenge into review. The purpose of the checklist is to standardize and facilitate the review process and raise interpretability and reproducibility of challenge results by making relevant information explicit.

cs.CV

Offline identification of surgical deviations in laparoscopic rectopexy

Objective: A median of 14.4% of patient undergone at least one adverse event during surgery and a third of them are preventable. The occurrence of adverse events forces surgeons to implement corrective strategies and, thus, deviate from the standard surgical process. Therefore, it is clear that the automatic identification of adverse events is a major challenge for patient safety. In this paper, we have proposed a method enabling us to identify such deviations. We have focused on identifying surgeons' deviations from standard surgical processes due to surgical events rather than anatomic specificities. This is particularly challenging, given the high variability in typical surgical procedure workflows. Methods: We have introduced a new approach designed to automatically detect and distinguish surgical process deviations based on multi-dimensional non-linear temporal scaling with a hidden semi-Markov model using manual annotation of surgical processes. The approach was then evaluated using cross-validation. Results: The best results have over 90% accuracy. Recall and precision were superior at 70%. We have provided a detailed analysis of the incorrectly-detected observations. Conclusion: Multi-dimensional non-linear temporal scaling with a hidden semi-Markov model provides promising results for detecting deviations. Our error analysis of the incorrectly-detected observations offers different leads in order to further improve our method. Significance: Our method demonstrated the feasibility of automatically detecting surgical deviations that could be implemented for both skill analysis and developing situation awareness-based computer-assisted surgical systems.

eess.IV

Surgical Gesture Recognition with Optical Flow only

In this paper, we address the open research problem of surgical gesture recognition using motion cues from video data only. We adapt Optical flow ConvNets initially proposed by Simonyan et al.. While Simonyan uses both RGB frames and dense optical flow, we use only dense optical flow representations as input to emphasize the role of motion in surgical gesture recognition, and present it as a robust alternative to kinematic data. We also overcome one of the limitations of Optical flow ConvNets by initializing our model with cross modality pre-training. A large number of promising studies that address surgical gesture recognition highly rely on kinematic data which requires additional recording devices. To our knowledge, this is the first paper that addresses surgical gesture recognition using dense optical flow information only. We achieve competitive results on JIGSAWS dataset, moreover, our model achieves more robust results with less standard deviation, which suggests optical flow information can be used as an alternative to kinematic data for the recognition of surgical gestures.

cs.CV