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Artificial intelligence

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arXiv2025

Deformable Image Registration for Self-supervised Cardiac Phase Detection in Multi-View Multi-Disease Cardiac Magnetic Resonance Images

Cardiovascular magnetic resonance (CMR) is the gold standard for assessing cardiac function, but individual cardiac cycles complicate automatic temporal comparison or sub-phase analysis. Accurate cardiac keyframe detection can eliminate this problem. However, automatic methods solely derive end-systole (ES) and end-diastole (ED) frames from left ventricular volume curves, which do not provide a deeper insight into myocardial motion. We propose a self-supervised deep learning method detecting five keyframes in short-axis (SAX) and four-chamber long-axis (4CH) cine CMR. Initially, dense deformable registration fields are derived from the images and used to compute a 1D motion descriptor, which provides valuable insights into global cardiac contraction and relaxation patterns. From these characteristic curves, keyframes are determined using a simple set of rules. The method was independently evaluated for both views using three public, multicentre, multidisease datasets. M&Ms-2 (n=360) dataset was used for training and evaluation, and M&Ms (n=345) and ACDC (n=100) datasets for repeatability control. Furthermore, generalisability to patients with rare congenital heart defects was tested using the German Competence Network (GCN) dataset. Our self-supervised approach achieved improved detection accuracy by 30% - 51% for SAX and 11% - 47% for 4CH in ED and ES, as measured by cyclic frame difference (cFD), compared with the volume-based approach. We can detect ED and ES, as well as three additional keyframes throughout the cardiac cycle with a mean cFD below 1.31 frames for SAX and 1.73 for LAX. Our approach enables temporally aligned inter- and intra-patient analysis of cardiac dynamics, irrespective of cycle or phase lengths. GitHub repository: https://github.com/Cardio-AI/cmr-multi-view-phase-detection.git

cs.CV↗

arXiv2026

Humanity's Last Exam

Benchmarks are important tools for tracking the rapid advancements in large language model (LLM) capabilities. However, benchmarks are not keeping pace in difficulty: LLMs now achieve over 90\% accuracy on popular benchmarks like MMLU, limiting informed measurement of state-of-the-art LLM capabilities. In response, we introduce Humanity's Last Exam (HLE), a multi-modal benchmark at the frontier of human knowledge, designed to be the final closed-ended academic benchmark of its kind with broad subject coverage. HLE consists of 2,500 questions across dozens of subjects, including mathematics, humanities, and the natural sciences. HLE is developed globally by subject-matter experts and consists of multiple-choice and short-answer questions suitable for automated grading. Each question has a known solution that is unambiguous and easily verifiable, but cannot be quickly answered via internet retrieval. State-of-the-art LLMs demonstrate low accuracy and calibration on HLE, highlighting a significant gap between current LLM capabilities and the expert human frontier on closed-ended academic questions. To inform research and policymaking upon a clear understanding of model capabilities, we publicly release HLE at https://lastexam.ai.

cs.LG↗

arXiv2026

Balancing Centralized Learning and Distributed Self-Organization: A Hybrid Model for Embodied Morphogenesis

Background: both embodied intelligence and developmental morphogenesis depend on a division of labour between centralized guidance and distributed material dynamics, but the amount of top-down control needed to steer self-organization remains unclear. Methods: we coupled a compact full-resolution convolutional controller to a differentiable Gray-Scott reaction-diffusion (RD) substrate. The controller observes two fields, U and V, and applies smooth gain-scheduled modulations of the feed and kill parameters (Delta F and Delta K). We compared pure RD, neural network (NN)-dominant and hybrid regimes and evaluated spectral selectivity, convergence and control cost. Results: the hybrid regime achieved 100% strict convergence at approximately 165 steps, whereas pure RD and the NN-dominant baseline did not converge within the same horizon. It matched the substrate's spectral selectivity while using approximately 15 times less L1 effort and over 200 times less L2 power than the NN-dominant controller. Moderate amplitudes (A approximately 0.03-0.045) formed a Goldilocks zone with 100% quasi-convergence in 94-96 steps. Conclusions: effective control is best framed as seed then cede: brief, smooth parameter-level nudges place the system in a favourable basin of attraction, after which reaction-diffusion dynamics complete and stabilize the pattern. This provides a quantitative model of morphological computation for controlled self-organization.

cs.AI↗

arXiv2012

Gray Image extraction using Fuzzy Logic

Fuzzy systems concern fundamental methodology to represent and process uncertainty and imprecision in the linguistic information. The fuzzy systems that use fuzzy rules to represent the domain knowledge of the problem are known as Fuzzy Rule Base Systems (FRBS). On the other hand image segmentation and subsequent extraction from a noise-affected background, with the help of various soft computing methods, are relatively new and quite popular due to various reasons. These methods include various Artificial Neural Network (ANN) models (primarily supervised in nature), Genetic Algorithm (GA) based techniques, intensity histogram based methods etc. providing an extraction solution working in unsupervised mode happens to be even more interesting problem. Literature suggests that effort in this respect appears to be quite rudimentary. In the present article, we propose a fuzzy rule guided novel technique that is functional devoid of any external intervention during execution. Experimental results suggest that this approach is an efficient one in comparison to different other techniques extensively addressed in literature. In order to justify the supremacy of performance of our proposed technique in respect of its competitors, we take recourse to effective metrics like Mean Squared Error (MSE), Mean Absolute Error (MAE), Peak Signal to Noise Ratio (PSNR).

cs.CV↗

arXiv2026

Latent Space Probing for Adult Content Detection in Video Generative Models

The rapid proliferation of AI-powered video generation systems has introduced significant challenges in content moderation, particularly with respect to adult and sexually explicit material. Existing detection methods operate on either prompts or decoded pixel-space outputs. Therefore, both approaches are blind to the rich internal representations formed during generation. In this paper, we propose a novel latent space probing framework that intercepts the denoised latent representations produced by the CogVideoX video diffusion model during inference and attaches lightweight classifiers to perform real-time adult content detection. To support this work, we construct a large-scale binary dataset of 11039 ten-second video clips (5086 violating, 5953 non-violating) sourced from adult websites and YouTube respectively. We introduce two lightweight probing classifier architectures. We train and evaluate it on the dataset. Our work demonstrates that latent-space signals encode strong discriminative features for harmful content detection, achieving 97.29% F1 on our held-out test set with an overhead in the 4-6ms range. Our results suggest that probing the latent space results in improvements in both detection performance as well as cost.

cs.CV↗

arXiv2026

Hallucinations and Truth: A Comprehensive Accuracy Evaluation of RAG, LoRA and DoRA

Recent advancements in Generative AI have significantly improved the efficiency and adaptability of natural language processing (NLP) systems, particularly through Retrieval-Augmented Generation (RAG), Low-Rank Adaptation (LoRA), and Weight-Decomposed Low-Rank Adaptation (DoRA). RAG integrates external knowledge to enhance factual consistency in generative outputs, while LoRA enables parameter-efficient fine-tuning of large language models (LLMs). DoRA further refines this process by optimizing fine-tuning through adaptive parameter ranking and domain-aware weight adjustments, improving learning efficiency while maintaining inference performance. This paper presents a large-scale empirical evaluation of RAG, LoRA, and DoRA, with model fine-tuning and generation performance assessed on 20,000 FAQ-based queries, while the knowledge base spans 400,000 entries. The study analyzes key performance metrics such as accuracy, relevance, and inference latency. Experimental results demonstrate that DoRA achieves the highest accuracy (90.1%), relevance score (0.88), and lowest latency (110 ms per query), outperforming both LoRA and RAG in real-world, domain-specific generative AI applications. Furthermore, this study examines the trade-offs between fine-tuning efficiency, computational cost, and real-time adaptability across different models. Findings highlight RAG's effectiveness in knowledge grounding, LoRA's cost-efficient domain adaptation, and DoRA's ability to balance fine-tuning efficiency with model precision. These insights provide practical guidance for deploying AI-driven generative systems in accuracy-critical domains such as healthcare, finance, and legal services, ensuring scalability, reliability, and optimal performance in dynamic environments.

cs.CL↗

arXiv2026

LLM-Guided Initialization for Accelerated Hybrid Quantum-Classical Medical Image Classification

Variational quantum algorithms often encounter barren plateaus, where cost gradients decay rapidly with increasing circuit depth, undermining the trainability of parameterized quantum circuits. This paper evaluates AdaInit (Adaptive Initialization), proposed by Zhuang and Cunningham, which uses large language models to propose initial parameters for quantum neural networks. We study a simplified single-query AdaInit variant paired with GPU-accelerated simulation in NVIDIA CUDA-Q and apply it to binary classification on the DMR-IR mammography dataset. AdaInit delivers 14.6 times higher gradient variance at initialization than random initialization (0.0095 vs. 0.0006), producing 160 times faster convergence (1.1s vs. 176 s) while maintaining the same classification accuracy of 61.4 percent. We provide theoretical analysis grounded in the geometry of parameterized circuit landscapes and show empirically that LLM-guided initialization places the optimizer in trainable regions of parameter space. Beyond performance, our results indicate that a single LLM query can yield informative parameters without iterative refinement, suggesting a low-overhead path to improved trainability. The findings validate AdaInit in a medical imaging setting and demonstrate its compatibility with GPU-accelerated quantum backends for practical speedups.

quant-ph↗

arXiv2026

The SpiNNaker2 chip: a many-core platform for flexible and scalable brain-inspired computing

In deep learning, efficiency gets more and more important to compensate for the ongoing growth in model sizes and applications. Neuromorphic hardware has long been advocated as an upcoming alternative to deep networks, taking inspiration from the brain for achieving unprecedented energy efficiency. However, demonstrations of these gains only recently began to grow in complexity and real-world applicability. With SpiNNaker2, we present a chip that bridges the gap between deep networks and neuromorphic computing and allows for flexible exploration of computing approaches that combine both worlds. It features 152 processing elements equipped with an ARM M4F processor and dedicated accelerators, an extended SpiNNaker routing fabric for scalable event-based communication and a range of external interfaces for system integration, including Gbit Ethernet and an LPDDR4 memory interface. We demonstrate performance and efficiency of the SpiNNaker2 chip for neuromorphic and deep network workloads, as well as novel event-based computing approaches. For deep network workloads, the chip achieves up to 4.5 TOPS in high performance mode and up to 2.7 TOPS/W efficiency in high efficiency mode for INT8 workloads. The chip supports spiking neural networks with >150000 neurons and >1.8 billion synaptic events/s when simulated with a 1 ms time step. Its low baseline power of less than 250 mW allows for efficiency even under varying workload conditions, allowing to explore sparse and event-based modes of computation. All this demonstrates the chip's capabilities as a universal hardware platform for scalable brain-inspired computing and its combinations with mainstream deep network approaches.

cs.ET↗

arXiv2026

OPERA: Offline Policy-guided Expert Routing and Adaptation for Universal Biomedical Image Analysis

Biomedical image analysis spans diverse modalities and tasks, yet real-world deployment is hindered by severe distribution shifts across scanners, protocols, and patient populations. High-performing models consequently require repeated domain-specific fine-tuning, which is a costly cycle that becomes impractical when labels are scarce or privacy constraints limit data sharing. We propose OPERA (Offline Policy-guided Expert Routing and Adaptation), a multi-agent ensemble framework that addresses this deployment bottleneck by treating expert weight assignment as an offline policy learning problem: a routing policy is learned from a small validation set without gradient updates to any expert agent, then deployed with test-time adaptation to handle distribution shift. OPERA coordinates heterogeneous specialist agents through complementary mechanisms. The expert profiling module learns selection policies offline, enabling informed allocation of expertise. Each agent undergoes confidence calibration through temperature adjustment, ensuring more reliable probabilistic outputs. OPERA also incorporates distribution aware adaptation, where class weights are dynamically adjusted at the batch level using statistics derived from unlabeled test data. Instance level routing assigns each sample to the most suitable expert by leveraging inter model agreement and predictive entropy. We evaluate OPERA on 9 datasets covering fundus photography, chest X-ray, CT, MRI, and multimodal diagnostic benchmarks, comparing against 30+ baselines across classification, segmentation, and multimodal settings. OPERA consistently improves performance and calibration quality, demonstrating that offline policy-guided expert agents coordination is a practical path to deployable biomedical AI without retraining. Code is on \href{https://github.com/HUANGLIZI/OPERA}{GitHub}.

cs.CV↗

arXiv2026

HOBA: Hierarchical On-Policy Bidding Agents for Adaptive Online Advertising

Online advertising bidding systems typically deploy multiple offline-trained expert models (e.g., PID controllers, model predictive control, offline RL policies) but face two critical limitations: lack of online adaptability to non-stationary auction markets, and reliance on costly manual tuning of hyperparameters such as bid bounds and budget pacing constraints. We propose HOBA (Hierarchical On-policy Bidding Agents), a hierarchical reinforcement learning framework that decouples strategic reasoning, model selection, and bid execution across three time scales. At the high level, a large language model infers hyperparameters from contextual signals through a Think-Act-Observe-Reflect loop with historical experience retrieval. At the mid level, a SARSA agent dynamically selects among expert models, incorporating causal adjustment to eliminate selection bias. At the low level, a dynamic expert pool (PID, MPC, IQL, Decision Transformer) executes bids under high-level constraints. This design confines online learning to discrete expert selection rather than continuous bid optimization, significantly reducing exploration risk while maintaining adaptability. Experiments on the AuctionNet benchmark and a large-scale A/B test demonstrate consistent improvements over state-of-the-art baselines. In a large-scale online deployment, HOBA delivered substantial business value, achieving a +3.6\% increase in target cost, proving the effectiveness of our hierarchical multi-agent bidding paradigm.

cs.AI↗

arXiv2026

Do Visual Features Improve Other-Initiated Repair Detection? A Dyadic Multimodal Approach

Other-initiated Self-repair, or in short Other-initiated Repair (OIR), is an essential mechanism in conversational interaction, whereby a recipient signals a problem in speaking, hearing, or understanding, prompting the previous speaker to resolve it. In the case of conversational agents, it is essential to accurately identify these repair initiation strategies to address communication breakdowns efficiently. While conversational analysis studies have shown that OIR initiation is accompanied by both verbal and non-verbal signals such as gaze shifts, facial expressions, body postures, and hand gestures, existing computational approaches rely mainly on text and audio. This paper introduces a novel multimodal model for OIR detection and classification, incorporating a set of visual features drawn from conversation analysis. We evaluate our approach on two corpora with distinct languages and interaction settings. Results demonstrate that visual information consistently improves performance over text and audio baselines, and provide insights into cross-modal feature contributions across two corpora.

cs.AI↗

arXiv2026

Real-time Spatial Retrieval Augmented Generation for Urban Environments

The proliferation of Generative Artificial Ingelligence (AI), especially Large Language Models, presents transformative opportunities for urban applications through Urban Foundation Models. However, base models face limitations, as they only contain the knowledge available at the time of training, and updating them is both time-consuming and costly. Retrieval Augmented Generation (RAG) has emerged in the literature as the preferred approach for injecting contextual information into Foundation Models. It prevails over techniques such as fine-tuning, which are less effective in dynamic, real-time scenarios like those found in urban environments. However, traditional RAG architectures, based on semantic databases, knowledge graphs, structured data, or AI-powered web searches, do not fully meet the demands of urban contexts. Urban environments are complex systems characterized by large volumes of interconnected data, frequent updates, real-time processing requirements, security needs, and strong links to the physical world. This work proposes a real-time spatial RAG architecture that defines the necessary components for the effective integration of generative AI into cities, leveraging temporal and spatial filtering capabilities through linked data. The proposed architecture is implemented using FIWARE, an ecosystem of software components to develop smart city solutions and digital twins. The design and implementation are demonstrated through the use case of a tourism assistant in the city of Madrid. The use case serves to validate the correct integration of Foundation Models through the proposed RAG architecture.

cs.AI↗

arXiv2026

A Survey of Graph Transformers: Architectures, Theories and Applications

Graph Transformers (GTs) have demonstrated a strong capability in modeling graph structures by addressing the intrinsic limitations of graph neural networks (GNNs), such as over-smoothing and over-squashing. Recent studies have proposed diverse architectures, enhanced explainability, and practical applications for Graph Transformers. In light of these rapid developments, we conduct a comprehensive review of Graph Transformers, covering aspects such as their architectures, theoretical foundations, and applications. In this survey, we first categorize the architecture of Graph Transformers according to their strategies for processing structural information, including graph tokenization, positional encoding, structure-aware attention, and model ensemble. Then, from the theoretical perspective, we examine the expressivity of Graph Transformers in various discussed architectures and contrast them with other advanced graph learning algorithms to discover their connections. For applications, we organize the literature around four graph organization forms, from relational, geometric, dynamic to heterogeneous. A Practical Guidance table then maps architectural components to these graph forms by adoption frequency, so practitioners can narrow down which design families to consider for a given input structure. Lastly, we will discuss the current challenges and prospective directions in Graph Transformers for potential future research.

cs.LG↗

arXiv2026

GraphDx: A Cost-Aware Knowledge-Enhanced Multi-Agent Framework for Sequential Diagnosis

Sequential diagnosis requires balancing diagnostic accuracy against resource costs through iterative information gathering. Existing Large Language Model (LLM) approaches exhibit a critical knowledge-reasoning gap: despite encoding extensive medical knowledge, they struggle to reason systematically under cost constraints, often resorting to excessive testing. We propose GraphDx, a knowledge-enhanced framework with two core innovations. First, we design an automated pipeline that leverages LLMs to construct Medical Diagnosis Knowledge Graphs (MDKGs) with quantized typicality, action-centric topology, and dual-objective attributes for both diagnostic relevance and cost-sensitivity. Second, we introduce three collaborative agents (Perception, Reasoning, and Decision) where the Perception and Decision Agents handle language understanding and generation, while the Reasoning Agent performs deterministic evidence scoring and cost-aware planning on the MDKG. Experiments on MedQA and MIMIC-IV across three LLM backbones (DeepSeek-V3, Kimi-k2, Llama-3.3) show that GraphDx improves diagnostic success rates from 50--68% to 79--93% while reducing test costs by 20--54%, providing a robust, economical, and interpretable solution for automated clinical diagnosis.

cs.AI↗

arXiv2026

Concept Tokens: Learning Behavioral Embeddings Through Concept Definitions

We propose Concept Tokens, a lightweight method that adds a new special token to a pretrained LLM and learns only its embedding from multiple natural language definitions of a target concept, where occurrences of the concept are replaced by the new token. The LLM is kept frozen and the embedding is optimized with the standard language-modeling objective. We evaluate Concept Tokens in three settings. First, we study hallucinations in closed-book question answering on HotpotQA and find a directional effect: negating the hallucination token reduces hallucinated answers mainly by increasing abstentions, whereas asserting it increases hallucinations and lowers precision. Second, we induce recasting, a pedagogical feedback strategy for second language teaching, and observe the same directional effect. Moreover, compared to providing the full definitional corpus in-context, concept tokens better preserve compliance with other instructions (e.g., asking follow-up questions). Finally, we include a qualitative study with the Eiffel Tower and a fictional "Austral Tower" to illustrate what information the learned embeddings capture and where their limitations emerge. Overall, Concept Tokens provide a compact control signal learned from definitions that can steer behavior in frozen LLMs.

cs.CL↗

arXiv2026

Beyond Single Plots: A Benchmark for Question Answering on Multi-Charts

Charts are widely used to present complex information. Deriving meaningful insights in real-world contexts often requires interpreting multiple related charts together. Research on understanding multi-chart images has not been extensively explored. We introduce PolyChartQA, a mid-scale dataset specifically designed for question answering over multi-chart images. PolyChartQA comprises 534 multi-chart images (with a total of 2,297 sub-charts) sourced from peer-reviewed computer science research publications and 2,694 QA pairs. We evaluate the performance of nine state-of-the-art Multimodal Language Models (MLMs) on PolyChartQA across question type, difficulty, question source, and key structural characteristics of multi-charts. Our results show a 27.4% LLM-based accuracy (L-Accuracy) drop on human-authored questions compared to MLM-generated questions, and a 5.39% L-accuracy gain with our proposed prompting method.

cs.CL↗

arXiv2026

PrinciplismQA: A Philosophy-Grounded Approach to Assessing LLM-Human Clinical Medical Ethics Alignment

As medical LLMs transition to clinical deployment, assessing their ethical reasoning capability becomes critical. While achieving high accuracy on knowledge benchmarks, LLMs lack validated assessment for navigating ethical trade-offs in clinical decision-making where multiple valid solutions exist. Existing benchmarks lack systematic approaches to incorporate recognized philosophical frameworks and expert validation for ethical reasoning assessment. We introduce PrinciplismQA, a philosophy-grounded approach to assessing LLM clinical medical ethics alignment. Grounded in Principlism, our approach provides a systematic methodology for incorporating clinical ethics philosophy into LLM assessment design. PrinciplismQA comprises 3,648 expert-validated questions spanning knowledge assessment and clinical reasoning. Our expert-calibrated pipeline enables reproducible evaluation and models ethical biases. Evaluating recent models reveals significant ethical reasoning gaps despite high knowledge accuracy, demonstrating that knowledge-oriented training does not ensure clinical ethical alignment. PrinciplismQA provides a validated tool for assessing clinical AI deployment readiness. Our data and test scripts are fully released on https://github.com/FreedomIntelligence/PrinciplismQA.

cs.CL↗

arXiv2026

DICA: Dual-Indicator Guided Contrastive Alignment in Multimodal Large Language Models

Human visual reasoning typically follows a coarse-to-fine attention process, starting from global scene understanding and gradually focusing on question-relevant regions. However, multimodal large language models may deviate from this pattern due to attention drift and the underutilization of visual evidence, which can lead to hallucinations. To mitigate these issues, this study proposes a Dual-Indicator Guided Contrastive Alignment (DICA), which tracks two information-theoretic indicators during inference: Visual Attention Entropy (VAE), which reflects the concentration of visual attention, and Output Image Correlation (OIC), which measures the dependence of generated outputs on the visual input. An abnormal increase in VAE or a decrease in OIC corresponds to different failure modes, which trigger targeted contrastive alignment to restore visual grounding. Experimental results across multiple benchmarks demonstrate that DICA consistently outperforms existing approaches and substantially reduces hallucinations, highlighting the effectiveness of indicator-driven intervention in improving multimodal inference reliability. The code is publicly available at https://github.com/BGWH123/DICA/.

cs.AI↗