Position: Intelligent Science Laboratory Requires the Integration of Cognitive and Embodied AI

Sha Zhang; Suorong Yang; Tong Xie; Xiangyuan Xue; Zixuan Hu; Rui Li; Wenxi Qu; Zhenfei Yin; Tianfan Fu; Di Hu; Andres M Bran; Nian Ran; Bram Hoex; Wangmeng Zuo; Philippe Schwaller; Wanli Ouyang; Lei Bai; Yanyong Zhang; Lingyu Duan; Shixiang Tang; Dongzhan Zhou

arXiv · 2506.19613

Position: Intelligent Science Laboratory Requires the Integration of Cognitive and Embodied AI

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Abstract

Scientific discovery has long been constrained by human limitations in expertise, physical capability, and sleep cycles. The recent rise of AI scientists and automated laboratories has accelerated both the cognitive and operational aspects of research. However, key limitations persist: AI systems are often confined to virtual environments, while automated laboratories lack the flexibility and autonomy to adaptively test new hypotheses in the physical world. Recent advances in embodied AI, such as generalist robot foundation models, diffusion-based action policies, fine-grained manipulation learning, and sim-to-real transfer, highlight the promise of integrating cognitive and embodied intelligence. This convergence opens the door to closed-loop systems that support iterative, autonomous experimentation and the possibility of serendipitous discovery. In this position paper, we propose the paradigm of Intelligent Science Laboratories (ISLs): a multi-layered, closed-loop framework that deeply integrates cognitive and embodied intelligence. ISLs unify foundation models for scientific reasoning, agent-based workflow orchestration, and embodied agents for robust physical experimentation. We argue that such systems are essential for overcoming the current limitations of scientific discovery and for realizing the full transformative potential of AI-driven science.

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Sha Zhang, Suorong Yang, Tong Xie, Xiangyuan Xue, Zixuan Hu, Rui Li, Wenxi Qu, Zhenfei Yin, Tianfan Fu, Di Hu, Andres M Bran, Nian Ran, Bram Hoex, Wangmeng Zuo, Philippe Schwaller, Wanli Ouyang, Lei Bai, Yanyong Zhang, Lingyu Duan, Shixiang Tang, Dongzhan Zhou. 2025-06-24. Position: Intelligent Science Laboratory Requires the Integration of Cognitive and Embodied AI. https://arxiv.org/abs/2506.19613

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