arXiv subjects

Yutong Xie

Publications and source records attributed to Yutong Xie.

At least 19 recordsLinked to original sources

arXiv2026

DoAtlas-2: A Foundation for Self-Evolving Causal Biomedical Discovery

We introduce DoAtlas-2, a foundation for self-evolving causal biomedical discovery that organizes knowledge around causal mechanisms and advances through external evidence from human populations. DoAtlas-2 integrates 771 research resources covering more than 720,000 participants in 48 countries, from longitudinal clinical phenotypes, medical imaging, and continuous physiological signals to eight molecular layers, together with an evidence network of approximately 4.7 million literature-derived records over 93,566 concepts and 149,383 candidate causal relations. DoAtlas-2 autonomously formulates research questions from evidence gaps and unresolved mechanisms, prespecifies their causal designs, and generates validated analyses. Supporting, challenging, and unresolved results continuously revise mechanistic interpretations, the causal evidence state, and the discovery frontier, so that DoAtlas-2 self-evolves within a closed loop of hypothesis generation, empirical testing, and renewed discovery. DoAtlas-2 has systematically evaluated 2,031 research questions. In the Human Phenotype Project (HPP), it formulated 4,014 candidate pathway questions across vascular, early-glycemic, and hepatic-metabolic systems, and screening of the first 1,079 yielded statistical support for 756. Representative studies identify blood pressure as a convergence node linking adiposity, hepatic, and lipid phenotypes to vascular outcomes, and show that an adiposity-inflammation-blood-pressure pathway is largely attenuated by joint adjustment for body mass index (BMI) and smoking. The discovered vascular network constitutes a completely interpretable predictive foundation, admitting exact attribution of every prediction and closed-form mediation effects. DoAtlas-2 thereby unifies causal mechanism discovery, population-evidence testing, and interpretable prediction within one continuously evolving foundation.

cs.AI↗

arXiv2026

A misinformation playbook sharpens judgement without breeding cynicism

Misinformation harms public health and democracy, and generative artificial intelligence now writes falsehoods as persuasive as people's. Defences range from fact-checking individual claims to training people to resist falsehoods. Yet many claims are too new to check, and interventions that teach doubt can reduce belief in truth too. We propose a defence that targets not the facts of each claim but the persuasion strategies that recur across them. Here we show that learning misinformation's persuasion playbook, mapped from 214,646 fact-checked claims in 51 languages, can sharpen human and machine judgement of claims they know little about, without making either more cynical about true claims. The playbook spans social influence, information manipulation and emotional appeals, combined around a core of fear, conspiracy and fabrication. Briefed with it, plus a reminder that persuasion is not proof of falsehood, a language model better distinguished true from machine-generated false claims about events after its training data. In a pre-registered experiment, the same briefing improved people's discernment of claims they reported as unfamiliar and left their belief in true claims unchanged. Averaged over all claims, the gain was not statistically significant. Because it targets what recurs, this defence need not wait for claim-specific fact-checks.

cs.CY↗

arXiv2026

BehaviorBench: Benchmarking Foundation Models for Behavioral Science Tasks

Foundation models have been increasingly applied to behavioral science domains such as psychology, sociology, and economics. While these models show promise in tasks such as survey response prediction and human-subject experiment simulation, there remains no systematic understanding of how well they perform across diverse behavioral science tasks. We introduce BehaviorBench, a comprehensive benchmark that evaluates foundation models along four core capabilities: (1) behavior prediction and simulation, (2) strategic decision-making, (3) subject-trait inference, and (4) behavioral knowledge application. Crucially, BehaviorBench evaluates model outputs at both the individual and distributional levels, capturing not only per-subject accuracy but also population-level alignment, an essential requirement for behavioral validity. Our evaluation shows that BehaviorBench remains challenging for leading general-purpose LLMs and behavior foundation models that are specifically trained with behavioral data. We find that individual-level and distributional performance do not always align. General-purpose LLMs tend to underestimate the diversity of human responses, whereas behavior foundation models often lag behind at individual-level prediction. Our investigation further demonstrates how fine-tuning on diverse behavioral data can improve both individual-level prediction and distributional alignment, balancing these two objectives. Our results highlight the importance of evaluation at both individual and distributional levels, establishing BehaviorBench as a foundation for developing and assessing behaviorally aligned AI systems. Our BehaviorBench and models can be accessed via https://umich-foreseer.github.io/behaviorbench/

cs.CL↗

arXiv2026

Do Not Train Away Uncertainty: Early Uncertainty Anchored Calibration

Deep neural networks, including large language models, have achieved remarkable performance across various tasks. However, they are prone to overconfidence during training or fine-tuning. In this work, we observe a consistent phenomenon across different models that the early model is better calibrated, while later training or fine-tuning yields marginal accuracy gains but substantially increases calibration errors. Our analysis suggests that the early model retains uncertainty awareness in both its predictions and features, which is gradually lost with continued training. To avoid training away this uncertainty awareness, we propose \textbf{EUA-Cal}, a novel method that exploits the \textbf{E}arly model as an \textbf{U}ncertainty \textbf{A}nchor for \textbf{Cal}ibration. EUA-Cal introduces early prediction regularization to preserve early predictive uncertainty and prototype structure regularization to exploit uncertainty reflected in the early feature space, jointly mitigating overconfidence. Extensive experiments on image classification and multiple-choice question answering across eight diverse models demonstrate that EUA-Cal outperforms state-of-the-art calibration methods.

cs.CV↗

arXiv2026

HouseholdBench: Evaluating Large Language Models as Predictors of Household Economic Behavior

Large language models (LLMs) have the potential to meet a key goal in economics: a quantitative model of household decision making, across a variety of settings. Yet existing evaluations cover few surveys and outcomes, and do not study how households adjust to changing economic conditions. We introduce a new evaluation, HouseholdBench, which unites 6 U.S. household surveys and 32 prediction tasks spanning numeric, categorical and probabilistic outcomes, related to consumption, income, labor, expectations, and housing. Using past behavior, demographics and macroeconomic conditions, the tasks test whether LLMs predict behavior, including how households adjust to changes in various policies. We evaluate 13 proprietary and open-weight LLMs against a no-change baseline and a gradient-boosted tree model. Most LLMs outperform the no-change baseline, including for policy response tasks -- with the best model lowering error for numeric outcomes by 12.2%. Across most tasks, gradient-boosted trees rank first; leading proprietary LLMs approach their performance, but open-weight models lag. LLMs exhibit systematic over- and underprediction across different tasks. We identify methods that enable a 4 billion parameter open-weight model to match proprietary models' performance: fine-tuning and aggregating 16 predictions per observation. Improvements generalize to policy-response tasks, which are excluded from fine-tuning. We release our datasets, code, and leaderboard on our website: https://jn-huang.github.io/householdbench

cs.CL↗

arXiv2026

Vocabulary-Incomplete Unsupervised Vision-Language Model Adaptation

In certain real-world scenarios, obtaining labeled data is excessively expensive, motivating increasing interest in adapting models without annotations. Vision-language models (VLMs) provide pseudo-labels for unlabeled images through image-text similarity, enabling adaptation without manual labeling. The previous unsupervised vision-language model adaption methods assume access to an adaptation vocabulary containing all class names. However, a complete vocabulary is difficult to construct in real-world scenarios, as unlabeled data may contain classes that are overlooked or fall outside the current task scope. Thus, we propose Vocabulary-Incomplete Unsupervised Vision-language model Adaptation (VI-UVA), where only a subset of class names are available during adaptation. The vocabulary incompleteness induces an adaptation bias toward provided classes, which degrades omitted-class recognition. To address this issue, we propose Label Space Reconstruction (LSR), which reconstructs a latent label space from the unlabeled data and incorporates it into prompt tuning, thereby extending adaptation beyond the incomplete vocabulary and mitigating the adaptation bias. Furthermore, we derive an omitted-class semantic discrepancy bound for LSR and identify the key factors affecting the bound. Extensive experiments across eight benchmarks demonstrate that LSR outperforms existing state-of-the-art methods.

cs.CV↗

arXiv2026

AI Behavioral Science: A Framework and Agenda

We discuss the challenges and opportunities present in the rapidly emerging area of ``AI Behavioral Science.'' We frame it via three subfields. First, as AI becomes ubiquitous and is increasingly proprietary and opaque, it becomes vital to develop models of AI and methods for assessing AI behavior. We outline how tools developed to assess people's behaviors by social scientists can be used to model, assess and infer AI's behaviors biases, tendencies, and heuristics. Second, we also discuss how AI can change the ways in which we learn about human behavior. Beyond its computational power, AI offers new techniques for simulating, inferring, predicting, and analyzing human behaviors. Third, as humans and AI are interacting in increasingly complex and intertwined systems, we need to analyze and model human-AI interactions including how human and AI behaviors depend on interactions at the individual level, how interacting systems of humans and AI behave, and ultimately how AI's integration into society affects economic and political outcomes. We discuss current research, questions, agendas, and goals in each of these three subfields and how they depend upon each other.

cs.HC↗

arXiv2026

Modeling Human Behavior with Type Vectors Using AI

We introduce a general, easy-to-implement AI-based modeling technique for analyzing human behavior. A key feature of this approach, which contrasts with existing modeling techniques, is that it combines the flexibility and interpretability of natural language with a mathematical structure that can be fitted to data and easily analyzed. We assign a large language model a vector of trait intensities-a type vector-and then ask it to choose actions across settings in which we observe human choices. For instance, the type vector (2,4) could correspond to "You are a player characterized by the following profile: Altruism: 2 out of 5, Risk Aversion: 4 out of 5," after which it is asked to make choices. We can then vary the traits (e.g., Altruism, Fairness, Trust,...) and values (e.g., 1-5) to minimize distance to human choices. We illustrate the method by applying it to model 119,147 decisions made by 78,657 subjects from more than 35 countries across 10 classic economic game roles. We find that human behavior can be closely matched using three dimensions: Risk Aversion, Strategic Sophistication, and Trust. The type vectors needed to fit individuals across games cluster into fewer than a dozen groups, with substantial variation in fit across subjects. Moreover, the individual type vectors can predict behavior in held-out games with different rules and available actions. More broadly, this new modeling method is highly generalizable and interpretable: we can input any vector of traits and use them to model behavior across any setting

econ.TH↗

arXiv2026

Beyond the Foreground: FOV-Aware Polyp Image Synthesis via Lesion-Guided Adaptive Mucosal Context Propagation

Synthetic image and mask pairs can alleviate scarce colonoscopy annotations, but realistic synthesis requires preserving the supplied lesion while generating compatible mucosa. Existing foreground-guided methods treat all non-foreground pixels as background and rely mainly on local integration. Directly applying them to colonoscopy causes two problems: non-mucosal black regions contaminate generated tissue, and local reasoning produces inconsistent mucosal texture and illumination. We propose LAMP, the first foreground-guided framework for polyp image synthesis based on lesion-guided adaptive mucosal context propagation. LAMP explicitly separates the lesion, valid mucosa, and camera exterior using a field-of-view (FOV) mask. Lesion-to-Mucosa cross-attention extracts lesion appearance conditions for valid-mucosa locations, while FOV-constrained multidirectional Vision Receptance Weighted Key Value propagates them over legal tissue support. An adaptive gate then controls their residual fusion into the diffusion U-Net. Extensive experiments on five polyp datasets demonstrate that LAMP substantially outperforms existing methods in overall generation quality and consistently improves five downstream segmentation models. Our code will be released at https://github.com/wangtong627/LAMP.

cs.CV↗

arXiv2026

PathoHR: Breast Cancer Survival Prediction on High-Resolution Pathological Images

Breast cancer survival prediction in computational pathology presents a remarkable challenge due to tumor heterogeneity. For instance, different regions of the same tumor in the pathology image can show distinct morphological and molecular characteristics. This makes it difficult to extract representative features from whole slide images (WSIs) that truly reflect the tumor's aggressive potential and likely survival outcomes. In this paper, we present PathoHR, a novel pipeline for accurate breast cancer survival prediction that enhances any size of pathological images to enable more effective feature learning. Our approach entails (1) the incorporation of a plug-and-play high-resolution Vision Transformer (ViT) to enhance patch-wise WSI representation, enabling more detailed and comprehensive feature extraction, (2) the systematic evaluation of multiple advanced similarity metrics for comparing WSI-extracted features, optimizing the representation learning process to better capture tumor characteristics, (3) the demonstration that smaller image patches enhanced follow the proposed pipeline can achieve equivalent or superior prediction accuracy compared to raw larger patches, while significantly reducing computational overhead. Experimental findings valid that PathoHR provides the potential way of integrating enhanced image resolution with optimized feature learning to advance computational pathology, offering a promising direction for more accurate and efficient breast cancer survival prediction. Code will be available at https://github.com/AIGeeksGroup/PathoHR.

eess.IV↗

arXiv2026

QoS-Aware RACH Preamble Slicing via Quota-Projected Branching Deep Reinforcement Learning

Quality-of-service (QoS)-aware random access requires adaptive allocation of a finite random access channel (RACH) preamble budget across heterogeneous traffic and access procedures. This paper proposes QP-BD3QN-RACH, a quota-projected branching deep reinforcement learning controller for mixed two-step (2RA) and four-step (4RA) contention-based random access. Four action branches correspond to the delay-sensitive and delay-tolerant 2RA/4RA preamble pools. A branching dueling Double DQN selects pool-specific multipliers, and deterministic quota projection converts them to nonnegative integer allocations that preserve the preamble budget. With five actions per branch, the controller represents 625 pre-projection branch-action tuples using 20 branch-action outputs. Evaluation covers five arrival loads, cross-method comparison under nominal seed 42, six-seed sensitivity of QP-BD3QN-RACH, and targeted ablations. Across the five-load grid, its mean direction-aligned differences relative to four comparators are positive: 5.74 to 8.21 percentage points for success/collision, 1.23 to 1.92 percentage points for fallback, 0.35 to 0.68 percentage points for blocking, and 0.128 to 0.456 decision intervals for successful-access delay. Load-wise results exhibit metric-dependent tradeoffs, particularly under intermediate and overload conditions.

cs.NI↗

arXiv2026

MVC-Bench: Benchmarking Calibration of Medical Vision-Language Models

Reliable evaluation of vision-language models (VLMs) and medical vision-language models (Medical-VLMs) requires calibrated confidence, particularly under realistic clinical conditions. However, existing efforts mainly focused on improving accuracy, leaving calibration in the medical domain underexplored. To this end, we propose MVC-Bench, a calibration-centric benchmark for medical image classification with VLMs and Medical-VLMs. MVC-Bench assesses the calibration across three axes: (i) robustness to modality, backbone, and domain shift (ii) effectiveness of calibration strategies and prompt-tuning methods (iii) stability under prompt-template and random-seed variations. The benchmark covers eight different backbones, three medical modalities, including fundus imaging, histopathology, and chest X-ray under in-domain and domain shift settings. It compares post-hoc calibration, train-time calibration, and zero-shot inference methods, together with six prompt-tuning methods. Across more than 1638 controlled experiments, we report accuracy and Expected Calibration Error (ECE) as primary metrics, and further report results with complementary calibration measures, including Maximum Calibration Error (MCE) and Adaptive Calibration Error (ACE). We further investigate the underlying causes of miscalibration in VLMs and Medical-VLMs and propose a simple train-time calibration method, Multi-Class Margin (MCM) regularization, which achieves lowest ECE on 10 out of 12 settings in in-domain and remains competitive under domain shifts. Collectively, MVC-Bench provides a structured evaluation framework and actionable guidance for improving calibration in safety-critical medical workflows.

cs.CV↗

arXiv2026

Grounding Isn't Knowing: Do VLMs Need Object Localization for Spatial Reasoning?

Vision-language models (VLMs) can answer spatial questions, yet the mechanisms connecting object grounding to spatial reasoning remain poorly understood. It is underexplored whether spatial reasoning internally requires precise objects localization, or can bypass explicit localization through global layout cues. In this work, we investigate two representative model families, LLaVA-1.5 and Qwen2.5-VL, using a suite of mechanistic interpretability tools, including token ablation, layer-wise probing, attention knockout, and causal mediation analysis. We find that spatial relation prediction follows a staged grounding-to-reasoning process in which object-aligned tokens establish coarse target-reference anchors, while precise bounding-box boundaries are not required. Positional information becomes decodable before relation decisions emerge, and a small set of attention heads mediates the causal effects of both localization and spatial reasoning. The two tasks share early grounding-related processing but ultimately rely on partially distinct specialized pathways. Through rigorous experiments, we provide a token-, layer-, and head-level account of how VLMs transform object grounding into spatial relations, showing that knowing where objects are is not equivalent to knowing how they relate.

cs.CV↗

arXiv2026

Counterfactual Anatomy-guided Spatial-Temporal Decoding for Annotation-Free Hallucination Mitigation in Medical VLMs

Medical vision-language models (Med-VLMs) have demonstrated strong performance on medical visual question answering, yet they remain prone to hallucination, generating clinically unsupported statements that are insufficiently grounded in image evidence. Mitigation methods applied during decoding offer a practical solution, but they typically lack anatomical awareness or rely heavily on ground truth annotations, which limits their applicability. We propose Counterfactual Anatomy-guided Spatial-Temporal decoding (CAST), a framework that operates entirely during inference and requires no manual annotations for anatomically grounded hallucination mitigation. CAST automatically discovers anatomical regions relevant to the given query through broad medical segmentation. It then selects a compact, causally informative area using counterfactual intervention based on the drop in answer likelihood under occlusion. Guided by this chosen region, CAST performs a unified contrastive decoding process, combining classifier-free guidance to correct spatial attention with stepwise temporal contrast to regulate generation dynamics. Experiments on the SLAKE and MIMIC-CXR datasets across three Med-VLMs demonstrate that CAST consistently outperforms strong baselines and surpasses decoding strategies reliant on ground truth. Our results indicate that compact, automatically selected regions provide highly effective contrastive guidance without expert annotations, offering a practical and generalizable solution for improving spatial grounding and reducing hallucinations. Code is available at https://github.com/csyifan/CAST.

cs.CV↗

arXiv2026

On the Robustness of Temporal Vision-Language Models for Surgical Endoscopy Videos

Temporal vision-language models (TVLMs) offer a reusable, prompt-based interface for surgical video understanding, yet, their robustness under clinically realistic acquisition artifacts in endoscopy remains insufficiently characterized. In practice, degradations such as defocus, haze, motion blur, noise, cautery smoke, and packet loss introduce structured distribution shifts which may compromise video-text alignment. We study the robustness of temporal VLMs under such shifts caused by corruptions in clip frames. We introduce Endo-C6, a compact corruption benchmark of six endoscopy-realistic perturbations evaluated at a fixed high severity, and apply it to public Gastrointestinal (GI) endoscopy and laparoscopic cholecystectomy videos. Under a standardized prompt protocol, we benchmark 3 recent surgical TVLM baselines and analyze robustness in both mean and worst-case settings, spanning 294 dataset-level evaluations. Finally, we present RobustEndoCLIP, obtained by few-shot parameter-efficient tuning with VeRA, outperforming existing TVLM baselines. Our findings show that off-the-shelf TVLMs can exhibit severe worst-case collapse under endoscopy-specific corruptions, whereas lightweight few-shot adaptation can substantially improve corrupted performance and robustness without changing the prompt-based interface. We expect Endo-C6 to support standardized robustness reporting and promote more reliable clinical vision-language systems.

cs.CV↗

arXiv2026

Can Experts Adapt Without Training? On Test-Time Modality Generalization in MVLMs

Medical vision-language models (MVLMs) promise broad zero-shot generalization, yet their reliability collapses when confronted with unseen modalities and domains, precisely where clinical robustness matters most. To address this gap, we revisit test-time modality generalization from the perspective of Mixture-of-Experts (MoE) and ask: can experts route-and-adapt without any optimization during inference? We identify a fundamental specialization-generalization dilemma at test time, where blindly aggregating modality experts dilutes modality-specific knowledge, while selecting one highly confident expert risks mismatch under shift. To address this, we propose MoBE: a fully optimization-free framework that performs dynamic expert selection and adaptation at test time. MoBE combines entropy-guided dynamic routing in MoE settings with expert-wise Bayesian adaptation, enabling experts to update their confidence and adapt online without gradient updates. Without parametric updates, MoBE augments a static MVLM with test-time routing and online statistics, achieving average accuracy gains of +4.72, +7.17, and +4.3 over state-of-the-art TTA methods across seen, unseen, and heterogeneous medical benchmarks, highlighting the effectiveness of training-free expert adaptation for robust modality generalization.

cs.CV↗

arXiv2026

Super-Generalist: Towards Comprehensive and Accurate Medical Image Understanding via Generalist-Specialist Synergy

Medical images require comprehensive and accurate interpretation to support the diagnosis of diverse clincial conditions. Recent vision-language generalist models offer broad task coverage and promising zero-shot capabilities, yet often lack fine-grained anatomical and lesion awareness for reliable diagnosis and spatial interpretability. In contrast, supervised specialist models achieve strong performance on specific tasks but typically lack generalization across diseases and anatomies. In this work, we present SuG, a Super-Generalist framework that unifies generalist vision-language learning with specialist objectives, enabling both broad generalization and specialist-level diagnostic capability. We perform specialist-enhanced vision-language alignment in SuG by incorporating spatial priors from multiple segmentation experts, including anatomy, class-specific lesion and class-agnostic lesion segmentors that captures lesions beyond anatomies annotated during training. To improve lesion grounding capability, we leverage lesion masks as spatial priors to calibrate text-conditioned visual attention, encouraging disease-related semantics to focus on clinically relevant regions. We evaluate SuG on extensive chest and abdominal CT benchmarks, including CT-RATE, Merlin, MedVL-CT69K, and several in-house tumor datasets. SuG achieves state-of-the-art performance across a wide range of disease diagnosis tasks and surpasses specialist models on several critical tumor diagnosis benchmarks. Furthermore, SuG demonstrates strong lesion grounding capability, including robust generalization to lesion types lacking class-specific supervision.

cs.CV↗

arXiv2026

CA-GCL: Cross-Anatomy Global-Local Contrastive Learning for Robust 3D Medical Image Understanding

Fine-grained Vision-Language Pre-training (FVLP) demonstrates significant potential in 3D medical image understanding by aligning anatomy-level visual representations with corresponding textual descriptions. However, existing FVLP paradigms often suffer from severe representation collapse in the textual embedding space, where text embeddings of distinct anatomical structures become highly clustered and indistinguishable. This distributional degeneracy renders the model hypersensitive to prompt variations, hindering reliable clinical deployment. To address these challenges, we propose a novel Cross-Anatomy Global-Local Contrastive Learning framework (CA-GCL). CA-GCL introduces a global contrastive objective that enforces separation between anatomical categories in the latent space, effectively counteracting the aggregation tendency induced by local alignment. Furthermore, we incorporate a clinical-aware text augmentation strategy based on permutation invariance and partial completeness to enhance robustness against descriptive incompleteness. Extensive evaluations on the CT-RATE and Rad-ChestCT datasets show that CA-GCL achieves comparable zero-shot abnormality detection performance to existing VLP paradigms, while demonstrating substantially better robustness to prompt variations: on canonical templates it obtains higher mean AUC with lower variance, and on non-canonical templates it remains stable whereas baselines degrade markedly. These results validate CA-GCL as an effective framework for robust 3D medical image understanding.

cs.CV↗